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README.md
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- split: train
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path: data/train-*
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- split: train
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path: data/train-*
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---
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# Dataset Description
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This dataset was used for evaluated the different models on the masking exercise, i.e. measuring how well the different models are able to recover the original character.
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## Dataset Overview
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The dataset is compiled from the RefSeq database and other sources, focusing on ESKAPE pathogens. The genomic features were sampled randomly, followed by contigous segmentation.
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This dataset contains various different segment with lengths: [128, 256, 512, 1024].
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The segments were randomly selected and one of the characters were replace by * (masked_segment column). The reference_segment contains the original, non-replaced nucleotides.
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We performed 10000 masking per set, maximum of 2000 genomic feeatures. Only the genomic features: 'CDS', 'intergenic', 'pseudogene', 'ncRNA' features were considered.
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## Data Fields
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- `reference_segment_id`: A mapping of segment identifiers to their respective reference IDs in the database.
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- `masked_segment`: The DNA sequence of the segment with certain positions masked (marked with '*') for prediction or testing purposes.
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- `position_to_mask`: The specific position(s) in the sequence that have been masked, indicated by index numbers.
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- `masked_segment_id`: Unique identifiers assigned to the masked segments. (only unique with respect to length)
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- `contig_id`: Identifier of the contig to which the segment belongs.
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- `segment_id`: Unique identifier for each genomic segment. (reference segment id)
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- `strand`: The DNA strand of the segment, indicated as '+' (positive) or '-' (negative).
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- `seq_start`: Starting position of the segment within the contig.
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- `seq_end`: Ending position of the segment within the contig.
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- `segment_start`: Starting position of the genomic segment in the sequence.
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- `segment_end`: Ending position of the genomic segment in the sequence.
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- `label`: Category label for the genomic segment (e.g., 'CDS', 'intergenic').
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- `segment_length`: The length of the genomic segment.
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- `original_segment`: The original genomic sequence without any masking.
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## Usage
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This dataset is intended for academic and research purposes. Users are encouraged to apply this dataset in the development and evaluation of bioinformatics models, especially those related to genomic studies.
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## Citation
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If you use the code or data in this package, please cite:
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```bibtex
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@Article{ProkBERT2024,
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author = {Ligeti, Balázs and Szepesi-Nagy, István and Bodnár, Babett and Ligeti-Nagy, Noémi and Juhász, János},
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journal = {Frontiers in Microbiology},
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title = {{ProkBERT} family: genomic language models for microbiome applications},
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year = {2024},
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volume = {14},
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URL={https://www.frontiersin.org/articles/10.3389/fmicb.2023.1331233},
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DOI={10.3389/fmicb.2023.1331233},
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ISSN={1664-302X}
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}
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```
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