input: The following are multiple choice questions (with answers) about medical knowledge.   **Question:** Major determinant of loading dose of a drug is:-   (A) Half life   (B) Clearance   (C) Volume of distribution   (D) Bioavailability
output: ['(C) Volume of distribution <> answer', 'The following are multiple choice questions (with answers) about medical knowledge. <> instruction', '(A) Half life  (B) Clearance  (C) Volume of distribution  (D) Bioavailability <> possible answers', '  Major determinant of loading dose of a drug is:- <> context']