input: The following are multiple choice questions (with answers) about medical knowledge.   **Question:** Which of the following leads to an increase in enzyme activity -   (A) Increase in temperature   (B) Decrease in activation energy   (C) Extremes of pH value   (D) Low substrate concentration
output: ['(B) Decrease in activation energy <> answer', 'The following are multiple choice questions (with answers) about medical knowledge. <> instruction', '(A) Increase in temperature  (B) Decrease in activation energy  (C) Extremes of pH value  (D) Low substrate concentration <> possible answers', '  Which of the following leads to an increase in enzyme activity - <> context']