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README.md
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pipeline_tag: tabular-classification
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repo: https://github.com/KDrewLab/DirectContacts2_analysis.git
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---
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#
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Proteins carry out cellular functions by self-assembling into functional complexes, a process that depends on direct physical interactions
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between components. While tools like AlphaFold and RoseTTAFold have advanced structure prediction, they remain limited in scaling to the full
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human proteome. DirectContacts2 addresses this challenge by integrating diverse large-scale protrin interaction datasets, including AP/MS (BioPlex1–3, Boldt et al., Hein et al.),
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This can be downloaded using the following:
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$ pip install autogluon==0.
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Then it can be imported as:
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>>> from autogluon.tabular import TabularPredictor
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Note that to perform operations with our model the **0.
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To use the model and make predictions, we show two full code examples using the [full feature matrix]()
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and the [test feature matrix]() in jupyter notebooks.
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pipeline_tag: tabular-classification
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repo: https://github.com/KDrewLab/DirectContacts2_analysis.git
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---
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# DirectContacts2: A network of direct physical protein interactions derived from high throughput mass spectrometry experiments
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Proteins carry out cellular functions by self-assembling into functional complexes, a process that depends on direct physical interactions
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between components. While tools like AlphaFold and RoseTTAFold have advanced structure prediction, they remain limited in scaling to the full
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human proteome. DirectContacts2 addresses this challenge by integrating diverse large-scale protrin interaction datasets, including AP/MS (BioPlex1–3, Boldt et al., Hein et al.),
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This can be downloaded using the following:
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$ pip install autogluon==0.8.2
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Then it can be imported as:
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>>> from autogluon.tabular import TabularPredictor
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Note that to perform operations with our model the **0.8.2 version** must be used
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To use the model and make predictions, we show two full code examples using the [full feature matrix]()
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and the [test feature matrix]() in jupyter notebooks.
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