The following are multiple choice questions (with answers) about medical knowledge.   **Question:** A 14-year-old boy is brought to the physician because of an increasing difficulty in hearing over the past several months. His mother says they have to speak at a higher volume for him to understand them. He also complains of having difficulty reading his favorite books because he is not able to see the words clearly. His father received a renal transplant in his 20s. The vital signs are within normal limits. The physical examination shows no abnormalities. Laboratory studies show: Serum Urea nitrogen 15 mg/dL Creatinine 1.0 mg/dL Urine Blood 1+ Protein 1+ RBC 15–17/hpf WBC 1–2/hpf The audiometry shows bilateral high-frequency sensorineural hearing loss. The ophthalmologic examination shows anterior lenticonus. Which of the following best explains these findings?   (A) Alport syndrome   (B) Fabry’s disease   (C) Von Hippel-Lindau disease   (D) Tuberous sclerosis
['(A) Alport syndrome <> answer', 'The following are multiple choice questions (with answers) about medical knowledge. <> instruction', '(A) Alport syndrome \n (B) Fabry’s disease \n (C) Von Hippel-Lindau disease \n (D) Tuberous sclerosis <> possible answers', '  A 14-year-old boy is brought to the physician because of an increasing difficulty in hearing over the past several months. His mother says they have to speak at a higher volume for him to understand them. He also complains of having difficulty reading his favorite books because he is not able to see the words clearly. His father received a renal transplant in his 20s. The vital signs are within normal limits. The physical examination shows no abnormalities. Laboratory studies show:\nSerum\nUrea nitrogen 15 mg/dL\nCreatinine 1.0 mg/dL\nUrine\nBlood 1+\nProtein 1+\nRBC 15–17/hpf\nWBC 1–2/hpf\nThe audiometry shows bilateral high-frequency sensorineural hearing loss. The ophthalmologic examination shows anterior lenticonus. Which of the following best explains these findings? <> context@']