diff --git "a/uspto_condition/USPTO_condition.csv" "b/uspto_condition/USPTO_condition.csv"
new file mode 100644--- /dev/null
+++ "b/uspto_condition/USPTO_condition.csv"
@@ -0,0 +1,10001 @@
+source,canonical_rxn,catalyst1,solvent1,solvent2,reagent1,reagent2,dataset
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+US20130310411A1,COc1ccc(S)cc1.Clc1c2ccccc2nc2cccc(Br)c12>>COc1ccc(Sc2c3ccccc3nc3cccc(Br)c23)cc1,,CN(C)C=O,,[H-].[Na+],,test
+US20160137636A1,O=C1CCC(=O)N1Br.O=c1[nH]ccc2ccc(SCc3ccccc3)cc12>>O=c1[nH]cc(Br)c2ccc(SCc3ccccc3)cc12,,O,,CC#N,,test
+US20120065212A1,COC(=O)c1ncc(F)c(-c2ccc(Cl)cc2)n1.OCC(F)(F)F>>COC(=O)c1ncc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)n1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
+US20120040984A1,CCOC(=O)[C@@H]1CC[C@@H](Nc2ccc(C(=O)Nc3nnc(Cc4ccccc4)s3)cc2)CC1>>O=C(Nc1nnc(Cc2ccccc2)s1)c1ccc(N[C@@H]2CC[C@@H](C(=O)O)CC2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
+US20050075339A1,CC1(C)NN(c2ccccc2)NC1=O.O=C(O)C(=O)Cc1c(F)cccc1F>>O=c1[nH]c(=O)n(-c2ccccc2)nc1Cc1c(F)cccc1F,O=S(=O)(O)O,,,C1COCCO1,,test
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+US06756373B1,CC(N)=NO.CCCc1c2nc(-c3cc(I)cnc3OCC(C)C)[nH]c(=O)c2nn1C.[C]=O>>CCCc1c2nc(-c3cc(-c4nc(C)no4)cnc3OCC(C)C)[nH]c(=O)c2nn1C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
+US20030168970A1,CC(=O)c1ccc(B(O)O)cc1.CC1(C)CC2(CC(C)(C)c3ccc(OS(=O)(=O)C(F)(F)F)cc32)c2cc(OS(=O)(=O)C(F)(F)F)ccc21.CCO.Cc1ccccc1>>CC(=O)c1ccc(-c2ccc3c(c2)C2(CC3(C)C)CC(C)(C)c3ccc(-c4ccc(C(C)=O)cc4)cc32)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
+US20110263626A1,O=Cc1ccc(F)cc1.Oc1ccc(Br)cc1Cl>>O=Cc1ccc(Oc2ccc(Br)cc2Cl)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
+US20040072853A1,N#CN.Nc1ccccc1.O=[N+]([O-])O>>NC(=[NH2+])Nc1ccccc1.O=[N+]([O-])[O-],,CCO,,,,test
+US20110183985A1,Brc1ncnc2[nH]cnc12.CC(N)c1cc(Cl)c2cccnc2c1N1CCC[C@H](O)C1>>CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c2cccnc2c1N1CCC[C@H](O)C1,,CCO,,CCN(C(C)C)C(C)C,,test
+US20020107251A1,Nc1cccc(-n2c(=O)c(Cc3cccnc3)nc3cccnc32)c1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>O=C(Nc1cccc(-n2c(=O)c(Cc3cccnc3)nc3cccnc32)c1)c1cc(Cl)cc(Cl)c1,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,O=C([O-])O.[Na+],test
+US20150238601A1,Cc1cc2[nH]ncc2cc1N.Clc1ccnc(Cl)n1>>Cc1cc2[nH]ncc2cc1Nc1ccnc(Cl)n1,,CCO,,Cl,,test
+US20150148311A1,O=C(Cl)C1(CCl)CC1.c1ccc2c(c1)NCCN2C1CC1>>O=C(N1CCN(C2CC2)c2ccccc21)C1(CCl)CC1,,ClCCl,,CCN(CC)CC,,test
+US04954508,CCOC(=O)C(=Cc1ccccc1C)C(C)=O.Cl.Cn1nc(-c2ccccc2)cc1N>>CCOC(=O)C1=C(C)Nc2c(c(-c3ccccc3)nn2C)C1c1ccccc1C.Cl,,CCO,,CO,,test
+US20110275611A1,CNc1nc(-c2cc(F)c(C#N)c(SC)c2)cc(N2CCOC[C@H]2C)n1.NN>>CNc1nc(-c2cc(SC)c3c(N)n[nH]c3c2)cc(N2CCOC[C@H]2C)n1,,CCO,,CCN(C(C)C)C(C)C,,test
+US04296120,C=C(CC(=O)O)C(=O)O.CCCCCCCCNC(=O)C(C)=Cc1cccc(N)c1>>CCCCCCCCNC(=O)C(C)=Cc1cccc(N2CC(C(=O)O)CC2=O)c1,,CCOC(C)=O,,,,test
+US20090124601A1,CC1(C)OC(=O)C(C(=O)Cc2cc(F)c(F)cc2F)C(=O)O1.O=C1NCCCNC1CC(F)(F)F>>O=C(CC(=O)N1CCCNC(=O)C1CC(F)(F)F)Cc1cc(F)c(F)cc1F,,CC#N,,CCN(C(C)C)C(C)C,,test
+US20120329785A1,CN1CCC(N(C)c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3ccc(N(C)C4CCN(C)CC4)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
+US20100105900A1,C[N+](C)(C)C[C@@H](CC(=O)[O-])NC(=O)c1cccc(C#Cc2ccccc2)c1>>C[N+](C)(C)C[C@@H](CC(=O)[O-])NC(=O)c1cccc(CCc2ccccc2)c1,[Pd],,,,,test
+US20120142735A1,COCCn1ccc2c(Cl)ccc(OC(F)(F)F)c21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COCCn1cc(C(=O)C(F)(F)F)c2c(Cl)ccc(OC(F)(F)F)c21,,CN(C)C=O,,,,test
+US20150299179A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC(=O)[O-])ns2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N)ns2)cc1C#N.Cl,,C1COCCO1,CCOCC,,,test
+US04183933,C=O.CNC.Cc1cnc(C)cn1>>Cc1cnc(CCN(C)C)cn1,,O,,Cl,[Na+].[OH-],test
+US20070110816A1,C1CCCCC1.CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCO)cc1>>C1CCCCC1.CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCO)cc1,,C1CCCCC1,,,,test
+US20070249648A1,CC(C)(C)OC(=O)N1CCC2(CC1)CCN(C(=O)c1ccccc1)CC2>>O=C(c1ccccc1)N1CCC2(CCNCC2)CC1,,O=C(O)C(F)(F)F,,,,test
+US20120289702A1,Fc1ccc2cccnc2c1F.O=C1CCC(=O)N1I>>Fc1ccc2cc(I)cnc2c1F,,CC(=O)O,,,,test
+US04837333,C=CCBr.COc1ccc(CC[Mg]I)cc1>>C=CCCCc1ccc(OC)cc1,,C1CCOC1,,,,test
+US20120142717A1,CCOC(=O)/C(=C\O)CC.N=C(N)OCCc1cc(F)c(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1>>CCc1c[nH]c(OCCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20060264429A1,Cc1ccc2c(N3CCN(CC(=O)c4ccc5c(c4)NC(=O)CO5)CC3)cc(Cl)cc2n1>>Cc1ccc2c(N3CCN(CC(O)c4ccc5c(c4)NC(=O)CO5)CC3)cc(Cl)cc2n1,,CO,ClCCl,[BH4-].[Na+],,test
+US20090192156A1,CC(C)(C)OC(=O)N1CCC(OCCN2CCCCC2)CC1>>C1CCN(CCOC2CCNCC2)CC1,,C1COCCO1,CO,Cl,,test
+US20080009482A1,C=CC(=O)NC.COCCN>>CNC(=O)CCNCCOC,,CO,,CCO,,test
+US04536518,COc1ccc(C2(O)CCCc3ccccc32)cc1>>COc1ccc(C2=CCCc3ccccc32)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
+US20110166129A1,BrP(Br)Br.OCc1cccc(Br)n1>>BrCc1cccc(Br)n1,,ClCCl,,,,test
+US05077303,COC=C(C(=O)OC)c1ccccc1C=Cc1ccccc1.O=C(OO)c1cccc(Cl)c1>>COC=C(C(=O)OC)c1ccccc1[C@@H]1O[C@H]1c1ccccc1,,ClCCl,,,,test
+US04399141,C=C1c2ccccc2CC(=NO)c2ccccc21>>C=C1c2ccccc2CC(NO)c2ccccc21,,CO,,[BH3-]C#N.[Na+],,test
+US20030022886A1,CCI.COc1cc(I)cc(OC)c1O>>CCOc1c(OC)cc(I)cc1OC,,CN(C)C=O,,Cl,[H-].[Na+],test
+US20070155744A1,O=C(NCc1ccc(F)cc1)c1nc(COC2CCCCO2)cc(OCc2ccccc2)c1OCc1ccccc1>>O=C(NCc1ccc(F)cc1)c1nc(CO)cc(OCc2ccccc2)c1OCc1ccccc1,,C1CCOC1,,Cl,[Na+].[OH-],test
+US20040077728A1,CCOC(=O)c1ccccc1C#C[C@H](C)CCCCO>>CCOC(=O)c1ccccc1CC[C@H](C)CCCCO,[Pd],CCO,,[H][H],,test
+US06518257B1,CC(C)C(O)(c1ccc(-c2ccc(F)cc2)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(C)C(O)(c1ccc(-c2ccc(F)cc2)cc1)c1c[nH]cn1,,CO,,Cl,c1ccncc1,test
+US20090124596A1,C1CNCCOC1.CC(C)(C)OC(=O)N[C@H]1CC[C@@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(C=O)cc4)c3)c2=O)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(CN5CCCOCC5)cc4)c3)c2=O)CC1,,ClCCCl,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US20130102776A1,COC(=O)c1c(OC)ccc2c1OCC2=O.O=Cc1n[nH]c2ccccc12>>COC(=O)c1c(OC)ccc2c1O/C(=C\c1n[nH]c3ccccc13)C2=O,C1CCNCC1,CO,,,,test
+US20110294812A1,CC(C)(C)[Si](C)(C)Cl.CC(C)(C)c1cc(N)n(-c2ccc(CO)cc2)n1>>CC(C)(C)c1cc(N)n(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2)n1,,CN(C)C=O,O,c1c[nH]cn1,,test
+US20090093462A1,Nc1ccc(I)cc1Cl.O=C(O)c1ccncc1F>>O=C(O)c1ccncc1Nc1ccc(I)cc1Cl,,C1CCOC1,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
+US04025524,ClCCN1CC2CC3CC(C2)CC1C3.N#CC(c1ccccc1)c1ccccc1>>N#CC(CCN1CC2CC3CC(C2)CC1C3)(c1ccccc1)c1ccccc1,,Cc1ccccc1,O,Cl,[H-].[Na+],test
+US20100261698A1,CC(C)(C)OC(=O)n1c(-c2cncc(OS(=O)(=O)N3CCCC3)c2)cc2ccc(Cl)cc21>>O=S(=O)(Oc1cncc(-c2cc3ccc(Cl)cc3[nH]2)c1)N1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
+US20030004181A1,COC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccn1.O=C(Cl)c1ccccc1>>COC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)NC(=O)c3ccccc3)cc1)n2C)c1ccccn1,,CO,ClCCl,Cl,,test
+US20030158245A1,CCOc1sc(C(=O)O)c2c1-c1c(cnn1C)CC2.N>>CCOc1sc(C(N)=O)c2c1-c1c(cnn1C)CC2,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
+US20130188270A1,CCCCC(CC)Cn1c2ccccc2c2cc(C(=O)c3ccc(F)cc3)c3ccccc3c21.Cc1cc(C)c(C(=O)Cl)c(C)c1>>CCCCC(CC)Cn1c2ccc(C(=O)c3c(C)cc(C)cc3C)cc2c2cc(C(=O)c3ccc(F)cc3)c3ccccc3c21,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
+US20120226036A1,CC(C)(C)OC(=O)CN(C(=O)OC(C)(C)C)c1cccc(C(NCc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccccn2)n1>>O=C(O)CNc1cccc(C(NCc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccccn2)n1,,ClCCl,,C1COCCO1,Cl,test
+US20100004128A1,CCOC(=O)C(F)(F)Cl.CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1O>>CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1OC(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20070082913A1,COC(=O)c1ccc(Cl)nc1N.[Li]O>>Nc1nc(Cl)ccc1C(=O)[O-].[Li+],,CO,O,,,test
+US20090082597A1,CNCCC(O)c1ccccc1.O=C(O)[C@@H](O)c1ccccc1>>CNCC[C@@H](O)c1ccccc1.O=C(O)[C@@H](O)c1ccccc1,,CCOC(C)=O,,,,test
+US20090306066A1,Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CCN(C)[C@H](C)C2)n1>>Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(O)C=O)c(F)c(N2CCN(C)[C@H](C)C2)n1,,CO,,,,test
+US20050143422A1,CCOC(=O)c1oc2ccc(Cl)c(O)c2c1C.CI>>CCOC(=O)c1oc2ccc(Cl)c(OC)c2c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20090093472A1,Cc1noc([C@H]2CCCN2C(=O)OCc2ccccc2)c1Cc1ccc(Cl)cc1>>Cc1noc([C@H]2CCCN2)c1Cc1ccc(Cl)cc1,,ClCCl,,C[Si](C)(C)I,,test
+US20120190701A1,COCCCc1cc(CCCOC)c(Cl)c(C(=O)OC)c1>>COCCCc1cc(CO)c(Cl)c(CCCOC)c1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
+US20090318518A1,FC(F)(F)c1ccc(CBr)cc1.Fc1cc(Br)c2[nH]ccc2c1>>Fc1cc(Br)c2c(ccn2Cc2ccc(C(F)(F)F)cc2)c1,,CN(C)C=O,,[H-].[Na+],,test
+US20150031685A1,COC(=O)Cc1cccc(N)c1.O=C(Cl)C=Cc1ccccc1>>COC(=O)Cc1cccc(NC(=O)/C=C/c2ccccc2)c1,,ClCCl,c1ccncc1,,,test
+US20100261727A1,Clc1ccnc(Cl)n1.OCCF>>FCCOc1ccnc(Cl)n1,,O,,C1CCOC1,[H-].[Na+],test
+US06544984B1,CC#CCO.COC(=O)C1CN(C(=O)c2ccccc2)c2ccccc2CN1S(=O)(=O)c1ccc(O)cc1>>CC#CCOc1ccc(S(=O)(=O)N2Cc3ccccc3N(C(=O)c3ccccc3)CC2C(=O)OC)cc1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
+US05037827,ClCc1ccccn1.O=C1CNC(=O)N1>>O=C1CNC(=O)N1Cc1ccccn1,,CN(C)C=O,,,,test
+US20060046977A1,C[Si](C)(C)C#Cc1ccccc1.O=c1c(I)c(OCc2ccccc2)ccn1Cc1ccccc1>>C[Si](C)(C)c1oc2c(c1-c1ccccc1)c(=O)ccn2Cc1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,CCN(CC)CC,,test
+US05948792,CC(C)(C)[C@H]1OC(=O)[C@](c2ccccc2)([C@H]2CCC(=O)C2)O1>>O=C(O)[C@](O)(c1ccccc1)[C@H]1CCC(O)C1,,CCOCC,CO,[BH4-].[Na+],,test
+US20060100230A1,CCOC(=O)COc1ccc(S(=O)(=O)Cl)cc1C.Cc1cc(Br)cc2c1NC(C)C2C>>CCOC(=O)COc1ccc(S(=O)(=O)N2c3c(C)cc(Br)cc3C(C)C2C)cc1C,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
+US20050080124A1,CCN(C=CC(=O)c1cc(NC(=O)Nc2ccc(F)cc2F)ccc1OC)CC.NN>>COc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1-c1ccn[nH]1,,CC(=O)O,CO,,,test
+US20130123438A1,C=C(C)C(=O)OCCCCCCCCO.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>C=C(C)C(=O)OCCCCCCCCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,ClCCl,,Cl,c1ccncc1,test
+US20090181942A1,CCOC(=O)[C@H]1CCCN(C(=O)C[C@@H]2O[C@@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c2nnc3C(F)(F)Cl)C1>>COc1cccc([C@@H]2O[C@@H](CC(=O)N3CCC[C@H](C(=O)O)C3)c3nnc(C(F)(F)Cl)n3-c3ccc(Cl)cc32)c1OC,,C1COCCO1,CCOC(C)=O,Cl,,test
+US20070225318A1,CN(C)c1ccncc1.Nc1ccc2cn[nH]c2c1.O=c1c2ccnn2c(=O)c2ccnn12>>CCCC(C)C.O=C(Nc1ccc2cn[nH]c2c1)c1cc[nH]n1,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
+US20080039437A1,CCOC(=O)c1cc(C#N)c(=O)[nH]c1C(F)F.O=C(Cl)C(=O)Cl>>CCOC(=O)c1cc(C#N)c(Cl)nc1C(F)F,,ClCCl,,CN(C)C=O,,test
+US20110053905A1,COC(=O)c1c[nH]c(-c2cc(Nc3cccc([N+](=O)[O-])c3)ccn2)c1>>COC(=O)c1c[nH]c(-c2cc(Nc3cccc(N)c3)ccn2)c1,,CCO,CCOC(C)=O,,,test
+US20040102456A1,Br.CNC(C)C#N.O=C(Br)C(=O)Br>>Cc1c(Br)nc(Br)c(=O)n1C,CN(C)C=O,ClCCl,ClCCl,,,test
+US05668128,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CC(C)CCN>>CC(C)CCNC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
+US05807927,CN1C(=O)N(CCC(=O)O)C(C)(C)C1=O.COC(CN)OC>>COC(CNC(=O)CCN1C(=O)N(C)C(=O)C1(C)C)OC,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
+US20100331317A1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN3C(=O)c4ccccc4C3=O)ccc21>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN)ccc21,,CO,,NN,O,test
+US20110053162A1,CC(=O)N(/C=C/C=C/C1=C[NH+]2CCc3ccc(S(=O)(=O)[O-])c(c32)C1(C)C)c1ccccc1.CC1=C[NH+]2CCc3ccc(S(=O)(=O)[O-])c(c32)C1(C)CCCCCC(=O)O>>CC1(CCCCCC(=O)O)C(/C=C/C=C/C=C2/N3CCCc4ccc(S(=O)(=O)[O-])c(c43)C2(C)C)=C[NH+]2CCc3ccc(S(=O)(=O)O)c1c32,,CC(=O)OC(C)=O,,c1ccncc1,,test
+US20040077669A1,CC#CCOc1cc(Cl)ncn1.CCCNCCC>>CC#CCOc1cc(N(CCC)CCC)ncn1,,CCOC(C)=O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
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+US20100137302A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CN1CCCCC1CCCl>>CN1CCCCC1CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1,,CCN(CC)CC,,Cl,,test
+US20130220415A1,O=C1C=c2ccccc2=N1.O=C1Nc2cc(Br)ccc2C1=O>>O=C1Nc2ccccc2/C1=C1\C(=O)Nc2ccccc21,,CC(=O)O,,Cl,,test
+US20110077236A1,CC(C)CC(NC(=O)OC(C)(C)C)C(=O)CCl.Nc1cc(Cl)ccn1>>CC(C)C[C@H](NC(=O)OC(C)(C)C)c1cn2ccc(Cl)cc2n1,,CO,,,,test
+US04548932,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)COc2ccccc21.CCOC(=O)C(Br)CCCCCCCN1C(=O)c2ccccc2C1=O>>CCOC(=O)[C@@H](CCCCCCCN1C(=O)c2ccccc2C1=O)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O,,CCN(CC)CC,,CC#N,,test
+US20160120850A1,CC(=O)c1ccc(Br)c2ccccc12.CC1(C)COCCN1>>CC(c1ccc(Br)c2ccccc12)N1CCOCC1(C)C,CC(=O)O,ClCCl,,O=C([O-])O.[Na+],,test
+US04038328,Cc1cc(O)c(S(=O)(=O)O)cc1Cl.ClCl>>Cc1c(Cl)cc(S(=O)(=O)O)c(O)c1Cl,,O,O=S(=O)(O)O,,,test
+US20120232052A1,COC(=O)c1ccc2[nH]ccc2c1.COCCBr>>COCCn1ccc2cc(C(=O)OC)ccc21,,O,,[H-].[Na+],,test
+US04028393,CC(C)O.N#CCl.Oc1cccc(O)c1>>N#C[O-].Oc1cccc(O)c1,,CC(C)O,,CCN(CC)CC,,test
+US20080161314A1,C#Cc1ccccc1.CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(Br)nn1.CCN(C(C)C)C(C)C>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(C#Cc2ccccc2)nn1.N,[Cu]I,C1COCCO1,,[Na+].[OH-],,test
+US04377522,CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2cc(N)ccc21.ClCl>>CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2c1ccc(N)c2Cl,,CC(=O)O,,,,test
+US08506655B1,O=[N+]([O-])c1cccc(P(=O)(O)c2cccc([N+](=O)[O-])c2)c1>>Nc1cccc(P(=O)(O)c2cccc(N)c2)c1,[Pt],CO,,[H][H],,test
+US20080090856A1,CC(C)c1cc(NC(=O)Nc2cc(Oc3ccc([N+](=O)[O-])nc3)ccc2F)n(-c2ccc3ncccc3c2)n1>>CC(C)c1cc(NC(=O)Nc2cc(Oc3ccc(N)nc3)ccc2F)n(-c2ccc3ncccc3c2)n1,[Zn],CO,,[Cl-].[NH4+],,test
+US20060040949A1,COc1ccc2nccc(OCC3CCC(NC(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2nccc(OC[C@@H]3CC[C@@H](N)CC3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20090270350A1,COc1ccc(Cn2c(C)cc(OCc3ccccc3CN3C(=O)c4ccccc4C3=O)c(Cl)c2=O)cc1Cl>>COc1ccc(Cn2c(C)cc(OCc3ccccc3CN)c(Cl)c2=O)cc1Cl,,CO,,NN,O,test
+US05622954,CC(C)(CC=O)c1ccc(F)cc1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)C(O)CC(C)(C)c1ccc(F)cc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
+US20130345218A1,COC(=O)C1C2CCC(CC2)C1Nc1cc(-c2c[nH]c3ncc(F)cc23)c(C#N)cc1F>>N#Cc1cc(F)c(NC2C3CCC(CC3)C2C(=O)O)cc1-c1c[nH]c2ncc(F)cc12,,C1CCOC1,,[Na+].[OH-],,test
+US20130059853A1,COCOc1c(-c2ccc3c(c2)COC3=O)ccc(OC)c1OC(F)F>>COc1ccc(-c2ccc3c(c2)COC3=O)c(O)c1OC(F)F,,CO,,Cl,,test
+US20080269196A1,CC(C)(C)OC(=O)NCc1ccc(-c2nccc(NCC3CC3)n2)cc1>>NCc1ccc(-c2nccc(NCC3CC3)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20090005397A1,CCCOc1ccccc1C1(O)C(=O)Nc2ccc(Cl)cc21.N>>COc1ccccc1C1(N)C(=O)Nc2ccc(Cl)cc21,,ClCCl,,CCO,O,test
+US20120172351A1,COC(=O)C[C@@H]1COc2cc(N)ccc21.Cc1c(C=O)cccc1-n1c([C@H]2CCCO2)nc2cc(Cl)ccc21>>COC(=O)C[C@@H]1COc2cc(NCc3cccc(-n4c([C@H]5CCCO5)nc5cc(Cl)ccc54)c3C)ccc21,,CC#N,CC(=O)O,[Na+].[OH-],,test
+US04617316,BrBr.COc1cc([N+](=O)[O-])ccc1-c1cccs1>>COc1cc([N+](=O)[O-])ccc1-c1ccc(Br)s1,,C1COCCO1,CCOCC,O=S([O-])[O-].[Na+].[Na+],,test
+US04489091,CCCC(=O)C=[N+]=[N-].Cc1cc(C)c(S(=O)(=O)O)c(C)c1C>>CCCC(=O)COS(=O)(=O)c1c(C)cc(C)c(C)c1C,,CCOCC,,,,test
+US20080318960A1,NNC(=O)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12.O=Cc1ccccc1Br>>O=C(NC(C(=O)N/N=C/c1ccccc1Br)c1n[nH]c(=O)c2ccccc12)c1ccccc1,,CCO,,CC(=O)O,,test
+US20120277208A1,CC(C)(C)O.COC(=O)c1cc(Oc2cnc(C(=O)O)cn2)cc(OC(C)C)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)c1cc(Oc2cnc(NC(=O)OC(C)(C)C)cn2)cc(OC(C)C)c1,,O,,CCN(CC)CC,,test
+US20100210631A1,CC(C)(C)OC(=O)C(CN)c1cccc(O)c1.CCCCBr>>CCCCOc1cccc(C(CN)C(=O)OC(C)(C)C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
+US20130296290A1,CC(C)(C)OC(=O)NCCc1nnc([C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)o1.O=C(O)C(F)(F)F>>NCCc1nnc([C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)o1.O=C(O)C(F)(F)F,,ClCCl,,,,test
+US20120088748A1,CC(C)(C)OC(=O)N1CCOC(CO[Si](C)(C)C(C)(C)C)(c2ccc(Cl)c(Cl)c2)C(=O)C1>>CC(C)(C)OC(=O)N1CCOC(CO[Si](C)(C)C(C)(C)C)(c2ccc(Cl)c(Cl)c2)C(O)C1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
+US20120157609A1,C=C(C)C(=O)Cl.CC(C)C(=O)C(C)(C)C(=O)OCC(C)(C)CO>>C=C(C)C(=O)OCC(C)(C)COC(=O)C(C)(C)C(=O)C(C)C,CN(C)c1ccncc1,O,,CCN(CC)CC,ClCCl,test
+US20110118261A1,CS(=O)(=O)Cl.OC1CCN(c2ccc(Br)cn2)C1>>CS(=O)(=O)OC1CCN(c2ccc(Br)cn2)C1,,ClCCl,,CCN(CC)CC,,test
+US06114358,CCOC(=O)CCC(C)=O.CCOC(OCC)OCC>>CCOC(=O)CCC(C)(OCC)OCC,Cc1ccc(S(=O)(=O)O)cc1,,,CCO,,test
+US20130096136A1,O=C(Oc1ccc(O)c(NC(=S)Nc2ccc(Cl)cc2)c1)c1ccccc1>>O=C(Oc1ccc2oc(Nc3ccc(Cl)cc3)nc2c1)c1ccccc1,,CCOC(C)=O,O,ClCCCl,,test
+US20040058820A1,C[C@@H](O)[C@@H](Cc1ccc(Cl)cn1)c1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[C@H](N=[N+]=[N-])[C@@H](Cc1ccc(Cl)cn1)c1ccccc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
+US20130065861A1,CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCC(F)(F)P(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCC(F)(F)P(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC,,CC#N,,C1CCNCC1,,test
+US20090176823A1,COC(=O)NCc1ccc(Cl)c(CO)c1>>COC(=O)NCc1ccc(Cl)c(C=O)c1,O=[Mn]=O,CC#N,,,,test
+US20060293379A1,C=CC#N.O=Cc1cc(Cl)ccc1O>>N#CC1=Cc2cc(Cl)ccc2OC1,,CCOCC,,C1CN2CCN1CC2,,test
+US20060173050A1,CCOc1nc(N)cc(N)c1C#N.O=C(Cl)Cc1cccs1>>CCOc1nc(NC(=O)Cc2cccs2)cc(N)c1C#N,,c1ccncc1,,O,,test
+US20100112476A1,CN.NC(=O)[O-].O=C1CC(=O)C2=C(C=NOC2)N1>>CNC(=O)c1cccnc1N,,C1COCCO1,CCO,O=C=O,,test
+US20130345123A1,COC(=O)[C@H]1CCCCN1C(=O)[C@H](CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1.O=C(O)C(F)(F)F>>COC(=O)[C@H]1CCCCN1C(=O)[C@H](CN)NC(=O)OCc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
+US20120245345A1,COc1ccc2ncc(Cl)c(C#N)c2n1.OCc1ccccc1>>COc1ccc2ncc(OCc3ccccc3)c(C#N)c2n1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
+US20040220189A1,CNc1nccn2c(Br)cnc12>>CNc1nccn2ccnc12,[Pd],CO,,,,test
+US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)C1CCCC1>>CCOc1cc(C2NC(=O)NC(C3CCCC3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
+US20110178063A1,C1COCCN1.CCOC(=O)c1csc(C=O)n1>>CCOC(=O)c1csc(CN2CCOCC2)n1,,CO,ClCCl,O=C([O-])O.[Na+],,test
+US20050209291A1,Nc1ccc2nc(NC3CCN(Cc4ccccc4)CC3)sc2c1.O=C(N=C=S)c1ccccc1>>O=C(NC(=S)Nc1ccc2nc(NC3CCN(Cc4ccccc4)CC3)sc2c1)c1ccccc1,,C1CCOC1,,,,test
+US20130327251A1,CCCCCCCCCCCCCCCCCCOc1cc(CCSC#N)cc(OCCCCCCCCCCCCCCCCCC)c1>>CCCCCCCCCCCCCCCCCCOC1(OCCCCCCCCCCCCCCCCCC)C=CC=C(CCS)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
+US20150266848A1,CCC1(CC)O[C@@H](CCOC(=O)C(C)(C)C)[C@H](Cc2ccccc2)O1>>CCC1(CC)O[C@@H](CCO)[C@H](Cc2ccccc2)O1,,CCOC(C)=O,CO,C[O-].[Na+],,test
+US05344843,CCC(C)(C)C(=O)OCc1cccc(C)c1OCCOc1ccc([C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1>>CCC(C)(C)C(=O)OCc1cccc(C)c1OCCOc1ccc([C@H](N)C(=O)OCc2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US05840732,O=c1cc2n(c(=O)n1CCCCCl)CCCS2(=O)=O.Sc1cccc2nccn12>>O=c1cc2n(c(=O)n1CCCCSc1cccc3nccn13)CCCS2(=O)=O,,CN(C)C=O,O,[H-].[Na+],,test
+US20010025042A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2c(c1)CCN2>>COc1ccc2c(c1)CCN2C(=O)OC(C)(C)C,,C1CCOC1,,,,test
+US20050026973A1,CCOC(=O)C(C)(C)Oc1ccc(OCCn2c(=O)sc3cc(C(=NOC)c4ccccc4)ccc32)cc1>>CON=C(c1ccccc1)c1ccc2c(c1)sc(=O)n2CCOc1ccc(OC(C)(C)C(=O)O)cc1,,CCO,,Cl,[K+].[OH-],test
+US05834493,COc1ccc2[nH]cc(CC3=CCCNC3)c2c1.Fc1ccc(CCCCCl)cc1>>COc1ccc2[nH]cc(CC3=CCCN(CCCCc4ccc(F)cc4)C3)c2c1,,CN(C)C=O,,[I-].[K+],,test
+US20140349998A1,CCOC(=O)c1c[nH]c2ncnc(Cl)c12.C[Si](C)(C)CCOCCl>>CCOC(=O)c1cn(COCC[Si](C)(C)C)c2ncnc(Cl)c12,,CN(C)C=O,,[H-].[Na+],,test
+US20050250810A1,CC(=O)OC(C)=O.CC1=C(CN(C)C(=O)/C=C/c2ccc(N)nc2)Cc2ccccc21>>CC(=O)Nc1ccc(/C=C/C(=O)N(C)CC2=C(C)c3ccccc3C2)cn1,,C1CCOC1,,O=C([O-])O.[Na+],,test
+US20110212967A1,CNC(=O)c1ccc(-c2cnc(N)nn2)cc1C.O=CC(Cl)Cc1ccc2ncccc2c1>>CNC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1C,,CCO,,,,test
+US20160200704A1,CC(C)(C)OC(=O)n1cc(Cl)c2cc(CO)ccc21.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)n1cc(Cl)c2cc(CCl)ccc21,,ClCCl,,CCN(CC)CC,,test
+US04070464,CC(C)(C)c1cc(I)c(O)c(CN)c1.CN1CCC(=O)CC1>>CN1CCC2(CC1)NCc1cc(C(C)(C)C)cc(I)c1O2,,c1ccccc1,,CC(=O)O,,test
+US20150210699A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1.Cl>>Cl.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1CCCNC1,,C1COCCO1,CCOCC,,,test
+US20110201663A1,CCOC(=O)Cc1cc(F)c(N2C(=O)c3c(c(OCC)c4ccccc4c3OCC)C2O)c(F)c1>>CCOC(=O)Cc1cc(F)c(N2Cc3c(c(OCC)c4ccccc4c3OCC)C2=O)c(F)c1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
+US20110076292A1,COC(=O)c1cnc2c(c1)OCCc1nc(-c3ccnn3C(C)C)cn1-2>>CC(C)n1nccc1-c1cn2c(n1)CCOc1cc(C(=O)O)cnc1-2,,C1CCOC1,CO,Cl,[Li+].[OH-],test
+US20100286211A1,N#Cc1ccc(Br)cc1F.[N-]=[N+]=[N-]>>Fc1cc(Br)ccc1-c1nnn[nH]1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
+US05994378,CC(C)(C)c1csc(-c2cc3cc(O)ccc3o2)n1.CCCC(Oc1ccccc1CO)C(=O)OC(c1ccccc1)c1ccccc1>>CCCC(Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)C(=O)OC(c1ccccc1)c1ccccc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
+US20020193367A1,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2nc(COC3CCCCO3)co2)c1.CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C>>CCCN(C)c1cc2c(cc1C)NC(=O)CC(c1cccc(-c3nc(CO)co3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20110077240A1,COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cc1)C(C)=O.Cc1cc(N)no1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)on5)cc4F)c3s2)cc1)C(C)=O,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
+US04959381,Nc1c(Cl)cc(C(=O)CBr)cc1C(F)(F)F.c1ccc(CCOCCCCCNCc2ccccc2)cc1>>Nc1c(Cl)cc(C(O)CN(CCCCCOCCc2ccccc2)Cc2ccccc2)cc1C(F)(F)F,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
+US20100298343A1,CCOC(=O)C(Cc1ccccc1)c1c(SC(C)(C)C)c2cc(OC)ccc2n1C>>COc1ccc2c(c1)c(SC(C)(C)C)c(C(CO)Cc1ccccc1)n2C,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
+US04849419,CC(=O)Oc1ccc(C(=O)Cl)cc1.Fc1c(F)c(F)c(S)c(F)c1F>>CC(=O)Oc1ccc(C(=O)Sc2c(F)c(F)c(F)c(F)c2F)cc1,,ClCCl,,c1ccncc1,,test
+US20120122780A1,S=C=Nc1cccc2ccccc12.[N-]=[N+]=[N-]>>Sc1nnnn1-c1cccc2ccccc12,,CCO,,Cl,,test
+US20100016164A1,CC1(C)COC(=S)N(Cc2ccccc2NS(=O)(=O)C(F)(F)F)C1.COC(=O)Cl>>COC(=O)N(c1ccccc1CN1CC(C)(C)COC1=S)S(=O)(=O)C(F)(F)F,,CC#N,,O,O=C([O-])O.[Na+],test
+US20080207655A1,CC1(C)OCC(N)CO1.N=C(N)n1cccn1>>CC1(C)OCC(NC(=N)N)CO1,,C1CCOC1,,,,test
+US06262040B1,CCc1nn(C2CCCC2)c2cc(C(=O)Nc3c(Cl)cncc3Cl)ccc12.CI>>CCc1nn(C2CCCC2)c2cc(C(=O)N(C)c3c(Cl)cncc3Cl)ccc12,,CN(C)C=O,O,[Na],,test
+US20130150333A1,CCNc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CCN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1ccc([N+](=O)[O-])cc1,,c1ccncc1,,CN(C)c1ccccn1,,test
+US20060004108A1,CC1(C)C2CC[C@@]1(C)C(=O)CC2=O.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CC1(C)C2CC[C@@]1(C)C(=O)C(C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C2=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
+US06121308,Cc1cc(C)c2ccc(N)cc2n1.O=C1OC(=O)c2ccccc21>>Cc1cc(C)c2ccc(N3C(=O)c4ccccc4C3=O)cc2n1,,CC(=O)O,,,,test
+US20020016339A1,BrCc1ccccc1.OCc1cccnc1>>OCC1=CC=CN(Cc2ccccc2)C1.[Br-],,CCO,,,,test
+US20110053931A1,CN1CCN(CCCO)CC1.COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1O>>COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1OCCCN1CCN(C)CC1,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
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+US20030055265A1,CCOC(=O)/C(=C/c1ccc(OCc2ccccc2)cc1C)OCC>>CCOC(=O)C(Cc1ccc(O)cc1C)OCC,[Pd],CCO,,,,test
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+US20110087030A1,CC(C#N)C(O)(Cn1cncn1)c1cc(F)ccc1F.CC1(C)C2CC[C@]1(CS(=O)(=O)O)C(=O)C2>>CC1(C)C2CC[C@]1(CS(=O)(=O)[O-])C(=O)C2.C[C@@H](C#N)[C@](O)(Cn1cncn1)c1cc(F)ccc1F,,CC(C)=O,CO,,,test
+US20080019915A1,O=C(O)C1(c2ccc3occc3c2)CC1>>O=C(O)C1(c2ccc3c(c2)CCO3)CC1,O=[Pt]=O,CO,,,,test
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+US20060154899A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#CCCCCCCN1C(=O)SC[C@@H]1/C=C/C(O)Cc1ccccc1>>O=C1SC[C@H](/C=C/C(O)Cc2ccccc2)N1CCCCCCc1nnn[nH]1,,Cc1ccccc1,,CCOC(C)=O,,test
+US20140288123A1,COC(=O)c1ccc([C@H](C)Oc2cccc(Br)c2)cc1>>C[C@H](Oc1cccc(Br)c1)c1ccc(C(=O)O)cc1,,CO,O,[Li+].[OH-],,test
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+US05968954,CN(C1CCNCC1)C1Cc2ccccc2C1.Clc1ccnc2c1OCCO2>>CN(C1CCN(c2ccnc3c2OCCO3)CC1)C1Cc2ccccc2C1,,Cc1ccccc1,,c1ccncc1,,test
+US05298498,O=C(O)c1cc2ccccc2cc1C(=O)O>>OCc1cc2ccccc2cc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
+US20020019388A1,Cc1cc(N2C[C@H]3CN(C(=O)OCc4ccccc4)C[C@H]32)cnc1Cl>>Cc1cc(N2C[C@H]3CNC[C@H]32)cnc1Cl,,O=C(O)C(F)(F)F,,,,test
+US20090291917A1,IC1CCCC1.N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(O)c1>>N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(OC2CCCC2)c1,,O,,CN(C)C=O,[H-].[Na+],test
+US05006519,CC(C)(C)[Si](C)(C)Cl.OCc1cc(Br)cc2ccccc12>>CC(C)(C)[Si](C)(C)OCc1cc(Br)cc2ccccc12,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
+US20150182537A1,O=C1OCCC1Br.Oc1ccccc1>>O=C1OCCC1Oc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
+US04598087,CN[C@@H]1CCCC[C@H]1N1CCCC1.O=C(O)COc1ccc(Cl)cc1>>CN(C(=O)COc1ccc(Cl)cc1)[C@@H]1CCCC[C@H]1N1CCCC1,,ClCCl,,CCOCC,,test
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+US20080312226A1,Cn1ncc(Br)c1N.O=C(Cl)OCC(Cl)(Cl)Cl>>Cn1ncc(Br)c1NC(=O)OCC(Cl)(Cl)Cl,,C1CCOC1,,O,c1ccncc1,test
+US20100113502A1,C=CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(=O)C(C)(F)F)CC2>>CCCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(=O)C(C)(F)F)CC2,[Pd],CO,,,,test
+US20030236287A1,COCCOc1ccc([N+](=O)[O-])c(OC)c1.Cl>>COCCOc1ccc(N)c(OC)c1.Cl,[Pd],CO,,,,test
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+US20110118330A1,COC(=O)CC[C@H](O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OC>>CC(C)(C)[Si](O[C@H](CO)CCCO)(c1ccccc1)c1ccccc1,Cl,CCOCC,,CO,[BH4-].[Li+],test
+US20050171087A1,Nc1cc2c(cc1Cl)N1CCC[C@@H](NC(=O)C(F)(F)F)[C@H]1c1ccccc1O2.O=S(=O)(Cl)c1ccccc1>>O=C(N[C@@H]1CCCN2c3cc(Cl)c(NS(=O)(=O)c4ccccc4)cc3Oc3ccccc3[C@H]12)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
+US20130252953A1,Cc1cc(C)c2c(=O)[nH]sc2n1.O=C(CCl)N1CCOCC1>>Cc1cc(C)c2c(OCC(=O)N3CCOCC3)nsc2n1,,ClCCl,,CCN(CC)CC,,test
+US20150111866A1,C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1nc(N2CC(F)C2)ncc1B1OC(C)(C)C(C)(C)O1.Cc1cc(C(=O)OC(C)(C)C)ccc1-c1cnc(C)c(Cl)c1>>Cc1cc(C(=O)OC(C)(C)C)ccc1-c1cnc(C)c(-c2cnc(N3CC(F)C3)nc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)c1,Cl[Pd]Cl,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
+US20140024649A1,CC(C)(C)OC(=O)N1OC2C=CC1C2>>CC(C)(C)OC(=O)N[C@H]1CC[C@@H](O)C1,[Pd],CO,,,,test
+US20150336944A1,CC(C)(C)OC(=O)N(c1nccs1)S(=O)(=O)c1cc(Cl)c(Oc2cnc(Cl)cc2-c2cccnc2)cc1F.OB(O)c1cccc(F)c1>>O=S(=O)(Nc1nccs1)c1cc(Cl)c(Oc2cnc(-c3cccc(F)c3)cc2-c2cccnc2)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
+US20160046596A1,COc1cc(C=Nc2ccc(F)c(Cl)c2)c(O)cn1.C[Si](C)(C)C#N>>COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2cn1,,ClCCl,,,,test
+US20100239900A1,CCN(CC)CC.O=C(O)CNCC(=O)O>>CCN(CC)CC.O=C(O)CNCC(=O)O,,CS(C)=O,,,,test
+US20110003820A1,CC1=NCCn2c(C)ccc21>>Cc1ccc2n1CCNC2C,,CO,,[BH4-].[Na+],,test
+US05707994,CCOC(=O)[C@H](CNC(=O)CCNC(=O)c1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)NS(=O)(=O)c1ccccc1>>CCOC(=O)[C@H](CNC(=O)CCNC(=O)c1ccc(C(=N)N)cc1)NS(=O)(=O)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
+US04788185,CCC(Br)C(=O)OC(C)(C)C.CSCCOC(=O)/C(=N\O)c1csc(N)n1>>CCC(O/N=C(\C(=O)OCCSC)c1csc(N)n1)C(=O)OC(C)(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
+US20160168156A1,COc1ncc(F)cc1C#CCCN1C(=O)c2ccccc2C1=O>>COc1ncc(F)cc1C#CCCN,,CO,ClCCl,NN,,test
+US20160194290A1,C=CC(C(C)C)C(C)(N=C=O)c1ccc(CCC(C)(C)C)c(Cl)c1.CCOC(=O)CCN>>C=CC(C(C)C)C(C)(NC(=O)NCCC(=O)OCC)c1ccc(CCC(C)(C)C)c(Cl)c1,,C1COCCO1,,CCN(CC)CC,Cl,test
+US05719141,CN=C=O.Nc1cnc2ccccc2c1>>CNC(=O)Nc1cnc2ccccc2c1,,ClCCl,,,,test
+US05158971,C[Si](C)(C)N=C=O.ONCc1ccc(CCCCCC(F)(F)F)s1>>NC(=O)N(O)Cc1ccc(CCCCCC(F)(F)F)s1,,C1COCCO1,,Cl,,test
+US03960828,CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CSCc1ccccc1)C(=O)NCC(N)=O.NC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1ccc([N+](=O)[O-])cc1>>CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CSCc1ccccc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)NCC(N)=O,,CCOC(C)=O,,CN(C)C=O,,test
+US20080076763A1,CC(C)(C)OC(=O)N1CCOC(COC(=O)c2ccccc2)C1>>CC(C)(C)OC(=O)N1CCOC(CO)C1,,CO,,[Na+].[OH-],,test
+US04485113,CN(SC(C)(C)CCl)C(=O)Cl.ON=C1CSCCS1>>CN(SC(C)(C)CCl)C(=O)ON=C1CSCCS1,,C1COCCO1,O,CCN(CC)CC,,test
+US20090163524A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CCCO)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)NC(CCCO)c1ccc(Cl)cc1,,ClCCl,,,,test
+US20040053952A1,Cc1c(Cl)[nH]c(=O)n(Cc2ccc(C(=O)OC(C)(C)C)cc2)c1=O.S>>Cc1c(S)[nH]c(=O)n(Cc2ccc(C(=O)OC(C)(C)C)cc2)c1=O,,CN(C)C=O,,[Na],,test
+US20030139390A1,Nc1cc(Cl)c(Sc2ccc3ccccc3c2)c(Cl)c1.O=S(=O)(Cl)c1ccc(Cl)nc1>>O=S(=O)(Nc1cc(Cl)c(Sc2ccc3ccccc3c2)c(Cl)c1)c1ccc(Cl)nc1,,C1CCOC1,,c1ccncc1,,test
+US05972972,Nc1n[nH]c(SCc2cccc(Oc3ccc(F)cc3)c2)c1-c1ccccn1.O=S(=O)(Cl)c1c(Cl)cccc1Cl>>O=S(=O)(Nc1n[nH]c(SCc2cccc(Oc3ccc(F)cc3)c2)c1-c1ccccn1)c1c(Cl)cccc1Cl,,c1ccncc1,,O,,test
+US20150284411A1,Nc1cnc(Cl)cc1N.S=C(n1ccnc1)n1ccnc1>>S=c1[nH]c2cnc(Cl)cc2[nH]1,,CN(C)C=O,,CCN(CC)CC,,test
+US05157041,CC(C)CCN1CCC[C@]1(C(N)=O)C(=O)OCc1ccccc1>>CC(C)CCN1CCC[C@H]1C(N)=O,[Pd],CCO,,N#N,,test
+US20130281392A1,Nc1cc(Oc2ccc(C(F)(F)F)cc2Cl)c(Cl)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(Oc2ccc(C(F)(F)F)cc2Cl)cc1N,[Zn],CCO,,Cl,,test
+US06248740B1,O=C(n1ccnc1)n1ccnc1.OCCOc1ccc2ncnn2n1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=C(OCCOc1ccc2ncnn2n1)C1CN(C(c2ccccc2)c2ccccc2)CCN1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
+US20120220665A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCC(c1ccccc1)C(O)c1cccc2ccccc12>>CN(CC(c1ccccc1)C(O)c1cccc2ccccc12)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
+US20110172429A1,Nc1nnc(-c2ccco2)o1.O=C(Cl)c1cc(-c2ccccc2)nc2ccccc12>>O=C(Nc1nnc(-c2ccco2)o1)c1cc(-c2ccccc2)nc2ccccc12,,CO,,c1ccncc1,,test
+US20050176706A1,CC(C)(CC1(C(F)(F)F)CO1)c1cc(-c2cncnc2)cc2c1OCC2.O=C1CCCc2[nH]ccc21>>CC(C)(CC(O)(Cn1ccc2c1CCCC2=O)C(F)(F)F)c1cc(-c2cncnc2)cc2c1OCC2,,CCO,,C,C[O-].[Na+],test
+US20050096380A1,CC(=O)OC(C)=O.COc1c(C(C)O)cc2c(c1Br)C(C)(C)CCC2>>COc1c(C(C)OC(C)=O)cc2c(c1Br)C(C)(C)CCC2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
+US04621084,CC(=O)OCCBr.Cc1c(-c2ccc3sc(=O)[nH]c3c2)nc2ccccn12>>CC(=O)OCCn1c(=O)sc2ccc(-c3nc4ccccn4c3C)cc21,,CN(C)C=O,O,Cl,[H-].[Na+],test
+US20120035208A1,CS(=O)(=O)c1ccc(O)cc1.Cn1ncc2c(Cl)cc(-c3cccc4[nH]ncc34)nc21>>Cn1ncc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(-c3cccc4[nH]ncc34)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US04477464,O=C1Nc2ccccc2OCC1N1C(=O)c2ccccc2C1=O>>NC1COc2ccccc2NC1=O,,CCO,,NN,O,test
+US05025036,CCCc1c(OCCCCCC(=O)c2c(C)c(C)c(OC)c(OC)c2C)ccc(C(=O)O)c1O>>CCCc1c(OCCCCCC(=O)c2c(C)c(C)c(O)c(O)c2C)ccc(C(=O)O)c1O,,ClCCl,,BrB(Br)Br,,test
+US04690942,O=C(c1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(F)n1cncn1>>OC(c1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(F)n1cncn1,,CO,O,[BH4-].[Na+],,test
+US20080275064A1,Cc1ccc(-c2nc(N)cc(-c3nccs3)n2)o1.O=C(Cl)CCl>>Cc1ccc(-c2nc(NC(=O)CCl)cc(-c3nccs3)n2)o1,,c1ccncc1,,ClCCl,,test
+US20140005133A1,NC(=O)CCC(=O)NCl.ON=Cc1ccccn1>>N=C(Cl)c1ccccn1,,CN(C)C=O,,,,test
+US20010021719A1,Cc1c(-c2ccc(OCc3ccccc3)cc2)[nH]c2ccc(OCc3ccccc3)cc12.ClCCCOc1ccc(CBr)cc1>>Cc1c(-c2ccc(OCc3ccccc3)cc2)n(Cc2ccc(OCCCCl)cc2)c2ccc(OCc3ccccc3)cc12,,CN(C)C=O,,O,[H-].[Na+],test
+US06034239,C=CCc1c(O)ccc2[nH]cc(CCNC(=O)CC)c12>>C=CCc1c(O)ccc2c1C(CCNC(=O)CC)CN2,,CC(=O)O,,O,[BH3-]C#N.[Na+],test
+US04377522,CN1C(=O)C(C)(C)N=C(c2ccccc2F)c2cc(N)c(Cl)c(Cl)c21>>CN1C(=O)C(C)(C)N=C(c2ccccc2F)c2cc(N)cc(Cl)c21,,CCOCC,,,,test
+US20150274661A1,O=C(Nc1cccc(F)c1)c1cc2cc(C3CCN(Cc4ccccc4)C3)ccc2[nH]1>>O=C(Nc1cccc(F)c1)c1cc2cc(C3CCNC3)ccc2[nH]1,[Pd],CO,,,,test
+US20050113397A1,C1CNCCN1.Cc1c(-c2ccccc2)c(Cl)n2c(nc3ccccc32)c1C#N>>Cc1c(-c2ccccc2)c(N2CCNCC2)n2c(nc3ccccc32)c1C#N,,CS(C)=O,,CCN(CC)CC,O,test
+US20110190255A1,CCOC(=O)[C@H]1CCCN(C[C@@H](O)c2ccc(/C(N)=N/O)cc2)C1.O=C(F)c1noc(-c2ccccc2)c1C(F)(F)F>>CCOC(=O)[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1,,CC#N,CCOC(C)=O,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
+US20110224262A1,c1ccc(COCCn2ccc(-c3ccccc3)n2)cc1>>OCCc1cc(-c2ccccc2)n[nH]1,[Pd],C1CCOC1,,CC(=O)O,,test
+US20040082573A1,CCOC(=O)c1ncn2c1CN=C(c1ccccc1)c1cc(Br)ccc1-2>>O=C(O)c1ncn2c1CN=C(c1ccccc1)c1cc(Br)ccc1-2,,CCO,,[Na+].[OH-],,test
+US20130225552A1,CCOC([O-])[O-].Nc1cccnc1N[C@@H]1C[C@@H](Nc2nc3ccccc3s2)C1>>c1ccc2sc(N[C@@H]3C[C@@H](n4cnc5cccnc54)C3)nc2c1,,CC(=O)O,,,,test
+US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NCC3CCCN(C(=O)OC(C)(C)C)C3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCC3CCCNC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
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+US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc([C@@H](C)N4CCNCC4)cnc3F)nc(C)n2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc([C@@H](C)N4CCN(S(C)(=O)=O)CC4)cnc3F)nc(C)n2)cc1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
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+US04895842,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O.CC1CCC(N)CC1C>>CC1CCC(NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC(=O)OC(C)(C)C)CC1C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
+US20070078121A1,CCOC(=O)/C(C)=C/c1cccc(-n2nc(C(C)(C)C)cc2N)c1>>CCOC(=O)C(C)Cc1cccc(-n2nc(C(C)(C)C)cc2N)c1,[Pd],CO,,,,test
+US20130017194A1,COC(=O)Cc1ccccc1C#C[Si](C)(C)C>>C#Cc1ccccc1CC(=O)OC,,ClCCl,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
+US04022901,O=[N+]([O-])c1ccc(-c2nc(-c3ccco3)no2)cc1>>Nc1ccc(-c2nc(-c3ccco3)no2)cc1,[Pd],,,Cl,O=C([O-])[O-].[K+].[K+],test
+US20060128695A1,COc1cc2c(cc1OC)C(c1cccc(C#N)c1)=NCC(=O)N2.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COc1cc2c(cc1OC)C(c1cccc(C#N)c1)=NCC(=S)N2,,c1ccncc1,,[Cl-].[Na+],,test
+US20110237573A1,Brc1ccnnc1.CCOC(=O)Cc1ccc(B(O)O)cc1>>CCOC(=O)Cc1ccc(-c2ccnnc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
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+US20050197351A1,C1CCNCC1.COC(=O)C=Cc1ccccc1N=C=Nc1ccccc1>>COC(=O)CC1c2ccccc2N=C(N2CCCCC2)N1c1ccccc1,,c1ccccc1,,,,test
+US20150322002A1,CS(=O)(=O)Cl.OCc1cc(F)c(Br)cc1Cl>>CS(=O)OCc1cc(F)c(Br)cc1Cl,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
+US20050020605A1,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.Cc1nc2ccncc2cc1C(=O)O>>CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3cc4cnccc4nc3C)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
+US07541367B2,COC(=O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12>>O=C(O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12,,CO,,Cl,[Na+].[OH-],test
+US20090018122A1,CCOCc1nc2cnc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)N.CS(=O)(=O)OS(C)(=O)=O>>CCOCc1nc2cnc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
+US20060287342A1,Cc1ccccc1.O=c1c(Br)c(Cl)n(Cc2ccccc2)c(=O)n1Cc1ccccc1.OB(O)c1ccc(Cl)cc1>>O=c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n(Cc2ccccc2)c(=O)n1Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
+US20050038035A1,Cc1ccc(C(=O)Cl)c(-c2ccc(C(F)(F)F)cc2)c1.Nc1ccc(C(=O)NCCc2ccccn2)cc1>>Cc1ccc(C(=O)Nc2ccc(C(=O)NCCc3ccccn3)cc2)c(-c2ccc(C(F)(F)F)cc2)c1,,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
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+US20150329560A1,CC(C)[C@@H]1CSC(=S)N1C(=O)C[C@H](O)/C=C/CCSC(c1ccccc1)(c1ccccc1)c1ccccc1.C[Si](C)(C)CCOC(=O)CN(Cc1cccc(CN)n1)Cc1cccc2ccccc12>>C[Si](C)(C)CCOC(=O)CN(Cc1cccc(CNC(=O)C[C@H](O)/C=C/CCSC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)Cc1cccc2ccccc12,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
+US20100256127A1,NN1CCOCC1.O=C(O)c1ccc(OCc2c(-c3ccccn3)noc2CO)nc1>>O=C(NN1CCOCC1)c1ccc(OCc2c(-c3ccccn3)noc2CO)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
+US05234931,CN1C2CCC1CC(C(=O)c1ccccc1F)C2.NN>>CN1C2CCC1CC(c1n[nH]c3ccccc13)C2,,CCO,,O,,test
+US06369070B1,CCOC(=O)c1cccc(N)c1.Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Cl>>CCOC(=O)c1cccc(NC(=O)c2c(-c3c(F)cccc3Cl)noc2C)c1,,ClCCl,,CCN(CC)CC,,test
+US20090099172A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCN(CCCO)CC1>>CC(C)(C)OC(=O)N1CCN(CCCBr)CC1,,C1CCOC1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[Na+].[Na+],test
+US20120071460A1,COCC(=O)CC(=O)OC.NC(=NO)c1cc(F)ccc1F>>COCC(=O)Cc1nc(-c2cc(F)ccc2F)no1,,CC#N,Cc1ccccc1,ClCCl,O,test
+US20040006114A1,Nc1cccc(Br)c1.O=Cc1cccnc1>>Brc1cccc(NCc2cccnc2)c1,,CO,,[BH4-].[Na+],,test
+US20160016908A1,CC(=O)N1c2ccccc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1CO[Si](C)(C)C(C)(C)C>>CC(=O)N1c2ccccc2[C@H](N)[C@@H](C)[C@@H]1CO[Si](C)(C)C(C)(C)C,[Pd],CO,,,,test
+US04025528,CCOC(=O)c1ccc(O)cc1.Clc1nccs1>>CCOC(=O)c1ccc(Oc2nccs2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20160152616A1,C=C/C=C/CBr.Cc1cc2[nH]c(=O)c(=O)n3c2c(c1C)C(C)(C)CC3>>C=C/C=C/Cn1c(=O)c(=O)n2c3c(c(C)c(C)cc31)C(C)(C)CC2,,CN(C)C=O,,O,[H-].[Na+],test
+US04031069,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O.CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O.C[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)O,,CCN(CC)CC,CO,C(=NC1CCCCC1)=NC1CCCCC1,,test
+US04857507,CC(C)S.CCOC(=O)CBr>>CCOC(=O)CSC(C)C,,CCO,,[Na],,test
+US20090253687A1,CCOC(=O)C(F)(F)F.COc1cc(C(C)=O)cc2c1OCC(=O)N2>>COc1cc(C(=O)CC(=O)C(F)(F)F)cc2c1OCC(=O)N2,,CCOCC,,,,test
+US20030232848A1,CC(=O)OCCBr.COCN(c1[nH]nc(OC)c1-c1ccc2c(c1)OCO2)S(=O)(=O)CCc1ccccc1>>COCN(c1nn(CCOC(C)=O)c(OC)c1-c1ccc2c(c1)OCO2)S(=O)(=O)CCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
+US20100216788A1,COC(=O)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCNC(=O)OC(C)(C)C)c34)cc2Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(=O)O)c4)c(Cl)c3)c21,,C1CCOC1,,CO,[Na+].[OH-],test
+US20100063091A1,COCCCc1cc(CNC2CC2)cc(O[Si](C)(C)C(C)(C)C)c1.Cc1cc(Cl)c(OCCOc2ccc([C@H]3CCN(C(=O)OC(C)(C)C)C[C@@H]3C(=O)O)cc2)c(Cl)c1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(O[Si](C)(C)C(C)(C)C)c1,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
+US20040082607A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(Br)ccc2c1=O>>CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(Br)ccc2c1=O,CN(C)c1ccncc1,C1CCOC1,,O,,test
+US06329381B1,BrBr.Cc1ccc(Sc2nc(N)c3ncn(Cc4ccccc4)c3n2)cc1>>Cc1ccc(Sc2nc(N)c3nc(Br)n(Cc4ccccc4)c3n2)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
+US20070208062A1,C=CCOC[C@@H]1CC(c2ccc(Br)cn2)=NO1.CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C>>C=CCOC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
+US20110212937A1,CNc1cc(C(=O)N(C)OC)nc(Cl)n1.O=C1CCC(=O)N1Br>>CNc1nc(Cl)nc(C(=O)N(C)OC)c1Br,,CC#N,,,,test
+US20130109661A1,BrBr.COC(=O)c1ccc(-c2ccc(N)nn2)cc1>>COC(=O)c1ccc(-c2cc(Br)c(N)nn2)cc1,,CO,,O=C([O-])O.[Na+],,test
+US20070055067A1,CC1(C)O[C@H](c2ccc(S(C)(=O)=O)cc2)[C@@H](CF)N1C(=O)C(Cl)Cl>>CS(=O)(=O)c1ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
+US05932601,COc1cc(C=CC=O)ccc1OCc1coc(-c2ccccc2)n1.O=C1COC(=O)N1>>COc1cc(C=CC=C2OC(=O)NC2=O)ccc1OCc1coc(-c2ccccc2)n1,,CC(=O)O,,C1CCNCC1,,test
+US20070293516A1,CC(C)n1nc(I)c2c(N)ncnc21.OB(O)c1cncnc1>>CC(C)n1nc(-c2cncnc2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
+US20030078251A1,CCOC(=O)c1oc2ccc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)cc2c1C>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc4oc(C(=O)O)c(C)c4c3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
+US20130079341A1,CN.Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1cc2ncc(Cl)nc2s1>>CNc1cnc2cc(C(=O)Nc3cc(NC(=O)c4cccc(C(C)(C)C#N)c4)ccc3C)sc2n1,,CCC(C)O,,CO,,test
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+US20140206680A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1Nc1nc(Cl)c2c(c1F)CN(C(=O)OC(C)(C)C)C2=O.CCCC[Sn](CCCC)(CCCC)c1cc2c(s1)c(C)nn2C>>Cn1ncc2sc(-c3nc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)c(F)c4c3C(=O)N(C(=O)OC(C)(C)C)C4)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
+US20130085142A1,CCOC(=O)C1CNCCN1.FC(F)(F)c1cccc(Br)n1>>CCOC(=O)C1CN(c2cccc(C(F)(F)F)n2)CCN1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
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+US20160221972A1,COC(=O)c1ccc(C(=O)OC)c(OCCNC(=O)OC(C)(C)C)c1.O=C(O)C(F)(F)F>>COC(=O)c1ccc(C(=O)OC)c(OCCN)c1.O=C(O)C(F)(F)F,,CCOCC,CO,ClCCl,,test
+US20080221110A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CC2(O)Cn3c(=O)ccc4ccc(Br)c2c43)CC1.N#C[Cu]>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CC2(O)Cn3c(=O)ccc4ccc(C#N)c2c43)CC1,,CN(C)C=O,,,,test
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+US20050032829A1,CCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)N.CS(=O)(=O)Cl>>CCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
+US20050261294A1,N#CCCN.O=Cc1cccs1>>N#CCCNCc1cccs1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US04625047,C=C(C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl)C1CCCC1.CCOC(=O)CC(C)=O>>O=C(O)COc1ccc(C2=CC(=O)CCC2C2CCCC2)c(Cl)c1Cl,,CCO,,C[O-].[Na+],,test
+US20100234351A1,COC(=O)C1=Cc2c(OC)ncnc2N(Cc2ccc(OC)cc2)CC1>>COC(=O)C1=Cc2c(ncnc2OC)NCC1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
+US20080103123A1,CC(C)(C)OC(=O)N1CCC(OCc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1>>CS(=O)(=O)c1ccc(-c2ccc(COC3CCNCC3)cn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20070184024A1,CC(C)S(N)(=O)=O.COC(=O)C1=Cc2cc(OC)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1>>COC(=O)C1=Cc2cc(OC)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)C(C)C)cc3n2C1,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
+US20110142796A1,COc1ccc2c3cnc(N)nc3n(C3CCCC3)c2n1>>Nc1ncc2c3ccc(O)nc3n(C3CCCC3)c2n1,,Cl,,O=C([O-])O.[Na+],,test
+US20110086834A1,CNCCO.COC(=O)C1(c2ccc(Br)cc2[N+](=O)[O-])CO1>>COC(=O)C(O)(CN(C)CCO)c1ccc(Br)cc1[N+](=O)[O-],,C1CCOC1,,,,test
+US06391880B1,O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1.c1cc(C2CCN(CC3CCNCC3)CC2)ccn1>>O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCC(CN2CCC(c3ccncc3)CC2)CC1,,ClCCl,ClCCl,CCN(CC)CC,Cl,test
+US05530130,Cc1ccccc1C.O=S(=O)(Cl)c1ccccc1>>Cc1ccc(S(=O)(=O)c2ccccc2)cc1C,Cl[Fe](Cl)Cl,,,Cl,,test
+US20020133007A1,CCOC(=O)/C=C(\N)C(F)(F)F.Cc1c(Cl)cc(F)c(NC(=O)Oc2ccccc2)c1[N+](=O)[O-]>>Cc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c1[N+](=O)[O-],,CN(C)C=O,O,C1CCC2=NCCCN2CC1,Cl,test
+US20160052898A1,Cc1ccc([N+](=O)[O-])cc1N.O=C(Cl)CCl>>Cc1ccc([N+](=O)[O-])cc1NC(=O)CCl,,ClCCl,,c1ccncc1,,test
+US20100137299A1,COc1ccc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3c2ccc2ncsc32)cc1>>O=C1Nc2ccc3ncsc3c2C12COc1cc3c(cc12)OCCO3,,ClCCl,O=C(O)C(F)(F)F,O=S(=O)(O)C(F)(F)F,,test
+US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CSc4nncs4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CS(=O)c4nncs4)cc2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
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+US20160102058A1,OC(C1CCCCC1)C1CCC(F)(F)CC1>>O=C(C1CCCCC1)C1CCC(F)(F)CC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
+US20090197891A1,COc1ccc(C(=O)O)c(OC)c1OC.O=C(Cl)C(=O)Cl>>COc1ccc(C(=O)Cl)c(OC)c1OC,CN(C)C=O,Cc1ccccc1,,,,test
+US20070265309A1,CC(C)(C)OC(=O)N1CCC[C@H]1C=O.NCc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1CNCc1ccc(F)cc1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US20040198778A1,COC(=O)C(NS(=O)(=O)c1ccc(Cl)s1)C(CC(F)(F)F)CC(F)(F)F>>O=S(=O)(NC(CO)C(CC(F)(F)F)CC(F)(F)F)c1ccc(Cl)s1,,C1CCOC1,,[BH4-].[Li+],,test
+US20070037794A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(Cl)cnc2C(=O)O)cc1.CNc1ccccc1F>>CN(C(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1)c1ccccc1F,,CN1CCCC1=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
+US20050197328A1,C=CC1CCN(C(=O)OC(C)(C)C)CC1.CCn1c(-c2nonc2N)nc2cncc(Br)c21>>CCn1c(-c2nonc2N)nc2cncc(CCC3CCNCC3)c21,,C1CCOC1,ClCCl,B1C2CCCC1CCC2,[Na+].[OH-],test
+US07179823B1,CCOC(=O)CCc1c[nH]nc1OCC.ClCc1ccc(OC2CCN(c3ccccn3)CC2)cc1>>CCOC(=O)CCc1cn(Cc2ccc(OC3CCN(c4ccccn4)CC3)cc2)nc1OCC,,O,,CN(C)C=O,[H-].[Na+],test
+US20110144105A1,CCC(O)(CC)c1ccc(C(=CC2CCCC2)c2cc3cccnc3[nH]2)cc1>>CCC(O)(CC)c1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1,[Pd],CO,,,,test
+US03998955,CCCCc1cnc(CO)cc1OC.Cl>>CCCCc1cnc(CO)cc1OC.Cl,,CCOCC,CO,CC(C)=O,,test
+US06960607B2,CNN.COc1ccc(C(=O)c2ccc3cc(OC)ccc3c2)c(F)c1>>COc1ccc2cc(-c3nn(C)c4cc(OC)ccc34)ccc2c1,CN(C)c1ccncc1,O,,c1ccncc1,,test
+US20160207893A1,CC(C)(C)OC(=O)NCCS.CCOC(=O)c1nc(OC)ncc1I>>CCOC(=O)c1nc(OC)ncc1SCCNC(=O)OC(C)(C)C,[Cu]I,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
+US20140005178A1,CCOC(=O)c1cc(C)ccc1Nc1cnc2ccccc2c1>>Cc1ccc(Nc2cnc3c(c2)CCCC3)c(C(=O)O)c1,O=[Pt]=O,O=C(O)C(F)(F)F,,,,test
+US04299834,CCOc1cc(SC)ccc1C(=O)O.Cl.Nc1cncnc1N>>CCOc1cc(SC)ccc1-c1nc2ncncc2[nH]1.Cl,,O=P(Cl)(Cl)Cl,,,,test
+US20150274750A1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)CNc1ncnc(Cl)c1[N+](=O)[O-]>>CCOC(=O)CNc1ncnc(N2CCN(C(=O)OC(C)(C)C)CC2)c1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
+US20080167286A1,N#Cc1cccc(C(N)=NO)c1.O=C(Cl)c1ccc(F)nc1>>N#Cc1cccc(-c2noc(-c3ccc(F)nc3)n2)c1,,c1ccncc1,,,,test
+US20160108047A1,NC1=COC1.[C-]#[N+]/C(=C\N(C)C)C(=O)OCC>>CCOC(=O)c1cn(C2COC2)cn1,,CCCCO,,,,test
+US20040186151A1,C/C=C\CBr.CC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)c2nc(-c3ccc(Cl)cc3Cl)c[nH]2)CC1>>C/C=C\Cn1cc(-c2ccc(Cl)cc2Cl)nc1[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CC[C@@H](CC)CC1,,CCOCC,,,,test
+US20090209524A1,CCCCCNc1nc(N)nc(C)c1CCCNCc1cccc(CC(=O)OC)c1.Cn1cnc(S(=O)(=O)Cl)c1>>CCCCCNc1nc(N)nc(C)c1CCCN(Cc1cccc(CC(=O)OC)c1)S(=O)(=O)c1cn(C)cn1,,ClCCl,,,,test
+US20020013310A1,Br.OCc1ccc2c(Cl)ccnc2c1>>Clc1ccnc2cc(CBr)ccc12,,O,,CCOC(C)=O,O=C([O-])O.[Na+],test
+US20090227602A1,CC(C)c1nc(-c2ccc(F)cc2)c(-c2ccnc(Nc3ccccc3)n2)n1/C=C/C=O.CCOC(=O)CC(C)=O>>CCOC(=O)CC(=O)CC(O)C=Cn1c(C(C)C)nc(-c2ccc(F)cc2)c1-c1ccnc(Nc2ccccc2)n1,,C1CCOC1,,[Li]CCCC,[H-].[Na+],test
+US04870096,COC(=O)CCc1ccc2[nH]cc(CCN(C)C)c2c1>>CN(C)CCc1c[nH]c2ccc(CCC(=O)O)cc12,,CO,,O,[Li+].[OH-],test
+US20050176786A1,Nc1cc(-c2cccc(Cl)c2)n[nH]1.O=C1CCC(=O)N1Br>>Nc1[nH]nc(-c2cccc(Cl)c2)c1Br,,C1CCOC1,,,,test
+US20050227983A1,COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl.O=Cc1ccc(O)cc1>>COc1ccc(Nc2nc(NC3CCCCCC3)nc(Oc3ccc(C=O)cc3)n2)cc1Cl,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
+US20110003786A1,CC(=O)Nc1nc2c(s1)-c1nc(CC3CC3)sc1CC2>>Nc1nc2c(s1)-c1nc(CC3CC3)sc1CC2,,CCO,,Cl,,test
+US04990511,NCCN1CCCCC1.O=C(O)Cc1ccc(OCc2ccccc2)cc1OCc1ccccc1>>O=C(Cc1ccc(OCc2ccccc2)cc1OCc1ccccc1)NCCN1CCCCC1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
+US20030232848A1,COc1nn(Cc2ccccc2)c(N)c1-c1ccc2c(c1)OCO2.O=S(=O)(Cl)/C=C/c1ccccc1>>COc1nn(Cc2ccccc2)c(NS(=O)(=O)/C=C/c2ccccc2)c1-c1ccc2c(c1)OCO2,,c1ccncc1,,CN(C)c1ccccn1,,test
+US20040157886A1,Nc1ccc2[nH]c(=O)[nH]c2c1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
+US20120058988A1,C1COCCN1.O=Cc1ccc(Br)cc1Cl>>Clc1cc(Br)ccc1CN1CCOCC1,,C1CCOC1,CCOC(C)=O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US06136831,CC(=O)N(C)C.Cc1ccc2ncsc2c1>>CC(=O)c1nc2ccc(C)cc2s1,,C1CCOC1,,O,[Li]CCCC,test
+US20140296253A1,ClCCCBr.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>ClCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
+US20150065519A1,O=S(=O)(Nc1ccc(-c2csc(Br)n2)c(Cl)c1)C(F)(F)F.OB(O)c1ccc2c(c1)CCO2>>O=S(=O)(Nc1ccc(-c2csc(-c3ccc4c(c3)CCO4)n2)c(Cl)c1)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
+US20040204386A1,COc1ccc(Cl)cc1-c1nc(Cl)cc(Cl)n1.N>>COc1ccc(Cl)cc1-c1nc(N)cc(Cl)n1,,C1CCOC1,,,,test
+US04785019,O=C(Cl)C(=O)Cl.O=C(O)c1cccc2ccccc12>>O=C(Cl)c1cccc2ccccc12,CN(C)C=O,ClCCl,,,,test
+US20100279872A1,COB(OC)OC.Cc1cc(C)cc(-c2ccccc2)c1.[Li]C(C)(C)C>>CCCC(C)C.Cc1cc(-c2ccccc2)cc(C)c1B(O)O,,C1CCOC1,,Cl,,test
+US04794110,CNC.O=C(CCl)c1cccn1C(c1ccccc1)c1ccccc1F>>CN(C)CC(=O)c1cccn1C(c1ccccc1)c1ccccc1F.Cl,,CO,,,,test
+US05153352,CC(C)(C)[Si](OCC1CC(N=[N+]=[N-])C1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCC1CC(N)C1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)(c1ccccc1)c1ccccc1,[Pd],CO,,O=C[O-].[NH4+],,test
+US04920120,C1CNCCN1.Cc1c(F)c(F)c(Cl)c2c1c(=O)c(C(=O)O)cn2C1CC1>>Cc1c(F)c(N2CCNCC2)c(Cl)c2c1c(=O)c(C(=O)O)cn2C1CC1,,CC#N,,,,test
+US20030187001A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1cc(Br)ccc1NC(=O)OC(C)(C)C>>COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)OC(C)(C)C,,CN(C)C=O,,ClCCl,CC(=O)[O-].[K+],test
+US20080194561A1,CN(C)/C=C/C(=O)c1ccc(C(=O)NCC(C)(C)CN(C)C)s1.COc1ccc(NC(=N)N)cc1>>COc1ccc(Nc2nccc(-c3ccc(C(=O)NCC(C)(C)CN(C)C)s3)n2)cc1,,CCO,,Cl,[Na],test
+US20150057240A1,BrCc1ccccc1.OC1C=CC(O)CC1>>OC1C=CC(OCc2ccccc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
+US20150203511A1,Cc1cc(-n2nc(C)c(C=O)c2C)ccc1OCc1c(C)cccc1-n1nnn(C)c1=O.NO>>Cc1cc(-n2nc(C)c(C=NO)c2C)ccc1OCc1c(C)cccc1-n1nnn(C)c1=O,,ClC(Cl)Cl,,Cl,c1ccncc1,test
+US20060069109A1,CI.O=Cc1[nH]cnc1-c1ccccc1>>Cn1cnc(-c2ccccc2)c1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
+US20090062342A1,COCCCc1cc(C=NC2CC2)c(Cl)cn1>>COCCCc1cc(CNC2CC2)c(Cl)cn1,,CO,,[BH4-].[Na+],,test
+US05346895,CC1(C)CC(C)(C)c2ccc(C#C[Si](C)(C)C)cc2O1>>C#Cc1ccc2c(c1)OC(C)(C)CC2(C)C,,CC(C)O,,[K+].[OH-],,test
+US20100174065A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CCC(=O)OC(C)(C)C)CC4)no2)cc1Cl.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CCC(=O)O)CC4)no2)cc1Cl.Cl,,C1COCCO1,Cl,,,test
+US20080269286A1,C=O.Fc1ccc(C2CCNCC2)c(F)c1>>CN1CCC(c2ccc(F)cc2F)CC1,,O,,O=CO,,test
+US20150045349A1,CC(C)C(C)n1cc(Br)c2[nH]nc(N)c2c1=O>>CC(C)[C@H](C)n1cc(Br)c2[nH]nc(N)c2c1=O,,CCCCCC,CCO,,,test
+US04469868,CC(C)[C@H](N)CO.Cc1nc(Cl)c2c(n1)c(C)nn2C>>Cc1nc(NC(CO)C(C)C)c2c(n1)c(C)nn2C,,CN(C)C=O,,CCN(CC)CC,,test
+US20100222355A1,CC(C)(C)OC(=O)N(CCCl)CCCl.N#CCc1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC(C#N)(c2cccc(F)c2)CC1,,CS(C)=O,ClCCl,[H-].[Na+],,test
+US04547494,CCOC(=O)/C(=N\OC1CCNC1=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(O)/C(=N\OC1CCNC1=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CO,,[Na+].[OH-],,test
+US20030191133A1,BrCCCBr.O=C1CCc2ccccc2N1>>O=C1CCc2ccccc2N1CCCBr,,CN(C)C=O,,[H-].[Na+],,test
+US20110053907A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Clc1nc(Cl)nc(N2CCOCC2)n1>>CC(C)(C)OC(=O)N1CCC(Oc2nc(Cl)nc(N3CCOCC3)n2)CC1,,C1CCOC1,,[H-].[Na+],,test
+US20150133451A1,CC1CCN(c2ccn(C)n2)C1=O.O=[N+]([O-])O>>CC1CCN(c2nn(C)cc2[N+](=O)[O-])C1=O,,CC(=O)OC(C)=O,,O=C([O-])O.[Na+],,test
+US20040058964A1,COC(=O)c1cccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1>>Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cccc(C(=O)O)c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
+US20110212945A1,O=P(Cl)(Cl)Cl.O=[N+]([O-])c1cnc(O)c(I)c1>>O=[N+]([O-])c1cnc(Cl)c(I)c1,,O,,ClP(Cl)(Cl)(Cl)Cl,,test
+US20100280019A1,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)nn1.NN1CCOCC1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NN2CCOCC2)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
+US20110135670A1,CCC[C@H](C)Oc1nc2nc(OC)nc-2c(N)[nH]1.ClCCCCBr>>CCC[C@H](C)Oc1nc(N)c2nc(OC)n(CCCCCl)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20080261969A1,CCOC(=O)c1[nH]ccc1N.O=C1CCCC(=O)C1.O=Cc1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1>>CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1,,CCO,,,,test
+US20110218188A1,COCC(=O)Cl.NC(=NO)c1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1>>COCC(=O)ON=C(N)c1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1,,CC(C)=O,,O=C([O-])O.[Na+],,test
+US20100240653A1,Brc1ccc(SCC2CCOCC2)cc1.O=S([O-])OO>>O=S(=O)(CC1CCOCC1)c1ccc(Br)cc1,,C1CCOC1,,O,,test
+US04200641,BrC(c1ccccc1)c1ccccc1.CCOC(=O)N1CCC(O)CC1>>CCOC(=O)N1CCC(OC(c2ccccc2)c2ccccc2)CC1,,O,,O=C([O-])[O-].[K+].[K+],,test
+US20110136780A1,COC(=O)c1cn(C(=O)OC(C)(C)C)c2nccc(CN[C@@H](C(=O)O)C3CCCC3)c12.NC1CCCC1>>COC(=O)c1cn(C(=O)OC(C)(C)C)c2nccc(CN[C@@H](C(=O)NC3CCCC3)C3CCCC3)c12,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
+US04182758,CCOP(=O)(CC(Br)CBr)OCC>>CCOP(=O)(/C=C\CBr)OCC,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
+US20040157804A1,CI.O=C1c2c(c(O)c3c(ncn3Cc3ccccc3)c2OC(c2ccccc2)c2ccccc2)C(=O)N1Cc1ccc(F)cc1>>COc1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncn(Cc4ccccc4)c13)C(=O)N(Cc1ccc(F)cc1)C2=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
+US20080085890A1,COC=C1C(=O)NC(=O)c2ccc(Br)cc21.NCCc1c[nH]c2ccccc12>>O=C1NC(=O)c2ccc(Br)cc2/C1=C/NCCc1c[nH]c2ccccc12,,CN(C)C=O,,,,test
+US06180718B2,CC(C)[Si](Cl)(Cl)C(C)C.COCOc1ccc(Br)cc1>>COCOc1ccc([Si](Cl)(C(C)C)C(C)C)cc1,,C1CCOC1,,CCOCC,[Li]CCCC,test
+US04126689,CCOC(=O)N1CCC(Nc2c(C)cccc2C)CC1.O=C(Cl)Cc1ccccc1>>CCOC(=O)N1CCC(N(C(=O)Cc2ccccc2)c2c(C)cccc2C)CC1,,c1ccccc1,,c1ccncc1,,test
+US20150353507A1,Clc1cccc(-c2nc(Cl)c3c(n2)CCC3)c1.Nc1ccc(CC(=O)O)cc1>>O=C(O)Cc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2CCC3)cc1,Cl,CN(C)C=O,,,,test
+US20070105943A1,N#Cc1ccc([N+](=O)[O-])s1.Oc1cccc(Br)c1>>N#Cc1ccc(Oc2cccc(Br)c2)s1,,CS(C)=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
+US20100240658A1,CC(=O)Cl.CC1CCCCN1c1ccc(C(=O)O)cc1N>>CC(=O)Nc1cc(C(=O)O)ccc1N1CCCCC1C,,ClCCl,,c1ccncc1,,test
+US04427817,C1CCCCC1.Cc1ccc(S(=O)(=O)O)cc1.O=CC1CC2C=CC1C2.OCC1CC2C=CC1C2.c1ccc2ncccc2c1>>C1=CC2CC1CC2COC(OCC1CC2C=CC1C2)C1CC2C=CC1C2,,C1CCCCC1,,,,test
+US20030100756A1,CSc1nc(Cl)c(C#N)c(Cl)n1.Nc1ccccc1>>CSc1nc(Cl)c(C#N)c(Nc2ccccc2)n1,,CCO,CCOCC,,,test
+US20090286778A1,O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(CCCc2cccc(N)c2)c1,[Pd],CN(C)C=O,,CC(=O)O,,test
+US20150018341A1,CCC(=C(c1ccc(O)cc1)c1ccc(OCCCl)cc1)c1ccc2oc(Cl)cc2c1.CNC>>CCC(=C(c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccc2oc(Cl)cc2c1,,CO,,,,test
+US20160244417A1,CI.O=C(O)[C@@H]1CCC(F)(F)C[C@H]1c1csc(-c2cncc(Cl)c2)n1>>COC(=O)[C@@H]1CCC(F)(F)C[C@H]1c1csc(-c2cncc(Cl)c2)n1,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
+US20020165241A1,Cc1cnc(NCC2CCNCC2)nc1.O=C(O)[C@@H]1C[C@H]1c1ccccc1>>Cc1cnc(NCC2CCN(C(=O)[C@@H]3C[C@H]3c3ccccc3)CC2)nc1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
+US05686469,CC(C)C[C@H](N)CN1CCC[C@H]1C(=O)NCCCCc1ccccc1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>CC(C)C[C@@H](CN1CCC[C@H]1C(=O)NCCCCc1ccccc1)NC(=O)C12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,,test
+US20050070441A1,CCc1c(Oc2ncc(C(F)(F)F)cc2Cl)n[nH]c1C.CN=C=O>>CCc1c(Oc2ncc(C(F)(F)F)cc2Cl)nn(C(=O)NC)c1C,,CCOC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
+US20080009486A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2cc(Cl)ccc2/C1=C/c1cc(Br)ccc1OCC(F)(F)F>>CC(C)(C)OC(=O)N1C(=O)/C(=C\c2cc(Br)ccc2OCC(F)(F)F)c2ccc(Cl)cc21,CN(C)c1ccncc1,ClCCl,,,,test
+US20140296067A1,N#CC1(c2ncc(C(F)(F)F)cc2Cl)CC1>>NCC1(c2ncc(C(F)(F)F)cc2Cl)CC1,[Ni],CO,,N,[H][H],test
+US20060041123A1,CCOC(=O)CS.COC(=O)c1nc(N)c(Br)cc1F>>CCOC(=O)CSc1cc(F)c(C(=O)OC)nc1N,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
+US04810699,Cc1ccc(Cl)c([N+](=O)[O-])c1.OCC(F)(F)F>>Cc1ccc(OCC(F)(F)F)c([N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
+US03940489,CC(C)(C)NCC(O)COc1ccc(Cl)cc1C#N>>CC(C)(C)NCC(O)COc1ccc(Cl)cc1CN,[Ni],CO,N,Cl,,test
+US20110147681A1,COC(=O)c1c2c(c3ccccc3c1O)OC(c1ccc(OC)cc1)(c1ccc(OC)cc1)C=C2>>C1=Cc2c(ccc3ccccc23)OC1,,C1CCOC1,,CCN(CC)CC,,test
+US20120238539A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(N2CCCC2=O)cc1>>O=C(Cl)c1ccc(N2CCCC2=O)cc1,CN(C)C=O,ClCCl,,,,test
+US20130296377A1,Cc1ccc(S(=O)(=O)n2ccc3c(COC4CCCCO4)c(C(O)CO)cc(C)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(COC4CCCCO4)c(C=O)cc(C)c32)cc1,,C1CCOC1,CCOC(C)=O,O,,test
+US20160002266A1,CCOC(=O)c1ccc(C2CCN(C)CC2)cc1>>CN1CCC(c2ccc(C(=O)O)cc2)CC1,,CCO,O,Cl,[Na+].[OH-],test
+US20060178381A1,CC(C)(C)OC(=O)N1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.Cc1csc(I)n1>>Cc1csc(-c2ccc3c(c2)CN(C(=O)OC(C)(C)C)C3)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US05459137,CC(=O)OC(C)=O.CC1Cc2cc3c(cc2C(c2ccc(N)cc2)=NN1)OCO3>>CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2CC1C)OCO3,,CCN(CC)CC,,ClC(Cl)Cl,,test
+US20140243310A1,COCOc1cnc(CO[Si](C)(C)C(C)(C)C)cc1F>>COCOc1cnc(CO)cc1F,,C1CCOC1,,[Cl-].[NH4+],,test
+US20120202785A1,COc1cccc(Nc2cc(F)ccc2[N+](=O)[O-])c1>>COc1cccc(Nc2cc(F)ccc2N)c1,,CCOC(C)=O,,,,test
+US20060135566A1,Cc1cccc(C(=O)C(Br)c2ccnc(N)c2)c1.NC(=S)c1ccc(F)cc1>>Cc1cccc(-c2nc(-c3ccc(F)cc3)sc2-c2ccnc(N)c2)c1,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
+US20080085886A1,O=C1c2ccccc2C(=O)N1O.OC1COC(c2ccccc2)OC1>>O=C1c2ccccc2C(=O)N1OC1COC(c2ccccc2)OC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
+US07163938B2,O=C(O)c1ccccc1NC(=O)N1CCC2(CC1)OCCO2>>O=c1oc(N2CCC3(CC2)OCCO3)nc2ccccc12,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
+US20030050298A1,CN(C)S(=O)(=O)c1c(Cl)ccc([N+](=O)[O-])c1O>>CN(C)S(=O)(=O)c1c(Cl)ccc(N)c1O,[Pd],CCOC(C)=O,,,,test
+US20070254906A1,COc1cc2c(cc1OC)[C@@H]1c3ccccc3CN[C@H]1CC2.Cl>>Cl.Oc1cc2c(cc1O)[C@@H]1c3ccccc3CN[C@H]1CC2,,Br,,,,test
+US20150274696A1,O=[N+]([O-])c1cc2nsnc2cc1F>>Nc1cc2nsnc2cc1F,[Fe],CCO,,O,[Cl-].[NH4+],test
+US05589478,Clc1cc(Cl)ncn1.OCCO>>OCCOc1cc(Cl)ncn1,,C1CCOC1,,[H-].[Na+],,test
+US20100310512A1,COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(N3CCN(c4ccc(-c5cnc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)n5COCC[Si](C)(C)C)cc4)CC3)cc2)n1COCC[Si](C)(C)C)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(N3CCN(c4ccc(-c5cnc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)[nH]5)cc4)CC3)cc2)[nH]1)C(C)C,,O=C(O)C(F)(F)F,,,,test
+US20040157886A1,Nc1ccc2c(c1)NC(=O)CO2.O=C(O)C(=O)N1CCC(Cc2ccccc2)CC1>>O=C1COc2ccc(NC(=O)C(=O)N3CCC(Cc4ccccc4)CC3)cc2N1,,CCOCC,,,,test
+US05977150,NNC(=O)c1ccc(C(F)(F)F)cc1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]nc(-c2ccc(C(F)(F)F)cc2)o1,,C1CCOC1,,CCN(CC)CC,,test
+US20160002221A1,CC(=O)c1ccc(Br)cc1>>CC(O)c1ccc(Br)cc1,,CCO,,Cl,[BH4-].[Na+],test
+US20160176858A1,COC(=O)C(NC(=O)[C@@H]1CC[C@@H](C)N(C(=O)c2ccccc2-n2nccn2)C1)C(=O)c1ccccc1>>C[C@@H]1CC[C@@H](c2nc(C(=O)O)c(-c3ccccc3)o2)CN1C(=O)c1ccccc1-n1nccn1,,C1CCOC1,O,[Li]O,,test
+US04034095,C=O.Cl.O=C(O)CC1CCNCC1Cc1ccccc1>>CN1CCC(CC(=O)O)C(Cc2ccccc2)C1.Cl,,O=CO,,Cl,N,test
+US20120277224A1,CC1(C)OC(=O)C(C(=O)c2ccc(S(C)(=O)=O)cc2)C(=O)O1.CCO>>CCOC(=O)CC(=O)c1ccc(S(C)(=O)=O)cc1,,CCO,,,,test
+US20140296231A1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NCC(O)Cc1ccc(F)cc1>>NCC(Cc1ccc(F)cc1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1,,CN(C)C=O,,Cl,[H-].[Na+],test
+US07652057B2,CC#CC(=O)OC.NNc1ccccn1>>Cc1cc(=O)[nH]n1-c1ccccn1,,CC(C)(C)O,O,CC(C)(C)[O-].[K+],,test
+US20130072523A1,C[Si](C)(C)C#Cc1ccc2cc(C#C[Si](C)(C)C)ccc2c1>>C#Cc1ccc2cc(C#C)ccc2c1,,CO,,ClCCl,O=C([O-])[O-].[K+].[K+],test
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+US20030195201A1,Nc1ccc2c(c1)OCCO2.Nc1ccnc(Cl)c1>>Nc1ccnc(Nc2ccc3c(c2)OCCO3)c1,[Cu]I,,,,,test
+US20140051676A1,CN.CN(c1ccccc1)c1nc(N)nc(-c2noc(-c3ccc(C(=O)O)s3)n2)n1>>CNC(=O)c1ccc(-c2nc(-c3nc(N)nc(N(C)c4ccccc4)n3)no2)s1,,CN(C)C=O,ClCCl,O=C(n1ccnc1)n1ccnc1,,test
+US04785019,N#CCN.O=C(Cl)c1cccc2ccccc12>>N#CCNC(=O)c1cccc2ccccc12,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,Cl,test
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+US20160229814A1,CCN1C(=O)C(c2ccccc2)Oc2cc([N+](=O)[O-])ccc21>>CCN1C(=O)C(c2ccccc2)Oc2cc(N)ccc21,[Pd],CO,,[H][H],,test
+US20040248854A1,COC(=O)CCCC#CCN1C(=O)CCC[C@@H]1CO>>COC(=O)CCCCCCN1C(=O)CCC[C@@H]1CO,[Pd],CO,,[H][H],,test
+US20060094714A1,CCOC(=O)CC(=O)c1cccnc1Nc1cccc(C(F)(F)F)c1>>O=c1cc(O)c2cccnc2n1-c1cccc(C(F)(F)F)c1,,Cc1ccccc1C,,,,test
+US20040152898A1,Nc1ccc(C(F)(C(F)(F)F)C(F)(F)Br)cc1Cl.O=C1CCC(=O)N1Br>>Nc1ccc(C(F)(C(F)(F)F)C(F)(F)Br)cc1Br,,CC#N,,,,test
+US03931239,CCCCC(=O)Cl.Cc1ccc2oc(C(=O)O)cc2c1C>>CCCCC(=O)c1cc2oc(C(=O)O)cc2c(C)c1C,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
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+US20140213586A1,CC(C)(C)OCCn1cc(C(=O)C(Cl)c2ccccc2)c2ccc(F)cc21.COc1cccc(N)c1>>COc1cccc(NC(C(=O)c2cn(CCOC(C)(C)C)c3cc(F)ccc23)c2ccccc2)c1,,CC#N,,,,test
+US20040171838A1,BrCc1ccccc1.COc1ccnc(C(=O)N[C@H]2COC(=O)[C@H](Cc3ccccc3)[C@@H](OC(=O)C(C)C)[C@H](C)OC2=O)c1O>>COc1ccnc(C(=O)N[C@H]2COC(=O)[C@H](Cc3ccccc3)[C@@H](OC(=O)C(C)C)[C@H](C)OC2=O)c1OCc1ccccc1,,CC(C)=O,ClCCl,[I-].[K+],O=C([O-])O.[Na+],test
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+US20160194290A1,C=CC(C(C)C)C(C)(NC(=O)NCCC(=O)OCC)c1ccc(CCC(C)(C)C)c(Cl)c1>>CCOC(=O)CCN1C=C(C(C)C)C(C)(c2ccc(CCC(C)(C)C)c(Cl)c2)NC1=O,,CO,,CSC,,test
+US20040224996A1,C=O.CCOCCc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1.CNC>>CCOCCc1nc(NS(=O)(=O)c2cccc(Cl)c2C)sc1CN(C)C,,CC(=O)O,,Cl,,test
+US20110218197A1,ClCCl.Cn1nc(C(C)(C)C)cc1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(Cl)c2[nH]1>>Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(Cl)c2[nH]1,,CO,,,,test
+US20060276433A1,COC(=O)ONC(=N)c1ccc([N+](=O)[O-])cc1>>O=c1[nH]c(-c2ccc([N+](=O)[O-])cc2)no1,,c1ccncc1,,Cl,,test
+US20150080364A1,CC(C)(C)OC(=O)N1CCNCC1.OC(c1ccc2c(c1)OC(F)(F)O2)c1ccc2c(c1)OC(F)(F)O2>>CC(C)(C)OC(=O)N1CCN(C(c2ccc3c(c2)OC(F)(F)O3)c2ccc3c(c2)OC(F)(F)O3)CC1,,ClCCl,,O=S(Cl)Cl,,test
+US20070244136A1,CNCCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.COC(=O)Cl>>COC(=O)N(C)CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12,,ClCCl,,CCN(C(C)C)C(C)C,,test
+US20040038239A1,CCCCc1ccc(Cc2ncccc2O)cc1.CI>>CCCCc1ccc(Cc2ncccc2OC)cc1,,CC(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
+US20090298815A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3cccc(NS(=O)(=O)c4c(F)cccc4F)c3F)c(-c3ccnc(N)n3)s2)CC1>>Nc1nccc(-c2sc(C3CCNCC3)nc2-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
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+US20090318421A1,C[C@H](CC#N)N(C(=O)[O-])C(C)(C)C.C[C@H](CCN)N(C(=O)[O-])C(C)(C)C>>C[C@H](CCN)NC(=O)OC(C)(C)C,[Ni],CCO,,N,,test
+US06018020,C=CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)CCC(=O)OC(C)(C)C)C(C)(C)C)C(OC)OC>>C=CCC(C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O)C(C)(C)C,O,ClCCl,O=C(O)C(F)(F)F,,,test
+US20010041700A1,C1COCCN1.COC(=O)[C@@H](CC(=O)O)CC1CCCCC1>>COC(=O)[C@@H](CC(=O)N1CCOCC1)CC1CCCCC1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
+US20110098324A1,CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccc(Cl)cc2Cl)c1=O.Nc1ccccc1C(F)(F)F>>O=C(O)CNC(=O)c1c(O)c(C(=O)Nc2ccccc2C(F)(F)F)c(O)n(Cc2ccc(Cl)cc2Cl)c1=O,,ClC(Cl)Cl,,,,test
+US05912353,CCc1nnc(N)s1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCc1nnc(NC(=O)C(F)(F)F)s1,,Cc1ccccc1,,CCN(CC)CC,O,test
+US20020077329A1,CCc1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCN(C(=O)[O-])S(=O)(=O)c2ccc(C)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1>>CCc1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCN(C(=O)O)S(=O)(=O)c2ccc(C)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,,,,test
+US20160009744A1,CC1(C)O[C@H]2[C@H](N)C[C@H](CO)[C@H]2O1.O=C(c1cc(Cc2cccc(Br)c2)cs1)c1cncnc1Cl>>CC1(C)O[C@H]2[C@H](Nc3ncncc3C(=O)c3cc(Cc4cccc(Br)c4)cs3)C[C@H](CO)[C@H]2O1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
+US20090018123A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(NC[C@H]1CN(c2cc(F)c(N3CCC(n4cnnn4)CC3)c(F)c2)C(=O)O1)C(F)F>>O=C1O[C@@H](CNC(=S)C(F)F)CN1c1cc(F)c(N2CCC(n3cnnn3)CC2)c(F)c1,,C1CCOC1,,,,test
+US03932433,CCOC(N)=S.COC(=O)C1CCCC(Br)C1=O>>COC(=O)C1CCCc2sc(=O)[nH]c21,,C1COCCO1,,,,test
+US20120316165A1,Cc1cc([C@@H]2CN(C(=O)OC(C)(C)C)CCO2)ccc1NC(=O)Nc1ccc(Cl)nc1>>Cc1cc([C@@H]2CNCCO2)ccc1NC(=O)Nc1ccc(Cl)nc1,,CC#N,O,O=C(O)C(F)(F)F,[Na+].[OH-],test
+US20160009740A1,CCCCCC(O)C=CB1OC(C)(C)C(C)(C)O1>>CCCCCC(O)/C=C/B(O)O,,CC(C)=O,O,,,test
+US20140275027A1,CC(C)(C)OC(=O)N1CCC(c2cc3c(Cl)c(F)cnc3[nH]2)CC1.COc1ccc(F)cc1B(O)O>>COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3CCN(C(=O)OC(C)(C)C)CC3)cc12,,C1CCOC1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
+US05147886,CS.O=C(CBr)c1ccc(C(F)(F)F)cc1>>CSCC(=O)c1ccc(C(F)(F)F)cc1,,CO,,O,[Na],test
+US20020161237A1,COC(=O)/C(=C/c1cnc2ccccc2c1)NC(=O)c1ccc(C(O)CCc2cccc(O)c2)cc1Cl>>O=C(O)/C(=C/c1cnc2ccccc2c1)NC(=O)c1ccc(C(O)CCc2cccc(O)c2)cc1Cl,,C1CCOC1,CO,[Na+].[OH-],,test
+US06352982B1,O=S(Cl)Cl.OCCCc1ccc(OCc2ccccc2)cc1>>ClCCCc1ccc(OCc2ccccc2)cc1,,Cc1ccccc1,,c1ccncc1,O=C([O-])O.[Na+],test
+US06979690B2,CCCCC(Br)C(=O)OCC.COc1nc(N)c(Cl)cc1C(=O)NCC1CCNCC1>>CCCCC(C(=O)OCC)N1CCC(CNC(=O)c2cc(Cl)c(N)nc2OC)CC1,,CN(C)C=O,O,CCN(CC)CC,[I-].[Na+],test
+US20050209291A1,Nc1nc2cc(NC(=S)NC(=O)c3ccccc3)ccc2s1>>NC(=S)Nc1ccc2sc(N)nc2c1,,CO,,C[O-].[Na+],,test
+US20040214888A1,COC(=O)c1cccc(-c2ccc(OC)c(CNC(=O)OC(C)(C)C)c2)c1>>COc1ccc(-c2cccc(CO)c2)cc1CNC(=O)OC(C)(C)C,,C1CCOC1,,Cl,[BH4-].[Li+],test
+US20090227640A1,Fc1ccc(OCC#Cc2ccc(C(F)(F)F)cc2)c(CBr)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(OCC#Cc2ccc(C(F)(F)F)cc2)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1.[Br-],,ClCCl,,,,test
+US20150057238A1,COS(=O)(=O)OC.O=C(O)C=CC(=O)c1ccc(Cl)c(Cl)c1>>COC(=O)C=CC(=O)c1ccc(Cl)c(Cl)c1,,CC(C)=O,,O=C([O-])O.[Na+],,test
+US20040267007A1,N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C[C@H](NC(=O)OCC(Cl)(Cl)Cl)[C@@H](O)[C@H](O)[C@H](O)CO,,O,,Cl,O=C([O-])O.[Na+],test
+US04868165,CSC(SC)SC.C[C@H](CCC=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>CSC(SC)(SC)C(O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,C1CCOC1,CCCCCC,[Li]CCCC,test
+US04029491,C=CCNCC=O.O=C=Nc1nc2ccc(Cl)cc2s1>>C=CCN(CC=O)C(=O)Nc1nc2ccc(Cl)cc2s1,,c1ccccc1,,,,test
+US20110152326A1,CC(C)(c1c(F)cc(O)cc1F)C(F)(F)F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(c1c(F)cc(OS(=O)(=O)C(F)(F)F)cc1F)C(F)(F)F,CN(C)c1ccncc1,CCOC(C)=O,,ClCCl,c1ccncc1,test
+US20100137394A1,CNC(=O)Nc1ccc(C2=NN(C(=O)Cc3cc(OC)c(OC)cc3Br)CC2)cc1.OB(O)c1ccccc1>>CNC(=O)Nc1ccc(C2=NN(C(=O)Cc3cc(OC)c(OC)cc3-c3ccccc3)CC2)cc1,,C1COCCO1,CO,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
+US20100317647A1,COC(=O)C1CCC(O)C1.CS(=O)(=O)Cl>>COC(=O)C1CCC(OS(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
+US20080269213A1,CC(C)C(=O)Cl.CN(C)Cc1ccc(C(N)Cc2cc(Cl)c3cccnc3c2OCc2ccccc2)o1>>CC(C)C(=O)NC(Cc1cc(Cl)c2cccnc2c1OCc1ccccc1)c1ccc(CN(C)C)o1,,C1CCOC1,,CCN(CC)CC,,test
+US20130059835A1,CCOc1c(C(C)=O)cc(Cl)c(C)c1I.CN(C)C(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1>>CCOc1c(C(C)=O)cc(Cl)c(C)c1-c1ccc(C(=O)N(C)C)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
+US20090111790A1,CC#N.Cn1ccc(NC(=O)c2cc(O)cc(OC3CCOCC3)c2)n1.O=C(c1ccc(Br)cn1)N1CCC1>>Cn1ccc(NC(=O)c2cc(OCc3ccccc3)cc(O[C@@H]3CCOC3)c2)n1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
+US20070265301A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1c2ccccc2CC1CO>>CC(C)(C)OC(=O)N1c2ccccc2CC1COCc1ccccc1,,C1CCOC1,CCOC(C)=O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
+US05202346,CC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(O)cc1>>CC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
+US06599917B1,CO[C@H]1CN(c2cccc(Cc3ccccc3)n2)C[C@H]1OCF.O=C1CCC(=O)N1I>>CO[C@H]1CN(c2ccc(I)c(Cc3ccccc3)n2)C[C@H]1OCF,,O,,CN(C)C=O,,test
+US05593969,CC(C)(C)[Si](C)(C)Cl.CCCCCCCCCCC[C@@H](O)CCO>>CCCCCCCCCCC[C@@H](O)CCO[Si](C)(C)C(C)(C)C,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
+US20150329523A1,COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Oc2ccccc2)cc1.Nc1ccc(Oc2ccnc(Cl)n2)c2ccccc12>>COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1,,CC(=O)OC(C)C,,CCN(CC)CC,,test
+US03979444,COC(=O)C1CC(C#N)(c2cccc3ccccc23)CCC1=O>>N#CC1(c2cccc3ccccc23)CCC(=O)CC1,,O,,CC(=O)O,O=S(=O)(O)O,test
+US20050032650A1,CCS.NS(=O)(=O)c1c(C(F)(F)F)nc2ccc(Cl)nn12>>CCSc1ccc2nc(C(F)(F)F)c(S(N)(=O)=O)n2n1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
+US20070249642A1,Clc1ccc(C23CNCC2C3)cc1.O=CCCn1cc(I)c(=O)n(C(=O)c2ccccc2)c1=O>>O=C(c1ccccc1)n1c(=O)c(I)cn(CCCN2CC3CC3(c3ccc(Cl)cc3)C2)c1=O,,ClCCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US20160176816A1,CCOC(=O)c1ccccc1-c1ccc(F)cc1>>O=C(O)c1ccccc1-c1ccc(F)cc1,,CCO,,[Na+].[OH-],,test
+US20070225267A1,CC(=O)OC(C)=O.CCc1ccccc1C[C@H](N)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C>>CCc1ccccc1C[C@H](NC(C)=O)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
+US20040242592A1,Nc1ccc(F)cc1F.O=C(CCl)NCc1ccccc1>>O=C(CNc1ccc(F)cc1F)NCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
+US20130267546A1,COCOCCCCCCCCCCc1cc(OC)nc(N(C)C)n1.O=C1CCC(=O)N1Br>>COCOCCCCCCCCCCc1nc(N(C)C)nc(OC)c1Br,,CC#N,,,,test
+US20110212937A1,C=C[Sn](CCCC)(CCCC)CCCC.CNc1nc(Cl)nc(C(=O)N(C)OC)c1Br>>C=Cc1c(NC)nc(Cl)nc1C(=O)N(C)OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
+US20100016319A1,CSc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2O)c1.Clc1ccnc(Cl)n1>>CSc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)c1,,CC(C)=O,,[Na+].[OH-],[Cl-].[NH4+],test
+US20120088748A1,CC(C)(C)OC(=O)N1CCOCC(=O)C1.Clc1ccc([Mg]Br)cc1Cl>>CC(C)(C)OC(=O)N1CCOCC(O)(c2ccc(Cl)c(Cl)c2)C1,,C1CCOC1,,O,,test
+US20030119787A1,CCOC(=O)C=C1CCP(c2ccccc2)C1(c1ccccc1)c1ccccc1.O=Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)C=Cc1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
+US20110281854A1,CN(C)C=O.C[C@@H]1CN(c2ccc3c(n2)NC(=O)CO3)[C@H](c2ccccc2)CO1>>C[C@@H]1CN(c2nc3c(cc2C#N)OCC(=O)N3)[C@H](c2ccccc2)CO1,,CN(C)C=O,,O=C1CCC(=O)N1Br,,test
+US09248117B2,CC(C)(C)OCl.COCCOCCOCCN1C(=O)NC(C)(C)C1=O>>COCCOCCOCCN1C(=O)N(Cl)C(C)(C)C1=O,,CO,,,,test
+US20110207702A1,COCCl.OCc1ccc(Sc2ccc(Cl)cc2)cc1Br>>COCOCc1ccc(Sc2ccc(Cl)cc2)cc1Br,,ClCCl,,CCN(C(C)C)C(C)C,,test
+US20150080549A1,CN(C)C(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C>>CN(C)C(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
+US20070051919A1,Fc1cccc(C=Cc2ccc3ccccc3c2)c1>>Fc1cccc(CCc2ccc3ccccc3c2)c1,[Pd],Cc1ccccc1,,,,test
+US06194410B1,CSc1nn2c(Cl)cc(C3CC3)nc2c1S(=O)(=O)c1ccccc1.N>>CSc1nn2c(N)cc(C3CC3)nc2c1S(=O)(=O)c1ccccc1,,CO,,,,test
+US20130096113A1,Cl.Nc1cc(I)ccn1.c1cn[nH]c1>>Cl.Nc1cc(-n2cccn2)ccn1,,CCO,CCOCC,C1COCCO1,,test
+US20060040968A1,N#CCc1cc(F)cc(F)c1>>NCCc1cc(F)cc(F)c1,,C1CCOC1,,,,test
+US08815901B2,CN1CCN(Cc2ccc(N)nc2)CC1.COc1cc(OC)c(Cl)c(-c2ccc(C(=O)O)c3ncccc23)c1Cl>>COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3ncccc23)c1Cl,,CO,ClCCl,,,test
+US20160137952A1,COC(=O)[C@H]1OC(O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.N#CC(Cl)(Cl)Cl>>COC(=O)[C@H]1OC(OC(=N)C(Cl)(Cl)Cl)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
+US20140114068A1,Cc1cc2c(cc1C)C1(N)C(=O)c3ccccc3C1(O)O2.O=C(O)c1ccc[nH]1>>Cc1cc2c(cc1C)C1(NC(=O)c3ccc[nH]3)C(=O)c3ccccc3C1(O)O2,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
+US20090325912A1,CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2.Cc1ccc(S(=O)(=O)O)cc1>>CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,O,,test
+US20060025395A1,C=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/C=C\C(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C>>C=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/C=C\C(=O)O)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C,,C1CCOC1,CCO,[K+].[OH-],,test
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+US20040063643A1,C=C(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)CC1(c2ccccn2)CCCCC1.O=O>>CC(=O)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)CC1(c2ccccn2)CCCCC1,,ClCCl,,,,test
+US20080027049A1,COc1cccc(OC)c1C(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCCC3>>COc1cccc(OC)c1C(=O)Nc1ccc2oc3c(c2c1)CCCCCC3,,CC(Cl)Cl,,,,test
+US20130203776A1,O=C(NCCCl)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)c[nH]c3=O)nc12>>O=C1NCCOc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc1c3n2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
+US20110152237A1,CCOC(=O)[C@@H]1CC2(CCC(F)(F)CC2)CN1.COC(=O)N[C@H](C(=O)O)C(C)C>>COC(=O)N[C@H](C(=O)N1CC2(CCC(F)(F)CC2)C[C@H]1C(=O)O)C(C)C,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
+US20120316194A1,Cn1ccc2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21.O=C1CCC(=O)N1Cl>>Cn1cc(Cl)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21,,CN(C)C=O,,,,test
+US20100029737A1,COC(=O)c1cc2c([nH]1)CC=C2c1ccc(-c2ccccc2)cc1>>COC(=O)c1cc2c([nH]1)CCC2c1ccc(-c2ccccc2)cc1,[Pd],,,,,test
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+US04680300,ClCCCCCCCCOc1ccc2ccccc2c1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCCCCCCCOc1ccc2ccccc2c1,,CN(C)C=O,,O,[K],test
+US20080249093A1,CCOC(=O)c1cnc(OC(C)C)c(I)c1>>CC(C)Oc1ncc(C(=O)O)cc1I,,CC(C)O,,[Na+].[OH-],,test
+US20100168418A1,COc1ccnc2cc(C(F)(F)F)ccc12.O=C(OO)c1cccc(Cl)c1>>COc1cc[n+]([O-])c2cc(C(F)(F)F)ccc12,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
+US05491144,COc1ccc(Nc2cc3c(cc2Nc2ccccc2)C(=O)NC3=O)cc1>>O=C1NC(=O)c2cc(Nc3ccc(O)cc3)c(Nc3ccccc3)cc21,,ClC(Cl)Cl,,BrB(Br)Br,,test
+US20110237628A1,CCOC(C)=O.CS(=O)(=O)OCC(c1c2c(nn1-c1ccc(Cl)cc1)CCC2)C1CCCCC1.O=C(NC1CCCCC1)C(c1c2c(nn1-c1ccc(Cl)cc1)CCC2)C1CCCCC1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>COC(=O)c1ccc(OCC(c2c3c(nn2-c2ccc(Cl)cc2)CCC3)C2CCCCC2)nc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
+US20100081692A1,COC(=O)CCc1ccccc1O.ClCCCBr>>COC(=O)CCc1ccccc1OCCCCl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
+US20140371203A1,Clc1ncnc2scc(-c3ccccc3)c12.OCC1CCNCC1>>OCC1(c2ncnc3scc(-c4ccccc4)c23)CCNCC1,,CCO,,CCN(CC)CC,,test
+US20080255111A1,CCOC(=O)C(=O)OCC.Cc1ccc(F)cc1[N+](=O)[O-]>>CCOC(=O)C(=O)Cc1ccc(F)cc1[N+](=O)[O-],,C1CCOC1,,O,[H-].[Na+],test
+US05283251,CC(C)Cc1ccc(C(Br)c2ccc(CC(C)C)cc2)cc1.Nc1cccc(C(=O)n2cc(CCCC(=O)O)c3cc(Cl)ccc32)c1>>CC(C)Cc1ccc(C(Nc2cccc(C(=O)n3cc(CCCC(=O)O)c4cc(Cl)ccc43)c2)c2ccc(CC(C)C)cc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
+US20130303524A1,NCc1ccco1.O=S(=O)(Cl)C(F)(F)F>>O=S(=O)(NCc1ccco1)C(F)(F)F,,c1ccncc1,,,,test
+US20130053565A1,CCCC#CCCC.Cc1ccc(S(=O)(=O)N2CC(=O)C2)cc1>>CCCC1=C(CCC)C(=O)CN(S(=O)(=O)c2ccc(C)cc2)C1,,Cc1ccccc1,,,,test
+US20020173518A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1ccc2nc[nH]c2c1>>Cc1ccc(S(=O)(=O)n2cnc3cc([N+](=O)[O-])ccc32)cc1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
+US05523476,COC(=O)c1cc(F)c(F)c(F)c1F>>O=C(O)c1cc(F)c(F)c(F)c1F,,O,,O=S(=O)(O)O,,test
+US04826834,CNC.Clc1ccc2ncnn2n1>>CN(C)c1ccc2ncnn2n1,,CCO,,,,test
+US20060094767A1,BrCCOC1CCCCO1.Oc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(OCCOC2CCCCO2)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
+US09212190B2,N#CC[C@H]1CCc2sc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c21.OO>>NC(=O)C[C@H]1CCc2sc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c21,,CO,ClCCl,,,test
+US05698526,C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC(=O)[C@]3(C)[C@H]1[C@@H]2C>>C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4C[C@H](O)[C@]3(C)[C@H]1[C@@H]2C,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
+US05185352,CCCCCCCCCCCCCCCCCCOc1coc(CO)cc1=O.CCCN>>CCCCCCCCCCCCCCCCCCOc1cn(CCC)c(CO)cc1=O,,CCO,O,,,test
+US20150018332A1,CCN(CC)S(F)(F)F.N#CC1(O)CN(C(c2ccccc2)c2ccccc2)C1>>N#CC1(F)CN(C(c2ccccc2)c2ccccc2)C1,,ClCCl,,O=C([O-])O.[Na+],,test
+US05380742,C=C(C)c1scc2c1CN(C(=O)OC(C)(C)C)C2>>CC(C)c1scc2c1CN(C(=O)OC(C)(C)C)C2,[Pd],CO,,O=C[O-].[NH4+],,test
+US20030097010A1,CCCCCCCCCCCCc1ccc(C(=O)c2cc(C(=O)O)c(C(=O)c3ccc(CCCCCCCCCCCC)cc3)cc2C(=O)O)cc1>>CCCCCCCCCCCCc1ccc(Cc2cc(C(=O)O)c(Cc3ccc(CCCCCCCCCCCC)cc3)cc2C(=O)O)cc1,[Pd],C1CCOC1,,[H][H],,test
+US20090214441A1,CCCCCCCC/C=C\CCCCCCCCN>>CCCCCCCCCCCCCCCCCCN,[Pd],CCO,,[H][H],,test
+US20150045560A1,CCCCC#Cc1ccc2c(NCCCCC)c(C#CCCCC)ccc2c1NCCCCC>>CCCCCn1c(CCCC)cc2ccc3c(ccc4cc(CCCC)n(CCCCC)c43)c21,,CS(C)=O,,[K+].[OH-],,test
+US20070078121A1,CC(C)(C)OC(=O)N1Cc2cc(-n3nc(C(C)(C)C)cc3NC(=O)Nc3cccc(Cl)c3Cl)ccc2C[C@H]1C(N)=O>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccc3c(c2)CN[C@H](C(N)=O)C3)n1,,C1COCCO1,Cl,,,test
+US04562189,BrCCCCOc1ccccc1.O=CN1CCNCC1>>c1ccc(OCCCCN2CCNCC2)cc1,,CC(C)O,,,,test
+US20070032478A1,CCn1cc(Cl)c(C(=O)O)n1.Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1>>CCn1cc(Cl)c(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4)c2)n1,,C1CCOC1,,O=S(Cl)Cl,,test
+US20150291595A1,CS(=O)(=O)Nc1cc(O)cc(O)c1.O=C(Cl)c1c(Cl)ncnc1Cl>>CS(=O)(=O)Nc1cc(O)cc(OC(=O)c2c(Cl)ncnc2Cl)c1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
+US05318966,CN=C=O.Cl.Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCCC1>>CNC(=O)Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCCC1.Cl,,CC#N,CCO,CCN(CC)CC,O=C([O-])O.[Na+],test
+US06277847B1,CC(C)N1Cc2c(cccc2[N+](=O)[O-])C1=O>>CC(C)N1Cc2c(N)cccc2C1=O,[Fe],CC(=O)O,,O,,test
+US20110034439A1,COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1C(=O)O.CS(=O)(=O)CCN>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1C(=O)NCCS(C)(=O)=O,,CCO,,CCN(CC)CC,Cl,test
+US20130338141A1,COC(=O)c1nc(C(CCC(C)(CO[Si](C)(C)C(C)(C)C)OC)N(C)C(=O)OC(C)(C)C)[nH]c(=O)c1O.Cc1cc(CN)ccc1F>>COC(C)(CO)CCC(c1nc(C(=O)NCc2ccc(F)c(C)c2)c(O)c(=O)[nH]1)N(C)C(=O)OC(C)(C)C,,CC(C)O,,,,test
+US20160145247A1,CC(C)(C)OC(=O)N[C@H](CO)c1cccc(-c2cc(COc3ccccc3CC(=O)O)cc(C(=O)N[C@H]3CCOc4ccccc43)c2)c1>>N[C@H](CO)c1cccc(-c2cc(COc3ccccc3CC(=O)O)cc(C(=O)N[C@H]3CCOc4ccccc43)c2)c1,,C1COCCO1,,Cl,,test
+US20160130268A1,CC(C)(C)OC(=O)Nc1ccc(CCOS(C)(=O)=O)nc1.COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3[nH]c2=O)c1>>COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCc3ccc(NC(=O)OC(C)(C)C)cn3)c2=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
+US20100035908A1,COC(=O)c1ccc(OC)c(OC)c1OCC(=O)OC(C)(C)C>>COC(=O)c1ccc(OC)c(OC)c1OCC(=O)O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
+US20080153852A1,COc1ccc(Br)c(C(O)C(F)(F)F)c1.Cc1cn[nH]c1>>COc1ccc(-n2cc(C)cn2)c(C(O)C(F)(F)F)c1,[Cu]I,CCOC(C)=O,Cc1ccccc1,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
+US20160068532A1,Brc1cc2[nH]ncc2nc1Br.C=C[Sn](CCCC)(CCCC)CCCC>>C=Cc1nc2cn[nH]c2cc1Br,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,,,test
+US20080119518A1,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COc1cccc(Oc2cccc(Br)n2)c1C=O>>CO/C=C/c1c(OC)cccc1Oc1cccc(Br)n1,,C1CCOC1,O,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
+US05716624,CC1(C)CCSc2ccc(C=C(Br)Br)cc21>>C#Cc1ccc2c(c1)C(C)(C)CCS2,,O,,C1CCOC1,[Li]CCCC,test
+US20100160340A1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(F)cn1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])nc2)CC1,,CC(=O)N(C)C,,O,CC(C)(C)[O-].[K+],test
+US20160272632A1,N#C/C=C1\CCCOC1.Nc1n[nH]c2ccnc(OCc3ccccc3)c12>>N#CCC1(n2nc(N)c3c(OCc4ccccc4)nccc32)CCCOC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
+US20060199960A1,CCOC(=O)c1nc(C)ccc1Br.Cn1nc(C2CC2)cc1N>>CCOC(=O)c1nc(C)ccc1Nc1cc(C2CC2)nn1C,[Pd],,,,,test
+US20100190825A1,CCO[C@@H]1CC[C@@H](N2CCC(N)CC2)CC1.N#Cc1cc(I)c(N)cc1Cl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCO[C@@H]1CC[C@@H](N2CCC(NC(=O)Nc3cc(Cl)c(C#N)cc3I)CC2)CC1,,C1COCCO1,ClCCl,,,test
+US20040082607A1,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(-c3nsc(=O)[nH]3)ccc2c1=O.Cl>>CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(-c3nsc(=O)[nH]3)ccc2c1=O.Cl,,C1CCOC1,CCOC(C)=O,,,test
+US04576933,CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OCc1ccccc1>>CCCCCCCCCCCCCCCCCCNC(=O)OCC(O)COP(=O)([O-])OCC[N+](C)(C)C,[Pd],CC(=O)O,,,,test
+US20060100237A1,CC(C)(C)OC(=O)N1C[C@@H]2CC[C@H](Oc3cc(-n4cccn4)ccc3-c3nn[nH]n3)C[C@H]2C[C@H]1C(=O)O.Cl>>Cl.O=C(O)C1CC2CC(Oc3cc(-n4cccn4)ccc3-c3nn[nH]n3)CCC2CN1,,CCOCC,ClCCl,,,test
+US06417009B1,CNC(=O)CC(C)CCCC(C)CCCC(C)CCCC(C)C>>CNCCC(C)CCCC(C)CCCC(C)CCCC(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
+US04465851,Cl.N=C(N)NC[C@@H]1CC[C@@H](C(=O)O)CC1.O=c1c(O)c(-c2ccccc2)oc2ccccc12>>Cl.N=C(N)NC[C@@H]1CC[C@@H](C(=O)Oc2cccc(-c3cc(=O)c4ccccc4o3)c2)CC1,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
+US05047554,CS(=O)(=O)c1ccc(C(=O)Cl)s1.NC(=O)N1C(=O)Cc2cc(Cl)ccc21>>CS(=O)(=O)c1ccc(C(=O)C2C(=O)N(C(N)=O)c3ccc(Cl)cc32)s1,CN(C)c1ccncc1,,,,,test
+US20030166644A1,CN(C(=O)Cl)c1ccccc1.COc1ccc(-c2ccn(O)n2)cc1>>COc1ccc(-c2ccn(OC(=O)N(C)c3ccccc3)n2)cc1,,CCCCCCC,CCOC(C)=O,,,test
+US20100113462A1,C#CCBr.CCOC(=O)C1(NC(=O)c2cccc(C)c2O)Cc2ccccc2C1>>C#CCOc1c(C)cccc1C(=O)NC1(C(=O)OCC)Cc2ccccc2C1,,CN(C)C=O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
+US04375508,BrCC#CCBr.CCn1c(C)nc2cc(Cl)c(Cl)cc21>>CCn1c(C)[n+](CC#CCBr)c2cc(Cl)c(Cl)cc21.[Br-],,CCOCC,,,,test
+US20050153959A1,C1CCNCC1.Cc1cc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ccc(C=O)cn2)cc2cn[nH]c12>>Cc1cc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ccc(CN3CCCCC3)cn2)cc2cn[nH]c12,C1CCNCC1,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
+US20100075948A1,CC(=O)OC(C)=O.CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCNCC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F.ClCCl>>CN1CCC(NC(=O)C2NC(CC(C)(C)C)C(C#N)(c3ccc(Cl)cc3F)C2c2cccc(Cl)c2F)CC1=C=O,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
+US20080119465A1,CC(C)(C)O.O=C(O)Cc1ccc(OCCNC(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)Cc1ccc(OCCNC(=O)OCc2ccccc2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,CCOC(=O)Cl,test
+US20150175623A1,CC(C)[Si](OCCN1CCN(CC(F)F)CC1)(C(C)C)C(C)C>>OCCN1CCN(CC(F)F)CC1,,C1CCOC1,,,,test
+US20130196993A1,CCC/C=C/C(=O)Cl.COc1cc(NCCN)c2ccccc2n1>>CCCC=C(CCNc1cc(OC)nc2ccccc12)C(N)=O,,ClCCl,,CCN(CC)CC,,test
+US20040044008A1,Brc1ccc(C2=CCNCC2)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=C(c2ccc(Br)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
+US06521395B1,CCCCCCCCCCCCS(=O)(=O)c1ccc(C(=O)OC)cc1>>CCCCCCCCCCCCS(=O)(=O)c1ccc(C(=O)O)cc1,,CO,O,Cl,[K+].[OH-],test
+US20130165464A1,COc1ccc(CNc2cc(-n3cc(-c4ccccc4Cl)c(-c4nccn4COCC[Si](C)(C)C)c3)c(C)cn2)c(OC)c1.O=C(Cl)C1CC1>>COc1ccc(CN(C(=O)C2CC2)c2cc(-n3cc(-c4ccccc4Cl)c(-c4nccn4COCC[Si](C)(C)C)c3)c(C)cn2)c(OC)c1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
+US20100216788A1,CC(C)(C)NC(=O)c1cccc(Cn2ccc3cc(N)ccc32)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>CC(C)(C)NC(=O)c1cccc(Cn2ccc3cc(Nc4ncnc5ccn(CCO)c45)ccc32)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
+US20130143863A1,CC1(C)c2ccc(F)cc2C(=O)N1c1cncc(CO)c1.O=S(Cl)Cl>>CC1(C)c2ccc(F)cc2C(=O)N1c1cncc(CCl)c1,,ClCCl,,,,test
+US20120010190A1,CCCCCCC.O/N=C(\CC(c1ccccc1)c1cccc(Br)c1)c1ccncc1>>CCC(CC(=NO)c1ccncc1)c1cccc(Br)c1,,CCCCCCC,,CC(C)O,,test
+US20060148806A1,CCOC(=O)CC(=O)c1cc(F)c(F)cc1F.COC1=NCCC1>>CCOC(=O)C(C(=O)c1cc(F)c(F)cc1F)=C1CCCN1,,CCN(CC)CC,,,,test
+US20160052923A1,CC(Cl)Br.N#CCc1ccccc1>>N#CC1(c2ccccc2)CC1,,C1CCOC1,CS(C)=O,[H-].[Na+],,test
+US20080227834A1,CCCCN.N#Cc1ccc(CBr)cc1F>>CCCCNCc1ccc(C#N)c(F)c1,,CN(C)C=O,,,,test
+US20140187596A1,CCCCCCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2cc(F)ccc2CCC(=O)OC)n1>>CCCCCCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2cc(F)ccc2CCC(=O)O)n1,,C1CCOC1,O,[Li+].[OH-],,test
+US20090247526A1,CCOC(=O)c1ccc(Cl)c(Oc2cc(NC(=S)NC(=O)c3ccccc3)ncc2Br)c1>>CCOC(=O)c1ccc(Cl)c(Oc2cc(NC(N)=S)ncc2Br)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
+US06613942B1,COc1cc(O)ccc1C=O.O=C(CBr)N[C@H]1CCN(Cc2ccccc2)C1>>COc1cc(OCC(=O)N[C@H]2CCN(Cc3ccccc3)C2)ccc1C=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
+US20130023541A1,CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccc(C=O)cc2)CC1.CCNCc1c(F)cccc1Cl>>CCN(Cc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1)Cc1c(F)cccc1Cl,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US05789440,Cc1ccc(S)c(C(C)C)c1.O=C1OC(CCc2ccccc2)(c2ccccc2)CC(O)=C1Br>>Cc1ccc(SC2=C(O)CC(CCc3ccccc3)(c3ccccc3)OC2=O)c(C(C)C)c1,,ClCCl,,C1CCNCC1,,test
+US20110082181A1,CS(N)(=O)=O.Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1[C@H](O)COCc1ccccc1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)c1[C@H](O)COCc1ccccc1,CN(C)c1ccncc1,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
+US20050165001A1,CC(C)(C)OC(=O)N1CCN(c2c(F)ccc(F)c2C#N)CC1.NCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2c(F)ccc(NCc3ccccc3)c2C#N)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20140275528A1,BrBr.Cn1c(=O)c2[nH]cnc2n(C)c1=O>>Cn1c(=O)c2[nH]c(Br)nc2n(C)c1=O,,CC(=O)O,O,,,test
+US04220647,COc1ccc(CCNC(=O)CNc2ccc(C)cc2)cc1OC.O=C(Cl)OCc1ccccc1>>COc1ccc(CCNC(=O)CN(C(=O)OCc2ccccc2)c2ccc(C)cc2)cc1OC,,ClC(Cl)Cl,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
+US20160257668A1,C1COCCN1.C[Si](C)(C)CCOCn1ncc2cc(NC(=O)c3ncc(F)cc3-c3ccc(F)cc3)ccc21>>C[Si](C)(C)CCOCn1ncc2cc(NC(=O)c3ncc(N4CCOCC4)cc3-c3ccc(F)cc3)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US05344843,COC(=O)C(=O)c1ccc(O)cc1.ClCc1cc2ccccc2o1>>O=C(O)C(=O)c1ccc(OCc2cc3ccccc3o2)cc1,,CN(C)C=O,O,[H-].[Na+],,test
+US05373015,CCc1cc2[nH]c(=O)ccc2c(CC)n1>>CCc1cc2c(c(CC)n1)CCC(=O)N2,[Pd],CCO,,,,test
+US20070135467A1,NC(=S)N[C@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1.O=C1CCCC1>>Fc1cc(OC(F)(F)C(F)F)cc([C@@](Cc2ccccc2)(Nc2nc3c(s2)CCC3)c2ccc(Cl)cn2)c1,,CCO,,BrBr,,test
+US05668161,CS(=O)(=O)c1ccc(C(Br)C(=O)c2ccc(F)cc2)cc1.NC(=S)c1cccnc1>>CS(=O)(=O)c1ccc(-c2sc(-c3cccnc3)nc2-c2ccc(F)cc2)cc1,,CC#N,,,,test
+US20090105302A1,C=CCCCCN(C)C(=O)C1CC(O)CC1C(=O)NC1(C(=O)OCC)CC1C=C>>C=CCCCCN(C)C(=O)C1CC(O)CC1C(=O)NC1(C(=O)O)CC1C=C,,CN(C)C=O,,Cl,[Li+].[OH-],test
+US20100137305A1,NC(N)=S.O=C(Nc1ccc(I)cc1F)C1CC1>>O=C(Nc1ccc(S)cc1F)C1CC1,[Ni],CN1CCCC1=O,,,,test
+US06194454B1,COc1ccc(O)cc1C(C)C.Cc1cc([N+](=O)[O-])cc(C#N)c1Cl>>COc1ccc(Oc2c(C)cc([N+](=O)[O-])cc2C#N)cc1C(C)C,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
+US05426226,CC(C)=NO.CCCN(CCC)C1CCc2cccc(C(=O)c3ccccc3F)c2C1>>CCCN(CCC)C1CCc2cccc(C(=O)c3ccccc3ON=C(C)C)c2C1,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
+US20150329538A1,Nc1c(Br)cccc1C(=O)NC1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c2c(Br)cccc2c(=O)n1C1CCOCC1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
+US20050101614A1,CN.COC(=O)c1c2cccc(-c3ccc(Cl)cc3Cl)c2nn1C>>CNC(=O)c1c2cccc(-c3ccc(Cl)cc3Cl)c2nn1C,,CO,,,,test
+US20100249229A1,CCC1=C[C@@H]2[C@H](C1)C[C@@]2(CC(=O)OC(C)(C)C)C[N+](=O)[O-]>>CCC1=C[C@@H]2[C@H](C1)C[C@]2(CN)CC(=O)OC(C)(C)C,[Fe],CCO,O,[Cl-].[NH4+],,test
+US20110263588A1,Cn1nc(C(=O)Nc2cccc(Cl)c2)c2cnc3ccccc3c21>>Cn1nc(C(=O)Nc2cccc(Cl)c2)c2c1-c1ccccc1NC2,,C1CCOC1,CCO,[BH4-].[Na+],,test
+US05547962,Cc1c(F)c(F)cc(C(=O)O)c1F.O=[N+]([O-])O>>Cc1c(F)c(F)c([N+](=O)[O-])c(C(=O)O)c1F,,O=S(=O)(O)O,,,,test
+US06063892,CC(C)(c1ccc([N+](=O)[O-])cc1)c1ccc([N+](=O)[O-])cc1>>CC(C)(c1ccc(N)cc1)c1ccc(N)cc1,[Pd],C1COCCO1,,,,test
+US20160108040A1,CS(=O)(=O)Cl.C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cncc(OCCO)c4)c4ccccc43)cn12>>C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cncc(OCCOS(C)(=O)=O)c4)c4ccccc43)cn12,,ClCCl,,CCN(C(C)C)C(C)C,,test
+US20090275624A1,COc1ccc(CN)cc1.Cc1nc2c(s1)C(=O)C=C(NCCCBr)C2=O>>COc1ccc(CNCCCNC2=CC(=O)c3sc(C)nc3C2=O)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
+US20080214641A1,CC(C)C(=O)Cl.NC(=O)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1>>CC(C)C(=O)NC(=O)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
+US20090221555A1,COc1c([N+](=O)[O-])cc(Cl)c2c1C(=O)C[C@@H](NC(C)=O)CC2>>COc1c([N+](=O)[O-])cc(Cl)c2c1C(O)C[C@@H](NC(C)=O)CC2,,CO,,O,[BH4-].[Na+],test
+US08242134B2,CC=O.CC[C@H](NC(=O)c1c(C)n(N)c(=O)c2ccccc12)c1ccccc1>>CCNn1c(C)c(C(=O)N[C@@H](CC)c2ccccc2)c2ccccc2c1=O,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
+US05308830,CCN(CC)C(=O)Cl.O=S(=O)(CC1CCC1)c1nc[nH]n1>>CCN(CC)C(=O)n1cnc(S(=O)(=O)CC2CCC2)n1,,c1ccncc1,,Cl,,test
+US05292742,CC=CCCCn1nnc(-c2ccc3[nH]c(CCCC)nc(=O)c3c2)n1.N#Cc1ccccc1-c1ccc(CBr)cc1>>C=CCCCCn1nnnc1-c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C#N)cc3)c(=O)c2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
+US06492416B1,CSc1ccc(C2=C(c3ccccc3)C(=O)C(C)(C)O2)cc1Cl.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc(C2=C(c3ccccc3)C(=O)C(C)(C)O2)cc1Cl,,ClCCl,,O=C([O-])O.[Na+],,test
+US20160200724A1,CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN(C(=O)OC(C)(C)C)[C@H]3C(C)C)cc1>>CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN[C@H]3C(C)C)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20110263598A1,C#Cc1ccc(C=O)cc1.C1CCNC1>>C#Cc1ccc(N2CCCC2)cc1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US20050032838A1,CCSc1cccc(O)c1.COCC(=O)N[C@H]1CC[C@@H](NC(=O)c2cc(F)cnc2Cl)CC1>>CCSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@H](NC(=O)COC)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
+US06511974B1,Cc1cn(-c2ccc(C(=O)O)cc2)cn1.O=C(Cl)C(=O)Cl>>Cc1cn(-c2ccc(C(=O)Cl)cc2)cn1,CN(C)C=O,ClCCl,,,,test
+US20050032786A1,CC(C)(C)OC(=O)CCc1cccc(C#N)n1.COc1ccc(C(=O)O)c(S)c1>>COc1ccc2c(=O)nc(-c3cccc(CCC(=O)OC(C)(C)C)n3)sc2c1,,c1ccncc1,,,,test
+US20080221134A1,C#CCn1c(=O)c2c(nc(C#Cc3cccc(OC)c3)n2C)n(C)c1=O>>C#CCn1c(=O)c2c(nc(C#Cc3cccc(O)c3)n2C)n(C)c1=O,,ClCCl,,BrB(Br)Br,,test
+US04503073,CCCSC(C(N)=O)c1cc(C)cc(C(=O)c2ccc(F)cc2)c1N>>Cc1cc(CC(N)=O)c(N)c(C(=O)c2ccc(F)cc2)c1,[Ni],C1CCOC1,,,,test
+US20130143914A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1.N[C@H]1CC[C@H](Oc2ccc3nnc(-c4ccccc4SCCOC4CCCCO4)n3c2)c2ccccc21>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@H](Oc3ccc4nnc(-c5ccccc5SCCOC5CCCCO5)n4c3)c3ccccc32)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
+US20100298336A1,Cc1c(Cl)ccnc1Cl.O=C1CCC(=O)N1Br>>Clc1ccnc(Cl)c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
+US20150025087A1,CC(c1c(F)cccc1F)n1cc(C(=O)O)c2ncccc21.NCCF>>CC(c1c(F)cccc1F)n1cc(C(=O)NCCF)c2ncccc21,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
+US20100075948A1,CC(C)(C)[Si](C)(C)OCCOc1ccc(Cl)cc1C=O.N#CCc1ccc(Cl)cc1F>>CC(C)(C)[Si](C)(C)OCCOc1ccc(Cl)cc1/C=C(\C#N)c1ccc(Cl)cc1F,,CO,,C[O-].[Na+],,test
+US20030166639A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(F)cc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
+US20060276508A1,COc1cc(OCC2COC(C)(C)O2)cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c1.O=C(O)C(F)(F)F>>COc1cc(OCC(O)CO)cc(C(=O)NC2CCNCC2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
+US04717783,C[Si](C)(C)C1=CC=CC1.C[Si](C)(C)Cl>>C[Si](C)(C)C1=CCC([Si](C)(C)C)=C1,,,,[Li]CCCC,,test
+US20070161686A1,COc1cc(N)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1.CS(=O)(=O)Cl>>COc1cc(NS(C)(=O)=O)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
+US20110166164A1,CC(C)(C)OC(=O)NCCc1ccc(Oc2cc(C#N)ccn2)cc1>>N#Cc1ccnc(Oc2ccc(CCN)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US07074801B1,CCOC(=O)c1ccc(-c2ncnc3ccc(-c4cnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)c4)cc23)cc1F>>O=C(O)c1ccc(-c2ncnc3ccc(-c4cnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)c4)cc23)cc1F,,CCO,O,[Li+].[OH-],,test
+US04080505,CC(=O)OC(C)=O.CC(C)(COc1ccc(CC(Cl)C(N)=O)cc1)c1ccccc1>>CC(=O)NC(=O)C(Cl)Cc1ccc(OCC(C)(C)c2ccccc2)cc1,O=S(=O)(O)O,Cc1ccccc1,,,,test
+US20150307454A1,N#Cc1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C(F)(F)F)cc1.NO>>NC(=NO)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C(F)(F)F)cc1,,CCO,,CCN(CC)CC,Cl,test
+US20090130076A1,CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)c(F)c(CBr)cc2s1.CCCC[Sn](CCCC)(CCCC)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)c(F)c(Cc3ccc([N+](=O)[O-])cc3)cc2s1,,C1COCCO1,,,,test
+US20110130445A1,COC(=O)CC1(c2ccc(Cl)c(NC(=O)C(c3ccc(Cl)cc3)[C@@H](C)C(F)(F)F)c2)CCC1>>C[C@H](C(C(=O)Nc1cc(C2(CC(=O)O)CCC2)ccc1Cl)c1ccc(Cl)cc1)C(F)(F)F,,C1COCCO1,,Cl,[Na+].[OH-],test
+US04855086,OCCCC#Cc1ccccc1>>O=CCCC#Cc1ccccc1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
+US20070244118A1,CC(Br)CCCC(=O)Cl.NC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(N2CCCCCC2=O)CC1,,C1CCOC1,,CCN(CC)CC,,test
+US20110053933A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(Oc2ccc(F)cc2)CC1.Cl>>C[C@H](N)C(=O)N1CCC(Oc2ccc(F)cc2)CC1.Cl,,CCO,,,,test
+US20090291988A1,Brc1ccc(Br)nc1.O=C(OCC(F)(F)F)C(F)(F)F>>O=C(c1ccc(Br)cn1)C(F)(F)F,,Cc1ccccc1,,[Li]CCCC,,test
+US20050250798A1,O=C1Nc2ccc([N+](=O)[O-])cc2C1=O.OCCCO>>O=C1Nc2ccc([N+](=O)[O-])cc2C12OCCCO2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
+US20150057271A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=C(O)C(F)(F)F.O=S(=O)(Nc1cncs1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1Br>>O=C(O)C(F)(F)F.O=S(=O)(Nc1cncs1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1C1=CCNCC1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
+US20130143863A1,COC(=O)c1ccc(C#N)cc1CBr.COc1ccc(CN)cc1>>COc1ccc(CN2Cc3cc(C#N)ccc3C2=O)cc1,,C1CCOC1,CCOC(C)=O,,,test
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+US20140378446A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1n(-c1ccc(Oc3ccccc3)cc1)c(=O)n2[C@@H]1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
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+US06579902B1,CO[C@@H]1[C@@H](O)[C@@H](O)C(O)OC1(C)C.Cc1c(O)ccc2c(OC(c3ccccc3)c3ccccc3)cc(=O)oc12>>CO[C@@H]1[C@@H](O)[C@@H](O)[C@H](Oc2ccc3c(OC(c4ccccc4)c4ccccc4)cc(=O)oc3c2C)OC1(C)C,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
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+US06248740B1,CCOC(=O)C(C)(C)c1cn2nc(NCCCN3CCC(NC(c4ccccc4)c4ccccc4)CC3)ccc2n1>>CC(C)(C(=O)O)c1cn2nc(NCCCN3CCC(NC(c4ccccc4)c4ccccc4)CC3)ccc2n1,,CCO,,[Na+].[OH-],,test
+US20150051199A1,CC(C)(C)[S@@](=O)/N=C/c1ccc(Cl)cc1F.CC[Mg]Br>>CC[C@@H](N[S@](=O)C(C)(C)C)c1ccc(Cl)cc1F,,C1CCOC1,O,CCOCC,[Cl-].[NH4+],test
+US20110269956A1,C[C@H]1C[C@@H](c2nc(-c3ccc(-c4ccc5cc(-c6c[nH]c([C@@H]7C[C@H](C)CN7C(=O)OC(C)(C)C)n6)ccc5c4)cc3)c[nH]2)N(C(=O)OC(C)(C)C)C1>>C[C@@H]1CN[C@H](c2nc(-c3ccc(-c4ccc5cc(-c6c[nH]c([C@@H]7C[C@H](C)CN7)n6)ccc5c4)cc3)c[nH]2)C1,,C1COCCO1,CO,Cl,,test
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+US20120196884A1,Cc1ccc(N=C=O)cc1[N+](=O)[O-].Nc1ccccc1>>Cc1ccc(NC(=O)Nc2ccccc2)cc1[N+](=O)[O-],,CCOC(C)=O,,,,test
+US20080274907A1,CCN(CCCC(=O)[O-])c1cc(O)c(-c2c3ccc(=[N+](C)C)cc-3oc3cc(N(C)C)ccc23)cc1OC.ClC(Cl)Cl.O=C1CCC(=O)N1O>>CCN(CCCC(=O)ON1C(=O)CCC1=O)c1cc(O)c(-c2c3ccc(=[N+](C)C)cc-3oc3cc(N(C)C)ccc23)cc1OC.[Cl-],,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
+US04683303,C=C(C)C(C(=O)OC)N1C(=O)[C@@H](NC(=O)OCc2ccccc2)[C@@H]1OC(C)=O>>COC(=O)C(=C(C)C)N1C(=O)[C@@H](NC(=O)OCc2ccccc2)[C@@H]1OC(C)=O,,ClCCl,,CCN(CC)CC,,test
+US05550134,CN1C(=O)CC[C@]2(C)c3ccc(S)cc3CC[C@@H]12.O=[N+]([O-])c1ccc2nc(Cl)ccc2c1>>CN1C(=O)CC[C@]2(C)c3ccc(Sc4ccc5cc([N+](=O)[O-])ccc5n4)cc3CC[C@@H]12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
+US05258382,CCOC(=O)C(C(=O)OCC)n1cccc1.O=C(Cl)C(Cl)(Cl)Cl>>CCOC(=O)C(C(=O)OCC)n1cccc1C(=O)C(Cl)(Cl)Cl,,ClC(Cl)Cl,,,,test
+US20040106655A1,BrBr.CC(C)Oc1ccc(N)cc1>>CC(C)Oc1ccc(N)c(Br)c1,,CC(=O)O,,,,test
+US20120309760A1,CC(C)(C)OC(=O)c1ccc(F)cc1.NC1CCNCC1>>CC(C)(C)OC(=O)c1ccc(N2CCC(N)CC2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
+US20090099187A1,COc1ccc(Cl)cc1N.COc1ccc(S(=O)(=O)Cl)c2c1C[C@@H](NC(=O)C(F)(F)F)CO2>>COc1ccc(Cl)cc1NS(=O)(=O)c1ccc(OC)c2c1OC[C@H](NC(=O)C(F)(F)F)C2,,ClC(Cl)Cl,,c1ccncc1,,test
+US05210092,CCCCc1nc2cccnc2n1Cc1ccc(-c2cc(Cl)sc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nc2cccnc2n1Cc1ccc(-c2cc(Cl)sc2-c2nnn[nH]2)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
+US05151420,Nc1ccc(C2=NNC(=O)CC2)cc1.O=C(CCc1ccccc1)c1ccc(O)cc1O>>O=C1CCC(c2ccc(N=C(CCc3ccccc3)c3ccc(O)cc3O)cc2)=NN1,,CCOC(C)=O,,,,test
+US20090197864A1,C[C@@H](Oc1c(N)ncc2c(C3=CCNCC3)coc12)c1c(Cl)ccc(F)c1Cl.O=C(O)CO>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(=O)CO)CC3)coc12)c1c(Cl)ccc(F)c1Cl,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
+US20070021443A1,C[C@H](c1cccnc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(N)nc21.N#Cc1ccc([N+](=O)[O-])c(F)c1>>C[C@H](c1cccnc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(Nc3cc(C#N)ccc3[N+](=O)[O-])nc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
+US04613208,Nc1ccc(-c2ccc(O)cc2)cc1.O=Nc1ccc([N+](=O)[O-])cc1Cl>>O=[N+]([O-])c1ccc(N=Nc2ccc(-c3ccc(O)cc3)cc2)c(Cl)c1,,CC(=O)O,,,,test
+US20040110945A1,CCOC(=O)Cc1cc(Cl)c(N)cc1F.Cn1cc(C(=O)O)c2cc(F)ccc21>>CCOC(=O)Cc1cc(Cl)c(NC(=O)c2cn(C)c3ccc(F)cc23)cc1F,,Cl,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
+US20110190490A1,CSc1nc(O)c(NC(=O)c2cccc(C)c2)c(O)n1>>CSc1nc(O)c2nc(-c3cccc(C)c3)oc2n1,,O=P(Cl)(Cl)Cl,,CCOCC,,test
+US20140315220A1,COc1ccc(C(SCCC(=O)ON2C(=O)CCC2=O)(c2ccc(OC)cc2)c2ccc(OC)c(C#CCCC(=O)NCc3ccccc3)c2)cc1.NCCCOCCOCCOCCCNC(=O)C1(F)C#CCCCCC1>>COc1ccc(C(SCCC(=O)NCCCOCCOCCOCCCNC(=O)C2(F)C#CCCCCC2)(c2ccc(OC)cc2)c2ccc(OC)c(C#CCCC(=O)NCc3ccccc3)c2)cc1,,ClCCl,,CCN(CC)CC,,test
+US20070298104A1,CCOC(=O)CN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O.Cc1nc2ccc(O)cc2s1>>CCOC(=O)CN1C(=O)c2ccc(Oc3ccc4nc(C)sc4c3)cc2C1=O,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
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+US20050192300A1,CC(C)(C)OC(=O)N1CCNCC1.Cc1nc(NC(=O)CCl)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1>>Cc1nc(NC(=O)CN2CCN(C(=O)OC(C)(C)C)CC2)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1,,CN(C)C=O,,,,test
+US05075502,CC(=O)Nc1c(I)c(C(=O)NCC(O)CC(O)CO)c(I)c(C(=O)NCC(O)CC(O)CO)c1I.OCCCl>>CC(=O)N(CCO)c1c(I)c(C(=O)NCC(O)CC(O)CO)c(I)c(C(=O)NCC(O)CC(O)CO)c1I,,[Na+],[OH-],O=S(=O)(O)O,,test
+US20120258953A1,CC(C)(C)OC(=O)N1CCC(O)(C(F)(F)F)CC1>>OC1(C(F)(F)F)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20060094749A1,Cc1ncc(CNC(=O)c2ccc(-c3ccc(NO)nc3)cc2)c2c1OC(C)(C)OC2>>Cc1ncc(CNC(=O)c2ccc(-c3ccc(N)nc3)cc2)c2c1OC(C)(C)OC2,[Pd],CCOC(C)=O,,,,test
+US20090247517A1,CN1CCNCC1.O=C(O)c1ccc(-n2ncc3c(=O)n(-c4ccc(Cl)cc4)c(-c4ccc(Cl)cc4Cl)nc32)cc1>>CN1CCN(C(=O)c2ccc(-n3ncc4c(=O)n(-c5ccc(Cl)cc5)c(-c5ccc(Cl)cc5Cl)nc43)cc2)CC1,,O=S(Cl)Cl,,,,test
+US20140343092A1,COC(=O)CN(C)C(=O)c1c(C(=O)OC)c2c(n1Cc1ccc(F)cc1)CCOC2>>COC(=O)c1c(O)c2c3c(n(Cc4ccc(F)cc4)c2c(=O)n1C)CCOC3,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
+US20100261710A1,O=C(O)c1cn2c3c(cccc13)CCC2.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>O=C=Nc1cn2c3c(cccc13)CCC2,,Cc1ccccc1,,CCN(CC)CC,,test
+US20080161328A1,CCOC(=O)Cl.Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O>>CCOC(=O)Nc1cccc2nc(C)n(C3CCC(=O)NC3=O)c(=O)c12,,C1CCOC1,,,,test
+US20040142926A1,Br.COc1ccc2nc(C)ccc2c1Br>>Br.Cc1ccc2c(Br)c(O)ccc2n1,,Br,,,,test
+US20140148459A1,COC(=O)C(CCn1nnc2ccc(C)cc2c1=O)Sc1ccc(N)cc1.COc1ccc(C(=O)Cl)cc1>>COC(=O)C(CCn1nnc2ccc(C)cc2c1=O)Sc1ccc(NC(=O)c2ccc(C)cc2)cc1,,ClCCl,,O,c1ccncc1,test
+US20150065705A1,CN(C)C=O.FC(F)(F)c1cc2cc(Br)ccc2o1>>O=Cc1ccc2oc(C(F)(F)F)cc2c1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,[Cl-].[NH4+],test
+US20110263658A1,COCCc1ccccc1-c1ccc(C(CNC(=O)OC(C)(C)C)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1>>COCCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1,,ClCCl,,C1COCCO1,Cl,test
+US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCN)cs1.CCCCCCCI.COC(=O)c1cnc(Cl)c(Cl)c1>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(C(=O)OC)cc1Cl,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
+US20150105394A1,ClCCc1c(Cl)ncnc1-c1ccccc1.NN>>c1ccc(-c2ncnc3c2CCNN3)cc1,,C1CCOC1,,,,test
+US20050049262A1,BrCc1ccccc1.CC(=O)O[C@@H](C)CCCCn1c(=O)c2[nH]c(CO)nc2n(C)c1=O>>CC(=O)O[C@@H](C)CCCCn1c(=O)c2c(nc(CO)n2Cc2ccccc2)n(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20130267546A1,COC(=O)c1c(OC)cc(N(C)C)nc1C>>COc1cc(C)nc(N(C)C)c1,,Cl,,O,,test
+US20050032786A1,C1COCCN1.N#Cc1ccnc(Cl)c1>>N#Cc1ccnc(N2CCOCC2)c1,,CN1CCCC1=O,,O,,test
+US04788304,OCCCCCOc1ccc(Cl)cc1>>O=CCCCCOc1ccc(Cl)cc1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
+US20130203802A1,BrP(Br)Br.Cc1ccnc(CO)c1F>>Cc1ccnc(CBr)c1F,,C1CCOC1,,,,test
+US07053099B1,N#Cc1c(N)cccc1F.Oc1ccccc1>>N#Cc1c(N)cccc1Oc1ccccc1,,CS(C)=O,,[H-].[Na+],,test
+US20160207949A1,CC(=S)OCCP(=O)(CCO)CCO.CSS(C)(=O)=O>>CS(=S)CCP(=O)(CCO)CCO,,CO,O,Cl,[Na+].[OH-],test
+US04820838,CCOc1ccc(CC2=[NH+]CCc3cc(OCC)c(OCC)cc32)cc1OCC.Cn1c(=O)c2c(ncn2CC(=O)[O-])n(C)c1=O>>CCOc1ccc(CC2=[NH+]CCc3cc(OCC)c(OCC)cc32)cc1OCC.Cn1c(=O)c2c(ncn2CC(=O)[O-])n(C)c1=O,,CC(C)=O,,O,,test
+US20140200231A1,O=C(O)COCCc1cnnn1Cc1ccccc1>>O=C(O)COCCc1cnn[nH]1,Cl[Pd]Cl,CC(C)O,O,[H][H],,test
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+US20050154045A1,CCN=C=O.O=C(Nc1ccc(-c2ccc(CO)cc2)cc1)[C@H]1CN2CCC1CC2>>CCNC(=O)OCc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1,,C1CCOC1,CN(C)C=O,,,test
+US20060293540A1,CC(=O)ONC(=N)c1ccc(-c2ccc(-c3ccc(C(=N)NOC(C)=O)o3)o2)cc1>>CC(=O)O.N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)o3)o2)cc1,[Pd],CC(=O)O,,CCO,,test
+US05563174,CCOC(=O)CCN(SN(CCC(=O)OCC)C(C)(C)Cl)C(C)(C)Cl.CCOC(=O)NN=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1>>CCOC(=O)CCN(SN(N=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1)C(=O)OCC)C(C)C,,C1CCOC1,,[H][H],[H-].[Na+],test
+US20020177578A1,O=C1CCN(C(=O)CCc2ccccc2)CC1.[NH4+]>>NC1CCN(C(=O)CCc2ccccc2)CC1,,CO,,[BH3-]C#N.[Na+],,test
+US20120129872A1,COc1ccc(S(N)(=O)=O)cc1N.S=C(Cl)Cl>>COc1ccc(S(N)(=O)=O)cc1N=C=S,,ClC(Cl)Cl,O,CCOC(C)=O,O=C([O-])O.[Na+],test
+US20030092677A1,Cc1nccn1-c1cccc(C(=O)CC(=O)Nc2cc(-c3ccc(F)cc3F)ccc2NC(=O)OC(C)(C)C)c1>>Cc1nccn1-c1cccc(C2=Nc3ccc(-c4ccc(F)cc4F)cc3NC(=O)C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
+US20160184318A1,C1COCCN1.Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(CC(=O)O)CC2)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(CC(=O)N3CCOCC3)CC2)n1,,CN1CCCC1=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
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+US20150175594A1,CCN(CC)S(F)(F)F.OC1CCC(OCc2ccccc2)CC1>>FC1CCC(OCc2ccccc2)CC1,,ClCCl,,,,test
+US20110065708A1,CC(=O)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1.NO>>C/C(=N\O)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1,,CO,,Cl,[Na+].[OH-],test
+US06329381B1,N#CCCCCl.Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1>>N#CCCCSc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US20030187023A1,Cc1cc(N2CCC(N(CCNC(=O)OC(C)(C)C)C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)ccn1>>CC(=O)NCCN(C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccnc(C)c2)CC1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
+US20150111885A1,COc1cc(F)c(CSC)cc1Br.O=S([O-])OO>>COc1cc(F)c(CS(C)(=O)=O)cc1Br,,CO,,O,,test
+US20140336106A1,COC(=O)C(CC#N)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC>>COC(=O)C(CCN)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC,[Pd],CC(=O)O,,,,test
+US20060142265A1,CCOC(=O)CNCc1ccc(OC)cc1.Nc1ncc(Br)cc1CBr>>CCOC(=O)CN(Cc1ccc(OC)cc1)Cc1cc(Br)cnc1N,,CN(C)C=O,O,Br,CCN(CC)CC,test
+US20150005277A1,NC(=O)c1c(N)c2cc([N+](=O)[O-])ccc2n1-c1ccc(Oc2ccccc2)cc1>>NC(=O)c1c(N)c2cc(N)ccc2n1-c1ccc(Oc2ccccc2)cc1,[Pd],CO,,,,test
+US20130109696A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1.COc1ccc(S)cc1>>COc1ccc(Sc2cc(F)c(S(=O)(=O)N(Cc3ccc(OC)cc3OC)c3nncs3)cc2Cl)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
+US20100144758A1,CCCc1cn(-c2cccc(C)c2)c2ncnc(Cl)c12.NC1CCOCC1>>CCCc1cn(-c2cccc(C)c2)c2ncnc(NC3CCOCC3)c12,,CCO,,CC(=O)[O-].[Na+],,test
+US20120101134A1,CCOC(=O)CCCc1cccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c1C(F)(F)F>>CC(C)Oc1ccc(-c2nc(-c3cccc(CCCC(=O)O)c3C(F)(F)F)no2)cc1C#N,,CC(C)O,O,Cl,[Na+].[OH-],test
+US20160145204A1,CCCCC=CCCc1ccccc1C>>CCCCCCCCc1ccccc1C,[Pd],CCOC(C)=O,,,,test
+US20070099938A1,Cl.Nc1nccc(-c2cc(OCC(F)(F)F)ccc2OCC(F)(F)F)n1>>FC(F)(F)COc1ccc(OCC(F)(F)F)c(-c2ccnc(Cl)n2)c1,,CC(=O)O,,O=N[O-].[Na+],,test
+US20050192302A1,N[C@H]1CCN(C(=O)C2CCN(c3cccc(C(F)(F)F)n3)CC2)C1.O=C1CCC(O)(c2ccc(-c3ncccn3)cn2)CC1>>O=C(C1CCN(c2cccc(C(F)(F)F)n2)CC1)N1CC[C@H](NC2CCC(O)(c3ccc(-c4ncccn4)cn3)CC2)C1,,ClCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US20120065231A1,CCCN(CC1OCCO1)c1cc(Br)c(C#N)s1>>CCCN(CC=O)c1cc(Br)c(C#N)s1,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
+US20090111859A1,C=C(C)C(CC(=O)OCC)c1ccc(OC2CCCCO2)cc1>>C=C(C)C(CC(=O)OCC)c1ccc(O)cc1,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
+US20040259904A1,COc1cc2c(cc1O)-c1c(c(-c3ccc(-c4ccc(OCOCC[Si](C)(C)C)cc4)cc3)nn1COCC[Si](C)(C)C)C2.O=S(=O)(Nc1ccccc1)C(F)(F)F>>COc1cc2c(cc1OS(=O)(=O)C(F)(F)F)-c1c(c(-c3ccc(-c4ccc(OCOCC[Si](C)(C)C)cc4)cc3)nn1COCC[Si](C)(C)C)C2,,C1CCOC1,,[H-].[Na+],,test
+US05374615,CCCCc1nc(Cl)c(C=O)[nH]1.N#Cc1ccccc1-n1cnc2c(CBr)cccc21>>CCCCc1nc(Cl)c(C=O)n1Cc1cccc2c1ncn2-c1ccccc1C#N,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
+US20050277689A1,COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12.O=S(=O)(O)O>>COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12.O=S(=O)([O-])[O-],,O,,CC(C)=O,,test
+US20070265268A1,COCOc1cc(COCc2ccccc2)c(C=O)c(OCOC)c1.O>>COCOc1cc(COCc2ccccc2)c(C(=O)O)c(OCOC)c1,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
+US20140274933A1,CNc1ccc2nc(C)oc2c1.O=C(O)CBr>>Cc1nc2ccc(N(C)C(=O)CBr)cc2o1,CN(C)c1ccncc1,ClCCl,O,CCN=C=NCCCN(C)C,Cl,test
+US04579845,CCC(C)N.CSC(=N)N(C#N)CC1CCN(CC2COc3ccccc3O2)CC1>>CCC(C)NC(=N)N(C#N)CC1CCN(CC2COc3ccccc3O2)CC1,,c1ccncc1,,,,test
+US20150175601A1,C=CC(=O)Nc1cccc(-c2cccc3cnc(Cl)nc23)c1.CN1CCN(c2cc(F)c(N)c(F)c2)CC1>>C=CC(=O)Nc1cccc(-c2cccc3cnc(Nc4c(F)cc(N5CCN(C)CC5)cc4F)nc23)c1,,CCCCO,,O=C(O)C(F)(F)F,,test
+US20130345181A1,Cn1nccc1B1OC(C)(C)C(C)(C)O1.Nc1ccc(Br)cc1Cl>>Cn1nccc1-c1ccc(N)c(Cl)c1,,CO,COCCOC,,,test
+US20040171623A1,CCCn1c(Cl)cc(=O)n(C)c1=O.[SH-]>>CCCn1c(S)cc(=O)n(C)c1=O,,CCO,,O,,test
+US20090137580A1,Clc1ncnc2cc[nH]c12.O=C(OCCBr)c1ccccc1>>O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
+US20070010542A1,Cc1c(OCC2(C)OCC3(CO2)OCCO3)ccnc1CSc1nc2ccccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Cc1c(OCC2(C)OCC3(CO2)OCCO3)ccnc1CS(=O)c1nc2ccccc2[nH]1,,CO,,Cc1ccccc1,,test
+US20060111353A1,CCOC(=O)/C(Br)=C/C1CCCCC1.CSc1ccc(B(O)O)cc1>>CCOC(=O)/C(=C/C1CCCCC1)c1ccc(SC)cc1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
+US20150094296A1,CC[C@]1(C#N)CCN(c2ccnc(Nc3cnn(C(C)(C)C(=O)OC(C)(C)C)c3)n2)C1=O.Cl>>CC[C@]1(C#N)CCN(c2ccnc(Nc3cnn(C(C)(C)C(=O)O)c3)n2)C1=O.Cl,,CCOC(C)=O,,,,test
+US05438052,Cc1cc(Cl)n2nc(CN=[N+]=[N-])nc2n1.NC(N)=S>>Cc1cc(S)n2nc(CN=[N+]=[N-])nc2n1,,CCO,,,,test
+US20070208064A1,CC(=O)Cl.CCOC(=O)CNc1ccc(C)cc1>>CCOC(=O)CN(C(C)=O)c1ccc(C)cc1,,C1CCOC1,,,,test
+US20100240708A1,CCOC(=O)[C@@H]1CCC[C@@H]1NS(=O)(=O)c1ccc(Cl)cc1>>O=S(=O)(N[C@@H]1CCC[C@@H]1CO)c1ccc(Cl)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
+US20120238569A1,COC(=O)c1sc(C)cc1C#N.O=C1CCC(=O)N1Br>>COC(=O)c1sc(CBr)cc1C#N,,ClC(Cl)(Cl)Cl,,,,test
+US20040214822A1,Cl[Mg]Cc1ccccc1.N#CC1(N2CCCC2)CCC2(CC1)OCCO2>>c1ccc(CC2(N3CCCC3)CCC3(CC2)OCCO3)cc1,,C1CCOC1,C1CCOC1,[Cl-].[NH4+],,test
+US20150126485A1,NCCC(O)C(=O)O.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2ccn[nH]2)c1>>O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(NCCC(O)C(=O)O)c(-c2ccn[nH]2)c1,,CN1CCCC1=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
+US06924300B2,CCN=C=NCCCN(C)C.Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CC(=O)O)c2ccccc2)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CC(N)=O)c2ccccc2)cc1,,O,,CN(C)C=O,Cl,test
+US20110021493A1,CC(C)(C)OC(=O)Nc1cc(O)c(Cl)c(Cl)c1.Cl>>Cl.Nc1cc(O)c(Cl)c(Cl)c1,,CC(C)O,,C1COCCO1,,test
+US05859007,COc1ccc(N(C(=O)CN2C(=O)C(Cc3nn(C(=O)OC(C)(C)C)c4ccccc34)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1>>COc1ccc(N(C(=O)CN2C(=O)C(Cc3n[nH]c4ccccc34)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1,,C1COCCO1,,Cl,,test
+US20120232056A1,COC(=O)c1ccc2nc(-c3cncc(Br)c3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1cncc(Br)c1,,CO,,O,[Na+].[OH-],test
+US20080275116A1,O=C(O)Cc1ccccc1OCc1ccccc1.O=C1CCC(=O)N1Br>>O=C(O)Cc1cc(Br)ccc1OCc1ccccc1,,CCOC(C)=O,,ClCCl,,test
+US20140334027A1,CC(=O)c1ccc(-n2c3ccccc3c3cc(C(=O)c4c(C)cc(C)cc4C)c4ccccc4c32)cc1.CC(C)CC(=O)Cl>>CC(=O)c1ccc(-n2c3ccc(C(=O)CC(C)C)cc3c3cc(C(=O)c4c(C)cc(C)cc4C)c4ccccc4c32)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
+US04379167,OC(CCl)CCCl.Oc1ccccc1Cl>>OC(CCCl)COc1ccccc1Cl,,CC(C)O,,O,[K+].[OH-],test
+US20100278833A1,COC(=O)c1sc(-n2cnc3ncccc32)cc1OCc1ccccc1C(F)(F)F.N>>NC(=O)c1sc(-n2cnc3ncccc32)cc1OCc1ccccc1C(F)(F)F,,CO,,,,test
+US20130296436A1,Cc1cc([N+](=O)[O-])c(C)cc1OCC(F)(F)CC(C)(C)C>>CCCC(F)(F)COc1cc(C)c(N)cc1C,,CCO,,[H][H],,test
+US20040033988A1,CC(C)(C)[Si](C)(C)OC1CCC(CC(=O)O)CC1.NO>>CC(C)(C)[Si](C)(C)OC1CCC(CC(=O)NO)CC1,,CN(C)C=O,,On1nnc2ccccc21,,test
+US20100168418A1,Cc1cc(=O)n(CCN2CCC(N(Cc3ccc4c(c3)OCCO4)C(=O)OC(C)(C)C)CC2)c2cc(C3CCCCC3)ccc12.Cl>>Cc1cc(=O)n(CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c2cc(C3CCCCC3)ccc12.Cl,,CCOC(C)=O,,CO,,test
+US04681886,CCOC(=O)CCN(CC)C(=O)N1C[C@@H](Oc2cccc(C3NC(=O)c4cc(S(N)(=O)=O)c(Cl)cc4N3)c2)C[C@H]1C(=O)OCc1ccccc1>>CCOC(=O)CCN(CC)C(=O)N1C[C@@H](Oc2cccc(C3NC(=O)c4cc(S(N)(=O)=O)c(Cl)cc4N3)c2)C[C@H]1C(=O)O,[Pd],CCO,,,,test
+US20110144136A1,CCCCOc1nc(N)c2nc(OC)n(CC3CCNCC3)c2n1.IC1CCCCC1>>CCCCOc1nc(N)c2[nH]c(=O)n(CC3CCN(C4CCCCC4)CC3)c2n1,,CN(C)C=O,CS(C)=O,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
+US20080234237A1,CN1CCC(N2C(=O)CCc3cc([N+](=O)[O-])ccc32)CC1>>CN1CCC(N2C(=O)CCc3cc(N)ccc32)CC1,[Pd],CCO,,[H][H],,test
+US04408052,CCCCCCCCCCCCCCCCCCN=C=O.OCCO>>CCCCCCCCCCCCCCCCCCNC(=O)OCCO,,c1ccncc1,,,,test
+US20050209260A1,COc1cccc(O)c1C(C)=O.C[Mg]Br>>COc1cccc(O)c1C(C)(C)O,,C1CCOC1,CCOCC,O,[Cl-].[NH4+],test
+US05455258,BrCc1ccccc1.COc1ccc(S(=O)(=O)N[C@H](CC(C)C)C(=O)OC(C)(C)C)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)[C@H](CC(C)C)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,[H-].[Na+],,test
+US20090076070A1,CC(Oc1ccc(-c2nc(-c3cccc4c3ccn4CC(=O)NCc3ccccn3)no2)cc1C(F)(F)F)C(F)(F)F.Cl>>CC(Oc1ccc(-c2nc(-c3cccc4c3ccn4CC(=O)NCc3ccccn3)no2)cc1C(F)(F)F)C(F)(F)F.Cl,,ClCCl,,C1COCCO1,,test
+US04174959,CC(=O)c1ccccc1.Cc1nc2cc(C(F)(F)F)cc(N)c2n1C(C)C>>CC(=Nc1cc(C(F)(F)F)cc2nc(C)n(C(C)C)c12)c1ccccc1,,Cc1ccccc1C,,,,test
+US05576340,CC(C)(C)[Si](C)(C)Cl.CCOC(=O)[C@@H](O)c1ccccc1>>CCOC(=O)[C@@H](O[Si](C)(C)C(C)(C)C)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
+US20070027155A1,CI.Cc1cc(O)cnc1N1CCN(c2cc(-c3ccc(F)c(Cl)c3)nc(N3CCCC3C)n2)CC1>>COc1cnc(N2CCN(c3cc(-c4ccc(F)c(Cl)c4)nc(N4CCCC4C)n3)CC2)c(C)c1,,CN(C)C=O,,[H-].[Na+],,test
+US20140350002A1,CS(=O)(=O)Cl.Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CNCC4C3)nc21>>Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CN(S(C)(=O)=O)CC4C3)nc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
+US05120732,CC1(C)CN1.OCCS>>CC(C)(N)CSCCO,,COCCOC,,,,test
+US20050187243A1,CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)[O-])CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1>>CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)O)CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1,,O,,Cl,,test
+US20100272678A1,COC(=O)c1ccc(C)[se]1.O=[Se]=O>>COC(=O)c1ccc(C=O)[se]1,,CC(=O)O,,O,,test
+US20090012084A1,CC(C)=O.CC(Cl)Cl.COc1cc2nnc(C#N)c(Nc3ccc(C)cc3F)c2cc1C1=CCNCC1>>COc1cc2nnc(C#N)c(Nc3ccc(C)cc3F)c2cc1C1=CCN(C(C)C)CC1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US05210092,CI.COC(=O)c1ccc(-c2c[nH]cc2C#N)cc1>>COC(=O)c1ccc(-c2cn(C)cc2C#N)cc1,,CN(C)C=O,,[H-].[Na+],,test
+US20140057902A1,CCCC[Sn](CCCC)(CCCC)c1ccccc1.COc1cccc(C2=NCC(=O)N3CCc4c(I)cccc4C3=C2)c1>>COc1cccc(C2=NCC(=O)N3CCc4c(cccc4-c4ccccc4)C3=C2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
+US20050131239A1,CSc1ccc(B(O)O)cc1.O=C1OCC(Cl)=C1Cl>>CSc1ccc(C2=C(Cl)C(=O)OC2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,[Cs+].[F-],,test
+US20070238726A1,COc1ccc(Cn2ncc3c(N(CCN4CCOCC4)c4ccc([N+](=O)[O-])cc4F)ccnc32)cc1>>COc1ccc(Cn2ncc3c(N(CCN4CCOCC4)c4ccc(N)cc4F)ccnc32)cc1,,CCO,,,,test
+US20150368226A1,CC(C)(C)OC(=O)N1CCC2OC2C1.Fc1ccc2[nH]c3ccc(Cl)cc3c2c1>>CC(C)(C)OC(=O)N1CC[C@@H](n2c3ccc(F)cc3c3cc(Cl)ccc32)[C@H](O)C1,,CN(C)C=O,,,,test
+US20150038438A1,CC1CCc2cc(Cl)ccc2C(=O)C1.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C2CC(C)CCc3cc(Cl)ccc32)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
+US20130178460A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.Cc1ccc(NC(=O)c2csc3cnc(Cl)nc23)nc1C>>Cc1ccc(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)nc1C,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
+US20090176804A1,Cc1cccc2c1cc(-c1ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c1)n2C(=O)OC(C)(C)C>>Cc1cccc2[nH]c(-c3ccc(Cl)c(S(=O)(=O)NC4CCCCC4)c3)cc12,,ClCCl,,,,test
+US05216020,CI.O=C(O)C1Cc2ccsc2S1(=O)=O>>CC1(C(=O)O)Cc2ccsc2S1(=O)=O,,CN(C)C=O,,[H-].[Na+],,test
+US05539115,CCCCCCCCCCOc1cnc(-c2ccc(C=CCCO)cc2)nc1>>CCCCCCCCCCOc1cnc(-c2ccc(CCCCO)cc2)nc1,[Pd],C1CCOC1,,[H][H],,test
+US20070276000A1,COCOc1c(Br)c(C)cc2cc(OC)ccc12.OB(O)c1cccc(C(F)(F)F)c1>>COCOc1c(-c2cccc(C(F)(F)F)c2)c(C)cc2cc(OC)ccc12,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
+US20110263588A1,CCOC(=O)C(=O)OCC.CNN.O=C1CCCc2cccnc21>>CCOC(=O)c1nn(C)c2c1CCc1cccnc1-2,,CCO,,C,C[O-].[Na+],test
+US20080221180A1,CC(=O)NCCN.CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1>>CC(=O)NCCNS(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)s1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
+US20070244159A1,CC(=O)Cl.CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1CCN>>CC(=O)NCCn1c(C(C)(C)C)cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc21,,CN(C)C=O,,CCN(CC)CC,,test
+US20050228004A1,Nc1ncccc1OCc1ccccc1.O=C(CBr)c1ccc(F)cc1>>Fc1ccc(-c2cn3cccc(OCc4ccccc4)c3n2)cc1,,CCO,,,,test
+US07049312B1,O=C1COc2ccccc2N1.O=Cc1c[nH]c2ccccc12>>O=C1Nc2ccccc2OC1=Cc1c[nH]c2ccccc12,,CN(C)C=O,,C[O-].[Na+],,test
+US20140128386A1,COC(=O)[C@@H](N)CCC(F)(F)C(F)(F)F.O=C(Cl)OCc1ccccc1>>COC(=O)[C@H](CCC(F)(F)C(F)(F)F)NC(=O)OCc1ccccc1,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
+US05109000,CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(CC(=O)NCC(=O)OC(C)(C)C)SC(C)=O>>CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(CC(=O)NCC(=O)O)SC(C)=O,,O,O=C(O)C(F)(F)F,,,test
+US04167508,O=C(O)CCc1ccc(O)cc1.O=[N+]([O-])c1ccc(CBr)cc1>>O=C(CCc1ccc(O)cc1)OCc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,CCN(CC)CC,,test
+US20140065103A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)O)C1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H](CO)C1,,C1CCOC1,,,,test
+US04349552,CC(=O)CCN=C=O.O=c1[nH]cc(F)c(=O)[nH]1>>CC(=O)CCNC(=O)n1cc(F)c(=O)[nH]c1=O,,CC(=O)N(C)C,CCOC(C)=O,,,test
+US20060069088A1,COC(=O)c1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc1F>>COC(=O)c1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1F,[Pd],CCO,,[H][H],,test
+US04410534,CC(C)CCO.Cc1ccc(C(=O)c2ccc3n2CCCC3C(=O)O)cc1>>Cc1ccc(C(=O)c2ccc3n2CCCC3C(=O)OCCC(C)C)cc1,,CC(C)CCO,,Cl,,test
+US06057313,Nc1c([N+](=O)[O-])cc(Br)c2c1CN(Cc1ccccc1)CC2>>Nc1cc(Br)c2c(c1N)CN(Cc1ccccc1)CC2,[Ni],C1CCOC1,,,,test
+US20130196974A1,Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N3C[C@H](N)[C@H](O)C3)c2c1.N#CBr>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N3C[C@H]4N=C(N)O[C@H]4C3)c2c1,,CO,,CC(=O)[O-].[Na+],,test
+US20130217666A1,BrBr.O=C1CCCOc2cc(F)c(Br)cc21>>O=C1c2cc(Br)c(F)cc2OCCC1Br,,ClCCl,,,,test
+US20160083354A1,COC(=O)c1ccc(CBr)cc1.Nc1cccc(C(F)(F)F)n1>>COC(=O)c1ccc(CNc2cccc(C(F)(F)F)n2)cc1,,CC#N,,CCN(C(C)C)C(C)C,O,test
+US20020115700A1,O=C(Cl)c1ccc(Cl)c(Cl)c1.O=C1NC(=O)C(=Cc2c[nH]c3ccc(OCc4ccccc4)cc23)S1>>O=C1NC(=O)C(=Cc2cn(C(=O)c3ccc(Cl)c(Cl)c3)c3ccc(OCc4ccccc4)cc23)S1,,c1ccncc1,,CN(C)c1ccccn1,,test
+US20100105654A1,CS(=O)(=O)Cl.NC1CN(C(c2ccccc2)c2ccccc2)C1>>CS(=O)(=O)NC1CN(C(c2ccccc2)c2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
+US20020072603A1,O=C(Cl)C(c1ccc(Cl)cc1)c1c(Cl)cc(-n2ncc(=O)[nH]c2=O)cc1Cl>>O=c1cnn(-c2cc(Cl)c(C(CO)c3ccc(Cl)cc3)c(Cl)c2)c(=O)[nH]1,,C1COCCO1,,Cl,[BH4-].[Na+],test
+US20040132726A1,O=C(Cl)c1ccccc1.O=[N+]([O-])CCO>>O=C(OCC[N+](=O)[O-])c1ccccc1,,c1ccccc1,,,,test
+US06756378B2,CC#N.CCN(CC)CC.CCN=C=NCCCN(C)C.COC(=O)c1ccc(OC[C@@H]2C[C@H](N(C)C)CN2C(=O)OC(C)(C)C)cc1.Cl.ClCCl.O=C(O)C(F)(F)F.On1nnc2ccccc21>>COC(=O)c1ccc(OC[C@@H]2C[C@H](N(C)C)CN2C(=O)Cc2ccc(NC(=O)Nc3ccccc3Cl)c(OC)c2)cc1,,CC#N,ClCCl,C1CCOC1,,test
+US20070259881A1,CC(C)(O)CNc1c(N)cnc2ccccc12.O=C(Cl)CCl>>CC(C)(O)Cn1c(CCl)nc2cnc3ccccc3c21,,ClCCl,,CCN(CC)CC,,test
+US20090131458A1,BrCC[C@@H]1CCOC1.CCCCNc1nc(N)c2nc(OC)nc-2[nH]1>>CCCCNc1nc(N)c2nc(OC)n(CC[C@@H]3CCOC3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
+US04584285,CCOC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)N[C@@H](C)C(=O)OC(C)(C)C>>CCOC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)N[C@@H](C)C(=O)O,,O=C(O)C(F)(F)F,,,,test
+US20100173901A1,CC1(C)OB(c2cnn(CCF)c2)OC1(C)C.CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(-c3cnn(CCF)c3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,O,C1COCCO1,O=C([O-])O.[Na+],test
+US20120225854A1,C1COCCN1.CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2C=O)cc1)C(F)(F)F>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2CN2CCOCC2)cc1)C(F)(F)F,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
+US04410539,COC(=O)c1sc2cc(OC)ccc2c1C>>COC(=O)c1sc2cc(O)ccc2c1C,,ClCCl,,BrB(Br)Br,CO,test
+US20100261910A1,C#Cc1ccsc1.CC(=O)Nc1ccccc1OS(=O)(=O)c1ccc(C)cc1>>CC(=O)Nc1ccccc1C#Cc1ccsc1,,CCCCCCC,CCOC(C)=O,,,test
+US05292901,CC(=O)CSCCc1ccc2c(c1)OCO2.O=C(OO)c1cccc(Cl)c1>>CC(=O)CS(=O)CCc1ccc2c(c1)OCO2,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
+US05164510,CC(=O)OC(C)=O.O=[N+]([O-])c1ccc2c(c1)CCN2>>CC(=O)N1CCc2cc([N+](=O)[O-])ccc21,,c1ccncc1,,,,test
+US04767766,CI.COc1cccc(CSc2ncccc2C(=O)O)c1>>COC(=O)c1cccnc1SCc1cccc(OC)c1,,CC#N,,,,test
+US20100227858A1,C[C@H]1COCCN1c1cc(C(C)(C)S(C)(=O)=O)nc(Cl)n1.OB(O)c1cnc2[nH]ccc2c1>>C[C@H]1COCCN1c1cc(C(C)(C)S(C)(=O)=O)nc(-c2cnc3[nH]ccc3c2)n1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
+US20110311474A1,CCC1CC(OC2CCOCC2)CC1(CC)C(=O)O>>CCC1CC(OC2CCOCC2)CC1C(=O)O,,C1COCCO1,,[Na+].[OH-],,test
+US20030004181A1,COCc1nc(CO)cn1C.COCc1ncc(CO)n1C.O=C1CCC(=O)N1Cl>>COCc1nc(CO)c(Cl)n1C,,CCOCCO,,C1COCCO1,,test
+US04699928,CCOC(=O)C(C)(C(=O)OC(C)(C)C)C(F)F>>CCOC(=O)/C(C)=C/F,,O=C(O)C(F)(F)F,,,,test
+US20060106037A1,CC(O)C(CCCc1ccccc1)n1cnc(C(N)=O)c1N.CCOC(=O)Cc1ccc(OC(F)F)c(OC)c1>>COc1cc(Cc2nc3c(ncn3C(CCCc3ccccc3)C(C)O)c(=O)[nH]2)ccc1OC(F)F,,CCO,,[Na],,test
+US05246948,Cl.O=C(Cl)c1ccccc1.c1ccc(CNCCCSc2ccncc2)cc1>>Cl.O=C(c1ccccc1)N(CCCSc1ccncc1)Cc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
+US20160244414A1,CN(C)C=NC(=O)c1cn(-c2ccccc2)c(=O)cc1Oc1ccccc1.NN>>O=c1cc(Oc2ccccc2)c(-c2nc[nH]n2)cn1-c1ccccc1,,CC(=O)O,,O,,test
+US20090088322A1,COC(=O)c1cc(Cl)nc(Cl)n1.N>>COC(=O)c1cc(N)nc(Cl)n1,,CS(C)=O,,,,test
+US20110039843A1,FC(F)(F)c1ccc2oc(-c3ccncc3Br)nc2c1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc(-c2nc3cc(C(F)(F)F)ccc3o2)c(Br)c1,,CCOC(C)=O,,ClC(Cl)Cl,,test
+US20120322791A1,Brc1ccc(Br)nc1.O=C1CCC1>>OC1(c2ccc(Br)cn2)CCC1,,Cc1ccccc1,,[Li]CCCC,,test
+US20120232056A1,COC(=O)c1ccc2nc(-c3occc3-c3ccccc3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1occc1-c1ccccc1,,CO,O,[Na+].[OH-],,test
+US20110207947A1,CCCCCCCC(O[Si](C)(C)C(C)(C)C)C(O)C(O)/C(=C/C(=O)OC)C(=O)OC.COC(C)(C)OC>>CCCCCCCC(O[Si](C)(C)C(C)(C)C)C1OC(C)(C)OC1/C(=C/C(=O)OC)C(=O)OC,Cc1ccc(S(=O)(=O)O)cc1,CC(C)=O,,CCOCC,,test
+US03993646,CC1(CBr)S[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OCC(Cl)(Cl)Cl>>CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1,,c1ccccc1,,c1ccncc1,,test
+US20100168080A1,C[C@H]1CO[C@H](Cc2ccc(F)cc2)CN1Cc1ccccc1>>C[C@H]1CO[C@H](Cc2ccc(F)cc2)CN1,[Pd],CCO,,,,test
+US20140336185A1,CC(C)(C)OC(=O)CN(Cc1ccc(-c2noc(N)n2)cc1)C(=O)c1ccc([N+](=O)[O-])cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2nc(-c3ccc(CN(CC(=O)OC(C)(C)C)C(=O)c4ccc([N+](=O)[O-])cc4)cc3)no2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
+US20050054851A1,CC(C)(C)Cn1c(CBr)cc2cnc(C#N)nc21.c1nnn[nH]1>>CC(C)(C)Cn1c(Cn2cnnn2)cc2cnc(C#N)nc21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
+US20120277209A1,Fc1nccnc1C1CCCOCC1.O=C(c1ccc(O)cc1)c1nc2ccccc2[nH]1>>O=C(c1ccc(Oc2nccnc2C2CCCOCC2)cc1)c1nc2ccccc2[nH]1,,CN1CCCC1=O,O,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20120263670A1,COC(=O)c1cc(O)cc(C(=O)OC)c1>>O=C(O)c1cc(O)cc(C(=O)O)c1,,C1CCOC1,,[Li+].[OH-],,val
+US04360680,COc1ccc(NN)cc1.N#CC=Cc1ccccc1>>COc1ccc(N2N=C(N)CC2c2ccccc2)cc1,,CCO,,Cl,[Na],val
+US20150344437A1,CC(=O)c1ccc(S(=O)(=O)Cl)cc1.CNOC>>CON(C)S(=O)(=O)c1ccc(C(C)=O)cc1,,ClCCl,,c1ccncc1,,val
+US06350749B1,Cc1cn(C)c2c1C(=O)CC(c1ccccc1)C2.Cl.N=C(N)NN>>Cc1cn(C)c2c1C(=NNC(=N)N)CC(c1ccccc1)C2.Cl,,CCO,,Cl,O,val
+US05661161,CC/C=C/C=O.CCOC(=O)C(NC(C)=O)C(=O)OCC>>CCOC(=O)C1(C(=O)OCC)C(CC)CC(O)N1C(C)=O,,CCO,,[Na],,val
+US20080269193A1,N#Cc1c(F)c(F)c(F)c(F)c1F.NN>>N#Cc1c(F)c(F)c(NN)c(F)c1F,,C1COCCO1,,CCN(C(C)C)C(C)C,,val
+US20120252777A1,CC1(C)OB(c2ccc(C(=O)NCCc3cc[nH]c(=O)c3)cc2)OC1(C)C.COc1ccc(Nc2nc(Cl)nc3scnc23)cc1OC>>COc1ccc(Nc2nc(-c3ccc(C(=O)NCCc4cc[nH]c(=O)c4)cc3)nc3scnc23)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,val
+US05436359,CI.COc1c(O)c(CCCCCCCCCCO)c(C)c(OC(=O)c2cccnc2)c1OC>>COc1c(O)c(CCCCCCCCCCO)c(C)c(OC(=O)C2=CN(C)C=CC2)c1OC,,CN(C)C=O,,,,val
+US20060217380A1,COC(=O)c1cc(Cl)cn(C)c1=O>>Cn1cc(Cl)cc(C(=O)O)c1=O,,CO,,[Na+].[OH-],,val
+US20080039504A1,CC(C)N.N#CBr.NNC(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>CC(C)n1c(N)nnc1-c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,CC(=O)O,,,,val
+US20160031810A1,CCC1(CC)c2cc([N+](=O)[O-])ccc2-c2ccc([N+](=O)[O-])cc21>>CC1(C)c2cc(N)ccc2-c2ccc(N)cc21,,CN(C)C=O,,NN,O,val
+US20100029722A1,Cc1nc(C#N)sc1C(=O)NCc1ccccc1.NNC(=O)Cc1ccccc1>>Cc1nc(-c2n[nH]c(Cc3ccccc3)n2)sc1C(=O)NCc1ccccc1,,CCCCO,,O=C([O-])[O-].[K+].[K+],,val
+US20040053942A1,Fc1ccc(-c2nn3ccccc3c2Br)cc1.OB(O)c1ccnc(F)c1>>Fc1ccc(-c2nn3ccccc3c2-c2ccnc(F)c2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,val
+US20050124816A1,NC(=S)SCCC(F)=C(F)F.O=CCCl>>FC(F)=C(F)CCSc1nccs1,,C1COCCO1,,Cl,,val
+US20120142706A1,CC1(C(=O)O)CC1.Cc1cc(N(CC[C@@H]2C[C@@H]2C2CCN(c3ncc(Cl)cn3)CC2)C(=O)OC(C)(C)C)ncc1N>>CC(C)(C)OC(=O)N(CC[C@@H]1C[C@@H]1C1CCN(c2ncc(Cl)cn2)CC1)c1ccc(NC(=O)C2(C)CC2)nc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20140235628A1,O=C1OCc2cc(CCC3(O)CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)ccc21>>O=C1OCc2cc(CCC3=CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)ccc21,,c1ccccc1,,Cc1ccccc1S(=O)(=O)O,,val
+US20040138065A1,ClCCCBr.N#CC(C#N)Cc1ccc(C(F)(F)F)cc1>>N#CC(C#N)(CCCCl)Cc1ccc(C(F)(F)F)cc1,,CN(C)C=O,,[H-].[Na+],,val
+US20100016245A1,BrBr.CCCC(=O)O[C@@H]1[C@@H](OC(=O)CCC)[C@H](C)O[C@@H](Sc2ccccc2)[C@@H]1OCc1ccccc1>>CCCC(=O)O[C@@H]1[C@@H](OC(=O)CCC)[C@H](C)O[C@@H](Br)[C@@H]1OCc1ccccc1,,ClCCl,,,,val
+US20150050410A1,COc1ccc(C2CC(=O)c3c(O)cc(O)cc3O2)cc1O.O=S1(=O)CCCO1>>COc1ccc(C2CC(=O)c3c(O)cc(OCCCS(=O)(=O)O)cc3O2)cc1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US20120295903A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCNC(=O)OC(C)(C)C)c2cc1OC1CCCC1>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN)c2cc1OC1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US06258854B1,CC(=O)[O-].COc1ccc(C(=O)CBr)cc1>>COc1ccc(C(=O)COC(C)=O)cc1,,CO,,O,,val
+US20110136763A1,CCOC(=O)CC1OB(O)c2cc(O)cc(C)c21.O=[N+]([O-])c1cc(Cl)ccn1>>CCOC(=O)CC1OB(O)c2cc(Oc3ccnc([N+](=O)[O-])c3)cc(C)c21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20160120841A1,CCON=C1CC(c2ccc(C(=O)OC)cn2)Oc2cc(OC)ccc21>>COC(=O)c1ccc(C2CC(N)c3ccc(OC)cc3O2)nc1,[Ni],CO,,,,val
+US20130035326A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(NCCN3CCCCC3)nc2)cc1F>>Nc1ccc(-c2ccc(NCCN3CCCCC3)nc2)cc1F,,ClCCl,,O=C(O)C(F)(F)F,,val
+US06967201B1,CC(C)(C)OC(=O)N1CCN(c2cc(CO[Si](C)(C)C(C)(C)C)cc3ccoc23)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(CO)cc3ccoc23)CC1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,val
+US04061730,CCOC(C)=O.CN(C)c1ccc(C=C2C(=O)C3(C)CCC2C3(C)C)cc1.COS(=O)(=O)[O-]>>CC12CCC(C(=Cc3ccc([N+](C)(C)C)cc3)C1=O)C2(C)C.COS(=O)(=O)[O-],,CCOC(C)=O,,,,val
+US04510086,CC(=O)SC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)CC2S1>>O=C(OCc1ccc([N+](=O)[O-])cc1)C1C(=S)SC2CC(=O)N21,,C1COCCO1,O,c1c[nH]cn1,,val
+US20150065477A1,CCOC(=O)c1cccnc1-n1ccc(CCl)n1.FC1(F)CCNCC1>>CCOC(=O)c1cccnc1-n1ccc(CN2CCC(F)(F)CC2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20090286825A1,COC(=O)C(=O)c1c2n(c3ccccc13)CC(N(C)S(=O)(=O)c1ccc(F)cc1)CC2>>COC(=O)Cc1c2n(c3ccccc13)CC(N(C)S(=O)(=O)c1ccc(F)cc1)CC2,,C1CCOC1,CO,CC(=O)O,[BH4-].[Na+],val
+US04385925,CC1(C(=O)Cn2cncn2)COCOC1.ClCc1ccc(Cl)cc1>>CC1(C(=O)C(Cc2ccc(Cl)cc2)n2cncn2)COCOC1,,CN(C)C=O,,[H-].[Na+],,val
+US20110190342A1,Cc1ccc(Oc2ccc(C[C@H](N)C(=O)O)cc2)nc1.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>Cc1ccc(Oc2ccc(C[C@H](Nc3nc4ccc(Cl)cc4cc3C(=O)O)C(=O)O)cc2)nc1,,CS(C)=O,,,,val
+US20040048868A1,CCOc1cc(C(=O)OC)n(Cc2ccccc2)n1>>CCOc1cc(CO)n(Cc2ccccc2)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,val
+US20080280933A1,CCOC(OCC)c1nc2cc(F)c(F)cc2[nH]1.CI>>CCOC(OCC)c1nc2cc(F)c(F)cc2n1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20130236434A1,COC(=O)C[C@H](N)c1ccc2c(c1)OCO2.O=C=NCCOC(=O)N(Cc1cccs1)Cc1cccs1>>COC(=O)C[C@H](NC(=O)NCCOC(=O)N(Cc1cccs1)Cc1cccs1)c1ccc2c(c1)OCO2,,ClCCl,,,,val
+US20120202785A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc(F)cc1N[C@@H]1CC[C@@H](C#N)CC1>>C[C@H](N)c1nc2ccc(F)cc2n1[C@@H]1CC[C@@H](C#N)CC1,,CC(=O)O,,,,val
+US20100204240A1,Cc1ncccc1Oc1cc(Sc2ccccn2)cnc1Nc1nc([C@@H]2OC(C)(C)OC2(C)C)ns1.Cl>>Cc1ncccc1Oc1cc(Sc2ccccn2)cnc1Nc1nc([C@H](O)C(C)(C)O)ns1.Cl,,CCO,,,,val
+US20020045780A1,Cc1cc(C)c(S(=O)(=O)N(CCCC#N)CCCCC#N)c(C)c1>>Cc1cc(C)c(S(=O)(=O)N(CCCCN)CCCCCN)c(C)c1,[Ni],C1CCOC1,CO,[NH4+].[OH-],,val
+US20090270363A1,CCN(C)c1ccc(C#N)cc1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCN(C)c1ccc(C(N)=S)cc1,,CO,,,,val
+US06833421B1,COC(=O)c1cc(OCCCCCCCl)cc(C(=O)OC)c1>>OCc1cc(CO)cc(OCCCCCCCl)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,val
+US20130252941A1,O=Cc1cnccc1Cl.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1ccncc1C=O,,CN(C)C=O,,CCOC(C)=O,,val
+US08318928B2,CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)O)cccc1OC(F)F.Nc1nc2c(s1)CCC2>>CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)Nc2nc3c(s2)CCC3)cccc1OC(F)F,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,val
+US20100105655A1,C1COCCN1.COc1cc(N2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COc1cc(N2CCN(C(=O)N3CCOCC3)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,val
+US06239151B1,CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)[C@H](N)CO)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1.Cc1ccc(S(=O)(=O)O)cc1>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)[C@H](N)CO)[C@H](C/C=C/c1ccccc1)C(=O)NO.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,val
+US05574142,CC(=O)OC[C@H]1OC(Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O.N=C(N)S.O=C(O)CCI>>CC(=O)OC[C@H]1O[C@@H](SCCC(=O)O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O,,CC(C)=O,,,,val
+US20080113073A1,COc1cc(CC(=O)O)ccc1O.COc1cccc(O)c1>>COc1ccc(C(=O)Cc2ccc(O)c(OC)c2)c(O)c1,,CCOCC,,CC(=O)[O-].[Na+],,val
+US20060183762A1,CC1OC12CCN(C(=O)OCc1ccccc1)C2.F>>CC(O)C1(F)CCN(C(=O)OCc2ccccc2)C1,,ClCCl,,c1ccncc1,,val
+US06057337,CCCCCCCCCCCCCCCCCC(=O)N1CCCCC1CCON(C=O)CCCN1CCOCC1.Cl>>CCCCCCCCCCCCCCCCCC(=O)N1CCCCC1CCON(C=O)CCCN1CCOCC1.Cl,,CCOC(C)=O,,,,val
+US20040132727A1,COc1cc2nccc(Oc3ccc(NC(=O)CCOc4ccccc4)c(C)c3C)c2cc1OC>>COc1cc2nccc(Oc3ccc(NCCCOc4ccccc4)c(C)c3C)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],val
+US20050059687A1,BrBr.CCc1nc2ccccc2c(=O)[nH]1>>CC(Br)c1nc2ccccc2c(=O)[nH]1,,CC(=O)O,,O,,val
+US20060035844A1,CC(=O)OC[C@H]1O[C@H](OC(=N)C(Cl)(Cl)Cl)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.COC(=O)Oc1cc(C)c(Cc2ccc([N+](=O)[O-])cc2)c(O)c1>>COC(=O)Oc1cc(C)c(Cc2ccc([N+](=O)[O-])cc2)c(O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)c1,,ClCCl,,O,,val
+US20100286126A1,CC(C)(C)OC(=O)N[C@@H]1CCN(C(=O)CN2CCC(O)CC2)C1.O=C=Nc1ccccc1-c1ccccc1>>CC(C)(C)OC(=O)N[C@@H]1CCN(C(=O)CN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)C1,,CN1CCCC1=O,,,,val
+US20120190649A1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C#N)ccc3c2)CC1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(CN)ccc3c2)CC1,[Ni],CO,,[NH4+].[OH-],,val
+US20020064735A1,Nc1cc(Cl)c([N+](=O)[O-])cc1O.O=C(Cl)c1ccc(F)c(F)c1>>O=C(Nc1cc(Cl)c([N+](=O)[O-])cc1O)c1ccc(F)c(F)c1,,CCOC(C)=O,,,,val
+US04585789,BrCc1ccccc1.OCCCC=Cc1ccccc1>>C(=Cc1ccccc1)CCCOCc1ccccc1,,C1CCOC1,,[H-].[Na+],,val
+US06028116,COc1ccc2c(c1)C(CC(=O)Cl)=C(C)/C2=C/c1ccc(SC)cc1>>COc1ccc2c(c1)C(CCO)=C(C)/C2=C/c1ccc(SC)cc1,,C1CCOC1,,[BH4-].[Li+],,val
+US20080200471A1,CC(C)(C)C(=O)Cl.Nc1cccc(O)c1>>CC(C)(C)C(=O)Nc1cccc(O)c1,,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],,val
+US20110015238A1,CC(C)(C)[Si](C)(C)OC[C@H]1CCC(=O)N1Cc1nc(/C=C/C(=O)O)cs1.CCCCI>>CCCCOC(=O)/C=C/c1csc(CN2C(=O)CC[C@@H]2CO[Si](C)(C)C(C)(C)C)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],val
+US20080188528A1,CCOC(=O)c1ccc[nH]c1=O.COc1cc2ccccc2cc1CBr>>CCOC(=O)c1cccn(Cc2cc3ccccc3cc2OC)c1=O,,CN(C)C=O,,Cl,[H-].[Na+],val
+US04966905,CC1=CC(=O)C(C)(C)O1.O=Cc1ccc(Cl)cc1Cl>>CC1(C)OC(C=Cc2ccc(Cl)cc2Cl)=CC1=O,,CCO,,[Na+].[OH-],,val
+US20090318436A1,Fc1cc(-c2ccc(Cl)cn2)cnc1F.NN>>NNc1ncc(-c2ccc(Cl)cn2)cc1F,,CC(C)O,O,,,val
+US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(NC(=O)OC(C)(C)C)nc3)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(N)nc3)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20120010188A1,Nc1ncccn1.O=C(CCl)c1ccc(Cl)cc1Cl>>Clc1ccc(-c2cn3cccnc3n2)c(Cl)c1,,CCO,,[Na+].[OH-],,val
+US04929741,C#CCOC(C)OCC.O=Cc1ccc(F)cc1>>CCOC(C)OCC#CC(O)c1ccc(F)cc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],val
+US04409229,CN1CCC2(CC1)SC(c1ccccc1Cl)c1ccccc12.O=C(Cl)Oc1ccccc1>>O=C(Oc1ccccc1)N1CCC2(CC1)SC(c1ccccc1Cl)c1ccccc12,,ClCCl,,,,val
+US05665718,C=CCBr.CCN(C(C)C)C(C)C.ClCCl.NCc1noc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)n1>>C=CCN(CC=C)Cc1noc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)n1,,ClCCl,,,,val
+US20040122029A1,COC(=O)C(Cc1cnc(Nc2ccccc2)nc1Nc1ccccc1)c1ccccc1>>O=C1C(c2ccccc2)Cc2cnc(Nc3ccccc3)nc2N1c1ccccc1,,CC(=O)O,CCOC(C)=O,O=S(=O)(O)O,,val
+US05049669,CCC(C)CNC(=O)c1ccc2c(c1)N(C(C)CN(CC)CC)c1ccccc1S2.O=C(O)/C=C/C(=O)O>>CCC(C)CNC(=O)c1ccc2c(c1)Nc1ccccc1S2.O=C(O)/C=C/C(=O)O,,CC(C)O,,,,val
+US20100216986A1,CC(C)[Si](Oc1ccc(-c2ccc(CO)[se]2)cc1)(C(C)C)C(C)C>>OCc1ccc(-c2ccc(O)cc2)[se]1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],val
+US20140314669A1,CC(C)(C)OC(=O)N1CCC(CCC(=O)N2CCC[C@@H](C(=O)O)C2)CC1.COC(=O)CC(N)c1cncc(Br)c1>>COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(Br)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US06063789,Cl.NC1=NC(c2ccncc2)Cc2ccccc21>>Cl.NC1=NC(C2CCNCC2)Cc2ccccc21,O=[Pt],CO,Cl,[H][H],,val
+US20110098320A1,C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)C(=O)C1.Cn1cc(Br)ccc1=O>>C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(-c3ccc(=O)n(C)c3)cc2)C(=O)C1,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20060229349A1,CC(C)N1C(=O)Cc2cc(N3CC(CN)OC3=O)cc(F)c21.COC(=O)Cl>>COC(=O)NC[C@H]1CN(c2cc(F)c3c(c2)CC(=O)N3C(C)C)C(=O)O1,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US20010039344A1,O=C(O)c1ccc(CBr)cc1.[C-]#N>>N#CCc1ccc(C(=O)O)cc1,,CC#N,O,[Na+].[OH-],,val
+US20120283297A1,CC(C)Oc1ccc(-c2nc(-c3cccc4[nH]ncc34)no2)cc1Cl.COC(=O)C(C)CBr>>COC(=O)C(C)Cn1ncc2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20030055085A1,N#Cc1cc(F)cc(C(=O)O)c1.O=C(Cl)C(=O)Cl>>N#Cc1cc(F)cc(C(=O)Cl)c1,,CN(C)C=O,,,,val
+US20040180896A1,Cn1nc(C(C)(C)C)cc1NC(=O)OCC(F)(F)F.NCc1cc(F)ccc1Oc1ccc2c(CN3CCCC3)noc2c1>>Cn1nc(C(C)(C)C)cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2c(CN3CCCC3)noc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,val
+US06369063B1,COC(=O)CN1CCN[C@@H](CCC(=N)NCNS(=O)(=O)c2ccc(C)cc2)C1=O.O=S(=O)(Cl)Cc1ccccc1>>COC(=O)CN1CCN(S(=O)(=O)Cc2ccccc2)[C@@H](CCC(=N)NCNS(=O)(=O)c2ccc(C)cc2)C1=O,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US20100152160A1,CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)cc3)CC2)Oc2cc(O)c(Cl)cc21.FC(F)Cl>>CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)cc3)CC2)Oc2cc(OC(F)F)c(Cl)cc21,,C1CCOC1,,CC(C)(C)[O-].[K+],,val
+US20140148466A1,CC(C)(C)C(N)C(=O)c1ccc(C#N)cc1.Cc1cccc(N2CCNCC2)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cccc(N2CCN(C(=O)NC(C(=O)c3ccc(C#N)cc3)C(C)(C)C)CC2)n1,,ClCCl,,Cl,,val
+US20110190342A1,Cc1cccc(Oc2ccc(C[C@H](N)C(=O)O)cc2)n1.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>Cc1cccc(Oc2ccc(C[C@H](Nc3nc4ccc(Cl)cc4cc3C(=O)O)C(=O)O)cc2)n1,,CS(C)=O,,,,val
+US05130309,CCN1CC(Oc2ccc([N+](=O)[O-])cc2)C1>>CCN1CC(Oc2ccc(N)cc2)C1,[Pd],CCO,,,,val
+US20090298744A1,CCCn1c(=O)c2[nH]c(-c3cnn(CC(=O)Cl)c3)nc2n(CCC)c1=O.FC(F)(F)c1cccc(N2CCNCC2)c1>>CCCn1c(=O)c2[nH]c(-c3cnn(CC(=O)N4CCN(c5cccc(C(F)(F)F)c5)CC4)c3)nc2n(CCC)c1=O,,C1CCOC1,,,,val
+US20090137609A1,CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2cccc([C@@H](O)C(=O)OC)c2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2cccc([C@@H](O)C(=O)O)c2)c(C)c1,,CO,,Cl,[Na+].[OH-],val
+US20150210630A1,CCON=C(CNC(=O)c1ccccc1C(F)(F)F)c1ncc(Cl)cc1Cl>>CCO/N=C(/CNC(=O)c1ccccc1C(F)(F)F)c1ncc(Cl)cc1Cl,,CC#N,,,,val
+US05426119,CCNCC.O=C(O)CCCC=C(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1>>CCN(CC)C(=O)CCCC=C(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,val
+US03932644,CC1NC(=S)NC1=O.CI>>CSC1=NC(=O)C(C)N1.I,,CCO,,,,val
+US20090286778A1,CC(C)(C)OC(=O)Nc1ccnc(C#Cc2cccc(N)c2)c1>>CC(C)(C)OC(=O)Nc1ccnc(/C=C\c2cccc(N)c2)c1,[Pd],CO,,,,val
+US20120059030A1,CI.COc1cc(-c2nnc3n2CCCC3(CO)Cc2ccc(F)c(F)c2)ccc1-c1cnc(C)o1>>COCC1(Cc2ccc(F)c(F)c2)CCCn2c(-c3ccc(-c4cnc(C)o4)c(OC)c3)nnc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,val
+US20160122342A1,COc1nc(C)cc(CO)c1C#N.CS(=O)(=O)Cl>>COc1nc(C)cc(COS(C)(=O)=O)c1C#N,,ClCCl,,CCN(CC)CC,,val
+US20070027112A1,CNOC.O=C(Cl)c1ccc(-c2ccccc2)cc1>>CON(C)C(=O)c1ccc(-c2ccccc2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,val
+US20150259295A1,COC(=O)c1c(Br)cnn1C.OB(O)c1ccccc1>>COC(=O)c1c(-c2ccccc2)cnn1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20070213283A1,CCOC(=O)c1cn(CC)c2nc(Cl)c(F)cc2c1=O>>CCOC(=O)c1cn(CC)c2ncc(F)cc2c1=O,[Pd],CCO,,CCN(CC)CC,,val
+US20020156081A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(N2CCC(n3nc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1,,ClCCCl,O,CC(=O)O,O=C([O-])O.[Na+],val
+US20080200338A1,C=CC=O.CCOC(=O)CNC(=O)c1cn(C)nc1C(F)(F)F>>C=CC(O)C(NC(=O)c1cn(C)nc1C(F)(F)F)C(=O)OCC,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],val
+US04242519,COC(=O)C(C)(SC)c1cccc(C2(c3ccccc3)OCCO2)c1>>COC(=O)C(C)(SC)c1cccc(C(=O)c2ccccc2)c1,,O,,CO,Cl,val
+US20060257987A1,CCOC(=O)CSc1ccc(OCC[C@H](C)OS(C)(=O)=O)cc1C.CCc1ccc(O)c(Oc2ccccc2)c1>>CCOC(=O)CSc1ccc(OCCC(C)Oc2ccc(CC)cc2Oc2ccccc2)cc1C,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],val
+US20130231358A1,COC(=O)c1ccc(CBr)c(CBr)c1.O=C1Cc2c(Cl)ncnc2N1>>COC(=O)c1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncnc(Cl)c21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],val
+US20100143341A1,COc1cc(C(=O)Cl)ccc1[N+](=O)[O-].N>>COc1cc(C(N)=O)ccc1[N+](=O)[O-],,C1CCOC1,CCOC(C)=O,C1COCCO1,,val
+US20130072677A1,C1CNCCOC1.CCOC(=O)c1ccc(C#Cc2ccc(C=O)cc2)cc1>>CCOC(=O)c1ccc(C#Cc2ccc(CN3CCCOCC3)cc2)cc1,,CC(=O)O,ClC(Cl)Cl,Cl,O=C([O-])O.[Na+],val
+US20040092518A1,CCC(C=Cc1cccc(OCc2c(C)cccc2C)c1)C(=O)O>>Cc1cccc(C)c1COc1cccc(C=CCC(=O)O)c1,,CCO,,[Na+].[OH-],,val
+US20090163524A1,O=C1NC(=O)c2ccccc21.OC(Cc1nccn1C(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1>>O=C1c2ccccc2C(=O)N1C(Cc1nccn1C(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,val
+US20140057909A1,CC(C)N(NC(=O)c1ccccc1)C(=O)/C=C/c1c[nH]c2ccccc12.O=C(Cl)c1ccccc1>>CC(C)N(NC(=O)c1ccccc1)C(=O)/C=C/c1cn(C(=O)c2ccccc2)c2ccccc12,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,val
+US20130029961A1,CNCCO.O=[N+]([O-])c1ccc(Cl)nc1>>CN(CCO)c1ccc([N+](=O)[O-])cn1,,O,,,,val
+US20080262048A1,Nc1ccc(Cl)cc1C=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F,,ClCCl,ClCCl,CCN(CC)CC,,val
+US20140005172A1,CC(C)(C)OC(=O)N1CCOc2ccc(B(O)O)cc2C1.Nc1ncc(Br)cc1S(N)(=O)=O>>CC(C)(C)OC(=O)N1CCOc2ccc(-c3cnc(N)c(S(N)(=O)=O)c3)cc2C1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,val
+US20060094724A1,CC(C)(C)OC(=O)NCC=O.COC(=O)[C@@H]1CC[C@@H](N)CC1>>COC(=O)[C@@H]1CC[C@@H](NCCNC(=O)OC(C)(C)C)CC1,,CCN(CC)CC,ClCCl,Cl,O=C([O-])O.[Na+],val
+US20150065468A1,COC(=O)C(OC)OC.COc1cc([N+](=O)[O-])c(N)cc1OCc1ccccc1>>COc1cc([N+](=O)[O-])c(NC(=O)C(OC)OC)cc1OCc1ccccc1,,CS(C)=O,,[H-].[Na+],,val
+US20100173880A1,Nc1ccccc1.O=C(O)C(Br)c1ccc(Cl)cc1>>O=C(O)C(Nc1ccccc1)c1ccc(Cl)cc1,,CC#N,,,,val
+US20120184574A1,BrBr.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(F)c(OC(F)F)cc3n2C2CCC2)nc1)C(F)(F)F>>C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3c(Br)c(F)c(OC(F)F)cc3n2C2CCC2)nc1)C(F)(F)F,[Fe],ClCCCl,,O=S([O-])O.[Na+],,val
+US20030220350A1,CC(C)N1C(=O)c2ccc([N+](=O)[O-])cc2C1=O>>CC(C)N1C(=O)c2ccc(N)cc2C1=O,[Pd],C1CCOC1,CN(C)C=O,,,val
+US20120029002A1,Nc1nc(-n2nc(Sc3ccccc3F)c3ccccc32)nc(N)c1[N+](=O)[O-]>>Nc1nc(-n2nc(Sc3ccccc3F)c3ccccc32)nc(N)c1N,[Pd],c1ccncc1,,,,val
+US20160207926A1,NCC(F)(F)F.O=[N+]([O-])c1c(Cl)ncnc1Cl>>O=[N+]([O-])c1c(Cl)ncnc1NCC(F)(F)F,,C1CCOC1,,,,val
+US20160122342A1,C=CCc1c(C(=O)NCc2c(CN(C)CC=C)cc(C)nc2OC)cccc1N(CC)C1CCOCC1>>CCN(c1cccc2c1CC=CCN(C)Cc1cc(C)nc(OC)c1CNC2=O)C1CCOCC1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,,,val
+US20080058320A1,COCCCc1cn(C)c2ccc(CC(CC(NC(=O)OC(C)(C)C)C3CO3)C(C)C)cc12.O=C1CCCCN1>>COCCCc1cn(C)c2ccc(CC(CC3NC(=O)OC3CN3CCCCC3=O)C(C)C)cc12,,CS(C)=O,,CC(C)(C)[O-].[K+],,val
+US20150344481A1,Fc1ccc(-c2cn3c(n2)COCC3)cc1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2nc3n(c2Br)CCOC3)cc1,,ClCCl,,,,val
+US20130072519A1,C=O.CCOC(=O)C1c2ccccc2C(=O)N1C>>CCOC(=O)C1(CO)c2ccccc2C(=O)N1C,,C1COCCO1,,C1CCC2=NCCCN2CC1,,val
+US20060264415A1,CC(C)(C)OC(=O)N1CCC(CCCCO)C1.II>>CC(C)(C)OC(=O)N1CCC(CCCCI)C1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,val
+US06689909B1,CC(=O)Nc1c(Sc2ccc(F)cc2)ccc(N)c1Cl.C[C@@](O[Si](C)(C)C)(C(=O)Cl)C(F)(F)F>>CC(=O)Nc1c(Sc2ccc(F)cc2)ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c1Cl,,CCN(CC)CC,ClCCl,,,val
+US04602027,CCOC(=O)C(N)C(C)=O.O=C(Cl)C=Cc1ccccc1>>CCOC(=O)C(NC(=O)C=Cc1ccccc1)C(C)=O,,ClC(Cl)Cl,,CCN(CC)CC,Cl,val
+US20150209445A1,CC#N.CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1.CCN(C(C)C)C(C)C.CN(C)C=O.O=C(O)C(F)(F)F.O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1>>CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)N(C)CCN(C)C(=O)OC(C)(C)C)cc1,,CC#N,O,,,val
+US20150018363A1,Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4csc(Br)n4)cc3=O)cc21.OB(O)C1CC1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4csc(C5CC5)n4)cc3=O)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],val
+US20150065507A1,CC(C)c1ccc(N(CC2COC2)S(=O)(=O)c2ccc(F)cc2)nc1.OCC1CCOCC1>>CC(C)c1ccc(N(CC2COC2)S(=O)(=O)c2ccc(OCC3CCOCC3)cc2)nc1,,CS(C)=O,,[H-].[Na+],,val
+US20040138251A1,COc1cc(N)c(Cl)cc1Cl.Cc1cc2c(Cl)c(C#N)cnc2s1>>COc1cc(Nc2c(C#N)cnc3sc(C)cc23)c(Cl)cc1Cl,,C1CCOC1,,[H-].[Na+],,val
+US06204277B1,CCOC(C)=O.Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(O)C(N)=O)cc1>>COC(=O)OC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(N)=O,,C1CCOC1,ClCCl,CCN(CC)CC,,val
+US20100056502A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCNCC1.O=CC1CCn2c(=O)sc3ccc(F)c1c32>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CC2CCn3c(=O)sc4ccc(F)c2c43)CC1,,CCOC(C)=O,,,,val
+US20120010228A1,CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(CCCCCC(=O)OCc1ccccc1)CN2c1ccccc1>>O=C(CCCCCN1CN(c2ccccc2)C2(CCNCC2)C1=O)OCc1ccccc1,,C1COCCO1,,Cl,,val
+US05120874,BrCc1ccccc1.O=C(c1ccccc1)C(O)Cc1cccc(O)c1>>O=C(c1ccccc1)C(O)Cc1cccc(OCc2ccccc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US20150183781A1,Cn1cc(-c2cnc3[nH]ccc3c2)cn1.O=C1CCC(=O)N1I>>Cn1cc(-c2cnc3[nH]cc(I)c3c2)cn1,,CC(C)=O,,,,val
+US20140350019A1,CCOC(=O)CBr.Cc1c(O)ccc(F)c1NCc1cc(-c2cccc(F)c2)ccc1F>>CCOC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],val
+US04730008,ClCCOCCCl.Nc1ccc(CCCCO)cc1>>OCCCCc1ccc(N2CCOCC2)cc1,,CN(C)C=O,,[I-].[K+],,val
+US20160016948A1,CC(C)n1cnc2cnc(Nc3ccnc(C4=CCN(C(=O)OC(C)(C)C)CC4)n3)cc21>>CC(C)n1cnc2cnc(Nc3ccnc(C4CCN(C(=O)OC(C)(C)C)CC4)n3)cc21,[Pd],CCOC(C)=O,CO,,,val
+US03981905,CCOC(=O)C(C)(C(=O)[O-])c1ccc(Oc2ccc(F)cc2)cc1>>CC(C(=O)O)c1ccc(Oc2ccc(F)cc2)cc1,,CCO,,[Na+].[OH-],,val
+US20160136172A1,ClCI.O=C(NCc1ccc(F)cc1)c1nc(Br)ccc1O>>O=C1c2nc(Br)ccc2OCN1Cc1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20100022613A1,CN(C)C=O.Fc1ccc(CSc2cccc(Br)c2)cc1>>O=Cc1cccc(SCc2ccc(F)cc2)c1,,C1CCOC1,,[Li]CCCC,,val
+US20030199550A1,CNC[C@@H]1CC[C@@H](CO)CC1.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>CN(C[C@@H]1CC[C@@H](CO)CC1)C(=O)OCc1ccccc1,,CO,,,,val
+US04409236,COC(=O)c1ccc(CN2CC2C#N)s1>>N#CC1CN1Cc1ccc(C(=O)O)s1,,CC(C)=O,,[Na+].[OH-],,val
+US20020082426A1,CC(C)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N1CC(=O)C(OCC(=O)OC(C)(C)C)C1>>CC(C)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N1CC(=O)C(OCC(=O)O)C1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20020137961A1,CC(C)(C)[Si](C)(C)Oc1ccc([C@@H]2CC[C@@H](O)CC2)c(O[Si](C)(C)C(C)(C)C)c1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)O[C@@H]1CC[C@@H](c2ccc(O)cc2O)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,val
+US20050038101A1,CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2cc3cc(N)ccc3n2Cc2ccccc2F)cc1.O=C(O)CC1CCCO1>>CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2cc3cc(NC(=O)CC4CCCO4)ccc3n2Cc2ccccc2F)cc1,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,val
+US20040092546A1,C[C@H](N)c1ccccc1.O=C(Cl)c1ccc[nH]1>>C[C@H](NC(=O)c1ccc[nH]1)c1ccccc1,,ClCCl,,CCN(CC)CC,,val
+US20130059834A1,CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C1CNC1.CS(=O)(=O)Cl>>CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C1CN(S(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,Cl,val
+US05736284,CCO[PH]([O-])(OCC)C(c1ccccc1)c1ccccc1.CCn1c2ccccc2c2cc(C=O)ccc21>>CCn1c2ccccc2c2cc(C=C(c3ccccc3)c3ccccc3)ccc21,,CN(C)C=O,,CC(C)(C)[O-].[K+],,val
+US06127386,CC(C)(C)OC(=O)N1CC[C@H]1COc1cnc(Cl)c(Br)c1.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2cc(OC[C@@H]3CCN3)cnc2Cl)cc1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,val
+US20160016948A1,CC(C)(C)OC(=O)N1CCC(O)C(C)(F)C1.Cl>>CC1(F)CNCCC1O.Cl,,CCOCC,,,,val
+US06162832,CCOc1ccc(Oc2ccc(O)cc2)c(N)c1.Fc1ccc(F)c(CBr)c1>>CCOc1ccc(Oc2ccc(OCc3cc(F)ccc3F)cc2)c(N)c1,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],val
+US20090209597A1,O=Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(CO)c1,,CO,,[BH4-].[Na+],,val
+US04450165,CNCc1ccccc1.O=C(CBr)c1ccco1>>CN(Cc1ccccc1)CC(O)c1ccco1,,CO,,O=C([O-])[O-].[K+].[K+],,val
+US20050124623A1,CCOC(=O)c1c[nH]c2c(Cl)ncnc12>>O=C(O)c1c[nH]c2c(Cl)ncnc12,,C1CCOC1,O,[Li]O,,val
+US07635779B2,O=c1cc(-c2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)oc2cc(OCC3CO3)ccc12.c1ccc(N2CCNCC2)cc1>>O=c1cc(-c2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)oc2cc(OCC(O)CN3CCN(c4ccccc4)CC3)ccc12,,CO,,,,val
+US20140243336A1,NN.O=C(CCCCl)C(Br)CBr>>ClCCCc1cc[nH]n1,,CC(C)O,,O,,val
+US06255327B1,Cc1nc(-c2ccccc2)nn1-c1ccccc1OCc1ccccc1>>Cc1nc(-c2ccccc2)nn1-c1ccccc1O,,ClCCl,,BrB(Br)Br,,val
+US05270308,CC1(C)N=C(c2ccccn2)c2cc(C#N)ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)N=C(c2cccc[n+]2[O-])c2cc(C#N)ccc2O1,,ClCCl,,,,val
+US20040058820A1,O=C(O)C(Oc1ccc(Cl)cc1)c1ccc(Cl)cc1>>OCC(Oc1ccc(Cl)cc1)c1ccc(Cl)cc1,,C1CCOC1,,B,,val
+US04232035,CN(SSc1ccccc1)C(=O)F.CN1C(=O)C(C)(C)SC1=NO>>CN(SSc1ccccc1)C(=O)ON=C1SC(C)(C)C(=O)N1C,,C1COCCO1,,CCN(CC)CC,,val
+US20140128611A1,COC(=O)C1(Cc2ccc(Cl)cc2)CCC(C)(CO)C1=O.CS(=O)(=O)Cl>>COC(=O)C1(Cc2ccc(Cl)cc2)CCC(C)(COS(C)(=O)=O)C1=O,,ClCCl,,CCN(CC)CC,O,val
+US20100152193A1,CN(C)/C=C/C(=O)c1nn(-c2ccc(OC(F)(F)F)cc2)ccc1=O.N#Cc1cccc(NN)c1>>N#Cc1cccc(-n2nccc2-c2nn(-c3ccc(OC(F)(F)F)cc3)ccc2=O)c1,,CCO,,,,val
+US07868205B2,NCCN1CCOCC1.O=C(O)c1ccc2c(c1)C(=O)OC2=O>>O=C(O)c1ccc2c(c1)C(=O)N(CCN1CCOCC1)C2=O,,CC(=O)O,,,,val
+US20160272592A1,COCc1ccc(C2CCC2)c(CN)c1.Cc1c(OC[C@H]2COC(C)(C)O2)nn(-c2ccccc2)c1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COCc1ccc(C2CCC2)c(CNC(=O)Nc2c(C)c(OC[C@H]3COC(C)(C)O3)nn2-c2ccccc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US06002008,CCCI.CCOC(C)=O.CN(C)C=O.N#Cc1cnc2cc(O)c(O)cc2c1Nc1cccc(Br)c1>>CCCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OCCC,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],val
+US20090093483A1,COC(=O)C(C)(C)c1ccc(C(F)(F)F)cc1>>CC(C)(C(=O)O)c1ccc(C(F)(F)F)cc1,,CO,O,[K+].[OH-],,val
+US05547972,CC(=O)Cl.CCC(CC)(NCCCn1cnc(CO)c1)c1ccccc1.ClCCl>>CCC(CC)(NCCCn1cnc(COC(C)=O)c1)c1ccccc1.Cl,,ClCCl,,CCN(CC)CC,,val
+US05296495,COC(=O)C(C)(C)Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1>>CC(C)(Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)C(=O)O,,CO,,[Na+].[OH-],,val
+US20140256729A1,CCOC(=O)[C@@H]1C[C@H]1c1cncs1>>O=C(O)[C@@H]1C[C@H]1c1cncs1,,CO,,[Na+].[OH-],,val
+US20130090386A1,N[C@@H]1C[C@H]1c1ccc(OCc2cccc(Br)c2)cc1.O=CCC1CCCCC1>>Brc1cccc(COc2ccc([C@@H]3C[C@H]3NCCC3CCCCC3)cc2)c1,,ClCCCl,,[BH4-].[Na+],,val
+US20050090559A1,COc1ccc(F)cc1C(C)(C)CC(O)(C=O)C(F)(F)F.Cc1ncc2c(N)cccc2n1>>COc1ccc(F)cc1C(C)(C)CC(O)(C=Nc1cccc2nc(C)ncc12)C(F)(F)F,,CC(Cl)Cl,,,,val
+US20100324092A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1NC(=O)c1ccc(CN)cc1,[Pd],CCO,,O=CO,,val
+US20090082356A1,Clc1nc2ccccc2nc1Cl.NS(=O)(=O)c1cccc(F)c1>>O=S(=O)(Nc1nc2ccccc2nc1Cl)c1cccc(F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20130289033A1,Cc1cccc(C)c1B(O)O.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(I)cc1>>Cc1cccc(C)c1-c1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,val
+US20120285538A1,CCCCC1(CCCC)c2cc(N)ccc2-c2ccc(Br)cc21.ICCCCCI>>CCCCC1(CCCC)c2cc(Br)ccc2-c2ccc(N3CCCCC3)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20070082923A1,CCCCCCCCCCCCSC(=Cc1ccc(Cl)cc1)CO.CO>>O=C(CO)Cc1ccc(Cl)cc1,,CCCCCCC,,O=S(=O)(O)O,,val
+US20140066424A1,C=C[Sn](CCCC)(CCCC)CCCC.Cc1nc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1cccc(Br)c1>>C=Cc1cccc(Cn2nc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)nc2C)c1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,val
+US20050250760A1,CCN1CCN(C(=O)c2cn(CC3CCCCC3)c3c(O)cccc23)CC1.FCCBr>>CCN1CCN(C(=O)c2cn(CC3CCCCC3)c3c(OCCF)cccc23)CC1,,CN(C)C=O,,[H-].[Na+],,val
+US20030092720A1,CC(=O)Nc1cc(C(=O)Nc2nc(C(C)(C)C)cs2)ccn1>>CC(C)(C)c1csc(NC(=O)c2ccnc(N)c2)n1,,CCO,,Cl,,val
+US20050065210A1,CC(O[C@@H]1CC[C@@H](N(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1)C(=O)OC(C)(C)C>>CC(O[C@@H]1CC[C@@H](N(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,val
+US04166128,COC(=O)C(O)c1ccccc1Nc1c(Cl)cccc1Cl>>O=C(O)C(O)c1ccccc1Nc1c(Cl)cccc1Cl,,CCO,,[Na+].[OH-],,val
+US20140288081A1,N#CBr.Nc1c(S)cccc1S(=O)(=O)Nc1ccc(C(=O)O)cc1>>Nc1nc2c(S(=O)(=O)Nc3ccc(C(=O)O)cc3)cccc2s1,,C1CCOC1,,,,val
+US03952001,CCCSc1nc[nH]n1.CCN(CC)C(=O)Cl>>CCCSc1ncn(C(=O)N(CC)CC)n1,,CCN(CC)CC,,C1CCOC1,,val
+US20090029965A1,CC(N)=S.O=C1c2ccccc2N(C(=O)c2ccccc2)CCC1Br>>Cc1nc2c(s1)CCN(C(=O)c1ccccc1)c1ccccc1-2,,CCO,,,,val
+US05300479,COC(=O)c1cc(NC(C)=O)c([N+](=O)[O-])cc1C(=O)OC.Cc1ccc(S(=O)(=O)O)cc1>>COC(=O)c1cc2nc(C)[nH]c2cc1C(=O)OC.Cc1ccc(S(=O)(=O)O)cc1,[Pt],Cc1ccccc1,,CO,,val
+US04228183,CSCC[C@H](NC(C)=O)C(=O)O.NCCc1ccc(O)c(O)c1>>CSCC[C@H](NC(C)=O)C(=O)NCCc1ccc(O)c(O)c1,,CN(C)C=O,,CCN(CC)CC,Cl,val
+US20140206663A1,CCOC(=O)C(C)N1C(=O)COc2cc(F)c(Br)cc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)C(C)N1C(=S)COc2cc(F)c(Br)cc21,,Cc1ccccc1,,,,val
+US20150031679A1,COC(=O)c1ccc2c(c1)nc(Cl)c(=O)n2Cc1ccccc1.C[C@H]1CCCN1>>COC(=O)c1ccc2c(c1)nc(N1CCC[C@@H]1C)c(=O)n2Cc1ccccc1,,CS(C)=O,,,,val
+US20080125425A1,CCCn1c(=O)c2[nH]c(-c3ccc(Cl)nc3)cc2n(CCC)c1=O.NCC1CCCO1>>CCCn1c(=O)c2[nH]c(-c3ccc(NCC4CCCO4)nc3)cc2n(CCC)c1=O,,CCO,,,,val
+US20050107388A1,N#Cc1ccc(C(F)(F)F)cc1[N+](=O)[O-].OCCN1CCOCC1>>N#Cc1ccc(C(F)(F)F)cc1OCCN1CCOCC1,,CN(C)C=O,O,[K+].[OH-],,val
+US20110178132A1,N#Cc1cc(Cl)ccn1.OB(O)c1ccccc1OC(F)(F)F>>N#Cc1cc(-c2ccccc2OC(F)(F)F)ccn1,,C1COCCO1,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],val
+US20060223829A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCNCC1>>CC(=O)N1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,,,val
+US20090247526A1,CC(C)(C)OC(=O)N1CCc2ncnc(Sc3cc(Nc4nc(CCc5ccccc5)cs4)ncc3Br)c2C1>>Brc1cnc(Nc2nc(CCc3ccccc3)cs2)cc1Sc1ncnc2c1CNCC2,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,val
+US20100105679A1,ClCCN1CCOCC1.O=c1cc(OCc2ccccc2)ccn1-c1ccc2[nH]ncc2c1>>O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCN2CCOCC2)c1,,CS(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20070219212A1,CC1=NCN(CCl)S1.CN1CCCC1=O.COC(=O)C[C@H]1OCCc2c1[nH]c1c(C)c(O)cc(C#N)c21>>CCC[C@]1(CC(=O)OC)OCCc2c1[nH]c1c(C)c(OCc3nnc(C)s3)cc(C#N)c21,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,val
+US20080214641A1,CCOC(=O)C(C)(F)F.COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)N)c1>>COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)NC(=O)C(C)(F)F)c1,,CC#N,,,,val
+US20120028973A1,COC(=O)/C=C/c1ccc(-c2ccc(OC(F)(F)F)cc2)cc1>>OC/C=C/c1ccc(-c2ccc(OC(F)(F)F)cc2)cc1,,Cc1ccccc1,ClCCl,CC(C)C[AlH]CC(C)C,,val
+US20100305096A1,CN(C)C1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1.c1ccc2[nH]cnc2c1>>CN(C)C1CCN(Cc2cc3nc(-n4cnc5ccccc54)nc(N4CCOCC4)c3s2)CC1,,C1COCCO1,,Cl,,val
+US20070037808A1,CCCCOC(=O)N(Cc1ccc(OC)cc1)S(=O)(=O)NCC(=O)OCC>>CCOC(=O)CNS(=O)(=O)NCc1ccc(OC)cc1,,CO,,Cl,,val
+US20130172384A1,COc1cc(F)c(B(O)O)cc1F.Cn1nc(-c2ccc(Br)cc2F)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O>>COc1cc(F)c(-c2ccc(-c3nn(C)c(=O)n3C[C@@H]3CCN(C(=O)C4CC4)C3)c(F)c2)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],val
+US20120302549A1,N#CN[C@]1(C(F)(F)CO)CCc2ccc([N+](=O)[O-])cc21>>NC1=N[C@@]2(CCc3ccc([N+](=O)[O-])cc32)C(F)(F)CO1,,CO,,[NH4+].[OH-],,val
+US20040229900A1,O=C=Nc1ccccc1.c1ccc(CN2CC3CNCC(C3)C2)cc1>>O=C(Nc1ccccc1)N1CC2CC(CN(Cc3ccccc3)C2)C1,,ClCCl,,,,val
+US20140179902A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)CCCCCCC(=O)ON1C(=O)CCC1=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CC(C)(C)OC(=O)CN(CCCC[C@H](N)C(=O)O)Cc1ccccn1>>CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)CCCCCCC(=O)N[C@@H](CCCCN(CC(=O)OC(C)(C)C)Cc1ccccn1)C(=O)O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,val
+US05629325,C#Cc1ccccc1.CN1CCC[C@H]1COc1cncc(Br)c1.ClCCl>>CN1CCC[C@H]1COc1cncc(C#Cc2ccccc2)c1.Cl.Cl,[Cu]I,,,CCN(CC)CC,,val
+US20030125370A1,CC(=O)N1CCN(Cc2c(C)[nH]c(C=O)c2C)CC1.O=C1Cc2cc(S(=O)(=O)Cc3c(Cl)cccc3Cl)ccc2N1>>CC(=O)N1CCN(Cc2c(C)[nH]c(/C=C3\C(=O)Nc4ccc(S(=O)(=O)Cc5c(Cl)cccc5Cl)cc43)c2C)CC1,C1CCNCC1,CCO,,,,val
+US20140024650A1,CCOC(=O)C1CCCCC1N.CCS(=O)(=O)Cl>>CCOC(=O)[C@@H]1CCCC[C@H]1NS(=O)(=O)CC,,CCN(CC)CC,,Cl,,val
+US20110082133A1,CC(C)(C)OC(=O)c1ccc(CCn2c(CBr)c(Cl)cc(Cl)c2=O)cc1.CNc1ncc(C)s1>>Cc1cnc(N(C)Cc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)OC(C)(C)C)cc2)s1,,CCOC(C)=O,O,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],val
+US07618996B2,CC(C)(C)OC(=O)N(CCC1CC1)Cc1ccc(Oc2ccc3c(c2)OC(C)(C)OC3=O)c(F)c1.N>>CC(C)(C)OC(=O)N(CCC1CC1)Cc1ccc(Oc2ccc(C(N)=O)c(O)c2)c(F)c1,,CC(C)O,,,,val
+US05006544,CN1CCC(=O)c2ccccc21.Cc1c(C=O)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1[nH]cnc1Cc1cn(C)c2ccccc2c1=O,,CO,,[K+].[OH-],,val
+US20020022631A1,CCOC(=O)[C@H](Cc1cccc([N+](=O)[O-])c1)NC(C)=O>>CC(=O)N[C@H](CO)Cc1cccc([N+](=O)[O-])c1,,CCO,,[BH4-].[Na+],,val
+US20080085890A1,CC=O.O=C1NC(=O)c2ccc(I)cc2/C1=C/Nc1ccc(N2CCNCC2)nc1>>CCN1CCN(c2ccc(N/C=C3\C(=O)NC(=O)c4ccc(I)cc43)cn2)CC1,,CN1CCCC1=O,ClCCl,CC(=O)O,O=C([O-])O.[Na+],val
+US20130178459A1,CCC(CNC(=O)OC(C)(C)C)c1ccc(-c2c(OC)ccc3[nH]c(=O)c4sccc4c23)cc1.O=C1CCC(=O)N1Cl>>CCC(CNC(=O)OC(C)(C)C)c1ccc(-c2c(OC)cc(Cl)c3[nH]c(=O)c4sccc4c23)cc1,,CN(C)C=O,,,,val
+US20030092911A1,ClCCl.O=C(O)COCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1>>Cl.Cl.O=C(O)COCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1,,ClCCl,,,,val
+US20150225367A1,CC(C)(C)OC(=O)n1cc(-c2ccc(S(N)(=O)=O)nc2)c2ccc(F)cc21.Cl>>Cl.NS(=O)(=O)c1ccc(-c2c[nH]c3cc(F)ccc23)cn1,,CCOC(C)=O,,,,val
+US20100022518A1,COCC(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1CCN(c2cccc(C(F)(F)F)c2)C(C)C1=O>>COCC(CCO)N1CCN(c2cccc(C(F)(F)F)c2)C(C)C1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,val
+US04380638,CCN.CN(C)Cc1ccc(CSCCN)o1.COC1=NS(=O)N=C1OC>>CCNC1=NS(=O)N=C1NCCSCc1ccc(CN(C)C)o1,,CO,,,,val
+US04803279,NC1=NCCS1.O=C(CCl)c1ccc(F)cc1>>Fc1ccc(-c2cn3c(n2)SCC3)cc1,,O,,CCO,,val
+US20110224129A1,Brc1ccc(Br)s1.Cc1ccc(B(O)OC(=O)O)cc1>>COC(=O)c1ccc(-c2ccc(Br)s2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[K+].[K+],val
+US20120029190A1,N#Cc1cccc(C(=O)Cl)c1.c1ccc(-c2nc3c(o2)CNCC3)nc1>>N#Cc1cccc(C(=O)N2CCc3nc(-c4ccccn4)oc3C2)c1,,ClCCl,,,,val
+US04394156,Cc1cc(C)c([N+](=O)[O-])cc1N.N#CCC(=O)Cl>>Cc1cc(C)c([N+](=O)[O-])cc1NC(=O)CC#N,,C1CCOC1,,CCN(CC)CC,,val
+US20120010182A1,CC(C)(C)OC(=O)N1CC(NN)C1.COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(-c4ccccc4C(F)(F)F)cc3C(=O)/C=C/N(C)C)cc2F)c(OC)c1>>COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(-c4ccccc4C(F)(F)F)cc3-c3ccnn3C3CN(C(=O)OC(C)(C)C)C3)cc2F)c(OC)c1,,CC(=O)O,CCO,O=C([O-])O.[Na+],,val
+US04219559,CC(C)NC1CCN(CCc2ccccc2)CC1.O=[N+]([O-])c1ccccc1N=C=S>>CC(C)N(C(=S)Nc1ccccc1[N+](=O)[O-])C1CCN(CCc2ccccc2)CC1,,CCO,,C1CCOC1,,val
+US20040009526A1,O=C1CSC(=S)N1.O=Cc1ccc(-c2ccc(C(=O)O)cc2)o1>>O=C1NC(=S)SC1=Cc1ccc(-c2ccc(C(=O)O)cc2)o1,,CCO,,C1CCNCC1,,val
+US20100249119A1,Nc1cccc(O)c1.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(O)c1)c1cccc(C(F)(F)F)c1,,C1CCOC1,,O,O=C([O-])O.[Na+],val
+US20100202971A1,CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO[C@H]1O[C@H](CS(=O)(=O)O)[C@@H](OC(=O)CCNC(=O)OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO[C@H]1O[C@H](CS(=O)(=O)O)[C@@H](OC(=O)CCN)[C@H](O)[C@H]1O,[Pd],CC(=O)O,CO,,,val
+US20100130558A1,CC(C)C(C(=O)N[C@H]1CC[C@@H]2CNC[C@H]12)c1ccccc1.O=C(Cl)c1ccccc1>>CC(C)C(C(=O)N[C@H]1CC[C@@H]2CN(C(=O)c3ccccc3)C[C@H]12)c1ccccc1,,ClCCl,,CCN(CC)CC,,val
+US20080255115A1,C=C[Sn](CCCC)(CCCC)CCCC.Clc1ccnc2ccc(Br)cc12>>C=Cc1ccc2nccc(Cl)c2c1,,C1COCCO1,,,,val
+US20070135477A1,COC(=O)c1cccc([N+](=O)[O-])c1NC(C)=O>>COC(=O)c1cccc([N+](=O)[O-])c1N,,CO,,Cl,C[O-].[Na+],val
+US20060128685A1,COc1ccc(-n2nc(C(=O)O)cc2-c2ccccc2)cn1>>COc1ccc(-n2nc(CO)cc2-c2ccccc2)cn1,,C1CCOC1,,CCOC(C)=O,O,val
+US04988689,BrCCc1ccccc1.Fc1ccc(Cn2c(NC3CCNC3)nc3ccccc32)cc1>>Fc1ccc(Cn2c(NC3CCN(CCc4ccccc4)C3)nc3ccccc32)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],val
+US20120245136A1,CC(C)OCC1CC2(CCN(C(=O)OC(C)(C)C)CC2)Oc2ccccc21.Cl>>CC(C)OCC1CC2(CCNCC2)Oc2ccccc21.Cl,,C1COCCO1,,ClCCl,,val
+US20030008882A1,COc1ccc(-c2ccc(-c3ccc(CCC#N)cc3CC(C)C)cc2Cc2ccccc2)cc1CC(C)C>>CC(C)Cc1cc(-c2ccc(-c3ccc(CCC#N)cc3CC(C)C)cc2Cc2ccccc2)ccc1O,,ClCCl,,BrB(Br)Br,O,val
+US20110130419A1,CCO.Cc1cccc2c(=O)[nH]c(CCN3CCC[C@@H]3CO)cc12.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>Cc1cccc2c(=O)[nH]c(CCN3CCC[C@@H]3CO)cc12.O.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CCO,,,,val
+US20080015199A1,BrCCOC1CCCCO1.COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(O)c(OC)c(OC)c1>>COC(=O)N=C(SC)C(Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c(OC)c(OCCOC2CCCCO2)c1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],val
+US20110183989A1,Nc1ccnn1-c1ccccc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccnn1-c1ccccc1)Oc1ccccc1,,ClCCCl,ClCCl,,,val
+US20120214762A1,C#C[Mg]Br.CC(=O)c1ncn(C)n1>>C#CC(C)(O)c1ncn(C)n1,,C1CCOC1,,,,val
+US20110039843A1,FC(F)(F)c1c[nH]cn1.Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1>>FC(F)(F)c1ccc2oc(-c3ccncc3-n3cnc(C(F)(F)F)c3)nc2c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],val
+US20070203137A1,N#Cc1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>N#Cc1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CCO,O,C,,val
+US20070004675A1,CNC.O=Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1>>CN(C)Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,val
+US05250528,O=C(Cl)c1cccs1.O=NN1CCNCC1>>O=NN1CCN(C(=O)c2cccs2)CC1,,C1COCCO1,O,CCOC(C)=O,c1ccncc1,val
+US20150018363A1,CNc1cc(-n2ccc(OCc3ccc(Cl)cc3)cc2=O)ccc1N.O=C(O)C1CCC1>>Cn1c(C2CCC2)nc2ccc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20100280030A1,CC(=O)c1ccc2[nH]c(=O)oc2c1>>CC(O)c1ccc2[nH]c(=O)oc2c1,[Pd],CO,,,,val
+US20110319406A1,CCOC(CBr)OCC.Fc1ccccc1S>>CCOC(CSc1ccccc1F)OCC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20090143353A1,CCOC(=O)[C@@H]1C[C@H]1c1nc2c(C#N)c(C)c(-c3ccccc3)c(F)c2o1.CN(C)[C@H]1CCNC1>>CCOC(=O)[C@@H]1C[C@H]1c1nc2c(C#N)c(C)c(-c3ccccc3)c(N3CC[C@H](N(C)C)C3)c2o1,,CS(C)=O,,CCN(CC)CC,,val
+US05077288,Cl.O=C(c1ccc(F)cc1)C1CCN(CCCCl)CC1.O=C1CN(Cc2ccccn2)CC(=O)N1>>Cl.O=C(c1ccc(F)cc1)C1CCN(CCCN2C(=O)CN(Cc3ccccn3)CC2=O)CC1,,CCO,CN(C)C=O,[H-].[Na+],,val
+US20150274777A1,CC(C)(C)OC(=O)N[C@@H](CCc1ccccc1)C(=O)O.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCc1ccccc1)C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,val
+US07067540B2,CC(=O)OCC(=O)Cl.Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1cc(NC(=O)OC(C)(C)C)ccc1F>>CC(=O)OCC(=O)Nc1ccc(F)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1,,C1CCOC1,,CCN(CC)CC,[Cl-].[NH4+],val
+US20080293718A1,CN1C(=O)C(c2ccccc2)(c2cccc(O)c2)NC1=S.CS(=O)(=O)Cl>>CN1C(=O)C(c2ccccc2)(c2cccc(OS(C)(=O)=O)c2)NC1=S,,ClCCl,,CCN(CC)CC,,val
+US20120082702A1,C1CCNCC1.CS(=O)(=O)c1ccc(Nc2nc(Cl)ccc2C(N)=O)cc1>>CS(=O)(=O)c1ccc(Nc2nc(N3CCCCC3)ccc2C(N)=O)cc1,,CCOC(C)=O,,,,val
+US20100197926A1,CCN(CC)C(=O)Cl.COc1cccc(O)c1C>>CCN(CC)C(=O)Oc1cccc(OC)c1C,,CC#N,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],val
+US20110275678A1,NC1CCCC1.O=C(OCc1ccncc1)Oc1ccc([N+](=O)[O-])cc1>>O=C(NC1CCCC1)OCc1ccncc1,CN(C)c1ccncc1,CN(C)C=O,,CCN(C(C)C)C(C)C,,val
+US03993679,Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1>>Cc1cc(N)c(Cl)c(N)c1,,CCO,,Cl,[Na+].[OH-],val
+US20070244095A1,O=C1Nc2c(ccc3c2CCC3)C1=O.OO>>Nc1c(C(=O)O)ccc2c1CCC2,,O,,Cl,[Na+].[OH-],val
+US04929613,CC(=O)N1CC=C(c2cc(F)c(C(=O)O)cc2F)CC1>>CC(=O)N1CCC(c2cc(F)c(C(=O)O)cc2F)CC1,[Pd],CC(=O)O,,,,val
+US06894169B1,Cc1ccncc1.OCCCCCCBr>>Cc1cc[n+](CCCCCCO)cc1.[Br-],,CCO,,,,val
+US20140088066A1,BrP(Br)Br.CN(C)C=O.O=C1CCCCC1>>O=CC1=C(Br)CCCC1,,ClC(Cl)Cl,O,O=C([O-])O.[Na+],,val
+US04810800,NCCCc1cccs1>>NCCCc1cccs1,,CN(C)C=O,,Cl,,val
+US20080085910A1,COC(=O)C(C/C=C/c1ccc(C2(OC)CCOCC2)cc1)NC(=O)c1c(Cl)cccc1Cl>>COC1(c2ccc(/C=C/CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)CCOCC1,,C1CCOC1,,[Na+].[OH-],,val
+US20050187387A1,CC(=O)c1cc(F)c(Cl)cc1O.CCOC(=O)C(=O)OCC>>O=C(O)c1cc(=O)c2cc(F)c(Cl)cc2o1,,CCOCC,,C,C[O-].[Na+],val
+US20060100194A1,CCOC(=O)C1CC(=O)Nc2ccc(I)cc2C1=O>>O=C1CCC(=O)c2cc(I)ccc2N1,,CS(C)=O,,O,[Cl-].[Na+],val
+US20140256740A1,Cc1ccc(C(NC(=O)Cc2ccc(OCC(=O)c3c(C)noc3C)cc2)c2ccccc2)c(C)c1>>Cc1ccc(C(NC(=O)Cc2ccc(OCC(O)c3c(C)noc3C)cc2)c2ccccc2)c(C)c1,,CO,,O,[BH4-].[Na+],val
+US20100069352A1,CC(=O)Cl.COc1cc(-n2ccc3nc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OC1CNC1>>COc1cc(-n2ccc3nc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OC1CN(C(C)=O)C1,,ClCCl,,CCN(CC)CC,Cl,val
+US20090286778A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Br)cc(C(=O)O)c1>>CC(C)(C)OC(=O)Nc1cc(Br)cc(C(=O)O)c1,,C1COCCO1,O,CCN(CC)CC,,val
+US05571816,CC(C)N(C(=O)c1cnc(N2CC(C)(C)NC2=O)nc1N)c1cccc(C(F)(F)F)c1.Cl>>CC(C)N(C(=O)c1cnc(N2CC(C)(C)NC2=O)nc1N)c1cccc(C(F)(F)F)c1.Cl,,CC(C)=O,CCOCC,,,val
+US20100204196A1,C=CC(=O)N1CCCc2cc(OC)c([N+](=O)[O-])cc21.CNC>>COc1cc2c(cc1[N+](=O)[O-])N(C(=O)CCN(C)C)CCC2,,CO,,,,val
+US20050032786A1,C[S-].N#Cc1cc(Cl)ccn1>>CSc1ccnc(C#N)c1,,C1CCOC1,,CCOC(C)=O,O,val
+US20150299188A1,CC(=O)O.COc1cc(N)c(C=O)c(C2CC2)n1.Nc1cc2c(cc1Cl)CCC(c1ncccc1F)O2>>COc1cc2c(c(C3CC3)n1)CN(c1cc3c(cc1Cl)CCC(c1ncccc1F)O3)C(=O)N2,,CC(=O)O,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],val
+US20050277652A1,CNCCCN1CCN(C)CC1.Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1.O=C(Cl)Oc1ccccc1>>CN1CCN(CCCN(C)C(=O)Nc2cc(Oc3ccc([N+](=O)[O-])cc3F)ccn2)CC1,,CN(C)C=O,,C1CCOC1,CCN(CC)CC,val
+US20070149514A1,CC(C)c1c[nH]c2ccc(Br)cc12.CCOC(=O)COc1ccc(S(=O)(=O)Cl)cc1C>>CCOC(=O)COc1ccc(S(=O)(=O)n2cc(C(C)C)c3cc(Br)ccc32)cc1C,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US20100298566A1,Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2O.O=P(O)(O)O>>Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2O.O=P([O-])([O-])[O-],,CO,,,,val
+US20070208054A1,O=C(O)CBr.OCc1ccc(Br)cc1>>O=C(O)COCc1ccc(Br)cc1,,C1CCOC1,O,CO,[H-].[Na+],val
+US20090062251A1,COC(=O)c1ccc(N)c(Cl)c1.O=C1CCC1>>COC(=O)c1ccc(NC2CCC2)c(Cl)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],val
+US20160221972A1,COC(=O)c1ccc2c(c1)O[C@H](c1ccccc1)CN(C(=O)Nc1ccc(OC)cc1)C2.NO>>COc1ccc(NC(=O)N2Cc3ccc(C(=O)NO)cc3O[C@H](c3ccccc3)C2)cc1,,C1CCOC1,CO,[Na+].[OH-],,val
+US20060287342A1,Clc1ccc(-c2cnc(Cl)nc2-c2ccncc2)cc1.NN>>NNc1ncc(-c2ccc(Cl)cc2)c(-c2ccncc2)n1,,c1ccncc1,,O,,val
+US04904815,C=CC(C)(C)Br.CCOC(=O)C(C)P(=O)(OCC)OCC>>CCOC(=O)C(CC=C(C)C)P(=O)(OCC)OCC,,CCO,,[Na],,val
+US20110237590A1,N#CCCCBr.NC(=O)Cc1cnc(Nc2ccc(N)cc2)cc1NCc1ccccc1>>N#CCCCNc1ccc(Nc2cc(NCc3ccccc3)c(CC(N)=O)cn2)cc1,,O,,CN(C)C=O,O=C([O-])O.[Na+],val
+US20160108056A1,CC(C)(c1cccc(CO)c1)c1cc(Br)cc([N+](=O)[O-])c1.CS(=O)(=O)Cl>>CC(C)(c1cccc(COS(C)(=O)=O)c1)c1cc(Br)cc([N+](=O)[O-])c1,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US20100331326A1,C[Si](C)(C)CCOCn1ccc2cc(Br)cnc21.O=C1NCCN1c1ccc2ncsc2c1>>C[Si](C)(C)CCOCn1ccc2cc(N3CCN(c4ccc5ncsc5c4)C3=O)cnc21,I[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],val
+US20100081680A1,NS(=O)(=O)c1ccc(C(F)(F)F)cc1.O=Cc1ccccc1I>>O=S(=O)(/N=C/c1ccccc1I)c1ccc(C(F)(F)F)cc1,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,ClCCl,CCN(CC)CC,,val
+US05344845,CCCCCNCCCCC.COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCCCl>>CCCCCN(CCCCC)CCOc1ccc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)cc1OC,,CC(=O)CC(C)C,,,,val
+US06194410B1,CN1CCNCC1.CSc1nn2c(O)cc(CCl)nc2c1S(=O)(=O)c1ccccc1>>CSc1nn2c(O)cc(CN3CCN(C)CC3)nc2c1S(=O)(=O)c1ccccc1,,CN(C)C=O,,,,val
+US20080200507A1,BrP(Br)Br.COc1cccc(C2CCc3cc(OC)ccc3C2=O)c1>>COc1cccc(C2=C(Br)c3ccc(OC)cc3CC2)c1,,Cc1ccccc1,,,,val
+US20100184741A1,CC1(C)CCN(S(=O)(=O)c2cc(Br)c(Cl)cc2F)c2ccccc21.COC(=O)CC(=O)OC>>COC(=O)C(C(=O)OC)c1cc(Cl)c(Br)cc1S(=O)(=O)N1CCC(C)(C)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,val
+US04372953,Cn1nnnc1S.O=C(CCCCl)Cc1ccccc1>>Cn1nnnc1SCCCC(=O)Cc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US04492792,CCCCOC=C(C#N)C(OCCCC)OCCCC.CCCC[O-]>>CCCCOC(OCCCC)C(C#N)C(OCCCC)OCCCC,,CCCCO,,O=S(=O)(O)O,,val
+US20110046378A1,CC(C)(C)OC(=O)Nc1ccc2c(c1)[nH]c1cc(OCc3ccccc3)ccc12>>CC(C)(C)OC(=O)Nc1ccc2c(c1)[nH]c1cc(O)ccc12,[Pd],CO,,,,val
+US05891603,Cc1ccc2c(c1)C(=O)OC2=O.NO>>Cc1ccc2c(c1)C(=O)N(O)C2=O,,O,,Cl,[Na+].[OH-],val
+US20130137680A1,CCOC(=O)c1ccc2cc(C(=O)OCC)n(CC(C)(C)CN)c2n1>>CC1(C)CNC(=O)c2cc3ccc(C(=O)O)nc3n2C1,,CCO,,O=C([O-])[O-].[K+].[K+],,val
+US20130158276A1,O=C1CCc2ccccc21>>O[C@@H]1CCc2ccccc21,,CO,,[H][H],,val
+US20140357642A1,Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(C(=O)OC(C)(C)C)CC(O)C3O)cc1.S=C(n1ccnc1)n1ccnc1>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(C(=O)OC(C)(C)C)CC2OC(=S)OC32)cc1,,C1CCOC1,,,,val
+US06034246,Nc1ccc(C(=O)O)cc1.Nc1ccccc1S>>Nc1ccc(-c2nc3ccccc3s2)cc1,,O=C([O-])O,[Na+],,,val
+US20120264749A1,CC(C)(C)OC(=O)N1CCC2(CC1)CO2.COc1ccc(CNC(CO)c2ccccc2)cc1>>COc1ccc(CN(CC2(O)CCN(C(=O)OC(C)(C)C)CC2)C(CO)c2ccccc2)cc1,,CCO,,,,val
+US20120328540A1,CC(C)=CCC/C(C)=C/CC/C(C)=C/CSC[C@H](N)C(=O)O.O=C1C=CC(=O)O1>>CC(C)=CCC/C(C)=C/CC/C(C)=C/CSC[C@H](NC(=O)/C=C/C(=O)O)C(=O)O,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],val
+US20030229079A1,BrC(Br)(Br)Br.COC(=O)c1cc(CO)ccn1>>COC(=O)c1cc(CBr)ccn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,val
+US04968711,CC(=O)N[C@@H](CS)C(=O)O.CO>>CC(=O)N(C)[C@@H](CS)C(=O)O,Cl,,,,,val
+US20080207732A1,COC(=O)c1ccc(OCCO)cc1>>O=C(O)c1ccc(OCCO)cc1,,CO,,[Na+].[OH-],,val
+US20050171110A1,O=c1c(Cl)c(Cl)c(OCc2ccccc2)nn1Cc1ccccc1.OB(O)c1ccc(Cl)cc1>>O=c1c(-c2ccc(Cl)cc2)c(Cl)c(OCc2ccccc2)nn1Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,val
+US20090036422A1,CC(=O)O[C@H](C(=O)N(CCc1ccc(F)cc1)c1ccc(C)c(C)c1)c1ccccc1>>Cc1ccc(N(CCc2ccc(F)cc2)C(=O)[C@@H](O)c2ccccc2)cc1C,,C1CCOC1,O,[Li+].[OH-],,val
+US20090291937A1,CC(C)(C)OC(=O)NCCCc1cc(Br)cc(C2(C#N)CC2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)OC(=O)NCCCc1cc(B2OC(C)(C)C(C)(C)O2)cc(C2(C#N)CC2)c1,,C1COCCO1,CCOC(C)=O,ClCCl,CC(=O)[O-].[K+],val
+US20020103253A1,COC(=O)c1sc(C(C)(C)C)cc1NC(=O)Nc1ccccc1[N+](=O)[O-]>>COC(=O)c1sc(C(C)(C)C)cc1NC(=O)Nc1ccccc1N,[Pd],CO,,,,val
+US20100010035A1,CCc1cc2c(c(-c3ccccc3)cc(=O)n2C(S)c2ccc(-c3ccsc3S(=O)(=O)N(COCCOC)c3noc(C)c3C)cc2)c(CC)n1>>CCc1cc2c(c(-c3ccccc3)cc(=O)n2C(S)c2ccc(-c3ccsc3S(=O)(=O)Nc3noc(C)c3C)cc2)c(CC)n1,,CCO,O,Cl,O=C([O-])O.[Na+],val
+US20150119385A1,COC(OC)c1nc2c(cc1-n1ccnc1)CCCN2.O=C(Oc1ccccc1)Oc1ccccc1>>COC(OC)c1nc2c(cc1-n1ccnc1)CCCN2C(=O)Oc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,val
+US20040162303A1,CC(=O)OCBr.COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N>>COC(=O)CN1CCC(Nc2ncc(C(=O)c3cc(F)ccc3OC)c(N)n2)CC1,,CN(C)C=O,,O,,val
+US04820734,O=C1CCCC[C@H]1[C@@H](C[N+](=O)[O-])c1ccc(OCc2ccccc2)cc1>>NC[C@@H](c1ccc(OCc2ccccc2)cc1)[C@@H]1CCCC[C@@H]1O,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],val
+US05389486,BrC(c1ccccc1)c1ccccc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Br-].c1ccc(C(c2ccccc2)[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,CC#N,CCOCC,,,val
+US20040009995A1,COC(=O)CCCCC(=O)Nc1cccc(C)c1-c1cccc(S(=O)(=O)c2cc(C(=N)NC(=O)OC(C)(C)C)sc2SC)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)CCCCC(=O)O)c1,,CCOC(C)=O,,CO,[Li+].[OH-],val
+US20120058984A1,CSc1nccc(N)n1.Clc1nc2ccc(Br)cc2s1>>CSc1nccc(Nc2nc3ccc(Br)cc3s2)n1,,C1CCOC1,,O,[H-].[Na+],val
+US20110065699A1,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.COc1cccc(C(=O)CBr)c1>>COc1cccc(-c2cn3cc(B4OC(C)(C)C(C)(C)O4)ccc3n2)c1,,CCCO,,O=C([O-])O.[Na+],,val
+US20040058945A1,CC(=O)Nc1ccc2nc(-c3ccc(C4CCCCC4)cc3)cc(N)c2c1>>Nc1ccc2nc(-c3ccc(C4CCCCC4)cc3)cc(N)c2c1,,Cl,,[Na+].[OH-],,val
+US06448270B1,C#CCCS(C)(=O)=O.c1ccc(CC2CCNCC2)cc1>>C#CCCN1CCC(Cc2ccccc2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20100056532A1,CCOC(=O)c1c(C2CCCCC2)csc1NC(=O)Nc1ccc(F)c(F)c1>>O=C(Nc1ccc(F)c(F)c1)Nc1scc(C2CCCCC2)c1C(=O)O,,CCO,,[Na+].[OH-],,val
+US04086423,COC(NC(=O)Cc1cccs1)C(=O)[O-]>>COC(NC(=O)Cc1cccs1)C(=O)O,,CO,,[K+].[OH-],,val
+US20120088791A1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.CCOC(=O)N1CCC(=O)CC1.Cc1ccccc1C(=O)Cl>>CCOC(=O)N1CCC(N2CCC[C@@H](NC(=O)c3ccccc3C)C2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US20120122838A1,Clc1cc(OCc2ccccc2)c2nccn2n1>>Cl.Oc1ccnn2ccnc12,[Pd],CO,,,,val
+US20110190266A1,Cn1ncnc1CC1(O)OC(=O)C2=C1C(N)CCC2.O=C(O)[C@@H]1CCCN1.O=Cc1ccc(F)cc1>>Cn1ncnc1C1C(=O)C2=C(C(=O)O)CCCC2NC1c1ccc(F)cc1,,CO,ClCCl,,,val
+US20120309773A1,COc1cccc(N)c1.O=C(O)c1cc(Nc2nc(Cl)nc3ccoc23)n[nH]1>>COc1cccc(NC(=O)c2cc(Nc3nc(Cl)nc4ccoc34)n[nH]2)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US06372764B1,CO.O=C(O)C1CN(C(=O)c2cccc3ccccc23)CC1CN1CCC(c2ccc(F)cc2)CC1>>COC(=O)C1CN(C(=O)c2cccc3ccccc23)CC1CN1CCC(c2ccc(F)cc2)CC1,,C1CCOC1,CO,C[Si](C)(C)C=[N+]=[N-],,val
+US20150274733A1,CC1c2cnc(NC3CCOCC3)nc2CN1C(=O)OC(C)(C)C>>CC1NCc2nc(NC3CCOCC3)ncc21,,C1COCCO1,CO,Cl,,val
+US20090137595A1,Cc1nc2ccc(O)cc2s1.O=C(Nc1cn2nc(I)ccc2n1)C1CC1>>Cc1nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)cc2s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US05145970,Cc1cc(S)cc(C(C)(C)C)c1N.O=C1C=CC(=O)N1c1ccccc1>>Cc1cc(SC2CC(=O)N(c3ccccc3)C2=O)cc(C(C)(C)C)c1N,,Cc1ccccc1,,CCN(CC)CC,,val
+US20070054884A1,BrBr.Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl>>Oc1cc(Cl)c(Br)cc1Oc1ccc(Cl)cc1Cl,,CC(=O)O,O,,,val
+US20090270467A1,C#CCN(CC#C)S(=O)(=O)c1ccc(C)cc1.O=C(O)Cc1cccs1>>Cc1ccc(S(=O)(=O)N2Cc3cscc3C2)cc1,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,val
+US20110218193A1,CCCBr.COc1ccc(Cn2c(=O)c3c(c4cc(OC)ccc42)NCCC3)cc1>>CCCN1CCCc2c1c1cc(OC)ccc1n(Cc1ccc(OC)cc1)c2=O,,CN(C)C=O,,O,[H-].[Na+],val
+US20160143870A1,CC(C)CN(CC(C)C)c1ccc(Br)cc1N.CC1(C)COB(B2OCC(C)(C)CO2)OC1>>CC(C)CN(CC(C)C)c1ccc(B2OCC(C)(C)CO2)cc1N,,CS(C)=O,,CC(=O)[O-].[K+],,val
+US20060063805A1,N[C@@H](CO)c1ccccc1.O=C1CSC(=S)N1>>O=C1CSC(N[C@@H](CO)c2ccccc2)=N1,,CC#N,,CCN(C(C)C)C(C)C,,val
+US04526978,CN=[N+]=[N-].Cc1ccc(S(=O)(=O)C#N)cc1>>Cc1ccc(S(=O)(=O)c2nnnn2C)cc1,,c1ccccc1,,,,val
+US20060229286A1,CC(=O)N1CCc2cc(C(=O)O)ccc21>>CC(=O)n1ccc2cc(C(=O)O)ccc21,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,val
+US04629493,COC(=O)C(C)Oc1ccc(O)cc1.Clc1ccc2nc(Cl)cnc2c1>>COC(=O)C(C)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20090054405A1,CN(C)c1cc(-c2ccc3nc(N)sc3c2)cnc1Cl.NCCN1CCOCC1.O=C(n1ccnc1)n1ccnc1>>CN(C)c1cc(-c2ccc3nc(NC(=O)NCCN4CCOCC4)sc3c2)cnc1Cl,,CN(C)C=O,ClCCl,,,val
+US04978753,CCC(=O)OC(=O)CC.O=c1ccn2c(n1)C(O)N=C(c1ccccc1Cl)c1cc(Cl)ccc1-2>>CCC(=O)O.O=c1ccn2c(n1)C(O)N=C(c1ccccc1Cl)c1cc(Cl)ccc1-2,,c1ccncc1,,,,val
+US06207365B1,CC(=O)O.CCOC(=O)C(C)=Cc1ccc(OC)cc1OC>>CCOC(=O)C(C)=Cc1c(OC)cc(OC)cc1OC(C)=O,,c1ccncc1,,,,val
+US20140107194A1,CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.CCOC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2O)cc1>>CCOC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2OC(=O)[C@@H](N)CC(C)C)cc1,CN(C)c1ccncc1,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,val
+US20100087417A1,CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1OCCOS(C)(=O)=O.CN>>CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1OCCNC,,CO,,,,val
+US20150191461A1,C=Cc1nc(Cl)ncc1F.O.O=[Os](=O)(=O)=O>>OC(O)c1nc(Cl)ncc1F,O=[Os](=O)(=O)=O,,,C1CCOC1,,val
+US20090221597A1,Cc1cc(O)nc(N)n1.O=C(Cl)C1(c2ccc3c(c2)OCO3)CC1>>Cc1cc(O)nc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)n1,,c1ccncc1,,,,val
+US20140045936A1,CN.COC(=O)C1(c2ccc(-c3ccccc3)cc2)CC1C=O.Cl>>CNCC1CC1(C(=O)OC)c1ccc(-c2ccccc2)cc1.Cl,,CCOCC,CO,[BH4-].[Na+],,val
+US20100297035A1,CCOC(=O)c1[nH]c(-c2cccc3ccccc23)nc1C>>Cc1nc(-c2cccc3ccccc23)[nH]c1CO,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,val
+US06384065B1,CC(C)CC=C1CCC2(CC1)SC(CC(=O)OC(C)(C)C)C(=O)N2CCC(=O)O.CCI>>CCOC(=O)CCN1C(=O)C(CC(=O)OC(C)(C)C)SC12CCC(=CCC(C)C)CC2,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],val
+US20060142359A1,Nc1onc2c1CCC2.O=Cc1ccccc1>>C(=Nc1onc2c1CCC2)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,val
+US04299821,NC(=O)[C@H]1CCCCN1C(=O)OCc1ccccc1>>NC(=O)[C@H]1CCCCN1,[Pd],CO,,,,val
+US20130338134A1,C1COCCN1.CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc3c(cc(C=O)n3S(=O)(=O)c3ccccc3)c21>>CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc3c(cc(CN4CCOCC4)n3S(=O)(=O)c3ccccc3)c21,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],val
+US20090270351A1,COP(=O)(OC)C(F)c1ccc(C(=O)OCc2ccccc2)cc1>>COP(=O)(OC)C(F)c1ccc(C(=O)O)cc1,[Pd],CO,,,,val
+US03957922,CC1CO1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.c1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1>>CC1CO1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.c1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1,[Fe],CCN(CC)CC,,[Al],,val
+US20070032501A1,BrBr.Nc1ccc(-c2ccc(F)cc2)cn1>>Nc1ncc(-c2ccc(F)cc2)cc1Br,,CC(=O)O,ClCCl,CC(=O)[O-].[Na+],,val
+US20120101127A1,C=C(C)C.Nc1ccc(Cl)cc1.O=Cc1cccc(Br)c1>>CC1(C)CC(c2cccc(Br)c2)Nc2ccc(Cl)cc21,,CC#N,CCOC(C)=O,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,val
+US20090123372A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O[C@@H]1CO[C@@H](c2ccccc2)OC1>>O=S(=O)(O[C@@H]1CO[C@@H](c2ccccc2)OC1)C(F)(F)F,,ClCCl,,,,val
+US20150274696A1,O=C(Nc1ccn2nccc2c1)C(F)(F)F.O=C1CCC(=O)N1Cl>>O=C(Nc1ccn2ncc(Cl)c2c1)C(F)(F)F,,CC#N,,,,val
+US05719152,CCOC(=O)C(CCc1cc(CNC(=O)OC(C)(C)C)ccc1[N+](=O)[O-])C(=O)OCC>>CCOC(=O)C(CCc1cc(CNC(=O)OC(C)(C)C)ccc1N)C(=O)OCC,[Pd],CCOC(C)=O,,[H][H],,val
+US04863904,CCOC(=O)C(CN)Cc1ccccc1.O=C(O)Cc1cccc2ccccc12>>CCOC(=O)C(CNC(=O)Cc1cccc2ccccc12)Cc1ccccc1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,val
+US20060094767A1,COCOC[C@](C)(O)Cn1cc([N+](=O)[O-])nc1Cl>>COCOC[C@@]1(C)Cn2cc([N+](=O)[O-])nc2O1,,CN(C)C=O,,[H-].[Na+],,val
+US20070073056A1,CC1C(C(=O)O)=NN(c2ccc(Cl)cc2Cl)C1c1ccc(Cl)cc1.CI>>COC(=O)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccc(Cl)cc2)C1C,,CN(C)C=O,,O,,val
+US20090035215A1,CC(C)C[Si](CCCCC(=O)ON1C(=O)CCC1=O)(CC(C)C)OCCCCc1ccccc1.Nc1ccccc1>>CC(C)C[Si](CCCCC(=O)Nc1ccccc1)(CC(C)C)OCCCCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,val
+US05037714,N#CC(C#N)=Cc1ccc(O)cc1.O=S(=O)(Cl)c1cc(Cl)c(Cl)cc1Cl>>N#CC(C#N)=Cc1ccc(OS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)cc1,,c1ccncc1,,,,val
+US20130052151A1,C=CCCCCCCCCCC(=O)CC(C)CCC=C(C)C>>CC1CCC=CCCCCCCCCCC(=O)C1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,,,val
+US20100087431A1,CC(C)(C)[S@@](N)=O.ClCCCl.O=Cc1ccc(F)cc1Br>>C/C(=N\[S@@](=O)C(C)(C)C)c1ccc(F)cc1Br,,O,,,,val
+US20080153817A1,CCCC1(CC(=O)[O-])CCCCC1=O.CCC[C@@H](c1ccc(C(F)(F)F)cc1)N(N)c1ccc(C(C)C)cc1.CCO>>CCCC(c1ccc(C(F)(F)F)cc1)n1c2c(c3cc(C(C)C)ccc31)CCCC2(CCC)CC(=O)OC,Cl,,,,,val
+US20140073620A1,Cc1nn(C)cc1N.NC(=O)C1(c2ccccc2CCc2nc(Cl)ncc2Cl)CC1>>Cc1nn(C)cc1Nc1ncc(Cl)c(CCc2ccccc2C2(C(N)=O)CC2)n1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,O,val
+US20140134235A1,Fc1ccc(CNCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(N(CC2CC2)CC2CC2)n1.N#CBr>>N#CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1ccc(F)nc1N(CC1CC1)CC1CC1,,CO,,O=C([O-])O.[Na+],,val
+US20150087646A1,N#Cc1ccc(I)c(F)c1.OO>>NC(=O)c1ccc(I)c(F)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US20030158198A1,Cc1cc2c(N)cccc2c(C)n1.O=C=NCc1ccc(C(F)(F)F)c(F)c1>>Cc1cc2c(NC(=O)NCc3ccc(C(F)(F)F)c(F)c3)cccc2c(C)n1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,val
+US05843942,BrC(Br)(Br)Br.CC(O)c1cc(Br)ccc1OCc1ccccc1>>CC(Br)c1cc(Br)ccc1OCc1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,val
+US06140342,CCOC(=O)N(Cc1ccccc1)[C@@H]1C[C@H](C)Nc2cc(OC)c(OC)cc21.O=C(Cl)Cl>>CCOC(=O)N(Cc1ccccc1)[C@@H]1C[C@H](C)N(C(=O)Cl)c2cc(OC)c(OC)cc21,,Cc1ccccc1,,,,val
+US20050288367A1,CNC(=O)COc1ccc(OCc2ccccc2)cc1>>CNC(=O)COc1ccc(O)cc1,[Pd],C1CCOC1,,,,val
+US20100298558A1,C[N+](=O)[O-].O=C(C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(CN2C(=O)c3ccccc3C2=O)c(Br)c1>>O=C(CC(C[N+](=O)[O-])(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(CN2C(=O)c3ccccc3C2=O)c(Br)c1,,CC#N,,C1CCC2=NCCCN2CC1,O,val
+US20030134853A1,N#Cc1ccc(NC2CCCCC2)c([N+](=O)[O-])c1>>N#Cc1ccc(NC2CCCCC2)c(N)c1,[Pd],CCOC(C)=O,CO,,,val
+US04808597,Cc1ccc2c(c1)C(C)(C)CCO2.O=C1CCC(=O)N1Br>>CC1(C)CCOc2ccc(CBr)cc21,,ClC(Cl)(Cl)Cl,,,,val
+US20070032515A1,COc1cc(-c2c(C)n[nH]c2N)ccc1OCC1CCN(C(=O)OC(C)(C)C)CC1.O=C(O)C(F)(F)F.O=Cc1ccc(O)cc1>>COc1cc2c(cc1OCC1CCNCC1)c(-c1ccc(O)cc1)nc1[nH]nc(C)c12.O=C(O)C(F)(F)F,,CN(C)C=O,,,,val
+US20160039788A1,O=C1CCc2cc(/C=C/CCBr)cnc2N1>>O=C1CCc2cc(CCCCBr)cnc2N1,[Rh],CCO,,,,val
+US20140080822A1,COC(=O)c1c(N)ccc2c1CCn1nccc1-2.O=S(=O)(Cl)c1ccc(F)cc1Br>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1CCn1nccc1-2,,ClCCl,c1ccncc1,,,val
+US20090221555A1,CNC(=O)[C@@H]1CCC[C@@H]1Nc1nc(Cl)ncc1Cl.COc1cc2c(cc1N)CCN(CC(=O)N(C)C)CC2>>CNC(=O)[C@@H]1CCC[C@@H]1Nc1nc(Nc2cc3c(cc2OC)CCN(CC(=O)N(C)C)CC3)ncc1Cl,,CC(C)O,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,val
+US20140194431A1,CCOC(C)=O.N#CC1(c2cccc3ccccc23)CCCC1>>O=CC1(c2cccc3ccccc23)CCCC1,,CCCCCC,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,val
+US05095014,CN.O=C(Cl)N1CC(Oc2cc(C(F)(F)F)ccc2F)C1>>CNC(=O)N1CC(Oc2cc(C(F)(F)F)ccc2F)C1,,C1CCOC1,O,,,val
+US20160130254A1,CCN(c1ccc(C#N)c(C(F)(F)F)c1)C1CC=C(c2c[nH]cn2)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCN(c1ccc(C#N)c(C(F)(F)F)c1)C1CC=C(c2cn(S(=O)(=O)c3ccc(C)cc3)cn2)C1,,ClCCl,O,,,val
+US20040147608A1,CCOC(=O)C1(C#N)CC1CC(C)C>>CCOC(=O)C1(CN)CC1CC(C)C,[Ni],CCO,,CCN(CC)CC,,val
+US20120101110A1,COCc1cccc(C(=O)O)c1.O=S(Cl)Cl>>COCc1cccc(C(=O)Cl)c1,CN(C)C=O,ClCCl,,,,val
+US20140243353A1,COc1cc(C#Cc2ccccc2C)cnc1OC>>Cc1ccccc1CCc1c[nH]c(=O)c(O)c1,[Pd],CC(=O)O,CO,Br,O,val
+US20060235032A1,COC(=O)CC1c2cccc(F)c2N=C(c2ccc(Br)cc2)N1c1cc(C(F)(F)F)ccc1OC.OB(O)c1cccc(F)c1>>COC(=O)CC1c2cccc(F)c2N=C(c2ccc(-c3cccc(F)c3)cc2)N1c1cc(C(F)(F)F)ccc1OC,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,val
+US20030092720A1,CC(C)c1csc(COc2ccnc(NC(=O)OC(C)(C)C)c2)n1>>CC(C)c1csc(COc2ccnc(N)c2)n1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2ccc(C)cc2OC)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F>>COc1cc(C)ccc1[C@H]1O[C@H](CC(=O)O)c2nnc(C(F)(F)F)n2-c2ccc(Cl)cc21,,C1COCCO1,,Cl,O,val
+US20120208827A1,Nc1cc(C(F)(F)F)ccc1NC[C@@H]1CCN(C(=O)C2CC2)C1.O=Cc1ccc(Br)cc1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)nc3cc(C(F)(F)F)ccc32)C1,[Pd],CCCCO,,,,val
+US20070032478A1,O=[N+]([O-])c1ccc(F)cc1.OCCCN1CCC(F)C1>>O=[N+]([O-])c1ccc(OCCCN2CCC(F)C2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,val
+US20090181942A1,CC(C)OC(=O)C[C@H]1S[C@H](c2ccccc2Cl)c2cc(Cl)ccc2NC1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)OC(=O)C[C@H]1S[C@H](c2ccccc2Cl)c2cc(Cl)ccc2NC1=S,,Cc1ccccc1,,,,val
+US20100305085A1,NNc1cc(Cl)ncn1.c1cc(N2CCCC2)ccn1>>NNc1cc(N2CCC(N3CCCC3)CC2)ncn1,,O,,,,val
+US20090170847A1,Cc1ccnc(N)c1N.O=C(O)c1ccc(F)cc1F>>Cc1ccnc2[nH]c(-c3ccc(F)cc3F)nc12,,O,,[Na+].[OH-],,val
+US20090324581A1,CI.O=Cc1c([N+](=O)[O-])ccc(OCc2ccccc2)c1O>>COc1c(OCc2ccccc2)ccc([N+](=O)[O-])c1C=O,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],val
+US20150018345A1,NCCN.O=C(Cl)OCc1ccccc1>>NCCNC(=O)OCc1ccccc1,,ClCCl,,,,val
+US20120157479A1,C=CCN(CC=C)C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CC=CC1,,ClCCl,,,,val
+US20010034343A1,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(C2C=NN=N2)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(C5C=NN=N5)ccc4OC)C3)CC2)nc2ccccc21,,CCOC(C)=O,CO,Cl,,val
+US20080280911A1,CCOC(=O)c1c[nH]c2c(F)cc(I)cc2c1=O>>O=C(O)c1c[nH]c2c(F)cc(I)cc2c1=O,,CO,,Cl,[Na+].[OH-],val
+US04814454,Nc1ccc(O)cc1.Oc1ccc2cc(Br)ccc2c1>>Oc1ccc(Nc2ccc3cc(Br)ccc3c2)cc1,,O,,O=S([O-])O.[Na+],,val
+US04052383,N=C(c1ccccc1)C1CCN1C(c1ccccc1)c1ccccc1.O=S(=O)(O)O>>O=C(c1ccccc1)C1CCN1C(c1ccccc1)c1ccccc1,,CO,,O=C([O-])O.[Na+],,val
+US20110053921A1,COC(=O)C(C)(C)N1C(=O)C2(C)COCCN2c2nc(Cl)ncc21>>CC(C)(C(=O)O)N1C(=O)C2(C)COCCN2c2nc(Cl)ncc21,,C1CCOC1,CO,[Na+].[OH-],,val
+US20090264431A1,CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Br)ccc2Br)C[C@@H]1CN.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Br)ccc2Br)C[C@@H]1CNC(=O)c1ccccc1,,ClCCl,,,,val
+US05314889,CC(=O)n1c(C(=O)O)cc2ccccc21.COc1sc(N)nc1-c1ccccc1>>COc1sc(NC(=O)c2cc3ccccc3[nH]2)nc1-c1ccccc1,,ClCCl,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,val
+US20130203768A1,CC(C)(C)OC(=O)N1CC[C@H](Nc2ccnc3ccccc23)C1>>c1ccc2c(N[C@H]3CCNC3)ccnc2c1,,ClCCl,O=C(O)C(F)(F)F,,,val
+US20040147535A1,COC(=O)c1ccccc1N.O=Cc1ccnc(Br)c1>>COC(=O)c1ccccc1NCc1ccnc(Br)c1,,CO,O,CC(=O)O,[BH3-]C#N.[Na+],val
+US20130102584A1,O=C(O)c1ccc(-c2ccccc2)cc1.c1cc(C2CNC2)ccn1>>O=C(c1ccc(-c2ccccc2)cc1)N1CC(c2ccncc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20070072920A1,COCCc1cc(OC)c(C[C@@H](C)NC(=O)C(F)(F)F)cc1OC.Cl>>COCCc1cc(OC)c(C[C@@H](C)N)cc1OC.Cl,,CCOCC,CO,[Na+].[OH-],,val
+US20060183769A1,CC(=O)OC(C)=O.Nc1ccc(-c2nc3c(C(=O)NC4CN5CCC4CC5)cccc3o2)cc1>>CC(=O)Nc1ccc(-c2nc3c(C(=O)NC4CN5CCC4CC5)cccc3o2)cc1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,c1ccncc1,,val
+US20090137564A1,CC(C)N=C=O.Oc1ccc(Cl)cc1F>>CC(C)NC(=O)Oc1ccc(Cl)cc1F,CN(C)c1ccncc1,C1CCOC1,,Cl,,val
+US20120058984A1,COc1ccc2nc(Nc3cc(C(F)(F)c4ccc(F)cc4)nc(Cl)n3)sc2c1.Nc1ccc(CC(=O)O)cc1>>COc1ccc2nc(Nc3cc(C(F)(F)c4ccc(F)cc4)nc(Nc4ccc(CC(=O)O)cc4)n3)sc2c1,Cl,CS(C)=O,,,,val
+US20110230486A1,CCc1ccc(Oc2cc(C)c(C(=O)CBr)c(C)c2)cc1.NC(N)=S>>CCc1ccc(Oc2cc(C)c(-c3csc(N)n3)c(C)c2)cc1,,CCO,,,,val
+US04278682,C1=C2c3[nH]c4ccccc4c3CCN2CCC1.C=CC(=O)OCC>>CCOC(=O)CCC1CCCN2CCc3c([nH]c4ccccc34)C12,,ClCCl,,CCO,,val
+US20130190297A1,CI.Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2nc(-c3ccc(F)cc3)[nH]c2n1>>Cn1c(-c2ccc(F)cc2)nc2c(N3CCN(C(=O)COc4ccc(Cl)cc4)CC3)nc(N)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US06627651B1,CCCOCc1ccccc1OB(O)O.COC(=O)C1=Cc2cc(O)ccc2S(=O)(=O)CC1>>CCCOCc1ccccc1Oc1ccc2c(c1)C=C(C(=O)OC)CCS2(=O)=O,,CCN(CC)CC,,ClCCl,,val
+US20160166560A1,COc1cccc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(O)cc4)c3)CC2)c1.NS(=O)(=O)Cl>>COc1cccc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(OS(N)(=O)=O)cc4)c3)CC2)c1,,CC(=O)N(C)C,,,,val
+US20030083333A1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccoc(=O)c2)c2ccccc12.Cl>>Cl.Nc1ccc(Oc2ccoc(=O)c2)c2ccccc12,,C1COCCO1,CCOCC,,,val
+US20090124802A1,Nc1cc(O)nc(N)n1.O=CCCl>>Nc1nc2[nH]ccc2c(=O)[nH]1,,O,,CC(=O)[O-].[Na+],,val
+US20050256103A1,CC(C)=CC(=O)O.Oc1cc(O)cc(O)c1>>CC1(C)CC(=O)c2c(O)cc(O)cc2O1,,CS(=O)(=O)O,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,val
+US05872118,O=C(O)CC(CC(=O)O)c1cccc(F)c1>>O=C(O)CC1CC(=O)c2ccc(F)cc21,,O,,,,val
+US20150183791A1,CC(=O)c1ccc(B(O)O)s1.Clc1ccc2ncc(Br)n2n1>>CC(=O)c1ccc(-c2cnc3ccc(Cl)nn23)s1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,O,O=C([O-])[O-].[K+].[K+],,val
+US04983597,CC[C@@H]1C(=O)N(S(=O)(=O)c2ccccc2C)[C@@H]1CO.COc1ccc(CC(=O)O)cc1>>CC[C@@H]1C(=O)N(S(=O)(=O)c2ccccc2C)[C@@H]1COC(=O)Cc1ccc(OC)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,val
+US04966905,CC1=CC(=O)C(C)(C)O1.O=CC=Cc1ccc(Cl)cc1>>CC1(C)OC(C=CC=Cc2ccc(Cl)cc2)=CC1=O,,CCO,,[Na+].[OH-],,val
+US04177274,Nc1ccc(I)cn1.Sc1ccccc1>>Nc1ccc(Sc2ccccc2)cn1,[Cu],CO,,C[O-].[Na+],,val
+US20150225412A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CNc1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCC[C@@H]1CNc1ccccc1N,[Pd],CO,,,,val
+US20040092556A1,COC(=O)c1ccc(CNc2cccc3cccnc23)cc1>>O=C(O)c1ccc(CNc2cccc3cccnc23)cc1,,C1CCOC1,CO,[Na+].[OH-],,val
+US20130143870A1,CN(C)C=O.Cl.O=C1CCCN(Cc2ccccc2)CC1.O=P(Cl)(Cl)Cl>>Cl.O=CC1=C(Cl)CCN(Cc2ccccc2)CC1,,ClCCl,,,,val
+US20080280925A1,COc1ccccc1CNC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CNC(=O)[C@H](C)NC(=O)OC(C)(C)C)n1>>COc1ccccc1CNC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CNC(=O)[C@H](C)N)n1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20140031364A1,COC(=O)CC#N.ON=C(Cl)c1ccccc1OC(F)(F)F>>COC(=O)c1c(-c2ccccc2OC(F)(F)F)noc1N,,CO,,C[O-].[Na+],,val
+US20080188521A1,CCC(OC(=O)c1ccc([N+](=O)[O-])cc1)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)cc(Cl)nc3c2)nn1)C(F)(F)F>>CC[C@](O)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)cc(Cl)nc3c2)nn1)C(F)(F)F,,C1CCOC1,,O,[Li+].[OH-],val
+US20100179128A1,Nc1ccccc1O.O=C(Cl)CCCCCCl>>O=C(CCCCCCl)Nc1ccccc1O,,CCOC(C)=O,,CCN(CC)CC,,val
+US04017298,CC(C(=O)C1CCCCC1)C(=O)C1CCCCC1.CNN>>Cc1c(C2CCCCC2)nn(C)c1C1CCCCC1,,O,,CC(C)O,,val
+US05556864,BrCC1CO1.N#Cc1ccccc1CCCCc1ccccc1O>>N#Cc1ccccc1CCCCc1ccccc1OCC1CO1,,CC(=O)N(C)C,,CC(C)(C)[O-].[K+],,val
+US20150299189A1,COC(=O)c1cc(C2CC2)ccc1Nc1ccc([N+](=O)[O-])c(CC(=O)OC(C)(C)C)c1>>COC(=O)c1cc(C2CC2)ccc1Nc1ccc(N)c(CC(=O)OC(C)(C)C)c1,[Fe],O,,CCO,[Cl-].[NH4+],val
+US06399660B1,CCOC(=O)COc1ccc(CCBr)c(Cl)c1.C[C@H](N)[C@H](O)c1ccc(O)cc1>>CCOC(=O)COc1ccc(CCN[C@@H](C)[C@H](O)c2ccc(O)cc2)c(Cl)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,val
+US06340679B1,CCOC(=O)CCCOc1ccc(C[C@H](NS(=O)(=O)c2ccc(C)cc2)C(=O)OC(C)(C)C)cc1.NC1=NCCCN1>>Cc1ccc(S(=O)(=O)N[C@@H](Cc2ccc(OCCCC(=O)NC3=NCCCN3)cc2)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,,,val
+US06013662,COc1ccccc1C1CCC(=O)CC1(O)C(=O)O>>COc1ccccc1C1CCC(=O)C=C1C(=O)O,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,val
+US20120058997A1,FC(F)(F)Oc1cccc(-c2cnc3ccc(Cl)nn23)c1.OCC1CCOCC1>>FC(F)(F)Oc1cccc(-c2cnc3ccc(COC4CCOCC4)nn23)c1,,C1COCCO1,,CC(C)(C)[O-].[K+],,val
+US20130178625A1,COc1cccc(-n2c(=O)c(=O)[nH]c3c4ccccc4ccc32)c1>>O=c1[nH]c2c3ccccc3ccc2n(-c2cccc(O)c2)c1=O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],val
+US20060009511A9,NCCc1c[nH]c2cc(C(F)(F)F)ccc12.O=C(O)C(=O)O>>NCCc1c[nH]c2cc(C(F)(F)F)ccc12.O=C(O)C(=O)O,,CC(C)=O,,CCOCC,,val
+US20100056527A1,CCOC(=O)c1cccc(Cc2cc(Cl)cc3cc(-c4ccccc4)oc23)n1>>O=C(O)c1cccc(Cc2cc(Cl)cc3cc(-c4ccccc4)oc23)n1,,CCO,,[Na+].[OH-],,val
+US20130072473A1,CC(C)(C)OC(=O)N1CCc2c(sc(NC(=O)c3ccccc3Cl)c2C(N)=O)C1.O=C(O)C(F)(F)F>>NC(=O)c1c(NC(=O)c2ccccc2Cl)sc2c1CC[NH2+]C2.O=C([O-])C(F)(F)F,,ClCCl,,,,val
+US04596680,O=C(Oc1ccccc1)c1ccccc1Oc1ccc([N+](=O)[O-])cc1>>Nc1ccc(Oc2ccccc2C(=O)Oc2ccccc2)cc1,[Pd],CCO,,[H][H],,val
+US20150203515A1,COC(=O)c1ccc2c(C(F)(F)F)c(O[C@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1>>O=C(O)c1ccc2c(C(F)(F)F)c(O[C@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1,,CO,,[Na+].[OH-],,val
+US20150166564A1,C[N+](=O)[O-].O=Cc1ccc(F)cc1>>O=[N+]([O-])/C=C/c1ccc(F)cc1,,CC(=O)O,,C,O=C[O-].[NH4+],val
+US20160206616A1,CCOC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl.O=C(O)CC[C@H]1CCC(F)(F)CN1>>CCOC(=O)C1=C(CN2CC(F)(F)CC[C@@H]2CCC(=O)O)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],val
+US20090221645A1,O=C(c1cccc2ccccc12)C(Br)COCc1ccccc1.S=C1NCCN1>>COCC1=C(c2cccc3ccccc23)N2CCN=C2S1,,CC(=O)O,,CO,,val
+US20120190665A1,COc1ncc(Cl)cc1-c1c(NC(=O)OC(C)(C)C)cnn1COCC[Si](C)(C)C>>COc1ncc(Cl)cc1-c1[nH]ncc1N,,CCOC(C)=O,,Cl[Sn](Cl)(Cl)Cl,,val
+US20120157436A1,CC(=O)CCl.CCOC(=O)C(N)=S>>CCOC(=O)c1nc(C)cs1,,CCO,,,,val
+US20050032873A1,CC=O.NC(=O)c1cccc2c1CC(NCCCc1c[nH]c3ccc(F)cc13)CO2>>CCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2cccc(C(N)=O)c2C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],val
+US20040209928A1,CC(C)(C)NC1CCCCC1.CCOC(=O)C(C)NC(=O)c1ccc(C(Br)CO[Si](C)(C)C(C)(C)C)cc1>>CCOC(=O)CCNC(=O)c1ccc(C(CO[Si](C)(C)C(C)(C)C)NC2CCC(C(C)(C)C)CC2)cc1,,CS(C)=O,O,CCOC(C)=O,,val
+US20030013721A1,Nc1ccccc1Cl.O=C(Cl)CCl>>O=C(CCl)Nc1ccccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US20080139390A1,BrC(Br)(Br)Br.Cc1nsc(C#N)c1CO>>Cc1nsc(C#N)c1CBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,val
+US20110217311A1,COC(=O)c1sc2ncnc(Nc3ccc(F)cc3O[C@H]3CCCC[C@@H]3OC)c2c1C>>CO[C@H]1CCCC[C@@H]1Oc1cc(F)ccc1Nc1ncnc2sc(C(=O)O)c(C)c12,,C1CCOC1,CO,Cl,[Na+].[OH-],val
+US20130303524A1,O=[N+]([O-])c1cccc(F)c1-c1ccc(F)cc1>>Fc1ccc2c(c1)[nH]c1cccc(F)c12,,Clc1ccccc1Cl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,val
+US20090124596A1,CC(C)(C)OC(=O)N1CCN(CC(=O)N[C@@H]2CC[C@H](n3c(=O)c4cc(F)cnc4n(-c4cccc(-c5ccccc5)c4)c3=O)CC2)CC1>>O=C(CN1CCNCC1)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccccc4)c3)c2=O)CC1,,C1COCCO1,,Cl,,val
+US20110009417A1,O=P(Br)(Br)Br.O=c1c(O)nc2cccnc2n1CC1CC1>>O=c1c(Br)nc2cccnc2n1CC1CC1,,CC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,val
+US20110312935A1,CCOC(=O)c1ccc(N)c(N)c1.S=C=Nc1c(Cl)cccc1Cl>>CCOC(=O)c1ccc2[nH]c(Nc3c(Cl)cccc3Cl)nc2c1,,CN(C)C=O,,CC(C)N=C=NC(C)C,,val
+US04450169,COC(=O)/C=C/[C@H]1[C@@H](C(=O)O)C1(C)C.OCc1cnc(Oc2ccccc2)s1>>COC(=O)/C=C/[C@H]1[C@@H](C(=O)OCc2cnc(Oc3ccccc3)s2)C1(C)C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,val
+US20100056531A1,C1CCOC1.ClCCl.NC(=O)CCC(=O)NCl.O=S=O.[Li]CCCC>>O=S(=O)(Cl)c1ccc2c(c1)OCC2,,ClCCl,,,,val
+US20020086890A1,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCNCC2)cc1.COc1ccc(C(=O)Cl)cc1>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCN(C(=O)c3ccc(OC)cc3)CC2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,CN(C)c1ccccn1,val
+US20150126449A1,Cc1ccc(Cl)c(C#N)c1F.NN>>Cc1ccc(Cl)c2c(N)n[nH]c12,,CCO,,O,,val
+US04411899,O=C1NC(=O)c2ccccc21.O=Cc1cccc(OCC(O)CCl)c1>>O=Cc1cccc(OCC(O)CN2C(=O)c3ccccc3C2=O)c1,,CCOCC,CN(C)C=O,[K],,val
+US20090163709A1,Brc1ccc2cc(OCc3ccccc3)ccc2c1.COc1ccc(CN)cc1>>COc1ccc(CNc2ccc3cc(OCc4ccccc4)ccc3c2)cc1,,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],val
+US05516629,BrBr.O=c1ccc2ccc(OCCCBr)cc2o1>>O=c1oc2cc(OCCCBr)ccc2cc1Br,,C1CCOC1,,,,val
+US20120115850A1,CS(=O)(=O)c1ccc(F)cc1F.NC1CCOc2ccccc21>>CS(=O)(=O)c1ccc(F)cc1NC1CCOc2ccccc21,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,val
+US05686424,C/C(=C\c1ccccc1)CO.CC[C@H](C)[C@H](N)C(=O)N(Cc1ccccc1)C(=O)[C@@H]1CCCN1CC(=O)O>>CC[C@H](C)[C@H](N)C(=O)N(Cc1ccccc1)C(=O)[C@@H]1CCCN1CC(=O)OCC=C(C)c1ccccc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,val
+US20050065066A1,N#CCS(=O)(=O)c1ccccc1.O=Cc1ccc(OCC(=O)O)cc1.[N-]=[N+]=[N-]>>N#Cc1[nH]nnc1-c1ccc(OCC(=O)O)cc1,,CCO,CN(C)C=O,O,,val
+US06329380B1,CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CCCNC1.COP(=O)(Cl)OC>>COP(=O)(OC)N1CCCC(C(C)Nc2nccc(-n3cnc4ccccc43)n2)C1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,val
+US20060100194A1,Brc1ccccc1.O=C1CCC(=O)c2ccc(Cl)cc2N1>>O=C1CCC(=O)N(c2ccccc2)c2cc(Cl)ccc21,[Cu]I,Cc1ccccc1,,CNCCNC,O=C([O-])[O-].[K+].[K+],val
+US20060211706A1,CC(C)(C)OC(=O)Nc1cccc(COS(C)(=O)=O)c1.c1c[nH]cn1>>CC(C)(C)OC(=O)Nc1cccc(Cn2ccnc2)c1,,CN(C)C=O,,[Na],,val
+US20100261698A1,CCCC(=O)Cl.Cn1c(-c2cncc(CN)c2)c(C#N)c2ccc(Cl)cc21>>CCCC(=O)NCc1cncc(-c2c(C#N)c3ccc(Cl)cc3n2C)c1,,ClCCl,,CCN(CC)CC,,val
+US20160229814A1,CC(C)N.COC(=O)c1cc([N+](=O)[O-])ccc1F>>COC(=O)c1cc([N+](=O)[O-])ccc1NC(C)C,,CC#N,,O,,val
+US04863947,COC(=O)C1(C)CNN=C1c1ccc(Cl)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>COC(=O)C1(C)CN(C(=O)Nc2ccc(C(F)(F)F)cc2)N=C1c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,Cl,val
+US08835458B2,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O.OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,val
+US20080009530A1,CCOC(=O)/C=C/c1ccc(OCCO[Si](C(C)C)(C(C)C)C(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CC(C)[Si](OCCOc1ccc(/C=C/C(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1)(C(C)C)C(C)C,,CCO,,C1CCOC1,[Na+].[OH-],val
+US05236937,CCc1cc(N)c(I)c(CC)n1.O=[N+]([O-])c1ccc(-n2nnnc2-c2ccccc2-c2ccc(CBr)cc2)cc1>>CCc1cc(NCc2ccc(-c3ccccc3-c3nnnn3-c3ccc([N+](=O)[O-])cc3)cc2)c(I)c(CC)n1,,C1CCOC1,,CC(C)(C)[O-].[K+],,val
+US20090137607A1,BrP(Br)Br.CC(O)c1ccc(-c2nc3nccn3cc2-c2ccccc2)cc1>>CC(Br)c1ccc(-c2nc3nccn3cc2-c2ccccc2)cc1,,ClCCl,,,,val
+US20070049581A1,CC(C)(C)OC(=O)COC1CCNCC1.O=C1CCN(C(=O)OCc2ccccc2)CC1>>CC(C)(C)OC(=O)COC1CCN(C2CCN(C(=O)OCc3ccccc3)CC2)CC1,,C1CCOC1,CCOC(C)=O,[Na+].[OH-],,val
+US20110269742A1,COC(=O)C1CCN(S(=O)(=O)c2ccc(-c3ccccn3)cc2)CC1>>O=C(O)C1CCN(S(=O)(=O)c2ccc(-c3ccccn3)cc2)CC1,,Cl,,,,val
+US05656626,COc1c(C=C(C)C(=O)OC(C)(C)C)c(=O)c2ccc(Cl)cc2[nH]c1=O>>COc1c(/C=C(\C)C(=O)O)c(=O)c2ccc(Cl)cc2[nH]c1=O,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20140213578A1,NCCN1c2ccccc2CCc2ccc(Cl)cc21.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>O=S(=O)(NCCN1c2ccccc2CCc2ccc(Cl)cc21)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,val
+US20110059951A1,CC(O)CN1CCN(C(=O)OCc2ccccc2)CC1.CS(=O)(=O)Cl>>CC(CN1CCN(C(=O)OCc2ccccc2)CC1)OS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US06723716B1,O=S(Cl)Cl.OCc1ncccc1SC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cl.ClCc1ncccc1SC(c1ccccc1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,,,val
+US20030130518A1,COCCc1nc2c(N)nc3c(c2n1CCOCCN)CCCC3.O=C=Nc1ccccc1>>COCCc1nc2c(N)nc3c(c2n1CCOCCNC(=O)Nc1ccccc1)CCCC3,,ClCCl,,CCN(CC)CC,,val
+US20080051419A1,CN(C)C=O.Cc1c[nH]c2ncnc(Cl)c12>>O=Cc1c[nH]c2ncnc(Cl)c12,,C1CCOC1,,[Li]CCCC,,val
+US20130096149A1,CC(C)(C)C(=O)Cl.COC(=O)c1cccc(N)c1Cl>>COC(=O)c1cccc(NC(=O)C(C)(C)C)c1Cl,,CCOC(C)=O,ClCCl,CCN(CC)CC,,val
+US20090227575A1,Clc1nc(N2CCOCC2)c2ccc3c(ccn3Cc3ccccc3)c2n1.OB(O)c1cccc(O)c1>>Oc1cccc(-c2nc(N3CCOCC3)c3ccc4c(ccn4Cc4ccccc4)c3n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,val
+US20140051846A1,COC(CN)OC.O=C1N[C@H]2CS[C@@H](CCCCC(=O)Oc3ccccc3[N+](=O)[O-])[C@H]2N1>>COC(CNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)OC,,CC#N,,CCN(CC)CC,,val
+US20110021537A1,CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)C1>>O=C(NC1CCNC1)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20070105904A1,CCCC[Sn](CCCC)(CCCC)c1cnn(Cc2ccc(OCc3ccccc3)cc2)c1.Nc1ncccc1Br>>Nc1ncccc1-c1cnn(Cc2ccc(OCc3ccccc3)cc2)c1,[Cu]I,C1CCOC1,,CCOC(C)=O,O,val
+US20130274243A1,CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)O.CC(C)(C)c1ccc(N)c(N)c1>>CC(C)(C)c1ccc2[nH]c([C@@H](N)C(C)(C)O)nc2c1,,C1COCCO1,CCOC(C)=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,val
+US04894302,BrB(Oc1ccccc1)Oc1ccccc1.C1CCOC1>>BrB(Oc1ccccc1)Oc1ccccc1.C1CCOC1,,C1CCOC1,,,,val
+US20130023502A1,CC(=O)N(C(C)=O)c1c([N+](=O)[O-])cc([N+](=O)[O-])cc1C(F)(F)F>>Cc1nc2cc(N)cc(C(F)(F)F)c2[nH]1,[Pd],CC(=O)O,,[H][H],,val
+US20030207877A1,BrBr.CC(=O)c1ccc(C)o1>>Cc1ccc(C(=O)CBr)o1,,C1COCCO1,CCOCC,[Cl-].[NH4+],,val
+US07071201B2,CC(=O)Nc1ccc(CCN2CCC(N3CCc4ccccc43)CC2)cc1>>CCNc1ccc(CCN2CCC(N3CCc4ccccc43)CC2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],val
+US20070027112A1,C=CCCCC(=O)c1ccc(-c2ccccc2)cc1>>C=CCCCC(O)c1ccc(-c2ccccc2)cc1,,CCOCC,,O,,val
+US04013645,CSCC1=C(C(=O)O)N2C(=O)[C@@H](NC=O)[C@H]2SC1.Cl>>CSCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1.Cl,,C1COCCO1,,,,val
+US20110065691A1,Brc1ccc2[nH]nc(C3CCC3)c2c1.CCI>>CCn1nc(C2CCC2)c2cc(Br)ccc21,,CN(C)C=O,,[H-].[Na+],,val
+US20160176868A1,CCn1c(=O)[nH]c2c(c1=O)C(=O)C[C@H](c1cccc(Cl)c1)N2>>CCn1c(=O)[nH]c2c(c1=O)CC[C@H](c1cccc(Cl)c1)N2,,C1CCOC1,,[BH4-].[Li+],,val
+US05374625,COCCOc1nc(N)nc2c1ncn2[C@@H]1C[C@H](COC(=O)c2ccccc2)[C@@H](COC(=O)c2ccccc2)C[C@H]1O>>Nc1nc2c(ncn2[C@@H]2C[C@H](CO)[C@@H](CO)C[C@H]2O)c(=O)[nH]1,,CO,,Cl,C[O-].[Na+],val
+US20070197478A1,CCOC(=O)N(Cc1ccccc1)c1cc(Br)nc(N)c1[N+](=O)[O-].CN>>CCOC(=O)N(Cc1ccccc1)c1cc(NC)nc(N)c1[N+](=O)[O-],,C1CCOC1,,,,val
+US20120115903A1,CCOC(C)=O.CI.COc1ccc2[nH]cc(CC(=O)O)c2c1>>COC(=O)Cc1cn(C)c2ccc(OC)cc12,,CC(C)=O,,[K+].[OH-],,val
+US05041462,CC(=O)OCC(=O)Cl.CCN(C)c1cccc(N)c1C#N>>CCN(C)c1cccc(NC(=O)COC(C)=O)c1C#N,,ClCCl,,O,c1ccncc1,val
+US20090163714A1,Clc1ncnc2[nH]ncc12.Fc1ccc(-c2cnc(N3CCNCC3)[nH]2)cc1C(F)(F)F>>Fc1ccc(-c2cnc(N3CCN(c4ncnc5[nH]ncc45)CC3)[nH]2)cc1C(F)(F)F,,CC(C)O,,CCN(C(C)C)C(C)C,,val
+US05298660,C[C@@H](N)c1ccc(Br)cc1.O=Cc1ccc(O)cc1>>CC(N=Cc1ccc(O)cc1)c1ccc(Br)cc1,,CCO,,,,val
+US20110301162A1,Clc1nnc(-c2ccccc2)c2ccccc12.Nc1ccc(O)cc1>>Cl.Oc1ccc(Nc2nnc(-c3ccccc3)c3ccccc23)cc1,,c1ccccc1,,CCOCC,,val
+US20120035196A1,CCC(=O)NCCCOc1cc(C)c(-c2cccc(CO)c2C)c(C)c1.ClCCl>>CCC(=O)N(C)CCCOc1cc(C)c(-c2cccc(CO)c2C)c(C)c1,,ClCCl,,CCN(CC)CC,C[Si](C)(C)Cl,val
+US20090275570A1,CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3cc(-c4cccc(F)c4)sc23)C1>>NC(=O)c1cnc(N[C@H]2CCCNC2)c2sc(-c3cccc(F)c3)cc12,,O,,[Na+].[OH-],,val
+US20060276465A1,Cc1nc2cc(C3=CCC(C(C)(C)C)CC3)c([N+](=O)[O-])cc2s1>>Cc1nc2cc(C3=CCC(C(C)(C)C)CC3)c(N)cc2s1,[Pd],CO,,,,val
+US20070185079A1,COc1ccc2c(C)cc(N[C@H]3CC[C@H](N)C3)nc2c1.O=Cc1ccn(-c2ccc(C(F)(F)F)cc2)c1>>COc1ccc2c(C)cc(N[C@H]3CC[C@H](NCc4ccn(-c5ccc(C(F)(F)F)cc5)c4)C3)nc2c1,,ClCCl,,,,val
+US20110009454A1,N#Cc1ccc(F)cc1.Oc1ccc2ccccc2c1>>N#Cc1ccc(Oc2ccc3ccccc3c2)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],val
+US20030064987A1,BrCc1ccccc1.NC1CCC(=O)NC1=O>>O=C1CCC(NCc2ccccc2)C(=O)N1,,CCN(CC)CC,,,,val
+US20060111362A1,CC#CCn1c(=O)[nH]c2nc(Cl)nc(Cl)c21.CC(C)(C)C(=O)OCCl>>CC#CCn1c(=O)n(COC(=O)C(C)(C)C)c2nc(Cl)nc(Cl)c21,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],val
+US20150238601A1,CC(C)NC(=O)COc1cccc(B2OC(C)(C)C(C)(C)O2)c1.Clc1cc(Cl)nc(I)n1>>CC(C)NC(=O)COc1cccc(-c2nc(Cl)cc(Cl)n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,val
+US20070197635A1,CC1(CCC2=C3CCC4(C)C(=O)CCC4C3OCC2=O)OCCO1>>CC(=O)CCC1=C2CCC3(C)C(=O)CCC3C2OCC1=O,,CC(C)=O,,Cl,,val
+US20030022887A1,COc1cc2cc(CO)ccc2c(OC)c1OC>>COc1cc2cc(C=O)ccc2c(OC)c1OC,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,val
+US20080085890A1,CC(C)I.O=C1NC(=O)c2ccc(Br)cc2/C1=C/NCc1ccc(O)c(O)c1>>CC(C)Oc1ccc(CN/C=C2\C(=O)NC(=O)c3ccc(Br)cc32)cc1O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20100009969A1,C[C@@H]1CCCN1CCCOc1ccc(-c2nc3c(s2)CNCC3)cc1.NC(=O)CBr>>C[C@@H]1CCCN1CCCOc1ccc(-c2nc3c(s2)CN(CC(N)=O)CC3)cc1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],val
+US20140315888A1,COC(OC)OC.NNc1nc2cc(Br)cnc2nc1N1CCN2CCCC2C1>>Brc1cnc2nc(N3CCN4CCCC4C3)c3nncn3c2c1,,CCOCC,,,,val
+US20140274933A1,COc1ccc2c(-c3cccc(F)c3)nn(CC(=O)N(C)c3ccc4nc(C)oc4c3)c(=O)c2c1>>Cc1nc2ccc(N(C)C(=O)Cn3nc(-c4cccc(F)c4)c4ccc(O)cc4c3=O)cc2o1,,ClCCl,O,BrB(Br)Br,O=C([O-])O.[Na+],val
+US20090156646A1,CCNC(CC)CC(=O)Nc1cccc(-c2cc(-c3ccc(F)cc3O)nc(NC(=O)c3ccco3)c2C#N)c1.Cl>>CCNC(CC)CC(=O)Nc1cccc(-c2cc(-c3ccc(F)cc3O)nc(NC(=O)c3ccco3)c2C#N)c1.Cl,,CCOC(C)=O,,,,val
+US20080312192A1,CN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.O=C=Nc1ccc(Oc2cc(Cl)ncn2)cc1>>CN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(Cl)ncn4)cc3)cc2C(F)(F)F)CC1,,C1CCOC1,CCOCC,,,val
+US20160185769A1,CS(=O)(=O)c1ccc(F)c(Br)c1.Cc1cccc(C)c1O>>Cc1cccc(C)c1Oc1ccc(S(C)(=O)=O)cc1Br,,CS(C)=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],val
+US06498165B1,CO.C[Si](C)(C)C=[N+]=[N-].O=C(O)c1cc2nc[nH]c2cc1C(=O)O>>COC(=O)c1cc2nc[nH]c2cc1C(=O)OC,,CCOC(C)=O,,CCOCC,O,val
+US20120288492A1,COc1cnc(-c2ccc(O)cc2)nc1N1CCOCC1.O=C=Nc1ccccc1>>COc1cnc(-c2ccc(OC(=O)Nc3ccccc3)cc2)nc1N1CCOCC1,,C1COCCO1,,,,val
+US06313137B1,CCc1cccc(C)c1COC(=O)c1cnc([N+](=O)[O-])c(OCc2c(C)cccc2CC)c1.N>>CCc1cccc(C)c1COc1cc(C(N)=O)cnc1N,,CO,,,,val
+US06063782,CC=CCn1c(C)c(C)c2cnnc(OCc3ccc(F)cc3)c21.O=C(OO)c1cccc(Cl)c1>>CC=CCn1c(C)c(C)c2c[n+]([O-])nc(OCc3ccc(F)cc3)c21,,ClCCl,,,,val
+US20060089344A1,CN.NC(=O)COC(=O)NCCC1CCN(c2cccc(C(F)(F)F)c2)CC1.O=C1COC(=O)N1CCC1CCN(c2ccc3ccccc3n2)CC1>>CNC(=O)COC(=O)NCCC1CCN(c2ccc3ccccc3n2)CC1,,C1CCOC1,,,,val
+US20150111869A1,COC(CC(=O)NN)c1ccc(Cl)cc1.Cn1nccc1Nc1nccc(-c2cnnc(Cl)c2)n1>>COC(Cc1nnc2cc(-c3ccnc(Nc4ccnn4C)n3)cnn12)c1ccc(Cl)cc1,,CC(C)O,,CS(=O)(=O)O,,val
+US20150353548A1,CCI.O=S1(=O)NCc2cc(Br)ccc21>>CCN1Cc2cc(Br)ccc2S1(=O)=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],val
+US06433225B1,COCCCC/C(=N\OCCN)c1ccc(C(F)(F)F)cc1.O=C(O)/C=C\C(=O)O>>COCCCC/C(=N\OCCN)c1ccc(C(F)(F)F)cc1.O=C(O)/C=C\C(=O)O,,O,,,,val
+US06008230,C=C(C)C(=O)O.NNc1ccnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc12>>C=C(C)C(=O)NNc1ccnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc12,,CCOC(C)=O,CN(C)C=O,On1nnc2ccccc21,,val
+US20040030178A1,COC(=O)CCCCC(=O)C1CO1>>COC(=O)CCCCC(=O)CCO,O=[Pt]=O,CCOC(C)=O,,,,val
+US20090076074A1,COc1cc2nccc(Oc3ccc(CC(=O)O)cc3)c2cc1OC.O=C(Cl)C(=O)Cl>>COc1cc2nccc(Oc3ccc(CC(=O)Cl)cc3)c2cc1OC,,ClC(Cl)Cl,,,,val
+US05885984,CCOCC.Cl.O=C(Cl)Cc1ccc([N+](=O)[O-])cc1.O=C(O)Cc1ccc([N+](=O)[O-])cc1>>Cl.O=C(O)C(c1ccc([N+](=O)[O-])cc1)[C@@H]1CCCC[C@H]1N1CCOCC1,,ClC(Cl)Cl,,,,val
+US20110112140A1,O=[N+]([O-])c1cccc(Cc2ccco2)c1>>Nc1cccc(Cc2ccco2)c1,,CCO,,Cl,O=C([O-])O.[Na+],val
+US20160002177A1,COc1cc(Br)c(C(F)(F)F)c2c(=O)[nH]cnc12>>O=c1[nH]cnc2c(O)cc(Br)c(C(F)(F)F)c12,,ClCCl,,BrB(Br)Br,,val
+US20100063101A1,CCOC(=O)C(Br)C1CCCCC1.Clc1ccc(-c2nc3ccccc3[nH]2)cc1>>CCOC(=O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20060014826A1,CC1(c2ccccc2)CCC(=O)CC1=O.O=C=Nc1cccc(C(F)(F)F)c1>>CC1(c2ccccc2)CCC(=O)C(C(=O)Nc2cccc(C(F)(F)F)c2)C1=O,,CN(C)C=O,,[H-].[Na+],,val
+US04507498,CCCc1c(OCCCCCC(=O)OC)ccc(C(C)=O)c1O.CS(=O)(=O)OCCOCCOS(C)(=O)=O>>CCCc1c(OCCCCCC(=O)OC)ccc(C(C)=O)c1OCCOCCOS(C)(=O)=O,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,val
+US20090023763A1,CSc1nccc(-c2cc([N+](=O)[O-])c(N)nc2-c2ccco2)n1>>CSc1nccc(-c2cc(N)c(N)nc2-c2ccco2)n1,[Fe],CCO,,Cl,,val
+US20120214802A1,C[N+](=O)[O-].O=Cc1ccccc1>>O=[N+]([O-])CCc1ccccc1,,CO,O,Cl,[Na+].[OH-],val
+US20120329649A1,Cc1cc(/C=C/C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1C(=O)NCC(=O)NNC(=O)C1CC1>>Cc1cc(/C=C/C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1C(=O)NCc1nnc(C2CC2)o1,,O=P(Cl)(Cl)Cl,,,,val
+US20090149456A1,COc1ccc2c(-c3ccnc(Nc4cccc(OCCN(C)C)c4)n3)c(-c3cccc(N)c3)nn2c1.O=C(O)C1(c2ccccc2)CC1>>COc1ccc2c(-c3ccnc(Nc4cccc(OCCN(C)C)c4)n3)c(-c3cccc(NC(=O)C4(c5ccccc5)CC4)c3)nn2c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20150376181A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncnc(NC(=O)C2CC2)c1F>>Nc1ncnc(NC(=O)C2CC2)c1F,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20050107345A1,CCCCCCCCCCCCC(CCP(=O)(OCC)OCC)NC(=O)OCc1ccccc1>>CCCCCCCCCCCCC(N)CCP(=O)(O)O,,ClCCl,,C[Si](C)(C)I,,val
+US04409017,CCOC(=O)C(C)(C)Br.CN(c1ccc(O)cc1)c1cc2ccc(Cl)cc2c(Cl)n1>>CCOC(=O)C(C)(C)Oc1ccc(N(C)c2cc3ccc(Cl)cc3c(Cl)n2)cc1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,val
+US20150166558A1,CC(C)(C)OC(=O)N[C@@H](CO)c1ccc(O)cc1.CCOC(=O)CBr>>CCOC(=O)COc1ccc([C@H](CO)NC(=O)OC(C)(C)C)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US06130339,CCCC[Sn](CCCC)(CCCC)c1scc2c1OCCO2.O=[N+]([O-])c1ccc(Br)cc1>>O=[N+]([O-])c1ccc(-c2scc3c2OCCO3)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,val
+US05594081,CC(=O)c1ccc(C)cc1.Cc1ccc(C=O)cc1>>Cc1ccc(C=CC(=O)c2ccc(C)cc2)cc1,,CCO,O,[Na+].[OH-],,val
+US20160145192A1,O=C(OCCCCO)c1ccc([N+](=O)[O-])cc1.O=[N+]([O-])O>>O=C(OCCCCO[N+](=O)[O-])c1ccc([N+](=O)[O-])cc1,,CC(=O)OC(C)=O,,,,val
+US20020183512A1,BrCCCCCBr.Cc1cc(C)c(S(=O)(=O)Nc2c3ccccc3nc3ccccc23)c(C)c1>>Cc1cc(C)c(S(=O)(=O)N(CCCCCBr)c2c3ccccc3nc3ccccc23)c(C)c1,,CN(C)C=O,,[H-].[Na+],,val
+US20130338081A1,O=C1C[C@@H](C(=O)N[C@@H]2CCCc3ccccc32)N(C(=O)OCc2ccccc2)C1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C(N[C@@H]1CCCc2ccccc21)[C@@H]1C=C(OS(=O)(=O)C(F)(F)F)CN1C(=O)OCc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,val
+US04286089,CC(C)(C)OC(=O)C1=C(C(CCC(N)=O)Sc2nnn[nH]2)CS[C@@H]2C(N)C(=O)N12.O=C(O)CS(=O)(=O)CC(F)(F)F>>CC(C)(C)OC(=O)C1=C(C(CCC(N)=O)Sc2nnn[nH]2)CS[C@@H]2C(NC(=O)CS(=O)(=O)CC(F)(F)F)C(=O)N12,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,val
+US20010021718A1,CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20050208582A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.Fc1cc2[nH]nc(I)c2cc1Br>>Fc1cc2c(cc1Br)c(I)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],val
+US20110160198A1,BrP(Br)Br.Cc1c[n+]([O-])c(C)cc1[N+](=O)[O-]>>Cc1cc(Br)c(C)cn1,,CCOC(C)=O,,[Na+].[OH-],,val
+US20130178460A1,Cc1nc(NC(=O)c2csc3cnc(N[C@@H]4CCCC[C@@H]4NC(=O)OC(C)(C)C)nc23)ccc1C#N>>Cc1nc(NC(=O)c2csc3cnc(N[C@@H]4CCCC[C@@H]4N)nc23)ccc1C#N,,ClCCl,O=C(O)C(F)(F)F,,,val
+US20080139539A1,COc1ccc2ncc(F)c(N3CCN(CCNC(=O)OC(C)(C)C)CC3)c2n1>>COc1ccc2ncc(F)c(N3CCN(CCN)CC3)c2n1,,CO,,C1COCCO1,Cl,val
+US05545652,CCOC(=O)CNc1ccc(OCC(F)(F)C(F)F)cc1.O=C(Cl)CCl>>CCOC(=O)CN(C(=O)CCl)c1ccc(OCC(F)(F)C(F)F)cc1,,ClCCl,,CCN(CC)CC,,val
+US20070167482A1,COc1cc2c(cc1OC)C1CC(OC(C)=O)CCC1N=C2c1ccc(C(=O)N=C(N)N2CCN(C(C)=O)CC2)cc1>>COc1cc2c(cc1OC)C1CC(O)CCC1N=C2c1ccc(C(=O)N=C(N)N2CCN(C(C)=O)CC2)cc1,,CO,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20070049618A1,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1cccc(C(F)(F)F)c1F>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)c4cccc(C(F)(F)F)c4F)c3C2=O)C(=O)N1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,val
+US20100016315A1,BrBr.NC(=O)c1cc(Cl)cc(CO)c1>>NC(=O)c1cc(Cl)cc(CBr)c1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,val
+US20100035865A1,CCO.O=C1CCCO1>>CCOC(=O)CCCO,,CCOCC,,C1CCOC1,Cl,val
+US04837316,CCOC(=O)CSCc1ccco1.CO>>CCOC(=O)CS(=O)Cc1ccco1,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,val
+US20050004167A1,NN.O=C(O)c1ccc2oc3ccccc3c2c1>>NNC(=O)c1ccc2oc3ccccc3c2c1,,CCOC(C)=O,CN(C)C=O,CC(C)COC(=O)Cl,CN1CCOCC1,val
+US20050158863A1,CCCCN.Cc1n[nH]c(=S)[nH]c1=O>>Cc1nn(CCCCN)c(=S)[nH]c1=O,,CCO,,,,val
+US20140296064A1,CN(C)C(=O)Cl.Clc1csc(Cl)n1>>CN(C)C(=O)c1sc(Cl)nc1Cl,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,val
+US20160046597A1,Cn1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21>>Cn1cc(C2CCNCC2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21,,C1COCCO1,CO,Cl,O=C([O-])O.[Na+],val
+US20100210624A1,O=C(O)[C@H](O)[C@@H](O)C(=O)O.c1cnnc(-c2ccc3c(c2)CNCCC3Oc2ccc3ccccc3c2)c1>>O=C(O)C(O)C(O)C(=O)O.c1cnnc(-c2ccc3c(c2)CNCCC3Oc2ccc3ccccc3c2)c1,,CO,,O,,val
+US20120114696A1,COC(=O)Cc1ccsc1Br.O=C(Cl)c1ccc(I)c([N+](=O)[O-])c1>>COC(=O)Cc1cc(C(=O)c2ccc(I)c([N+](=O)[O-])c2)sc1Br,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,val
+US20120165305A1,N#C/C=C/C(F)(F)F.O=C(NCC(F)(F)F)Nc1cccc(-n2cnc3cc(-c4cn[nH]c4)ccc32)c1>>N#CCC(n1cc(-c2ccc3c(c2)ncn3-c2cccc(NC(=O)NCC(F)(F)F)c2)cn1)C(F)(F)F,,CC#N,,C1CCC2=NCCCN2CC1,Cl,val
+US20160115126A1,Cc1[nH]c2c(C(N)=O)cc(F)c(Br)c2c1C>>Cc1[nH]c2c(C#N)cc(F)c(Br)c2c1C,,C1CCOC1,,O=P(Cl)(Cl)Cl,,val
+US20080293687A1,CCNCCOCc1cnc(-c2ccc(C(=O)Nc3ccccc3NC(=O)OC(C)(C)C)cc2)c(C#N)c1>>CCNCCOCc1cnc(-c2ccc(C(=O)Nc3ccccc3N)cc2)c(C#N)c1,,C1COCCO1,,Cl,,val
+US20110152519A1,COc1ccc(C=Cc2nc(N3CCOCC3)c([N+](=O)[O-])c(N3CCOCC3)n2)cc1>>COc1ccc(C=Cc2nc(N3CCOCC3)c(N)c(N3CCOCC3)n2)cc1,[Zn],CC#N,O,[Ca+2].[Cl-].[Cl-],,val
+US20090181068A1,CCCCCCCCCCCCCCCC(=O)O.CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5>>CCCCCCCCCCCCCCCC(=O)[O-].CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5,,CN1CCCC1=O,,,,val
+US20010021777A1,CN=C=O.Clc1ccc2c(C3=CCN(CCC4CNc5ccccc54)CC3)c[nH]c2c1.O=C([O-])C(=O)[O-]>>CNC(=O)N1CC(CCN2CC=C(c3c[nH]c4cc(Cl)ccc34)CC2)c2ccccc21.O=C(O)C(=O)O,,ClCCl,,,,val
+US04954160,C=CCON=C(CC)C1=C(O)C(c2cccc(Cl)c2)C(C)(C)CC1=O.O=C(Cl)c1ccccc1>>C=CCON=C(CC)C1=C(OC(=O)c2ccccc2)C(c2cccc(Cl)c2)C(C)(C)CC1=O,,CC(C)=O,,[Na+].[OH-],,val
+US20100305133A1,COC(=O)c1c(OC)ccc([N+](=O)[O-])c1N.O=C(C(=O)c1ccccc1)c1ccccc1>>COC(=O)c1c(OC)ccc2nc(-c3ccccc3)c(-c3ccccc3)nc12,[Pd],CCOC(C)=O,,,,val
+US06476030B1,Cn1ncnc1CCl.Oc1nn2c(-c3ccccc3F)nncc2c1I>>Cn1ncnc1COc1nn2c(-c3ccccc3F)nncc2c1I,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],val
+US20110144194A1,COS(=O)(=O)OC.COc1ccc(-c2oc3cc(OC)c(I)c(O)c3c(=O)c2OC)cc1OC>>COc1ccc(-c2oc3cc(OC)c(I)c(OC)c3c(=O)c2OC)cc1OC,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,val
+US20100298336A1,Cn1cc(Cl)c(CBr)n1.Oc1cc(C(F)(F)F)nc(S)n1>>Cn1cc(Cl)c(CSc2nc(O)cc(C(F)(F)F)n2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20090118312A1,COC(=O)c1ccc(OC)c(C)c1N.O=C(Cl)c1ccccc1>>COC(=O)c1ccc(OC)c(C)c1NC(=O)c1ccccc1,,ClCCl,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,val
+US20140171403A1,CC(C)(C)OC(=O)NC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1>>NC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1,,ClCCl,,C1COCCO1,Cl,val
+US20050272794A1,CCOC(=O)c1ccc([C@H](C)n2nc(-c3cc(Cl)cc(Cl)c3)cc2OS(=O)(=O)C(F)(F)F)cc1.COc1ccc2cc(B(O)O)ccc2c1>>CCOC(=O)c1ccc([C@H](C)n2nc(-c3cc(Cl)cc(Cl)c3)cc2-c2ccc3cc(OC)ccc3c2)cc1,,COCCOC,,CCN(CC)CC,,val
+US20060025474A1,CCC(CC)(c1ccc(C#CCCCCC(=O)OC)c(C)c1)c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1>>CCC(CC)(c1ccc(C#CCCCCC(=O)O)c(C)c1)c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1,,CO,,CCOC(C)=O,[Na+].[OH-],val
+US20160221945A1,COCCOc1cc(-c2ccc(C(F)(F)F)nc2)cc(C#N)n1.Cl>>COCCOc1cc(-c2ccc(C(F)(F)F)nc2)cc(CN)n1.Cl,[Pd],CO,,,,val
+US20100137308A1,CN(C)CC(=O)O.COc1ccc(CC2CCNCC2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1.Cl>>COc1ccc(CC2CCN(C(=O)CN(C)C)CC2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1.Cl,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,,val
+US05318720,CC(=O)c1ccc(O)cc1.O=[N+]([O-])O>>CC(=O)c1ccc(O)c([N+](=O)[O-])c1,,O=S(=O)(O)O,,,,val
+US05948932,CCC(=O)C(C)=NOC.CCCCON=O>>CON=C(C)C(=O)C(C)=NO,,CO,,Cl,C[O-].[Na+],val
+US20130331419A1,CCC(/C=C/C#N)(c1ccc(Cl)cc1)n1ncc2c(N)cccc21.CS(=O)(=O)Cl>>CCC(/C=C/C#N)(c1ccc(Cl)cc1)n1ncc2c(NS(C)(=O)=O)cccc21,,ClCCl,,CN1CCOCC1,,val
+US20070225267A1,CC(=O)OC(C)=O.C[C@H]1[C@H](OCC(F)(F)F)OC[C@H]([C@@H](O)[C@@H](N)Cc2cc(O)cc(F)c2)N1C(=O)OC(C)(C)C>>CC(=O)N[C@@H](Cc1cc(O)cc(F)c1)[C@H](O)[C@H]1CO[C@@H](OCC(F)(F)F)[C@H](C)N1C(=O)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US06765114B1,O=C(CC1(C[N+](=O)[O-])CCCCC1)OCc1ccccc1>>NCC1(CC(=O)O)CCCCC1,[Pd],CO,,[H][H],,val
+US20110059043A1,CI.Oc1cc(Cl)cc(Cl)c1I>>COc1cc(Cl)cc(Cl)c1I,,CN(C)C=O,,,,val
+US20070249670A1,Cc1ccc(N)c(C(=O)O)c1.Cc1cccc(C)c1N=C=O>>Cc1ccc(NC(=O)Nc2c(C)cccc2C)c(C(=O)O)c1,,CN(C)C=O,O,CCN(CC)CC,Cl,val
+US20140206875A1,CI.COC(=O)C(C)(C)NS(=O)(=O)c1cccc2cccnc12>>COC(=O)C(C)(C)N(C)S(=O)(=O)c1cccc2cccnc12,,CN(C)C=O,,O,,val
+US20100331295A1,CC(=O)c1ccc(-c2cccc(S(C)(=O)=O)c2)s1.CCOC(=O)C(F)(F)F>>CS(=O)(=O)c1cccc(-c2ccc(C(=O)CC(=O)C(F)(F)F)s2)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,val
+US20130137680A1,Cn1cc(NC(=O)OC(C)(C)C)nc1C(=O)O.NC1CCCC1>>Cn1cc(NC(=O)OC(C)(C)C)nc1C(=O)NC1CCCC1,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,val
+US05192766,COC(=O)/C=C(/C#Cc1ccccc1)c1ccccc1>>O=C(O)/C=C(/C#Cc1ccccc1)c1ccccc1,,C1CCOC1,,CO,[Na+].[OH-],val
+US04360660,CN(C)c1ccc(C=O)cc1.CN(CCN(C)c1ccccc1)c1ccccc1>>c1ccc(C(c2ccccc2)c2ccccc2)cc1,,O,,[Na+].[OH-],,val
+US20130116235A1,CC1(C)Cc2cc3n(c2C1)CCN(c1nccc(Cl)c1C=O)C3=O>>CC1(C)Cc2cc3n(c2C1)CCN(c1nccc(Cl)c1CO)C3=O,,ClCCl,,CO,[BH4-].[Na+],val
+US20090042900A1,CC(C)(C)OC(=O)N1CCC(COc2cccc3nc(N)nc(N)c23)CC1>>Nc1nc(N)c2c(OCC3CCNCC3)cccc2n1,,C1COCCO1,,Cl,,val
+US20160158207A1,CNCCO.O=[N+]([O-])c1cc(C(F)F)c(Br)cc1F>>CN(CCO)c1cc(Br)c(C(F)F)cc1[N+](=O)[O-],,CN(C)C=O,,CCN(C(C)C)C(C)C,O,val
+US20020188009A1,Cc1nc(-c2ccccc2)c(-c2ccccc2)n1CCCCCC(C(=O)O)(C(=O)O)c1ccccc1>>Cc1nc(-c2ccccc2)c(-c2ccccc2)n1CCCCCC(C(=O)O)c1ccccc1,,CC(=O)O,,,,val
+US20040127538A1,CC(=O)O.N#Cc1ccc2[nH]nc(-c3cc4ccccc4s3)c2c1.O=S(=O)(O)O>>O=C(O)c1ccc2[nH]nc(-c3cc4ccccc4s3)c2c1,,CCOC(C)=O,,O,,val
+US08492414B2,COc1ccc(-c2nsc(CBr)n2)cc1.NC(=O)c1c(F)ccc(O)c1F>>COc1ccc(-c2nsc(COc3ccc(F)c(C(N)=O)c3F)n2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20090215803A1,CC(C)CCOc1ccccc1Br.CCOB(OCC)OCC>>CC(C)CCOc1ccccc1B(O)O,,C1CCOC1,,[Li]CCCC,,val
+US05426119,COC(=O)CCCC=C(c1cccnc1)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Br)cc1)C2>>O=C(O)CCCC=C(c1cccnc1)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Br)cc1)C2,,CCO,,,,val
+US20160136172A1,COc1ncc(Br)cc1C(=O)NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)c1cc(Br)cnc1O,,ClCCl,,BrB(Br)Br,CO,val
+US20150005300A1,BrCc1ccccc1.O=CC1(Br)C=C(O)C=CC1>>O=Cc1cc(OCc2ccccc2)ccc1Br,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],val
+US20140094475A1,Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1.O=C(O)/C=C/c1ccc(O)cc1>>Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1.O=C([O-])/C=C/c1ccc(O)cc1,,CO,,,,val
+US20120157439A1,CCCS(=O)(=O)Cl.COC(=O)c1cc(Cl)cc(N)c1F>>CCCS(=O)(=O)Nc1cc(Cl)cc(C(=O)O)c1F,,C1CCOC1,,CCN(CC)CC,[Na+].[OH-],val
+US20060217387A1,Cc1cc(-c2cc(C(F)(F)F)n3nccc3n2)ccc1Cl.ClI>>Cc1cc(-c2cc(C(F)(F)F)n3ncc(I)c3n2)ccc1Cl,,CC(=O)O,O,CC(=O)[O-].[Na+],,val
+US20080242694A1,C=Cc1cncc2ccc(-c3nnc(N[C@H](Cc4ccccc4)CN4C(=O)c5ccccc5C4=O)s3)nc12>>CCc1cncc2ccc(-c3nnc(N[C@@H](CN)Cc4ccccc4)s3)nc12,,CCO,,NN,,val
+US20090093473A1,CC(=O)O.COC(=O)C1CC(=O)C(N=Nc2ccccc2)=C(O)C1>>COC(=O)C1CC(=O)C(NC(C)=O)=C(O)C1,[Zn],CC(=O)O,,CC(=O)OC(C)=O,,val
+US09169295B2,C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)OC(C)(C)C>>C[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)OC(C)(C)C,,CN(C)C=O,,C1CCNCC1,,val
+US20070249688A1,CC(C)CC(Sc1ccc(Br)cc1)c1ccc(C(=O)O)cc1.COC(=O)CCN>>COC(=O)CCNC(=O)c1ccc(C(CC(C)C)Sc2ccc(Br)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,val
+US20160096839A1,C=CC[C@H](NC(=O)OC(C)(C)C)c1cc(-c2ccncc2NC(=O)[C@H](C)C=C)ccn1>>CC1C=CC[C@H](NC(=O)OC(C)(C)C)c2cc(ccn2)-c2ccncc2NC1=O,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,val
+US20090099169A1,Cc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12.Cl>>Cc1cc(C(=O)NC2CCNCC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12.Cl,,CCOCC,Cl,,,val
+US20020019434A1,CCOC(=O)C(O)=CC(=O)c1c[nH]c2ccc(Cl)cc12.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)C(O)=CC(=O)c1cn(S(=O)(=O)c2ccccc2)c2ccc(Cl)cc12,,C1CCOC1,,CN(C)C=O,[H-].[Na+],val
+US20110135650A1,CC(C)(C)OC(=O)Nc1ncnc2cc([N+](=O)[O-])ccc12>>CC(C)(C)OC(=O)Nc1ncnc2cc(N)ccc12,[Pd],C1CCOC1,CO,,,val
+US20160200715A1,COC(=O)[C@@]12CC(F)(F)[C@@H](C)[C@H](/C=C/c3ccc(Br)cn3)[C@@H]1[C@@H](C)OC2=O.NN>>C[C@H]1[C@H](/C=C/c2ccc(Br)cn2)[C@@H]2[C@@H](C)OC(=O)[C@]2(C(=O)NN)CC1(F)F,,CCO,CCOC(C)=O,,,val
+US20120035364A1,OC1C2=C(C3C=CC2CC3)C(O)c2cc3sc(=S)sc3cc21>>S=c1sc2cc3cc4c(cc3cc2s1)C1C=CC4CC1,,c1ccncc1,,O,,val
+US06002008,N#Cc1cnc2ccc(N)cc2c1Nc1cccc(Br)c1.O=C(Cl)CCl>>N#Cc1cnc2ccc(NC(=O)CCl)cc2c1Nc1cccc(Br)c1,,C1CCOC1,,CCN(CC)CC,,val
+US20140249146A1,CCN(C(C)C)C(C)C.CCOC(C)=O.CS(=O)(=O)Cl.ClCCl.O=C([O-])O.O=C1NCCn2cc(-c3cccc(OC(F)(F)F)c3)cc21>>CS(=O)(=O)NCC[C@H]1CNC(=O)c2cc(-c3cccc(OC(F)(F)F)c3)c(-c3ccccc3)n21,,CCOC(C)=O,ClCCl,Cl,,val
+US06545033B1,CC(=O)C1CCCCC1=O.NNc1c(Cl)cc(C(F)(F)F)cc1Cl>>Cc1c2c(nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl)CCCC2,,CCO,,,,val
+US04073770,CC1=CC(C)(C)Nc2cc(C)ccc21>>CC1CCC2C(C)CC(C)(C)NC2C1,[Rh],,,[H][H],,val
+US05283248,CC(C)(C)OC(=O)N1CCN(c2cc3c(cc2F)n2c(=O)n(OCc4ccccc4)c(=O)cc2n3C2CC2)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc3c(cc2F)n2c(=O)n(O)c(=O)cc2n3C2CC2)CC1,[Pd],CCO,,,,val
+US20100210694A1,CC(=O)Oc1ccccc1C(=O)OCCl.O=C(O)CCCC(CO[N+](=O)[O-])O[N+](=O)[O-]>>CC(=O)Oc1ccccc1C(=O)OCOC(=O)CCCC(CO[N+](=O)[O-])O[N+](=O)[O-],,CN(C)C=O,O,CCN(CC)CC,,val
+US20100260709A1,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@]2(CN1C(=O)[C@@H](N)C(C)(C)C)C(C)(C)C21CCC1)C(=O)NS(=O)(=O)N1CCCC1.CC(C)(C)OC(=O)N[C@H](C(=O)O)C1(C)CCCCC1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@]2(CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C1(C)CCCCC1)C(C)(C)C)C(C)(C)C21CCC1)C(=O)NS(=O)(=O)N1CCCC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20120202777A1,CC(CCc1ccc(-c2ccccc2O)cc1)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>CC(CCc1ccc(-c2ccccc2O)cc1)(C(=O)NO)S(C)(=O)=O,,ClCCl,,CO,Cl,val
+US05219862,CCCN1C[C@H](CC#N)C[C@@H]2c3cccc4[nH]c(COC)c(c34)C[C@H]21>>CCCN1C[C@H](CC#N)C[C@@H]2c3cccc4[nH]c(C)c(c34)C[C@H]21,,ClC(Cl)Cl,,,,val
+US20100210647A1,C1COCCN1.CS(=O)(=O)Cc1cc(NC2CCCC2)c2[nH]c(C3=N[C@H](CCI)CS3)cc2c1>>CS(=O)(=O)Cc1cc(NC2CCCC2)c2[nH]c(C3=N[C@H](CCN4CCOCC4)CS3)cc2c1,,CN(C)C=O,,,,val
+US20090286775A1,O=C1c2ccc(O)cc2CCN1c1ccccc1Cl.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1c2ccc(OS(=O)(=O)C(F)(F)F)cc2CCN1c1ccccc1Cl,,ClCCl,,c1ccncc1,,val
+US04087522,COP(=O)(CC(=O)O)OC.NC1CCCCC1>>O=C(CP(=O)(O)O)NC1CCCCC1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,val
+US20080096938A1,CCCCCCCCOc1ccc(C(=O)NNC(=O)[C@]2(C)COC(C)(C)N2C(=O)OC(C)(C)C)cc1C(F)(F)F.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCCCCCCCOc1ccc(-c2nnc([C@@]3(C)COC(C)(C)N3C(=O)OC(C)(C)C)s2)cc1C(F)(F)F,,Cc1ccccc1,,,,val
+US20020019371A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)Cc1cccc(N)c1>>CCOC(=O)Cc1cccc(NC(=O)OC(C)(C)C)c1,,C1CCOC1,,,,val
+US20090054402A1,Cc1ccccc1-c1cccc2c(CCC=Cc3cccc4ccccc34)c(C(=O)O)[nH]c12>>Cc1ccccc1-c1cccc2c(CCCCc3cccc4ccccc34)c(C(=O)O)[nH]c12,[Pd],CCO,CCOC(C)=O,,,val
+US20060276508A1,CCOC(=O)c1ccc(I)c(OCC)c1.CCOc1cc(C=O)ccc1I>>CCOc1cc(C=O)ccc1C1CC1,O=[Mn]=O,,,CC(C)C[AlH]CC(C)C,,val
+US05891909,COc1cc(CCCC2OCCCO2)cc(OS(=O)(=O)c2ccccc2Cl)c1>>COc1cc(CCCC=O)cc(OS(=O)(=O)c2ccccc2Cl)c1,,C1CCOC1,O,Cl,,val
+US20090197863A1,COC(=O)c1cccc2nc(-c3cccc(C(=O)N4CCN(C(=O)C5CC5)CC4)c3)oc12.[NH4+]>>NC(=O)c1cccc2nc(-c3cccc(C(=O)N4CCN(C(=O)C5CC5)CC4)c3)oc12,,CO,,,,val
+US20090137595A1,COC(=O)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>O=C(O)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1,,C1CCOC1,,Cl,[Na+].[OH-],val
+US20010027196A1,CSc1nc(N)cc(-c2ccco2)c1C#N.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CS(=O)c1nc(N)cc(-c2ccco2)c1C#N,,ClCCl,,,,val
+US20150284343A1,FC(F)(F)Oc1cccc(Oc2nn(-c3ccc(C(F)(F)F)cc3)nc2CBr)c1>>Cc1nn(-c2ccc(C(F)(F)F)cc2)nc1Oc1cccc(OC(F)(F)F)c1,[Pd],,,,,val
+US20160221972A1,COC(=O)c1ccc2c(c1)O[C@H](C)CNC2.COc1ccc(N=C=O)cc1>>COC(=O)c1ccc2c(c1)O[C@H](C)CN(C(=O)Nc1ccc(OC)cc1)C2,,ClCCl,,CCN(CC)CC,,val
+US04497953,COC(=O)[C@@H]1CC(N2CCCCC2)CN1>>COC(=O)[C@@H]1C[C@H](N2CCCCC2)CN1,[Pd],CO,O,[H][H],,val
+US20140213578A1,Clc1ccc2c(c1)CCc1ccccc1N2.O=C(Cl)CCl>>O=C(CCl)N1c2ccccc2CCc2cc(Cl)ccc21,,Cc1ccccc1,,,,val
+US20120172391A1,C=Cc1cnc(C=C)c(C(=O)OC)c1.COc1ccc(CN)cc1>>C=Cc1cnc2c(c1)C(=O)N(Cc1ccc(OC)cc1)CC2,,CC(=O)N(C)C,,,,val
+US20120258952A1,CCc1nn(Cc2cnn(CCO[Si](C)(C)C(C)(C)C)c2)c2cccc(NC(=O)c3cnc4ccccn34)c12>>CCc1nn(Cc2cnn(CCO)c2)c2cccc(NC(=O)c3cnc4ccccn34)c12,Cl,CO,,,,val
+US20120283297A1,CC(C)Oc1ncc(-c2nc(-c3cc4cn[nH]c4cc3Cl)no2)cc1Cl.CCOC(=O)CCCBr>>CCOC(=O)CCCn1ncc2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)c(Cl)cc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20030055076A1,COC(=O)[C@H](Cc1ccc(OCCN2c3ccccc3Oc3ccccc32)cc1)Nc1ccccc1C(=O)c1ccccc1>>O=C(c1ccccc1)c1ccccc1N[C@@H](Cc1ccc(OCCN2c3ccccc3Oc3ccccc32)cc1)C(=O)O,,CCO,,[Na+].[OH-],,val
+US20120101080A1,O=C(Cl)CCCc1ccccc1.c1ccc(CC2CNC2)cc1>>O=C(CCCc1ccccc1)N1CC(Cc2ccccc2)C1,,ClCCl,,CCN(CC)CC,,val
+US05043482,COc1ccc(O)c2c1C(C)(C)CCC2(C)C.O=C(Cl)c1ccccc1>>COc1cc(Cc2ccccc2)c(O)c2c1C(C)(C)CCC2(C)C,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,val
+US20140155391A1,COC(=O)c1ccc(N)c(OCC2CC2)c1.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)Nc1ccc(C(=O)OC)cc1OCC1CC1,,ClCCl,,c1ccncc1,,val
+US04769503,ClCl.Clc1ccc(C(Cl)(Cl)Cl)cc1>>Clc1ccc(C(Cl)(Cl)Cl)cc1Cl,,Cl,,,,val
+US20050070547A1,C[O-].FC(F)(F)c1cccnc1-c1cnc2c(Cl)cc(Cl)nc2c1>>COc1cc(Cl)c2ncc(-c3ncccc3C(F)(F)F)cc2n1,,C1CCOC1,,O,,val
+US05936123,CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)C3CC4CC(C3)CC2C4)nn1-c1ccc(C(=O)N(C)CCCN(C)C)cc1C(C)C>>CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)C3CC4CC(C3)CC2C4)nn1-c1ccc(C(=O)N(C)CCCN(C)C)cc1C(C)C,,CCO,,ClCCl,,val
+US05403675,O=C(Cl)c1cc(Cl)ccc1Cl.c1ccc(Oc2ccccc2)cc1>>O=C(c1ccc(Oc2ccccc2)cc1)c1cc(Cl)ccc1Cl,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],val
+US05597848,COC(=O)CCCc1ccc(C(O)Cc2ccccc2)cc1.O=S(Cl)Cl>>COC(=O)CCCc1ccc(C(Cl)Cc2ccccc2)cc1,,c1ccccc1,,,,val
+US20040133011A1,CC1(CCCC23CCC(c4nnc(-c5ccccc5C(F)(F)F)o4)(CC2)CC3)OCCO1>>CC(=O)CCCC12CCC(c3nnc(-c4ccccc4C(F)(F)F)o3)(CC1)CC2,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,val
+US20030220368A1,COc1ncccc1CCl.[C-]#N>>COc1ncccc1CC#N,,O,,CN(C)C=O,,val
+US20090181965A1,BrBr.O=C1CCCCC1c1ccccc1Cl>>O=C1C(Br)CCCC1c1ccccc1Cl,,ClC(Cl)Cl,,,,val
+US20080293712A1,O=P(Cl)(Cl)Cl.Oc1nccc2c1cnc1ccc(Br)cc12>>Clc1nccc2c1cnc1ccc(Br)cc12,,CN(C)C=O,,,,val
+US20130035446A1,O=C(/C=C/c1ccc(C(F)(F)Oc2ccc(OCCCC(F)(F)F)cc2)cc1)OCCc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>Nc1ccc(CCOC(=O)/C=C/c2ccc(C(F)(F)Oc3ccc(OCCCC(F)(F)F)cc3)cc2)c(N)c1,[Zn],CN(C)C=O,O,,,val
+US20050154201A1,Cc1cccnc1[C@@H]1CCC[C@H](c2ncccc2C)N1.FC(F)Oc1ccccc1CBr>>Cc1cccnc1[C@@H]1CCC[C@H](c2ncccc2C)N1Cc1ccccc1OC(F)F,,CC#N,,CCN(C(C)C)C(C)C,,val
+US20090163488A1,CCc1nc(C(=O)O)c(C(F)(F)F)o1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>CCc1nc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)c(C(F)(F)F)o1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,val
+US20070244125A1,CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCS(=O)(=O)CC4)cc3c2)CC1.N#CCBr>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)N2CCS(=O)(=O)CC2)n3CC#N)CC1,,CN(C)C=O,,[H-].[Na+],,val
+US20060063828A1,BrBr.COc1cccc(OC)c1C=O>>COc1ccc(Br)c(OC)c1C=O,,ClCCl,,,,val
+US20160176850A1,Clc1cc(Cl)nc(Cl)n1.c1cnc2[nH]nc(C3CCNCC3)c2c1>>Clc1cc(N2CCC(c3n[nH]c4ncccc34)CC2)nc(Cl)n1,,CO,,Cl,,val
+US04366315,CC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3ccccc3)[C@H]2S(=O)C1.C[Si](C)(C)NC(=O)N[Si](C)(C)C.O=C1c2ccccc2C(=O)N1Br>>C[Si](C)(C)OC(=O)C1=C(CBr)CS(=O)[C@@H]2C(NC(=O)Cc3ccccc3)C(=O)N12,,ClCCCl,,CS(=O)(=O)O,,val
+US20030109539A1,CC(=O)O.CC(=O)O[BH-](OC(C)=O)OC(C)=O.O=C1NCN(c2ccccc2)C12CCNCC2.O=Cc1cccnc1Br.[Na+]>>O=C([O-])O.O=C1NCN(c2ccccc2)C12CCN(Cc1cccnc1Br)CC2.[Na+],,C1CCOC1,O,,,val
+US20120010183A1,CC(=O)OO.CC(C)COc1ncc(B(O)O)cc1Cl>>CC(C)COc1ncc(O)cc1Cl,,CC(=O)O,O,,,val
+US04310526,CCCc1c(/C=C/c2ccccc2C)nc2ccc(C(=O)O)cn2c1=O.CCN(CC)CCCl>>CCCc1c(/C=C/c2ccccc2C)nc2ccc(C(=O)OCCN(CC)CC)cn2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US04377580,CCOC=C1C(=O)OC(C)(C)OC1=O.Nc1ncnc2ccccc12>>CC1(C)OC(=O)C(=CNc2ncnc3ccccc23)C(=O)O1,,CN(C)C=O,,,,val
+US20100087427A1,CC(C)c1cccc(C[C@H]2CN(Cc3ccccc3)C[C@@H]2C#N)c1>>CC(C)c1cccc(C[C@H]2CNC[C@@H]2C#N)c1,,ClCCCl,,CC(Cl)OC(=O)Cl,,val
+US05286902,C=C(C)c1ccc2cc(OC)ccc2c1.O=[Se]=O>>C=C(CO)c1ccc2cc(OC)ccc2c1,,ClCCl,,,,val
+US20080214545A1,CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)n(-c2ccc(N)cc2)n1.CC1(C)CC(=O)OC1=O>>CC(C)(CC(=O)Nc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccncc3)cc2)cc1)C(=O)O,,C1CCOC1,CCOCC,,,val
+US07659304B2,C=CCBr.COC(=O)[C@H](Cc1c(Br)[nH]c2cc(Br)c(OC)c(Br)c12)NC(C)=O>>C=CCn1c(Br)c(C[C@H](NC(C)=O)C(=O)OC)c2c(Br)c(OC)c(Br)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],val
+US20100130492A1,CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)C[C@@H]1C.CS(=O)(=O)O>>CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)C[C@@H]1C.CS(=O)(=O)O,,CO,ClCCl,,,val
+US20130210844A1,CC(C)(C)C(=O)Cl.COC(=O)c1cc(CN)c(F)cc1Cl>>COC(=O)c1cc(CNC(=O)C(C)(C)C)c(F)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US20050054645A1,CC(C)(C)OC(=O)NCCN.O=Cc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)NCCNCc1ccc(Cl)c(Cl)c1,,ClC(Cl)Cl,,CC(=O)O,O=C([O-])O.[Na+],val
+US20120059015A1,NO.O=CC#Cc1ccccc1>>ON=CC#Cc1ccccc1,,O,,CCO,Cl,val
+US20110021537A1,CCOC(=O)N1CCN(C(=O)OCc2ccccc2)[C@H](C)C1>>CCOC(=O)N1CCN[C@H](C)C1,[Pd],CCOC(C)=O,,,,val
+US20150119380A1,Cc1cn2cc(-c3cc4ccc(C5(F)CCN(C(=O)OCc6ccccc6)CC5)cc4oc3=O)nc2c(C)n1>>Cc1cn2cc(-c3cc4ccc(C5(F)CCNCC5)cc4oc3=O)nc2c(C)n1,[Pd],CO,ClCCl,,,val
+US20120245152A1,C[C@H](Oc1ncc(F)cc1NC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)OC(C)(C)C>>C[C@@H]1Oc2ncc(F)cc2N(C2CCNCC2)C1=O,,O=C(O)C(F)(F)F,,,,val
+US20020091264A1,CCOC(=O)C[C@@H]1Cc2ccc(OCCCNc3cc(OCC)ccn3)cc2Cc2ccccc21>>CCOc1ccnc(NCCCOc2ccc3c(c2)Cc2ccccc2[C@H](CC(=O)O)C3)c1,,CCO,,Cl,[Na+].[OH-],val
+US20100234351A1,CC(C)(C)OC(=O)NO.COCCBr>>COCCONC(=O)OC(C)(C)C,,CN(C)C=O,,O,[H-].[Na+],val
+US20140005164A1,CI.COc1ccc2[nH]c(=O)n(C[C@@H]3CC[C@@H](C(=O)N4CCN(c5ncccn5)CC4)CC3)c2c1>>COc1ccc2c(c1)n(C[C@@H]1CC[C@@H](C(=O)N3CCN(c4ncccn4)CC3)CC1)c(=O)n2C,,CN(C)C=O,,[H-].[Na+],,val
+US20140221311A1,C[C@H](N)C(F)(F)F.Nc1ncc(-c2ccc(-c3ccccc3C(=O)O)cc2F)cn1>>C[C@H](NC(=O)c1ccccc1-c1ccc(-c2cnc(N)nc2)c(F)c1)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20040009983A1,Cc1ccc(S(=O)(=O)n2c(-c3cn(C)c4ccc(C5=CCN(C(=O)OCc6ccccc6)CC5)cc34)cc3cccnc32)cc1>>Cc1ccc(S(=O)(=O)n2c(-c3cn(C)c4ccc(-c5ccncc5)cc34)cc3cccnc32)cc1,[Pd],CCO,,[H][H],,val
+US04855086,COc1cccc(CN)c1.O=C(O)/C=C/CCC#Cc1ccccc1>>COc1cccc(CNC(=O)/C=C/CCC#Cc2ccccc2)c1,,CCOCC,,CCN(CC)CC,,val
+US20100158818A1,CC(C)(CC(=O)O)NC(=O)OCc1ccccc1.OCCN1CCCCC1>>CC(C)(CC(=O)OCCN1CCCCC1)NC(=O)OCc1ccccc1,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,val
+US20070275968A1,COC(OC)N(C)C.NN.O=C(Cc1ccc(F)c(Br)c1)c1ccccn1>>Fc1ccc(-c2c[nH]nc2-c2ccccn2)cc1Br,,C1CCOC1,CCO,O,,val
+US20020173518A1,CC(C)(C)OC(=O)n1ncc2ccc(NC(=O)c3ccccc3N)cc21.CC(C)(C)c1ccc2c(c1)C(=O)OC2=O>>CC(C)(C)c1ccc2c(c1)C(=O)N(c1ccccc1C(=O)Nc1ccc3cn[nH]c3c1)C2=O,,C1CCOC1,CCOCC,,,val
+US20110212918A1,CC(=O)Nc1cnc(S(=O)(=O)Cl)c(Br)c1.Nc1ccc2c(c1)B(O)OC2>>CC(=O)Nc1cnc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Br)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20080015191A1,COc1cc(Nc2cncc(Oc3ccc(N)cc3)n2)cc(OC)c1OC.O=C(Cl)c1ccc(Cl)cc1>>COc1cc(Nc2cncc(-c3ccc(C(=O)c4ccc(Cl)cc4)cc3N)n2)cc(OC)c1OC,,CCOC(C)=O,,,,val
+US20090298807A1,COc1ccc(CC(=O)O)c(F)c1F>>O=C(O)Cc1ccc(O)c(F)c1F,,ClCCl,,BrB(Br)Br,,val
+US20070004730A1,CNC(=N)N.O=C(C(=O)c1ccncc1)c1ccccc1>>CN1C(=O)C(c2ccccc2)(c2ccncc2)N=C1N,,CCO,O,Cl,O=C([O-])[O-].[Na+].[Na+],val
+US05246948,O=C(NCCCSc1ccncc1)c1ccccc1CO>>O=C1c2ccccc2CN1CCCSc1ccncc1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,val
+US20120270875A1,CCOC(=O)c1c(C)nc(NC/C=C/B2OC(C)(C)C(C)(C)O2)nc1C.Cc1ccc(Br)cc1O>>CCOC(=O)c1c(C)nc(NC/C=C/c2ccc(C)c(O)c2)nc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],val
+US20040002492A1,CC(=O)c1cccc2c1Sc1ccccc1S2.S=C=S>>O=C(CC(=S)S)c1cccc2c1Sc1ccccc1S2,,C1CCOC1,,CC(C)(C)[O-].[K+],,val
+US20120245144A1,C=C(OCC)c1cc2c(cc1OC)OCCn1cc(-c3nc(C)nn3C(C)C)nc1-2>>COc1cc2c(cc1C(C)=O)-c1nc(-c3nc(C)nn3C(C)C)cn1CCO2,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,val
+US20130090323A1,COC[C@H]1CCCN1.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>COC[C@H]1CCCN1c1nc2cc(F)cc(F)c2c(Cl)c1C,,CC#N,,CCN(CC)CC,,val
+US05342846,COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cc1cnnn1C1CCNC1>>COc1c(N2CCC(n3nncc3C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12,,CC#N,,C1CCC2=NCCCN2CC1,Cl,val
+US20060135556A1,Cc1ccc2c(C)ccc([N+](=O)[O-])c2n1>>Cc1ccc2c(C)ccc(N)c2n1,[Ni],CCO,,,,val
+US20150336949A1,Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c[nH]c2ncc(-c3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3)cc12>>Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c[nH]c2ncc(-c3ccc(C4CCNCC4)cc3)cc12,,ClCCl,O=C(O)C(F)(F)F,,,val
+US04933355,C=CCNc1nc(C(=O)OCC)cs1>>C=CCNc1nc(CO)cs1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,val
+US20120184543A1,CO[C@H](CN1CCN(CC2CC2)CC1)CN(Cc1ccccc1)Cc1ccccc1>>CO[C@@H](CN)CN1CCN(CC2CC2)CC1,[Pd],CO,,[H][H],,val
+US20060111336A1,C[C@@H](c1ccc(F)cc1)[C@H](N=[N+]=[N-])C(=O)N1C(=O)OC[C@@H]1c1ccccc1.OO>>C[C@@H](c1ccc(F)cc1)[C@H](N=[N+]=[N-])C(=O)O,,C1CCOC1,,O,[Li+].[OH-],val
+US04070539,CCC1Cc2cc(O)c(Cl)c(Cl)c2C1=O.CCOC(=O)CBr>>CCOC(=O)COc1cc2c(c(Cl)c1Cl)C(=O)C(CC)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20080242655A1,CCOC(=O)c1c(Nc2ccc([Si](C)(C)C)cc2F)c2cncc(Cl)c2n1C.ClI>>CCOC(=O)c1c(Nc2ccc(I)cc2F)c2cncc(Cl)c2n1C,,ClCCl,,,,val
+US20080279800A1,CC(O)C(C)C(C)C(C)C(C)(C)C>>CC(=O)C(C)C(C)C(C)C(C)(C)C,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,val
+US20150057316A1,N#Cc1cccc(S(=O)(=O)Cl)c1.O.c1ccncc1>>N#Cc1cccc(S(=O)(=O)[O-])c1.c1cc[nH+]cc1,,C1CCOC1,,,,val
+US20030195230A1,Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.O=C(O)c1cccnc1Nc1ccc2cn[nH]c2c1>>O=C(Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1cccnc1Nc1ccc2cn[nH]c2c1,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,val
+US20150175602A1,CC1Cc2nc(NCC(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2CN1.O=C(O)C(F)(F)F.O=C(O)C1CC1>>CC1Cc2nc(NCC(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2CN1C(=O)C1CC1.O=C(O)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20120053166A1,COc1ncc(-c2cc(-c3nnc(CN4C[C@H](C)O[C@H](C)C4)o3)c3cnn(S(=O)(=O)c4ccccc4)c3c2)cc1N.O=S(=O)(Cl)c1ccc(F)cc1F>>COc1ncc(-c2cc(-c3nnc(CN4C[C@H](C)O[C@H](C)C4)o3)c3cnn(S(=O)(=O)c4ccccc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F,,c1ccncc1,,O,,val
+US20060211724A1,CC(C)(C)C(=O)O.O=C1c2c(c(O)c3nccnc3c2O)C(=O)N1Cc1ccc(Cl)c(Cl)c1>>CC(C)(C)C(=O)Oc1c2c(c(O)c3nccnc13)C(=O)N(Cc1ccc(Cl)c(Cl)c1)C2=O,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,val
+US20090023763A1,Nc1nc(-c2ccco2)c(-c2ccncc2)cc1[N+](=O)[O-]>>Nc1cc(-c2ccncc2)c(-c2ccco2)nc1N,[Pd],CCO,,,,val
+US20090264445A1,COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(O)O.O=CC1CC2CCC1C2>>COC(=O)C(=CC1CC2CCC1C2)NC(=O)OCc1ccccc1,,ClCCl,,C1CCC2=NCCCN2CC1,,val
+US20140274696A1,COC(=O)c1nc(-c2ccc([Si](C)(C)C)c(F)c2F)nc(N)c1OC.ClI>>COC(=O)c1nc(-c2ccc(I)c(F)c2F)nc(N)c1OC,,CCOC(C)=O,ClCCCl,,,val
+US20060122184A1,C[C@@H](C[C@H](NC(=O)c1ccc(-c2ccccc2Cl)cc1)C(=O)NC1(C#N)CCSCC1)c1ccccc1.O=S([O-])OO>>C[C@@H](C[C@H](NC(=O)c1ccc(-c2ccccc2Cl)cc1)C(=O)NC1(C#N)CCS(=O)(=O)CC1)c1ccccc1,,CO,,O,,val
+US20030004157A1,C1CSCCN1.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(N2CCSCC2)nc1,,C1CCOC1,,,,val
+US20060148817A1,C=CCBr.CC(=O)Nc1cc(OCc2ccccc2)c(C(C)=O)cc1Br>>C=CCN(C(C)=O)c1cc(OCc2ccccc2)c(C(C)=O)cc1Br,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,val
+US05156918,C=CCN(CC=C)c1ccccc1C=O.C=CCNCC=C.O=Cc1ccc(F)cc1>>C=CCN(CC=C)c1ccc[n+]([O-])c1C=Cc1ccccc1,,CO,CS(C)=O,O=C([O-])[O-].[K+].[K+],,val
+US20130065876A1,CC(C)(C)OC(=O)N1OC1c1ccc(C#N)cc1.CC(C)(C)[Si](C)(C)OC1CNC1>>CC(C)(C)OC(=O)NN1CC(O[Si](C)(C)C(C)(C)C)C1,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US05484462,C1COCCN1.C=CC#N>>NCCCN1CCOCC1,CCN(CC)CC,,,,,val
+US20140235647A1,CC(=O)OO.N#Cc1nccc(-c2cncnc2)c1F>>N#Cc1nccc(-c2cncnc2O)c1F,,CC(C)=O,ClCCl,O=S(=O)(O)O,[Na+].[OH-],val
+US20150133428A1,CCOC(=O)C1(C)CC2(C1)CC2(F)F>>CC1(C(=O)O)CC2(C1)CC2(F)F,,C1CCOC1,O,[Na+].[OH-],,val
+US20160212997A1,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1SC1CCNC1=O.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1S(=O)C1CCNC1=O,,ClCCl,,O,,val
+US05240938,C=CCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)ccc1O[Si](C)(C)C(C)(C)C>>C=CCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)ccc1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,val
+US05621104,CC12CCC(=O)C=C1CCc1ccccc12.OCCO>>CC12CC3OCCOC3CC1=CCc1ccccc12,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,val
+US20100130495A1,Cc1nccn1-c1ccc(Nc2nc(O)c3c(n2)CCN(C(=O)OC(C)(C)C)C3)cc1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1nccn1-c1ccc(Nc2nc3c(c(OS(=O)(=O)C(F)(F)F)n2)CN(C(=O)OC(C)(C)C)CC3)cc1,CN(C)c1ccncc1,ClCCl,,C1CCC2=NCCCN2CC1,,val
+US20060106013A1,O=[N+]([O-])c1ccc(C2CCN(CC3CC3)CC2)cc1>>Nc1ccc(C2CCN(CC3CC3)CC2)cc1,[Pd],C1CCOC1,CCO,[H][H],,val
+US20020110650A1,Nc1ccc2c(c1)sc1cc(Br)ccc12.O=N[O-]>>Oc1ccc2c(c1)sc1cc(Br)ccc12,,O,,O=S(=O)(O)O,,val
+US20020035110A1,CCOC(=O)c1cc2c(Br)cccc2[nH]1.N#CCCl>>CCOC(=O)c1cc2c(Br)cccc2n1CC#N,,CN(C)C=O,,[H-].[Na+],,val
+US04596816,CCOC(C)=O.ICCc1ocnc1-c1ccccc1>>O=C(O)CCc1ocnc1-c1ccccc1,,CS(C)=O,,[Na],,val
+US05326773,CC(C)(C)OC(=O)N[C@H]1CCC(C)(C)OC1=O.Cl>>CC1(C)CC[C@H](N)C(=O)O1.Cl,,CCOC(C)=O,,,,val
+US20140024650A1,CCOC(=O)C1COCCC1NCc1ccccc1>>CCOC(=O)C1COCCC1N,,CCO,,,,val
+US20110144084A1,O=C(O)c1cncc(Cl)n1.O=S(Cl)Cl>>O=C(Cl)c1cncc(Cl)n1,,CC#N,,,,val
+US20160030395A1,Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCN(C(=O)OC(C)(C)C)CC1)C(=O)N2>>Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCNCC1)C(=O)N2,,ClCCl,O,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],val
+US20080027096A1,BrCc1cccc(Br)c1.COC(=O)C(O)Cc1cc(Br)c(O)c(Br)c1>>O=C(O)C(O)Cc1cc(Br)c(OCc2cccc(Br)c2)c(Br)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20040077622A1,OCc1cc2c(o1)CCC2>>O=Cc1cc2c(o1)CCC2,O=[Mn]=O,ClC(Cl)Cl,,,,val
+US20080064676A1,CCOC(=O)CSCC1(c2ccc(Cl)cc2)OCC(C)(C)CO1>>CC1(C)COC(CSCC(=O)O)(c2ccc(Cl)cc2)OC1,,C1CCOC1,O,[Li+].[OH-],,val
+US20140093505A1,CCOC(=O)c1cnc2ccc(Cl)nc2c1Cl.Nc1cccc(C(F)(F)F)c1>>CCOC(=O)c1cnc2ccc(Cl)nc2c1Nc1cccc(C(F)(F)F)c1,,CC(C)(C)O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],val
+US20080070946A1,C=CCC(OC(=O)[O-])c1nc2cc(N)ccc2s1.CN(C)c1ccc(C(=O)Cl)cc1>>CN(C)c1ccc(C(=O)Nc2ccc3sc(CO)nc3c2)cc1,CN(C)c1ccncc1,CO,ClCCl,CCN(CC)CC,[Na+].[OH-],val
+US20080318930A1,CCS(=O)(=O)CCCC12CCC(C(=O)O)(CC1)CC2.NC1C2CC3CC(C2)CC1C3>>CCS(=O)(=O)CCCC12CCC(C(=O)NC3C4CC5CC(C4)CC3C5)(CC1)CC2,,CCN(CC)CC,ClCCl,CN(C)C=O,O=C(Cl)C(=O)Cl,val
+US20130059849A1,CCOC(=O)c1cc(-c2ccccc2)nc2c1cnn2C(C)C.O=[N+]([O-])O>>CCOC(=O)c1cc(-c2ccccc2[N+](=O)[O-])nc2c1cnn2C(C)C,,O,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],val
+US20090069288A1,CC(=O)c1ccc(O)cc1.CC1(C)OCC(CO)O1>>CC(=O)c1ccc(OCC2COC(C)(C)O2)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,val
+US20120101083A1,Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)CBr)CC2.NCCO>>Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)CNCCO)CC2,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20150175530A1,CC(C)(C)[Si](C)(C)OC/C=C\CO[Si](C)(C)C(C)(C)C.O=[O+][O-]>>CC(C)(C)[Si](C)(C)OCC=O,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,val
+US20020042427A1,CNS(=O)(=O)c1ccc2c(c1)CC(=O)N2.O=Cc1[nH]cc2c1CCNC2=O>>CNS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]cc3c1CCNC3=O)C(=O)N2,,CCO,,C1CCNCC1,,val
+US20150239895A1,CC(C)(C)OC(=O)Cn1nc(C(N)=O)c2cc(Cl)ncc21.OB(O)c1cncnc1>>NC(=O)c1nn(CC(=O)O)c2cnc(-c3cncnc3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],val
+US20090227640A1,FC(F)(F)c1ccc(-c2ccc(CCl)cc2)cc1.OCc1ccccc1O>>OCc1ccccc1OCc1ccc(-c2ccc(C(F)(F)F)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US03991071,CCCNCc1ccc(Cl)cc1.O=C(Cl)Cl>>CCCN(Cc1ccc(Cl)cc1)C(=O)Cl,,CCOC(C)=O,,,,val
+US20100234367A1,O=C1C=CCC1.c1cn[nH]c1>>O=C1CCC(n2cccn2)C1,,ClCCl,,O,,val
+US20160257951A1,CCCCCCCCCCC(=O)CCCCCCC/C=C\C[C@@H](CCCCCC)O[Si](C)(C)C(C)(C)C>>CCCCCCCCCCC(O)CCCCCCC/C=C\C[C@@H](CCCCCC)O[Si](C)(C)C(C)(C)C,,C1CCOC1,CO,[BH4-].[Na+],,val
+US05677302,CCCCn1sc2nc3ccccc3n2c1=O.N#CBr>>Brc1nsc2nc3ccccc3n12,,ClCCl,,,,val
+US20100239576A1,CS(=O)(=O)Cl.O=C(OC1(CCO)CC1)c1ccccc1>>CS(=O)(=O)OCCC1(OC(=O)c2ccccc2)CC1,,ClCCl,,,,val
+US20120142717A1,C=Cc1ccc(Oc2cnc(C(F)(F)F)nc2)c(F)c1.OO>>OCCc1ccc(Oc2cnc(C(F)(F)F)nc2)c(F)c1,,C1CCOC1,,B1C2CCCC1CCC2,[Na+].[OH-],val
+US20050137212A1,COc1ccc(C=O)cc1C.C[N+](=O)[O-]>>COc1ccc(/C=C/[N+](=O)[O-])cc1C,,CO,O,Cl,[Na+].[OH-],val
+US06437165B1,CCCCCCCCc1ccc(CCC(C)(CCP(=O)(OCC)OCC)NC(=O)OCc2ccccc2)cc1>>CCCCCCCCc1ccc(CCC(C)(N)CCP(=O)(O)O)cc1,,ClCCl,,CO,,val
+US20070099990A1,CC(C)c1ccc(C(O)C(=O)O)cc1.Oc1ccc(Br)cc1>>CC(C)c1ccc(C2C(=O)Oc3ccc(Br)cc32)cc1,,CO,,,,val
+US20100317568A1,CC(C)(C)c1ccc(N2C(C(=O)O)CCC2C(=O)O)cc1>>CC(C)(C)c1ccc(N2[C@@H](C(=O)O)CC[C@@H]2C(=O)O)cc1,,O,,CC#N,,val
+US20050054658A1,CS(=O)(=O)Cl.OC1CCC(OCCc2ccccc2)C(F)C1>>CS(=O)(=O)OC1CCC(OCCc2ccccc2)C(F)C1,,CCCCCC,CCOC(C)=O,CCN(C(C)C)C(C)C,ClCCl,val
+US20120028919A1,CSc1ncc2c(O)ccn2n1.C[Si](C)(C)CCOCCl>>CSc1ncc2c(OCOCC[Si](C)(C)C)ccn2n1,,CN(C)C=O,CN(C)C=O,[H-].[Na+],,val
+US20160083400A1,O=c1[nH]c(NC(CCO)c2cccc(Cl)c2)nc2c(C3CCCC3)onc12>>O=C1c2noc(C3CCCC3)c2NC2=NC(c3cccc(Cl)c3)CCN12,,ClCCl,,CS(=O)(=O)Cl,,val
+US05545636,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1ccc2c(c1)ccn2C1CCNCC1>>O=C(N1CCC(n2ccc3ccccc32)CC1)C(F)(F)F,,c1ccncc1,,,,val
+US20140018313A1,COC[C@H]1C[C@@H](c2ncc(-c3cc4c5c(c3)OCc3cc(-c6cnc([C@@H]7C[C@H](C)CN7C(=O)[C@H](NC(=O)OC)c7ccccc7)[nH]6)cc(c3-5)OC4)[nH]2)N(C(=O)OC(C)(C)C)C1>>COC[C@@H]1CN[C@H](c2ncc(-c3cc4c5c(c3)OCc3cc(-c6cnc([C@@H]7C[C@H](C)CN7C(=O)[C@H](NC(=O)OC)c7ccccc7)[nH]6)cc(c3-5)OC4)[nH]2)C1,,CCO,,Cl,,val
+US20040229927A1,CO.NC(=O)c1ccc(-c2cnc(-c3ccc([N+](=O)[O-])cc3)[nH]2)cc1>>COC(=O)c1ccc(-c2cnc(-c3ccc([N+](=O)[O-])cc3)[nH]2)cc1,,CO,ClCCl,Cl,,val
+US20100305096A1,CC(C)(C)OC(=O)N1CC(NC(=O)CCCCl)C1>>CC(C)(C)OC(=O)N1CC(N2CCCC2=O)C1,,CN(C)C=O,,[H-].[Na+],,val
+US05616620,CC(=O)OC(C)=O.NC(=N[N+](=O)[O-])NCCC[C@@H](N)C(=O)NCc1ccc(O)cc1>>CC(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)NCc1ccc(O)cc1,,CC(=O)O,,,,val
+US20140194431A1,O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4ccc(Cl)cc4)CCCC3)n2CCN1C1CC1>>O=C1c2c(O)c(=O)nc(CC3(c4ccc(Cl)cc4)CCCC3)n2CCN1C1CC1,,CC(=O)O,,O=S(=O)(O)O,,val
+US20050192347A1,CC(C)(CO)CCCN.O=C=NCCc1ccccc1>>CC(C)(CO)CCCNC(=O)NCCc1ccccc1,,ClCCl,,,,val
+US20100305093A1,CCc1c(C(=O)O)ccc(S(C)(=O)=O)c1F.COC(=O)c1ccc2c(c1)CNCCO2>>CCc1c(C(=O)N2CCOc3ccc(C(=O)OC)cc3C2)ccc(S(C)(=O)=O)c1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US20090048249A1,COCc1cccc2c1nc(-c1nn(COCC[Si](C)(C)C)c3ncc(B4OC(C)(C)C(C)(C)O4)cc13)n2COCC[Si](C)(C)C.Cc1ccncc1Br>>COCc1cccc2c1nc(-c1nn(COCC[Si](C)(C)C)c3ncc(-c4cnccc4C)cc13)n2COCC[Si](C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],val
+US20060025599A1,N#C[C@@H]1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1.NO>>N=C(NO)[C@@H]1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1,,CCO,,CCN(C(C)C)C(C)C,Cl,val
+US20070179165A1,CCCC(CCC)n1ccc(=O)c2c(Br)cccc21.Cc1ccc(B(O)O)c(C)c1>>CCCC(CCC)n1ccc(=O)c2c(-c3ccc(C)cc3C)cccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],val
+US20140179715A1,CC(C)(C)OC(=O)N1CCn2c1cc(OCc1ccc(Oc3ccc(F)c(F)c3)c(C(F)(F)F)c1)nc2=O>>O=c1nc(OCc2ccc(Oc3ccc(F)c(F)c3)c(C(F)(F)F)c2)cc2n1CCN2,,CN(C)C=O,,,,val
+US20140235689A1,Cc1nn(C)c(Br)c1-c1c(F)cccc1F.O=Cc1ccc(F)cc1F>>Cc1nn(C)c(C(O)c2ccc(F)cc2F)c1-c1c(F)cccc1F,,C1CCOC1,,[Li]CCCC,,val
+US20070219183A1,CC#CCBr.O=C(Nc1cccc(C2=CCNc3ccnn32)c1)c1cccc(C(F)(F)F)c1>>CC#CCN1CC=C(c2cccc(NC(=O)c3cccc(C(F)(F)F)c3)c2)n2nccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,val
+US20050096337A1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.FC(F)(F)c1ccc(-c2ccc(CCl)c(C3CC3)n2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)nc2C2CC2)cc1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,val
+US04918107,O=S(Cl)Cl.OCc1ccc(OCc2ccccc2)cc1OCc1ccccc1>>ClCc1ccc(OCc2ccccc2)cc1OCc1ccccc1,,c1ccccc1,,,,val
+US20150126484A1,C[Si](C)(C)C#N.Nc1ncnc(N2CCNCC2)c1-c1ccc(F)cc1.O=Cc1cccc(C(F)(F)F)c1>>N#CC(c1cccc(C(F)(F)F)c1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1,,CC#N,,,,val
+US20100261696A1,CC(C)(C)OC(=O)N1CC(C#N)C1.Cn1cnc(S(=O)(=O)Cl)c1>>Cn1cnc(S(=O)(=O)N2CC(C#N)C2)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,val
+US20160039834A1,Cc1noc(C)c1-c1nc(-c2cc(OC[C@@H](CN(C)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C)ccc2Cl)nc(N2Cc3cnn(C4CC4)c3C2)c1C>>CNC[C@@H](O)COc1ccc(Cl)c(-c2nc(-c3c(C)noc3C)c(C)c(N3Cc4cnn(C5CC5)c4C3)n2)c1.O=CO,,C1COCCO1,Cl,,,val
+US20140073606A1,Nc1ncnc2c1ncn2[C@H]1[C@@H](F)[C@H](OC(=O)c2ccccc2)[C@@H](COC(=O)c2ccccc2)C1(O)CO>>C=C1[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H](F)[C@@H]1n1cnc2c(N)ncnc21,,CC#N,,O=C([O-])O.[Na+],,val
+US20050154042A1,COC(=O)C[C@H](O)C[C@H](O)C=Cc1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)n1C(C)C>>COC(=O)C[C@H](O)C[C@H](O)CCc1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)n1C(C)C,[Pd],C1CCOC1,CCO,,,val
+US05262390,COC(=O)C(C)Oc1cc(C)ccc1CCl.Cc1nn(-c2ccc(O)cc2F)c(=O)n1C(F)F>>COC(=O)C(C)Oc1cc(C)ccc1COc1ccc(-n2nc(C)n(C(F)F)c2=O)c(F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20080255386A1,CCCCCN(C)CCC(=O)OC>>CCCCCN(C)CCC(=O)O,,O,,,,val
+US20070060592A1,CCO.O=C(O)c1cccc2c1CC(=CCCN1CCC(O)(c3ccc(Cl)cc3)CC1)c1cccnc1O2.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CCOC(=O)Nc1cccc2c1CC(=CCCN1CCC(O)(c3ccc(Cl)cc3)CC1)c1cccnc1O2,,CCOC(C)=O,,CCN(CC)CC,,val
+US20140249104A1,COc1cnc(C(N)=O)c(CC(OC)OC)c1>>COc1cnc2c(=O)[nH]ccc2c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,val
+US20030232818A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.CCOC(=O)c1cn(CCC#N)c2nc(Cl)c(F)cc2c1=O>>N[C@H]1CCN(c2nc3[nH]cc(C(=O)O)c(=O)c3cc2F)C1,,CC#N,,,,val
+US20140155415A1,CC(C)c1ccccc1[Mg]Br.O=S(=O)(N=Cc1cc2ccccc2o1)c1ccc2c(c1)OCCCO2>>CC(C)c1ccccc1C(NS(=O)(=O)c1ccc2c(c1)OCCCO2)c1cc2ccccc2o1,,CO,,C1CCOC1,,val
+US20050038038A1,CC(C)=O.NCc1ccccc1[N+](=O)[O-]>>CC(C)NCc1ccccc1[N+](=O)[O-],,CO,,Cl,[BH3-]C#N.[Na+],val
+US20160052898A1,Nc1cc(C(=O)Nc2ccc(-c3ccccc3)cc2)ccc1Br.O=C(Cl)CCl>>O=C(CCl)Nc1cc(C(=O)Nc2ccc(-c3ccccc3)cc2)ccc1Br,,ClCCl,,c1ccncc1,,val
+US20150025068A1,COC(=O)c1ccc(NS(=O)(=O)c2cc(-c3ccc4c(c3)OCO4)c(Cl)s2)cc1O>>O=C(O)c1ccc(NS(=O)(=O)c2cc(-c3ccc4c(c3)OCO4)c(Cl)s2)cc1O,,[Na+],[OH-],CCOCC,O,val
+US04874775,CS(=O)(=O)Cl.Cc1ccc(NCc2cccnc2)c(C)c1>>Cc1ccc(N(Cc2cccnc2)S(C)(=O)=O)c(C)c1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,val
+US20150284321A1,Nc1cccc(NC(=O)Nc2ccccc2)c1.O=S(=O)(Cl)c1ccccc1>>O=C(Nc1ccccc1)Nc1cccc(NS(=O)(=O)c2ccccc2)c1,,CCOC(C)=O,,CCN(CC)CC,,val
+US20030036534A1,COC(=O)c1cccc(-c2ccc(C)cc2C(=O)OC)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cccc(-c2ccc(CBr)cc2C(=O)OC)c1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,val
+US07737166B2,COc1c(N)c(C(N)=O)c(C)c(I)c1Br.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1c(Br)c(I)c(C)c(C#N)c1NC(=O)C(F)(F)F,,C1CCOC1,,CCN(CC)CC,,val
+US20050187409A1,CC(=O)c1ccc(C(=O)O)cc1.CC(=O)c1ccc(N)cc1>>CC(=O)c1ccc(NC(=O)c2ccc(C(C)=O)cc2)cc1,CN(C)C=O,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,val
+US20100197668A1,CCCC(N)CCC.CCOC(=O)c1cccn1CCCBr>>CCCC(CCC)NCCCn1cccc1C(=O)OCC,,CC#N,,[I-].[K+],,val
+US20130324516A1,Nc1cc(F)cc(-c2ccc3ncnc(N)c3c2)c1.O=C(O)CN1CCOCC1>>Nc1ncnc2ccc(-c3cc(F)cc(NC(=O)CN4CCOCC4)c3)cc12,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,val
+US20100210662A1,CCOP(=O)(CC#N)OCC.CN1CCC(=O)CC1>>CN1CCC(=CC#N)CC1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],val
+US04013651,C1CCNCC1.CS(=O)(=O)OC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)C(NC(=O)COc3ccccc3)[C@H]2SC1>>O=C(COc1ccccc1)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(N3CCCCC3)CS[C@H]12,,CN(C)C=O,,,,val
+US20140088085A1,CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2N=C(NC(=O)OC(C)(C)C)C1.CN(C)CCN>>CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2N=C(NCCN(C)C)C1,,CCOC(C)=O,CN(C)C=O,,,val
+US20030078426A1,CC(C)c1cccc(C(C)C)c1N=C=O.Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc4cccc(N)c4c3)cc21>>CC(C)c1cccc(C(C)C)c1NC(=O)Nc1cccc2ccc(Oc3ccc4nc(COc5ccc(CC6SC(=O)NC6=O)cc5)n(C)c4c3)cc12,,CN(C)C=O,,,,val
+US20100029611A1,Nc1nc(Cl)ccc1Cl.S=C(Cl)Cl>>S=C=Nc1nc(Cl)ccc1Cl,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,val
+US20110300165A1,CC(C)(C)OC(=O)C1CN(Cc2ccc(/C(N)=N/O)cc2)C1.O=C(F)c1onc(-c2ccccc2)c1C(F)(F)F>>CC(C)(C)OC(=O)C1CN(Cc2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1,,CC#N,,CCN(C(C)C)C(C)C,,val
+US06878700B1,COC(=O)C1CN(C(=O)/C=C/c2ccc(Sc3ccc4c(c3)OCCO4)c(C(F)(F)F)c2)CCN1C(=O)OC>>COC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3ccc4c(c3)OCCO4)c(C(F)(F)F)c2)CC1C(=O)O,,O,,CCO,[Na+].[OH-],val
+US20160052884A1,CCOC(=O)c1ccc(NC(=O)C(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)n2cc(OC)c(-c3cc(Cl)ccc3C#N)cc2=O)cc1>>COc1cn(C(CCO)C(=O)Nc2ccc(C(=O)O)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N,,CO,O,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20140148468A1,NCc1ccc(F)cc1.O=C(O)c1scnc1SCCC(F)(F)c1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)c1scnc1SCCC(F)(F)c1ccc(F)cc1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,val
+US20140228357A1,CI.CN1CCN(C(=O)COc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)CC1>>C[N+]1(C)CCN(C(=O)COc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)CC1.[I-],,CCOCC,,,,val
+US20020137755A1,O=C1NCCN1CCO.O=S(Cl)Cl>>O=C1NCCN1CCCl,,ClC(Cl)Cl,,,,val
+US20050222159A1,CC(C)n1nc(-c2nc(C#N)c(N=CN(C)C)nc2Cl)ccc1=O.OB(O)c1ccc(F)cc1>>CC(C)n1nc(-c2nc(C#N)c(N=CN(C)C)nc2-c2ccc(F)cc2)ccc1=O,,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],val
+US06075037,CCOC(=O)c1[nH]c2ncccc2c1-c1ccc(OC)cc1.ClCc1ccc2c(c1)OCO2>>CCOC(=O)c1c(-c2ccc(OC)cc2)c2cccnc2n1Cc1ccc2c(c1)OCO2,,CN(C)P(=O)(N(C)C)N(C)C,,[H-].[Na+],,val
+US04005217,COC(=O)Nc1ccc(NC(=O)CN(C)C)c([N+](=O)[O-])c1>>COC(=O)Nc1ccc(NC(=O)CN(C)C)c(N)c1,O=[Pt],CO,,[H][H],,val
+US20070111988A1,COC(=O)c1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)c1c-2ccc2cc(OC)ccc12>>COc1ccc2c3c(ccc2c1)-c1ccc(CO)cc1OC3c1ccc(OCCN2CCCCC2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,val
+US20110098299A1,O=C1CCCC2(CCN(c3cccc(Cl)c3)C2=O)C1.[NH4+]>>CN1CCC2(CCCC(N)C2)C1=O,,CO,,[BH3-]C#N.[Na+],,val
+US20050014822A1,CC(=O)OC(C)=O.COc1ccc(N)cc1NC(=O)NC(=O)c1cc(F)c(F)cc1Cl>>COc1ccc(NC(C)=O)cc1NC(=O)NC(=O)c1cc(F)c(F)cc1Cl,,O,,CN1CCCC1=O,,val
+US20100266714A1,C[C@@H](NS(=O)C(C)(C)C)c1ccc(F)cn1>>C[C@@H](N)c1ccc(F)cn1,,CO,,Cl,,val
+US06878704B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C(=O)OC(C)(C)C)CC3)cc21,,C1CCOC1,O,[Na+].[OH-],,val
+US20140323470A1,CCN(C(C)C)C(C)C.C[C@H]1CCCCN1c1nnc2ccc(O[C@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(OCCO)c4)c4ccccc43)cn12>>C[C@H]1CCCCN1c1nnc2ccc(O[C@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(OCCN(C)C)c4)c4ccccc43)cn12,,ClCCl,,CS(=O)(=O)Cl,,val
+US20150126485A1,CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1ccc(N2C[C@H](O)[C@@H](O)C2)c(Br)c1>>O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1ccc(N2C[C@H](O)[C@@H](O)C2)c(-c2ccn[nH]2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,COCCOC,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],val
+US20150025065A1,Br.CN=S1(=O)CC2CN(C(=O)OCc3ccccc3)CC2C1>>Br.CN=S1(=O)CC2CNCC2C1,,CC(=O)O,,,,val
+US20130190289A1,COC(=O)[C@H](COCCN(C)C(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CNCCOC[C@H](NC(=O)OCc1ccccc1)C(=O)OC,,ClCCl,O=C(O)C(F)(F)F,,,val
+US20140031360A1,CC(C)N.COc1ccc(COc2cc(-c3c[nH]c4ccc(-c5cncc(C6CC6)n5)cc34)nc(S(C)(=O)=O)n2)cc1>>COc1ccc(COc2cc(-c3c[nH]c4ccc(-c5cncc(C6CC6)n5)cc34)nc(NC(C)C)n2)cc1,,CN1CCCC1=O,O,,,val
+US20130137675A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ccnn1-c1ccccc1>>CC(C)(C)OC(=O)Nc1ccnn1-c1ccccc1,,CO,,[Na+].[OH-],,val
+US06399773B1,COc1cc([N+](=O)[O-])ccc1Cl.c1nc[nH]n1>>COc1cc([N+](=O)[O-])ccc1-n1cncn1,,CS(C)=O,,[K+].[OH-],,val
+US20040059132A1,CI.COc1ccc(CN2C(=O)C(C)(c3cc(CO)ccc3Cl)c3cc(Cl)ccc32)c(OC)c1>>COCc1ccc(Cl)c(C2(C)C(=O)N(Cc3ccc(OC)cc3OC)c3ccc(Cl)cc32)c1,,C1CCOC1,,[H-].[Na+],,val
+US20040034046A1,C=O.COc1cc2c(Nc3cccc4c3OCO4)ncnc2cc1OCCC1(O)CCNCC1>>COc1cc2c(Nc3cccc4c3OCO4)ncnc2cc1OCCC1(O)CCN(C)CC1,,O=CO,,[Na+].[OH-],,val
+US06887881B1,CC(C)(C)OC(=O)N1CC2CNCC(C2)C1.N#Cc1ccc(OCC2CN2C(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CC2CC(CN(CC(COc3ccc(C#N)cc3)NC(=O)OCc3ccccc3)C2)C1,,CC(C)O,,,,val
+US03980788,CC(=O)OC(C)=O.CNC1CCCN(C2c3ccccc3Oc3ccccc32)C1>>CC(=O)N(C)C1CCCN(C2c3ccccc3Oc3ccccc32)C1,,ClC(Cl)Cl,,CCN(CC)CC,,val
+US20030162798A1,CC(C)Cn1c(=O)n(C)c(=O)c2c(C#CCCCO)n(Cc3cccc4ccccc34)cc21>>CC(C)Cn1c(=O)n(C)c(=O)c2c(CCCCCO)n(Cc3cccc4ccccc34)cc21,[Pd],CCO,,[H][H],,val
+US05801170,CN(C)CCCl.COc1ccccc1N>>COc1ccccc1NCCN(C)C,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],val
+US20160244815A1,CCC(=O)Oc1cc[c-](CC)c1.[Fe+2].c1cc[cH-]c1>>OCCC[c-]1cccc1.[Fe+2].c1cc[cH-]c1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,val
+US20040006083A1,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)c1cc2ccccc2n1C.Nc1ncnc2c1c(I)nn2C1CCNC1>>COc1cc(-c2nn(C3CCNC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,Cl,O=C([O-])[O-].[Na+].[Na+],val
+US20060247287A1,C=CC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C.Nc1ccnc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1>>CC(C)(C)OC(=O)CC[C@@H](NC(=O)OC(C)(C)C)C(=O)CCNc1ccnc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1,,CC#N,ClCCl,CCN(C(C)C)C(C)C,Cl,val
+US20100022538A1,Nc1nc(O)ncc1F.O=S(=O)(Cl)c1ccccc1>>Nc1nc(OS(=O)(=O)c2ccccc2)ncc1F,,c1ccncc1,,,,val
+US05399291,CCCCCCCCCCOc1ccc(C(=O)O)cc1.CCCCOCC(F)(F)C(F)(F)C(F)(F)COc1ccc(O)cc1>>CCCCCCCCCCOc1ccc(C(=O)Oc2ccc(OCC(F)(F)C(F)(F)C(F)(F)COCCCC)cc2)cc1,CN(C)c1ccncc1,ClCCl,,,,val
+US20100105900A1,CI.CN(C)C[C@@H](CC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(Oc2ccccc2)nc1>>C[N+](C)(C)C[C@@H](CC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(Oc2ccccc2)nc1.[I-],,ClCCl,,,,val
+US20160083365A1,CC(=O)OC(C)=O.Nc1ccnc(Cl)n1>>CC(=O)Nc1ccnc(Cl)n1,,CN(C)C=O,,[H-].[Na+],,val
+US20160222012A1,C=CCC(c1cc2ccc(F)cc2nc1Cl)N(CC=C)C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CC=CCC1c1cc2ccc(F)cc2nc1Cl,,ClCCl,,Cl,O=C([O-])O.[Na+],val
+US20050244332A1,COc1cc(CC(=O)c2ccc3c(c2)C=CC(C)(C)O3)cc(OC)c1OCc1ccccc1>>COc1cc(CC(=O)c2ccc3c(c2)CCC(C)(C)O3)cc(OC)c1O,[Pd],CO,,,,val
+US20030225064A1,COB(OC)OC.Cc1ccc(Br)s1>>Cc1ccc(B(O)O)s1,,C1CCOC1,,Cl,[Li]CCCC,val
+US20040092737A1,CCOC(=O)C1C2CNCC21.ClCc1ccc2c(c1)Nc1nccnc1S2>>CCOC(=O)C1C2CN(Cc3ccc4c(c3)Nc3nccnc3S4)CC21,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])O.[Na+],val
+US20040236109A1,CC(=O)C1(C)CC=C(C(=O)N2c3ccccc3C(C)CC2(C)C)C=C1N.O=C(Cl)c1ccco1>>CC(=O)C1(C)CCC(C(=O)C2=C(C)c3ccccc3NC2(C)C)C=C1NC(=O)c1ccco1,,C1CCOC1,,CCN(C(C)C)C(C)C,,val
+US20030229066A1,NCCCn1ccnc1.NC[C@@H]1C[C@H]1CN1CCN(c2csc3cc(C(F)(F)F)ccc23)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(NCCCn1ccnc1)NC[C@@H]1C[C@H]1CN1CCN(c2csc3cc(C(F)(F)F)ccc23)CC1,,C1CCOC1,,CCN(CC)CC,,val
+US20140243283A1,O=C(OO)c1cccc(Cl)c1.O=C1CCC2(CC1)c1cc(Br)ccc1-c1ccc(Br)cc12>>O=C1CCC2(CCO1)c1cc(Br)ccc1-c1ccc(Br)cc12,,ClCCl,,O=C([O-])O.[Na+],,val
+US20150148340A1,CCI.CCOC(=O)c1cn(-c2ccc3c(c2)[nH]c(=O)n3C)c(=O)n(Cc2cccc(Cl)c2C(F)(F)F)c1=O>>CCOC(=O)c1cn(-c2ccc3c(c2)n(CC)c(=O)n3C)c(=O)n(Cc2cccc(Cl)c2C(F)(F)F)c1=O,,CN(C)C=O,O,[I-].[K+],,val
+US06306852B1,COC(=O)C(c1cc(OC)c2c(c1)OCO2)c1c[nH]c2cc(Br)ccc12.COS(=O)(=O)c1ccc(C)cc1>>COC(=O)C(c1cc(OC)c2c(c1)OCO2)c1cn(C)c2cc(Br)ccc12,,CN(C)C=O,,[H-].[Na+],,val
+US06136823,CN.COc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)ccc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3ccc(F)c(OC)c3)c2c1Cl,,c1ccncc1,,,,val
+US20070275987A1,CCc1cnc(Cl)c(C(=O)NC(=N)COCCc2cc(F)ccc2F)c1>>CCc1cnc2nc(COCCc3cc(F)ccc3F)[nH]c(=O)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20150376233A1,C=CCCCC[C@@H](COC)[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)OC>>C=CCCCC[C@@H](COC)[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)O,,C1CCOC1,O,CO,[Li+].[OH-],val
+US20030171428A1,CON(C)C(=O)c1cc(O)cc2cc(-c3ccc(O)cc3)oc12>>O=Cc1cc(O)cc2cc(-c3ccc(O)cc3)oc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,val
+US20070060607A1,CCOC(=O)c1cnc(N)c2c(COc3cccc(COc4ccc(Cl)cc4)c3)csc12.NCCO>>Nc1ncc(C(=O)NCCO)c2scc(COc3cccc(COc4ccc(Cl)cc4)c3)c12,,CS(C)=O,,,,val
+US20050282808A1,CC(C)(C)OC(=O)Nc1cccc2oc(C(=O)Nc3ccc(Cl)cn3)c(NC(=O)[C@@H]3CC[C@@H](N4CCCC4=O)CC3)c12>>Nc1cccc2oc(C(=O)Nc3ccc(Cl)cn3)c(NC(=O)[C@@H]3CC[C@@H](N4CCCC4=O)CC3)c12,,O=C(O)C(F)(F)F,,,,val
+US04826866,CCCCCCCNC(=S)NN.CCOC(=O)C(Cl)C(C)=O>>CCCCCCCNc1n[nH]c(C)c1C(=O)OCC.Cl,,CCO,,,,val
+US20150344446A1,NN.O=C(O)CCCc1cccc(Br)c1>>NNC(=O)CCCc1cccc(Br)c1,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,val
+US20100120741A1,Nc1cc(Cl)ccc1[N+](=O)[O-].O=N[O-]>>NNc1cc(Cl)ccc1[N+](=O)[O-],,Cl,O,Cl[Sn]Cl,,val
+US20100305104A1,C1CCNC1.CCOC(=O)c1ccc(F)c([N+](=O)[O-])c1>>O=C(O)c1ccc(N2CCCC2)c([N+](=O)[O-])c1,,C1CCOC1,CN(C)C=O,O,[Li+].[OH-],val
+US20110028445A1,Cc1ccnc(C#Cc2ccccc2)c1>>Cc1ccnc(CCc2ccccc2)c1,[Pd],CO,,,,val
+US20160222060A1,O=C(N[C@H](CO)Cc1ccccc1)OCc1ccccc1>>O=C[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,ClCCl,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,val
+US20070213331A1,CC(=O)N1[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@H]2C[C@@H](OCc3cccc(OC(F)(F)F)c3)CN2C(=O)OC(C)(C)C)OC1(C)C.Cl>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1C[C@@H](OCc2cccc(OC(F)(F)F)c2)CN1.Cl,,C1COCCO1,,,,val
+US20060069145A1,CCN1C(=O)C(C)(C)c2cc3c(cc21)nc(C(=O)C=C(SC)SC)n3C1CCCCO1.NN>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4cc(SC)[nH]n4)nc3cc21,,CC#N,,O,,val
+US20140056849A1,CC(C)C(=O)Cl.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F>>CCCS(=O)(=O)N(C(=O)C(C)C)c1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F,,ClC(Cl)Cl,,CCN(CC)CC,,val
+US20010006969A1,C=CCN.Cc1csc2c(NNC(C)(C)C)nc(Cl)nc12>>C=CCNc1nc(NNC(C)(C)C)c2scc(C)c2n1,,CCCCCC,CCOC(C)=O,O=C([O-])O.[Na+],,val
+US20030232875A1,O=C1NC(=O)c2ccccc21.OCc1nocc1-c1ccccc1>>O=C1c2ccccc2C(=O)N1Cc1nocc1-c1ccccc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,val
+US20080139610A1,COc1ccc2c(c1)CCNC2.Cc1cc(Br)cc(C)c1NC(=O)CC(C)(C)C>>COc1ccc2c(c1)CCN(c1cc(C)c(NC(=O)CC(C)(C)C)c(C)c1)C2,,Cc1ccccc1,,Cl,CC(C)(C)[O-].[K+],val
+US04391821,CC(C)N.c1ccc(C2COc3cc(OCC4CO4)ccc3C2)cc1>>CC(C)NCC(O)COc1ccc2c(c1)OCC(c1ccccc1)C2,,CCO,,,,val
+US20160229843A1,COc1cncc(-c2ccc(N)c(O)c2)c1.Cc1cc(C(F)(F)F)[nH]n1>>COc1cncc(-c2ccc3nc(-c4cc(C)n[nH]4)oc3c2)c1,,CO,,O,[Na+].[OH-],val
+US04698094,CCOC(=O)CS.O=C(Cl)Cc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1>>CCOC(=O)CSC(=O)Cc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1,,CC(=O)N(C)C,,CCN(CC)CC,O,val
+US20040259910A1,CCOc1cccc(C(=O)c2ncc(C=O)c3cc(OCCCOC(C)=O)c(OC)cc23)c1.O>>CCOc1cccc(C(=O)c2ncc(C(=O)O)c3cc(OCCCOC(C)=O)c(OC)cc23)c1,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,val
+US05880147,CC(C)(C)c1ccc(/C=C/CO[Si](C)(C)C(C)(C)C)cc1[N+](=O)[O-]>>CC(C)(C)c1ccc(CCCO[Si](C)(C)C(C)(C)C)cc1N,[Pd],CCOCC,,[H][H],,val
+US20090281140A1,C=CCCCCN(C)C(=O)C1CC(Oc2cc(-c3cccc(C)n3)nc3c(C)c(OC)ccc23)CC1C(=O)NC1(C(=O)OCC)CC1C=C>>CCOC(=O)C12CC1C=CCCCCN(C)C(=O)C1CC(Oc3cc(-c4cccc(C)n4)nc4c(C)c(OC)ccc34)CC1C(=O)N2,,ClCCCl,,,,val
+US20040266774A1,COC(=O)c1cccc(-c2cccs2)c1>>O=C(O)c1cccc(-c2cccs2)c1,,C1CCOC1,CO,Cl,[Na+].[OH-],val
+US04810719,CC(=O)OC(C)=O.Oc1ccc(Nc2ccn(-c3ccccc3)n2)cc1>>CC(=O)Oc1ccc(Nc2ccn(-c3ccccc3)n2)cc1,,O,,O=S(=O)(O)O,,val
+US20150336962A1,COc1ccc(Cl)cc1-c1nc(Br)sc1NC(=O)c1cnn2cccnc12>>O=C(Nc1sc(Br)nc1-c1cc(Cl)ccc1O)c1cnn2cccnc12,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],val
+US20040122057A1,CC(C)I.COC(C(=O)NCc1ccc(C#N)cc1)c1c(F)ccc(N)c1F>>COC(C(=O)NCc1ccc(C#N)cc1)c1c(F)ccc(NC(C)C)c1F,,C1CCOC1,O,CCN(C(C)C)C(C)C,CN(C)C=O,val
+US20090118501A1,CCOC(=O)CSc1cnc(NC(=O)N(C2CCCCC2)[C@@H]2CC[C@@H](COc3ccccc3)CC2)s1>>O=C(O)CSc1cnc(NC(=O)N(C2CCCCC2)[C@@H]2CC[C@@H](COc3ccccc3)CC2)s1,,C1CCOC1,,Cl,[Na+].[OH-],val
+US20120041024A1,Cc1[nH]nc(NC=O)c1C>>CNc1n[nH]c(C)c1C,,C1CCOC1,,B,,val
+US20030092677A1,Cc1ccc(-c2ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c2)cc1>>Cc1ccc(-c2ccc(NC(=O)OC(C)(C)C)c(N)c2)cc1,[Pd],,,,,val
+US20070078164A1,CCOC(=O)N1CC[C@](O)(c2cccc(-c3ccccc3)c2)[C@@H](O)C1>>CCOC(=O)N1CC[C@H](c2cccc(-c3ccccc3)c2)[C@@H](O)C1,[Ni],CCO,,,,val
+US20090149501A1,CS(=O)(=O)Cl.OCCc1cccnc1>>CS(=O)(=O)OCCc1cccnc1,,C1CCOC1,,CCN(CC)CC,,val
+US20100174065A1,COC(=O)c1cc(Br)ccc1OCCNC(=O)OC(C)(C)C>>O=C1NCCOc2ccc(Br)cc21,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,val
+US20020086879A1,CC(C)(C)OC(=O)N1CC[C@H](CN)[C@H](O)C1.Nc1c(Cl)cc(C(=O)n2ccnc2)c2c1CCO2>>CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)c2cc(Cl)c(N)c3c2OCC3)[C@H](O)C1,,CC#N,,,,val
+US20020006948A1,COC(=O)CCCCCBr.O=S(=O)(Nc1ccc2c(c1)nc(-c1ccccc1)n2-c1ccccc1)c1ccc(C(F)(F)F)cc1>>COC(=O)CCCCCN(c1ccc2c(c1)nc(-c1ccccc1)n2-c1ccccc1)S(=O)(=O)c1ccc(C(F)(F)F)cc1,,CN(C)C=O,,O,[H-].[Na+],val
+US20050049290A1,CC(C)CN(CC(C)C)C(=O)c1ccc(NCCCN(C)CCc2ccccn2)c([N+](=O)[O-])c1>>CC(C)CN(CC(C)C)C(=O)c1ccc(NCCCN(C)CCc2ccccn2)c(N)c1,[Pd],CCO,CCOC(C)=O,,,val
+US05824802,CCC1CN(c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(CC)c3O)c2Cl)CC(O)O1.CO>>CCC1CN(c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(CC)c3O)c2Cl)CC(OC)O1,,CO,ClCCl,CC(=O)Cl,,val
+US20070072879A1,N#Cc1ccnc(N)c1.NO>>N=C(NO)c1ccnc(N)c1,,CCO,O,Cl,O=C([O-])[O-].[Na+].[Na+],val
+US20140088079A1,CC1(C)OB(c2ccc3c(c2)CCC3)OC1(C)C.Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1CBr>>Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc2c(c1)CCC2,,CCO,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20060211734A1,CC1CC(Oc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CCN1C(=O)OC(C)(C)C>>CC1CC(Oc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CCN1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,val
+US20060074095A1,CCCN.Clc1nc(Cl)c2[nH]cnc2n1>>CCCNc1[nH]c(Cl)nc2ncnc1-2,,CCCCO,,,,val
+US04070481,CCCCCCCCCCCC(=O)O.Oc1cccc2c(Cl)cccc12>>CCCCCCCCCCCC(=O)c1ccc2c(Cl)cccc2c1O,,O,,,,val
+US20090247571A1,CCC(N)CC.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CCC(CC)Nc1nc(Cl)ccc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,val
+US20030036618A1,CO.O=[N+]([O-])c1c(F)c(F)c(F)c(F)c1F>>COc1c(F)c(F)c([N+](=O)[O-])c(F)c1F,,CO,,C[O-].[Na+],,val
+US20090093484A1,CCOC(=O)CBr.COc1ccc(O)c2ccoc12>>CCOC(=O)COc1ccc(OC)c2occc12,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,val
+US20120115813A1,CC(C)(C)OC(=O)NCCCCOc1cccc2c1B(O)OC2C[N+](=O)[O-].O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)NCCCCOc1ccc(Cl)c2c1B(O)OC2C[N+](=O)[O-],,CN(C)C=O,,,,val
+US20060111375A1,C1CCNCC1.COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCCl>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCN1CCCCC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],val
+US20120010188A1,Nc1ccc(Cl)cn1.O=C(CBr)c1ccc(Br)cc1>>Br.Clc1ccc2nc(-c3ccc(Br)cc3)cn2c1,,CCO,,,,val
+US20050085519A1,O=C(Nc1ccccc1[N+](=O)[O-])c1cc([N+](=O)[O-])ccc1Cl>>Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)c1,[Fe],CC(=O)O,Cc1ccccc1,,,val
+US20120134934A1,CC(C)(C)OC(=O)NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1F.O=C(CBr)c1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)O[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)c1ccccc1F.[Br-],,CC#N,CCOC(C)=O,,,val
+US20010056100A1,COC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccc(COc2ccccc2)cc1>>O=C(N[C@H](Cc1ccccc1)C(=O)O)OCc1ccc(COc2ccccc2)cc1,,CO,O,[Li+].[OH-],,val
+US20160016948A1,CO[C@H]1CCN(c2nccc(Nc3cc4c(cn3)c(-c3[nH]ncc3C)cn4C(C)C)n2)C[C@H]1F.OCCBr>>CO[C@H]1CCN(c2nccc(Nc3cc4c(cn3)c(-c3nn(CCO)cc3C)cn4C(C)C)n2)C[C@H]1F,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],val
+US20050277670A1,CC(C)(C)OC(=O)N1CCC(C(O)c2ccc(Br)cc2)CC1.Oc1ccccc1>>CC(C)(C)OC(=O)N1CCC(C(Oc2ccccc2)c2ccc(Br)cc2)CC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,val
+US20120149677A1,O=Cc1cc(Cl)cnc1Oc1ccc2c(nnn2CC2CC2)c1Br>>OCc1cc(Cl)cnc1Oc1ccc2c(nnn2CC2CC2)c1Br,,CCO,,[BH4-].[Na+],,val
+US20050187247A1,COc1cc2c(Cl)c(C#N)cnc2cc1OCCCCl.Cn1ccnc1Sc1ccc(N)cc1Cl>>COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1OCCCCl,,CCOCCO,,Cl,c1ccncc1,val
+US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccccc4F)nc(Cl)c3n2)cc1.Nc1ccc(N2CCOCC2)cc1>>Fc1ccccc1-c1nc(Nc2ccc(N3CCOCC3)cc2)c2[nH]ncc2n1,C1COCCO1,CO,,Cl,,val
+US20040162435A1,CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCC.CN1CCCC1CCN>>CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCC1CCCN1C,,CCOC(C)=O,O,Cc1ccccc1,[Na+].[OH-],val
+US20060229254A1,C=[N+]=[N-].CC(=O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)[C@H](CCC(C)=O)NC(=O)OCc1ccccc1,,C1CCOC1,,,,val
+US05998452,CC(C)c1cc(C2SCC(=O)N2CCCO)cc(C(C)C)c1O.O=S(Cl)Cl>>CC(C)c1cc(C2SCC(=O)N2CCCCl)cc(C(C)C)c1O,,ClCCl,,,,val
+US20060142360A1,N#Cc1ccc(N(CCCS(=O)(=O)c2ccc(OCc3ccccc3)cc2)n2cnnc2)cc1>>N#Cc1ccc(N(CCCS(=O)(=O)c2ccc(O)cc2)n2cnnc2)cc1,[Pd],C1CCOC1,CCO,,,val
+US20070088029A1,O=C(Cl)CCCCBr.OCc1ccccc1>>O=C(CCCCBr)OCc1ccccc1,,CCOC(C)=O,O,CCN(CC)CC,ClCCl,val
+US20130210809A1,COCC(=O)C(=CN(C)C)C(=O)OC.NN>>COCc1n[nH]cc1C(=O)OC,,CCCCO,,CC(=O)O,O,val
+US20120088755A1,Cc1cc(O)cc2[nH]c(C3CC3)nc12.Clc1cc(Cl)ncn1>>Cc1cc(Oc2cc(Cl)ncn2)cc2[nH]c(C3CC3)nc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20090042852A1,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.O=C=NS(=O)(=O)c1ccccc1Cl>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccccc3Cl)CC2)nc1C(F)(F)F,,ClCCl,,,,val
+US05504107,CO.COC=CC[C@H]1OC(C)(C)OC1=O>>COC(=O)[C@H]1CCC(OC)O1,,CO,,,,val
+US04186019,Nc1ccccn1.O=S(=O)(O)Cl.c1ccccc1>>O=S(=O)(Nc1ccccn1)c1ccccc1,,C1CCOC1,,O,,val
+US04695575,Fc1ccc(Cn2c(Cl)nc3ccccc32)cc1.NC(N)=S>>Fc1ccc(Cn2c(S)nc3ccccc32)cc1,,CCO,,,,val
+US20080319080A1,N#Cc1cc(F)c(F)c(F)c1.OCc1ccccc1>>N#Cc1cc(F)c(OCc2ccccc2)c(F)c1,,CN(C)C=O,,Cl,[H-].[Na+],val
+US20090062268A1,C[C@@H](c1ccccc1)N1C[C@@H]2CCC[C@@]1(c1nc3c(C(=O)O)cccc3[nH]1)C2.N>>C[C@@H](c1ccccc1)N1C[C@@H]2CCC[C@@]1(c1nc3c(C(N)=O)cccc3[nH]1)C2,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,val
+US20040122050A1,O=S(=O)(NC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CC[C@@H](O)C1>>O=C1CCN(S(=O)(=O)NC2CCC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CC2)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,val
+US20090048269A1,Cc1ccc(O)c(Cl)n1.Clc1cc(I)ccn1>>Cc1ccc(Oc2ccnc(Cl)c2)c(Cl)n1,I[Cu]I,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,val
+US20080318968A1,Cc1cnc(NC(=O)c2cc(OCc3ccccc3)cc(O[C@@H](C)COC(F)F)c2)cn1>>Cc1cnc(NC(=O)c2cc(O)cc(O[C@@H](C)COC(F)F)c2)cn1,,CCO,,,,val
+US20080090794A1,C1COCCN1.COC(=O)C(Br)c1ccccc1>>COC(=O)C(c1ccccc1)N1CCOCC1,,CC#N,,CCN(CC)CC,O,val
+US20060004049A1,CO.Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@H](NC(=O)[C@H]2CCCN(C(=O)OC(C)(C)C)C2)C1>>CC(=O)N1CCC[C@H](C(=O)N[C@H]2CCCN(S(=O)(=O)c3cccc(Cl)c3C)C2)C1,,C1COCCO1,CO,Cl,O=C(O)C(F)(F)F,val
+US20110105436A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1cccc(Nc2nc(-c3ccncc3)c(C=O)s2)c1>>COC(=O)/C=C/c1sc(Nc2cccc(C)c2)nc1-c1ccncc1,,ClCCl,,,,val
+US20160136076A1,NCCCCCO.O=C(Cl)c1cccnc1>>O=C(NCCCCCO)c1cccnc1,,O,,ClCCl,,val
+US20100056374A1,COc1ccc(CC#N)c(C)c1.Cl>>COc1ccc(CCN)c(C)c1.Cl,[Pd],CCO,,[H][H],,val
+US20120270870A1,CS(=O)(=O)Cl.OCc1ccnc(Br)c1>>CS(=O)(=O)OCc1ccnc(Br)c1,,ClCCl,,CCN(C(C)C)C(C)C,,val
+US04638088,Cc1cc([N+](=O)[O-])c(C)c(Cl)c1Oc1ccc(-c2ccccc2)cc1Cl>>Cc1cc(N)c(C)c(Cl)c1Oc1ccc(-c2ccccc2)cc1Cl,[Pt],Cc1ccccc1,,,,val
+US20150368245A1,CI.CN(C)C=O.O=C(O)[C@@H]1CC[C@@H](C(=O)O)CC1>>COC(=O)[C@@H]1CC[C@@H](C(=O)OC)CC1,,O,,CCOCC,O=C([O-])[O-].[K+].[K+],val
+US20070293515A1,CC(C)(C)OC(=O)N[C@H]1CC[C@H](C(=O)O/N=C(\N)c2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CC[C@H](c2nc(-c3ccccc3)no2)C1,,CCO,O,CC(=O)[O-].[Na+],,val
+US20150368210A1,CC(C)(C)OC(=O)[C@H]1CC(NCc2ccc(-c3cnc(N)c(NCc4c(Cl)cccc4Cl)n3)cc2)CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@H]1CC(NCc2ccc(-c3cnc(N)c(NCc4c(Cl)cccc4Cl)n3)cc2)CCN1,,C1COCCO1,,Cl,[Na+].[OH-],val
+US20150141406A1,COc1ncc(C#N)c2c1c(-c1cn[nH]c1)cn2C1CCCC1.NC(=O)CBr>>COc1ncc(C#N)c2c1c(-c1cnn(CC(N)=O)c1)cn2C1CCCC1,,C1CCOC1,,O,[H-].[Na+],val
+US05684031,CC(C)(C)c1cc(N)cc2c1SCC2(C)C.O=S(=O)(O)C1=NCCN1>>CC(C)(C)c1cc(NC2=NCCN2)cc2c1SCC2(C)C,,CC#N,,,,val
+US06057369,COc1ccc(SC(CCCCc2ccccc2)C(C)C(=O)O)cc1.C[Si](C)(C)ON>>COc1ccc(SC(CCCCc2ccccc2)C(C)C(=O)NO)cc1,,ClCCl,,O=C(Cl)C(=O)Cl,,val
+US20080076745A1,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)NCCNC(=O)OC(C)(C)C,[Pd],CCO,,,,val
+US20010039286A1,CI.CN(C)C=O.COC(=O)CCc1c(-c2ccc(Cl)cc2)[nH]c2ccc(C(F)(F)F)cc12.O>>COC(=O)CCc1c(-c2ccc(Cl)cc2)n(C)c2ccc(C(=O)OC)cc12,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],val
+US20080312208A1,CCOC(=O)c1cc(Cl)c(Cl)nc1C.O=C(NS(=O)(=O)Cc1ccccc1)C1CNC1>>CCOC(=O)c1cc(Cl)c(N2CC(C(=O)NS(=O)(=O)Cc3ccccc3)C2)nc1C,,CCO,ClCCl,CC#N,O,val
+US20090275578A1,COC(=O)c1c(Cl)cccc1CBr.NCCCc1ccccc1>>O=C1c2c(Cl)cccc2CN1CCCc1ccccc1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],val
+US20150152118A1,O=C(OCc1ccccc1)[C@H]1CC[C@H](N2CCN(c3ccc(F)cc3)CC2)C1>>O=C(O)[C@H]1CC[C@H](N2CCN(c3ccc(F)cc3)CC2)C1,[Pd],CO,,,,val
+US04405357,CC(C)(C)C(=O)Cl.ONCc1ccccc1Cl>>CC(C)(C)C(=O)N(O)Cc1ccccc1Cl,,ClCCl,,c1ccncc1,,val
+US05849755,COc1ccc(Cl)cc1C(=O)Cl.COc1ccc2c(c1)OCC(N)C2>>COc1ccc2c(c1)OCC(NC(=O)c1cc(Cl)ccc1OC)C2,,c1ccncc1,,Cl,,val
+US20100087437A1,Nc1ccc(C(=O)N2CCOC(c3ccccc3)C2)cc1.O=Cc1ccccc1>>O=C(c1ccc(NCc2ccccc2)cc1)N1CCOC(c2ccccc2)C1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,val
+US06291455B1,COc1cc2ncnc(Cl)c2cc1OC.Cl.Nc1cc(O)ccc1F>>COc1cc2ncnc(Nc3cc(O)ccc3F)c2cc1OC.Cl,,CC(C)O,,,,val
+US20110237607A1,CC(=O)CC(C)=O.Cn1cnc2c(NC3Cc4ccccc4C3)nc(NN)nc21>>Cc1cc(C)n(-c2nc(NC3Cc4ccccc4C3)c3ncn(C)c3n2)n1,,CCO,,,,val
+US20160151249A1,C=C(C)C(=O)OCCNC(=O)NCCCCCCP(=O)(OCC)OCC>>C=C(C)C(=O)OCCNC(=O)NCCCCCCP(=O)(O)O,,ClCCl,,C[Si](C)(C)Br,,val
+US05068367,N#CC1=C(C#N)C(=O)C(C#N)=C(C#N)C1=O.c1ccc2c(c1)Cc1ccccc1C2>>N#CC1=C(C#N)C(=O)C(C#N)=C(C#N)C1=O.c1ccc2cc3ccccc3cc2c1,,CC#N,,,,val
+US04985444,Cc1nnccc1-c1c(-c2ccccc2)nn2ccccc12.OC(O)C(Cl)(Cl)Cl>>OC(Cc1nnccc1-c1c(-c2ccccc2)nn2ccccc12)C(Cl)(Cl)Cl,,O,,ClCCl,c1ccncc1,val
+US05308853,CCCCc1ncc(/C=C2\C(=O)NC(=O)N2CCCC)n1Cc1ccc(C(=O)OC)cc1.Cc1nc(CCl)cs1.Cl>>CCCCc1ncc(/C=C2\C(=O)N(Cc3csc(C)n3)C(=O)N2CCCC)n1Cc1ccc(C(=O)OC)cc1.Cl.Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US20050256140A1,Cn1cnc(-c2ccccc2)c1-c1cc2c(S(C)(=O)=O)ncnc2s1.N>>Cn1cnc(-c2ccccc2)c1-c1cc2c(N)ncnc2s1,,C1COCCO1,,,,val
+US20120065210A1,C=O.CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)c(C(F)(F)F)c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F>>CC(C)(C)C[C@@H]1N2CN(c3ccc(C(=O)O)c(C(F)(F)F)c3)C(=O)[C@H]2[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,O,,COCCOC,,val
+US20120046419A1,C=C.C=CCCCCC=C.C=CCCCCCC>>C=C.C=CCCCCC=C.C=CCCCCCC,,Cc1ccccc1,,,,val
+US20040248941A1,CCOC(=O)OC(C)n1c(SCc2nccc(OCC(F)(F)F)c2C)nc2ccccc21.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)OC(C)n1c(S(=O)Cc2nccc(OCC(F)(F)F)c2C)nc2ccccc21,,ClCCl,,,,val
+US20090093518A1,CC(C)Br.Cc1c[nH]c(=O)c2cc(F)c(OC3CCNCC3)cc12>>Cc1c[nH]c(=O)c2cc(F)c(OC3CCN(C(C)C)CC3)cc12,,CN(C)C=O,,CCN(CC)CC,,val
+US20100216839A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)c1c(F)cccc1F>>NC(=S)c1c(F)cccc1F,,Cc1ccccc1,,,,val
+US20030139418A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(SCc2ccccc2OCc2ccccc2)cc1>>O=C(Cl)c1ccc(SCc2ccccc2OCc2ccccc2)cc1,,ClCCl,,,,val
+US06479519B1,CCOC(=O)CCc1ccc(N)cn1.COc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1C>>CCOC(=O)CCc1ccc(NC(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US05440065,C=CC(CCC(=O)OCC)NC(=O)C(Cl)(Cl)Cl>>C=CC(N)CCC(=O)O,,Cl,,,,val
+US08247377B2,C=COC(=O)CCC.OCC(O)(CO)C(F)(F)F>>CCCC(=O)OC[C@@](O)(CO)C(F)(F)F,,COC(C)(C)C,,,,val
+US20140330026A1,CCOC(=O)C(C)C(=O)OCC.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>CCOC(=O)C(C)(C(=O)OCC)c1c(F)cc([N+](=O)[O-])cc1F,,CN(C)C=O,,[Na+].[OH-],,val
+US04349568,COc1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1>>CS(=O)(=O)c1ccc(Oc2ccc(O)cc2)cc1,,CC(=O)O,,Br,,val
+US20150175541A1,CO.Cl.N[C@@H](CO)CC(=O)O>>COC(=O)C[C@@H](N)CO.Cl,,CO,,C1COCCO1,,val
+US06162808,COC(=O)C[C@H](NC(=O)Cc1csc(N)n1)C(=O)OC.Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2ccc(C(=O)O)o2)c(=O)[nH]c1=S>>COC(=O)C[C@H](NC(=O)Cc1csc(NC(=O)c2ccc(Cn3cc(C4c5ccc(C)cc5C=Cc5cc(C)ccc54)c(=S)[nH]c3=O)o2)n1)C(=O)OC,CN(C)c1ccncc1,CN(C)C=O,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,val
+US20020156081A1,COc1cc(-c2nn([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1N.O=C(Cl)[C@@H]1C[C@H]1c1ccccc1>>COc1cc(-c2nn([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)[C@H]1C[C@@H]1c1ccccc1,,c1ccncc1,,,,val
+US20110028450A1,CCCC[Sn](CCCC)(CCCC)c1cnccn1.COc1cc2c(cc1Br)-c1c(-c3cccs3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCOC3>>COc1cc2c(cc1-c1cnccn1)-c1c(-c3cccs3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCOC3,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCOCC,,val
+US20100105665A1,C1CCNCC1.O=C(Br)c1cccc(CBr)c1>>O=C(c1cccc(CBr)c1)N1CCCCC1,,c1ccccc1,,,,val
+US20140221435A1,COC(=O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2F)cn1.COc1cc(F)ccc1O>>COC(=O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccc(F)cc2OC)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,val
+US07105558B2,BrC12CC3CC(CC(C3)C1)C2.C#CCO>>C#CCOC12CC3CC(CC(C3)C1)C2,,CCOC(C)=O,,CCN(CC)CC,,val
+US20150111870A1,COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1OCC(C)(C)OCc1ccccc1>>COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1OCC(C)(C)O,[Pd],CO,,,,val
+US20120184562A1,CC(C)(C)OC(=O)NCCC(N)c1ccccc1.COc1ccc2cc(C(=O)Nc3cc(C(=O)O)ccc3C)c(=O)[nH]c2n1>>COc1ccc2cc(C(=O)Nc3cc(C(=O)NC(CCNC(=O)OC(C)(C)C)c4ccccc4)ccc3C)c(=O)[nH]c2n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,val
+US06350907B1,COC[C@@H](N)c1ccccc1.COc1cccc(-c2ccc(CCCCCC[C@@H](C(=O)N[C@H](C(=O)O)C(C)(C)C)[C@@H]3OC(C)(C)OC3=O)cc2C)c1>>COC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCCCc1ccc(-c2cccc(OC)c2)c(C)c1)[C@@H]1OC(C)(C)OC1=O)C(C)(C)C)c1ccccc1,,CCOC(C)=O,,,,val
+US05696056,CC(=O)OC1COCC1OC(=O)C(C)Nc1cc(N)c(F)cc1Cl.O=C1OC(=O)c2ccccc21>>CC(=O)OC1COCC1OC(=O)C(C)Nc1cc(N2C(=O)c3ccccc3C2=O)c(F)cc1Cl,,O,,CC(=O)O,,val
+US06197729B1,OC(c1ccc(OCc2ccccc2)cc1)C(F)(F)F>>Oc1ccc(C(O)C(F)(F)F)cc1,[Pd],CC(=O)O,,[H][H],,val
+US05225402,O.O=C(c1ccc(OCCCCC2CO2)cc1)N1CCC(N2C(=O)CCc3ccccc32)CC1>>O=C(c1ccc(OCCCCC(O)CO)cc1)N1CCC(N2C(=O)CCc3ccccc32)CC1,,C1COCCO1,O,O=S(=O)(O)O,O=C([O-])O.[Na+],val
+US20100273739A1,C#CCNS(=O)(=O)CCC.CCOC(=O)NC1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1Cc1ccc(Cl)c(Cl)c1>>CCCS(=O)(=O)NCC#Cc1ccc2c(c1)C(Cc1ccccc1)C(NC(C)=O)CC2,[Cu]I,C1COCCO1,,CCN(CC)CC,O,val
+US04323691,CCO.O=C(O)COc1ccc(C(=O)c2ccc(O)cc2)c(Cl)c1Cl>>CCOC(=O)COc1ccc(C(=O)c2ccc(O)cc2)c(Cl)c1Cl,,ClCCCl,,O=S(=O)(O)O,,val
+US04104386,CCO.CN(C)c1ccc(C#N)nn1.O>>CCOC(=O)c1ccc(N(C)C)nn1,,ClCCl,,[Na+].[OH-],,val
+US20090176786A1,CCNC(=O)N(C)c1ccc(SC(F)(F)F)cc1F.O=C(Cl)c1c(F)cccc1F>>CCN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(SC(F)(F)F)cc1F,,c1ccncc1,,CCOC(C)=O,O,val
+US05041232,COc1ccc(C=O)cc1.NS(=O)(=O)c1ccc(C(=O)O)cc1>>COc1ccc(C=NS(=O)(=O)c2ccc(C(=O)O)cc2)cc1,,Clc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,val
+US20070112005A1,CCN(C(C)C)C(C)C.CO.Nc1nccn2c(C3CCC3)nc(I)c12.O>>COC(=O)c1nc(C2CCC2)n2ccnc(N)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,val
+US20100256365A1,COc1cccc(C(=O)c2cn(C(=O)OC(C)(C)C)c3ncc(-c4cccs4)cc23)c1F>>O=C(c1cccc(O)c1F)c1c[nH]c2ncc(-c3cccs3)cc12,,ClCCl,,BrB(Br)Br,,val
+US05350760,COC(=O)CC1(CS[C@H](CCc2ccccc2C(C)(C)O)c2cccc(CO)c2)CC1>>COC(=O)CC1(CS[C@H](CCc2ccccc2C(C)(C)O)c2cccc(C=O)c2)CC1,O=[Mn]=O,CCOC(C)=O,,,,val
+US20140194469A1,COC(=O)c1ccc(Br)cc1Cl.OB(O)C1CC1>>COC(=O)c1ccc(C2CC2)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],val
+US20160145247A1,CCOC[C@@H](NC(=O)OC(C)(C)C)c1cccc(Br)c1.COC(=O)Cc1ccccc1OCc1cccc(B2OC(C)(C)C(C)(C)O2)c1>>CCOC[C@@H](N)c1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1,,CN(C)C=O,,,,val
+US20080214558A1,CN1CCN(c2ccc(Nc3nccc(Nc4cccc(CC#N)c4)n3)cc2C(F)(F)F)CC1.O=S(=O)(O)O>>CN1CCN(c2ccc(Nc3nccc(Nc4cccc(CC#N)c4)n3)cc2C(F)(F)F)CC1.O=S(=O)(O)O,,CC(C)O,,,,val
+US20020037888A1,CCC1(c2cccc(OC)c2)CCCCN(CCN=[N+]=[N-])C1=O.Cl>>CCC1(c2cccc(OC)c2)CCCCN(CCN)C1=O.Cl,[Pd],CO,,,,val
+US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1>>Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(C(=O)O)c1,,CCO,,[Na+].[OH-],,val
+US20040127494A1,CC(C)C[C@H](C(N)=O)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Cl)cc1>>CC(C)C[C@H](C(N)=O)N(CC(=O)O)S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,val
+US20110015156A1,O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1CO.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)OCN1C(=O)CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc21,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,val
+US20120316151A1,CC(C)(O)CCl.O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(-c3ccc4occc4c3)cc2)C1>>CC(C)(O)Cn1nc(C[C@@H]2CCN(C(=O)C3CC3)C2)n(-c2ccc(-c3ccc4occc4c3)cc2)c1=O,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[K+].[K+],val
+US20060189604A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(N)=O)C[C@@H]1OC(=O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(N)=O)C[C@@H]1O,,CO,,O=C([O-])[O-].[K+].[K+],,val
+US04658001,C=Cc1ccccc1.CCC(C)c1ccccc1OC(=O)NC.O=C(OOC(=O)c1ccccc1)c1ccccc1>>C=Cc1ccccc1.O=C([O-])O[O-],,CO,,O=O,,val
+US20100210636A1,COc1ccc(CN2C(=O)OC(CNC(=O)c3ccc(F)cc3)(C(F)(F)F)c3cc(I)ccc32)cc1.c1nc[nH]n1>>O=C1Nc2ccc(-n3cncn3)cc2C(CNC(=O)c2ccc(F)cc2)(C(F)(F)F)O1,I[Cu]I,CCOC(C)=O,CN(C)C=O,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],val
+US20110064892A1,Cc1cc(N)c(N)cn1.Cc1cc2c3c(cc(C)cc3c1)C(=O)C2=O>>Cc1cc2c3c(cc(C)cc3c1)-c1nc3cc(C)ncc3nc1-2,,CC(=O)O,,,,val
+US20090253758A1,Cc1c(N[C@@H](c2nnc(-c3ccc(F)c(O[Si](C)(C)C(C)(C)C)c3)o2)[C@H](C)O[Si](C)(C)C(C)(C)C)ccc(C#N)c1Cl>>Cc1c(N[C@@H](c2nnc(-c3ccc(F)c(O)c3)o2)[C@H](C)O)ccc(C#N)c1Cl,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],val
+US05798375,CI.COc1ccc([N+](=O)[O-])c(NC(=O)OC(C)(C)C)c1>>COc1ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c1,,CN(C)C=O,,[H-].[Na+],,val
+US20150376136A1,Cc1cccc(C)n1.O=C(Br)CBr>>O=C(CBr)c1ccc[nH]1,,ClC(Cl)Cl,,,,val
+US20150266867A1,COc1ccc(CN2C(=O)[C@@H](NC(=O)OCc3ccccc3)[C@H]2CNCCO)c(OC)c1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(CN2C(=O)[C@@H](NC(=O)OCc3ccccc3)[C@H]2CN2CCOC2=O)c(OC)c1,,ClC(Cl)Cl,,,,val
+US20100216860A1,CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(C)=O)cccc32)c1>>CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(C)O)cccc32)c1,,CO,,Cl,[BH4-].[Na+],val
+US20140088101A1,COC(=O)c1nc(C#N)c2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O.NCc1ccncc1>>N#Cc1nc(C(=O)NCc2ccncc2)c(O)c2cc(-c3ccccc3)c(=O)n(Cc3ccccc3)c12,,CCO,,CC(=O)O,O,val
+US07238714B2,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(C#N)ccc2Oc2cccc(F)c2)cc1>>C[C@H](NC(=O)c1cc(C#N)ccc1Oc1cccc(F)c1)c1ccc(C(=O)O)cc1,,ClCCl,,BrB(Br)Br,O,val
+US20080108102A1,CCI.CN(C)c1ccc(-c2ccncc2)cc1>>CC[n+]1ccc(-c2ccc(N(C)C)cc2)cc1.[I-],,CC#N,,CCOCC,,val
+US20130029962A1,CC(C)(C)[Si](C)(C)OCCc1ccc(NC(=O)NCc2cc(C(F)(F)F)nn2-c2cccc(Cl)c2)cn1>>O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)Nc1ccc(CCO)nc1,,C1CCOC1,,Cl,,val
+US20090324581A1,COC(=O)c1ccc(C(C)C)c(OC(F)(F)F)c1>>CC(C)c1ccc(CO)cc1OC(F)(F)F,,C1CCOC1,,Cl,[BH4-].[Li+],val
+US20020028832A1,CCCCCCCCNC(=O)N1CCC(C(=O)N2CCC(Nc3ccc(CCNC[C@H](O)COc4ccc(O[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)cc4)cc3)CC2)CC1>>CCCCCCCCNC(=O)N1CCC(C(=O)N2CCC(Nc3ccc(CCNC[C@H](O)COc4ccc(O)cc4)cc3)CC2)CC1,,CO,ClC(Cl)Cl,,,val
+US20130225524A1,COC(=O)c1cc(Nc2c(C(N)=O)cnc3cc(-c4ccc(OC)nc4OC)ccc23)cc(C(=O)OC)c1>>COc1ccc(-c2ccc3c(Nc4cc(C(=O)O)cc(C(=O)O)c4)c(C(N)=O)cnc3c2)c(OC)n1,,CCO,,[Na+].[OH-],,val
+US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=S(=O)(O)O>>COc1cc(O)c2c(c1C(=O)O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,O=N[O-].[Na+],,val
+US20110183985A1,CC(=O)c1cc(Cl)c2cccnc2c1N1CCNCC1.COCC(=O)Cl>>COCC(=O)N1CCN(c2c(C(C)=O)cc(Cl)c3cccnc23)CC1,,ClCCl,ClCCl,CCN(CC)CC,,val
+US20080280337A1,CC(C)=CCCC(C)=CC=O>>CC(C)=CCCC(C)CC=O,,Cc1ccccc1,,CC(C)O,,val
+US20070099990A1,CI.Cc1cc(C)c(Cc2ccc(C(C)C)cc2)c(O)c1>>COc1cc(C)cc(C)c1Cc1ccc(C(C)C)cc1,,CN(C)C=O,,O,[H-].[Na+],val
+US20160272628A1,CC(=O)N(C)CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1C(C)(C)C>>CC(=O)N(C)CC1NS(=O)(=O)c2ccc(-c3c[nH]c4cc(F)ccc34)cc21,,O=C(O)C(F)(F)F,,,,val
+US20100099673A1,O=C(OCc1ccccc1)N1CCC(O)(c2ccccc2)[C@@H]2CCCC[C@@H]21>>OC1(c2ccccc2)CCN[C@H]2CCCC[C@H]21,[Pd],CCO,,,,val