The following are multiple choice questions (with answers) about medical knowledge.   **Question:** A 47-year-old woman comes to the physician because of progressive muscle weakness for five months. She feels that the muscles in her shoulders and hips have been getting weaker and sometimes feel sore. She now has difficulty getting up from chairs, climbing stairs, and combing her hair. She has also noticed new difficulty with swallowing solid foods, but has no trouble with liquids. She has a 5-year history of hyperlipidemia controlled with fluvastatin. Her maternal uncle died at age 26 from Duchenne's muscular dystrophy and her mother has Hashimoto's thyroiditis. Vital signs are within normal limits. Neurologic examination shows moderate weakness in the arm abductors and hip flexors bilaterally. Deep tendon reflexes are 2+ bilaterally. Laboratory studies show: Hemoglobin 13.7 g/dL Leukocytes 11,200/mm3 Erythrocyte sedimentation rate 33 mm/h Serum Creatine kinase 212 U/L Lactate dehydrogenase 164 U/L AST 34 U/L ALT 35 U/L Which of the following is most likely to confirm the diagnosis?"   (A) Intrafascicular infiltration on muscle biopsy   (B) Perifascicular and perivascular infiltration on muscle biopsy   (C) Positive anti-acetylcholine receptor antibodies   (D) Dystrophin gene mutation on genetic analysis
['(A) Intrafascicular infiltration on muscle biopsy <> answer', 'The following are multiple choice questions (with answers) about medical knowledge. <> instruction', '(A) Intrafascicular infiltration on muscle biopsy \n (B) Perifascicular and perivascular infiltration on muscle biopsy \n (C) Positive anti-acetylcholine receptor antibodies \n (D) Dystrophin gene mutation on genetic analysis <> possible answers', '  A 47-year-old woman comes to the physician because of progressive muscle weakness for five months. She feels that the muscles in her shoulders and hips have been getting weaker and sometimes feel sore. She now has difficulty getting up from chairs, climbing stairs, and combing her hair. She has also noticed new difficulty with swallowing solid foods, but has no trouble with liquids. She has a 5-year history of hyperlipidemia controlled with fluvastatin. Her maternal uncle died at age 26 from Duchenne\'s muscular dystrophy and her mother has Hashimoto\'s thyroiditis. Vital signs are within normal limits. Neurologic examination shows moderate weakness in the arm abductors and hip flexors bilaterally. Deep tendon reflexes are 2+ bilaterally. Laboratory studies show:\nHemoglobin 13.7 g/dL\nLeukocytes 11,200/mm3\nErythrocyte sedimentation rate 33 mm/h\nSerum\nCreatine kinase 212 U/L\nLactate dehydrogenase 164 U/L\nAST 34 U/L\nALT 35 U/L\nWhich of the following is most likely to confirm the diagnosis?" <> context@']